Steroid receptor induction of gene transcription: A two-step model

Gene regulation by steroid hormones

1989 • 3,466 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

1990 • 1,835 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

1996 • 1,769 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Nuclear receptor coactivators and corepressors.

1996 • 917 citations

Neurosteroids: of the nervous system, by the nervous system, for the nervous system.

1997 • 643 citations

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

1996 • 556 citations

Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.

1997 • 534 citations

Steroid receptors and their associated proteins.

1993 • 513 citations

The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

1996 • 453 citations

A regulatory system for use in gene transfer.

1994 • 434 citations

CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.

1996 • 414 citations

Transcription Factor Loading on the MMTV Promoter: A Bimodal Mechanism for Promoter Activation

1992 • 411 citations

p300 is a component of an estrogen receptor coactivator complex.

1996 • 399 citations

The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

1992 • 381 citations

Targeting Chromatin Disruption: Transcription Regulators that Acetylate Histones

1996 • 369 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).

1992 • 354 citations

Chromatin structure and gene expression.

1996 • 339 citations

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.

1993 • 328 citations

A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor.

1992 • 302 citations

Histone Deacetylase: A Regulator of Transcription

1996 • 298 citations

Histone Acetylation and Chromatin Assembly: A Single Escort, Multiple Dances?

1996 • 249 citations

Transcription: In tune with the histones

1994 • 239 citations

The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex

1990 • 223 citations

Identification of Human Proteins Functionally Conserved with the Yeast Putative Adaptors ADA2 and GCN5

1996 • 182 citations

Nucleosome displacement in transcription

1993 • 179 citations

Determinants of chromatin disruption and transcriptional regulation instigated by the thyroid hormone receptor: hormone-regulated chromatin disruption is not sufficient for transcriptional activation

1997 • 149 citations

Chromatin: Histone acetyltransferases in control

1997 • 139 citations

Micrococcal nuclease digestion of nuclei reveals extended nucleosome ladders having anomalous DNA lengths for chromatin assembled on non-replicating plasmids in transfected cells

1994 • 119 citations

Expression of Functional Chicken Oviduct Progesterone Receptors in Yeast (Saccharomyces Cerevisiae)

1989 • 111 citations

Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription

1990 • 110 citations

The World Wide Web as an Instructional Tool

1996 • 100 citations

Regulation of gene expression by nucleosomes

1996 • 66 citations

Interplay of steroid hormone receptors and transcription factors on the mouse mammary tumor virus promoter

1992 • 53 citations

Hormone activation of baculovirus expressed progesterone receptors.

1992 • 38 citations

DNA sequence affects nucleosome ordering on replicating plasmids in transfected COS-1 cells and in vitro.

1994 • 25 citations

The hormone responsive region of mouse mammary tumor virus positions a nucleosome and precludes access of nuclear factor I to the promoter

1996 • 23 citations

Promoter Specific Activating Domains of the Chicken Progesterone Receptor

1989 • 12 citations