A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

1995 • 3,603 citations

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

1994 • 3,477 citations

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1990 • 3,462 citations

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

1994 • 2,176 citations

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat.

1996 • 2,130 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.

1994 • 1,410 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

1993 • 940 citations

The eicosanoids and their biochemical mechanisms of action

1989 • 882 citations

Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor.

1992 • 863 citations

Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation.

1994 • 827 citations

Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.

1982 • 588 citations

Prostanoid biosynthesis and mechanisms of action

1992 • 551 citations

Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping.

1995 • 397 citations

A Simple Free Fat Cell Bioassay for Insulin

1974 • 365 citations

Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.

1983 • 334 citations

Organelle relationships in cultured 3T3-L1 preadipocytes.

1980 • 328 citations

Prostaglandin D2 formation and characterization of its synthetases in various tissues of adult rats

1988 • 258 citations

Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene.

1994 • 226 citations

The major source of endogenous prostaglandin D2 production is likely antigen-presenting cells. Localization of glutathione-requiring prostaglandin D synthetase in histiocytes, dendritic, and Kupffer cells in various rat tissues.

1989 • 221 citations

Biological activities and mechanisms of action of PGJ2 and related compounds: an update

1992 • 188 citations

The biology and pharmacology of PGD2

1988 • 174 citations

Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine.

1988 • 149 citations

Site and mechanism of growth inhibition by prostaglandins. III. Distribution and binding of prostaglandin A2 and delta 12-prostaglandin J2 in nuclei.

1987 • 140 citations

Purification and properties of prostaglandin D synthetase from rat brain.

1979 • 126 citations

The biosynthesis and possible function of prostaglandins in adipose tissue

1970 • 106 citations

The nucleotide sequence of the rat liver fatty acid-binding protein gene. Evidence that exon 1 encodes an oligopeptide domain shared by a family of proteins which bind hydrophobic ligands.

1986 • 100 citations

Peroxisome proliferator-activated receptors A link between endocrinology and nutrition?

1993 • 80 citations

A systematic analytical chemistry/cell assay approach to isolate activators of orphan nuclear receptors from biological extracts: characterization of peroxisome proliferator-activated receptor activators in plasma

1993 • 75 citations

Preferential binding of growth inhibitory prostaglandins by the target protein of a carcinogen.

1990 • 72 citations

Prostacyclin Production by Isolated Adipocytes

1981 • 49 citations

Phospholipase A2 is a differentiation-dependent enzymatic activity for adipogenic cell line and adipocyte precursors in primary culture.

1990 • 30 citations

9-Deoxy-Δ9,Δ12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma

1984 • 26 citations

Human forearm and kidney conversion of arachidonic acid to prostaglandins

1979 • 26 citations

Prostaglandin D2 is the major prostaglandin of arachidonic acid metabolism in rat bone marrow homogenate

1980 • 23 citations

Characterization of arachidonic acid metabolic profiles in animal tissues by high-resolution gas chromatography-mass spectrometry

1984 • 23 citations

Evidence for Abnormal Prostaglandin Synthesis in Obese Zucker Rat Adipose Cell Cultures

1989 • 23 citations