TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Current protocols in molecular biology

1988 • 4,543 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

Steroid hormone receptors: Many Actors in search of a plot

1995 • 1,854 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Nonsteroid nuclear receptors: What Are genetic studies telling us about their role in real life?

1995 • 1,011 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.

1990 • 772 citations

Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

1995 • 756 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

1995 • 627 citations

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

1988 • 588 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.

1992 • 441 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

1995 • 431 citations

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1995 • 429 citations

Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

1996 • 410 citations

Synergistic action of the glucocorticoid receptor with transcription factors.

1988 • 407 citations

Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

1994 • 402 citations

Interaction of proteins with transcriptionally active estrogen receptors.

1994 • 379 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions.

1992 • 359 citations

Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity.

1994 • 354 citations

From embryogenesis to metamorphosis: The regulation and function of drosophila nuclear receptor superfamily members

1995 • 347 citations

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

1992 • 341 citations

Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor.

1990 • 333 citations

Transcription factors 3: nuclear receptors.

1995 • 327 citations

Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor.

1994 • 324 citations

RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.

1993 • 305 citations

The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific

1989 • 299 citations

RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.

1995 • 257 citations

v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA

1990 • 236 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor

1995 • 154 citations

Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

1995 • 114 citations

Mouse Retinoid X Receptor Contains a Separable Ligand-Binding and Transactivation Domain in Its E Region

1995 • 95 citations

Pure and functionally homogeneous recombinant retinoid X receptor.

1994 • 62 citations