Molecular mechanisms of alcohol-mediated carcinogenesis

Comparative quantification of health risks : global and regional burden of disease attributable to selected major risk factors

2004 • 3,275 citations

IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans

1980 • 3,166 citations

NF-κB: linking inflammation and immunity to cancer development and progression

2005 • 2,878 citations

NF-κB functions as a tumour promoter in inflammation-associated cancer

2004 • 2,370 citations

ALCOHOL HEALTH AND RESEARCH WORLD

1983 • 1,968 citations

Estrogen Carcinogenesis in Breast Cancer

2006 • 1,780 citations

Alcohol, oxidative stress and free radical damage

2006 • 1,140 citations

IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis

2005 • 1,125 citations

Histone Deacetylase Inhibitors: Overview and Perspectives

2007 • 1,117 citations

DNA methylation and gene silencing in cancer

2005 • 1,110 citations

A meta-analysis of alcohol consumption and the risk of 15 diseases

2004 • 1,068 citations

Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis

1994 • 1,065 citations

Alcohol, tobacco and breast cancer – collaborative reanalysis of individual data from 53 epidemiological studies, including 58 515 women with breast cancer and 95 067 women without the disease

2002 • 1,016 citations

Alcohol Drinking in Never Users of Tobacco, Cigarette Smoking in Never Drinkers, and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium

2007 • 1,006 citations

Cytokines in Alcoholic and Nonalcoholic Steatohepatitis

2000 • 936 citations

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells

2006 • 911 citations

-Tocopherol and beta-Carotene Supplements and Lung Cancer Incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: Effects of Base-line Characteristics and Study Compliance

1996 • 884 citations

Carcinogenicity of alcoholic beverages

2007 • 844 citations

TGF-β signaling: positive and negative effects on tumorigenesis

2002 • 830 citations

Alcohol and cancer

2006 • 789 citations

Alcohol, Low-Methionine-Low-Folate Diets, and Risk of Colon Cancer in Men

1995 • 703 citations

TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis

1998 • 630 citations

Alcohol and hepatocellular carcinoma

2004 • 588 citations

Histone deacetylase (HDAC) inhibitor activation of p21 ^WAF1 involves changes in promoter-associated proteins, including HDAC1

2004 • 539 citations

How does DNA methylation repress transcription?

1997 • 532 citations

Alcohol and the liver: 1994 update

1994 • 511 citations

Alcohol Intake and Colorectal Cancer: A Pooled Analysis of 8 Cohort Studies

2004 • 506 citations

Alcohol and Breast Cancer

2001 • 500 citations

Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology

2004 • 489 citations

Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair

2006 • 484 citations

Imatinib mesylate blocks a non‐Smad TGF‐β pathway and reduces renal fibrogenesis in vivo

2005 • 452 citations

Polymorphisms in Genes Involved in Folate Metabolism and Colorectal Neoplasia: A HuGE Review

2004 • 449 citations

Microsomal Ethanol‐Oxidizing System (MEOS): The First 30 Years (1968‐1998)–A Review

1999 • 428 citations

ALCOHOL AND CANCER

2004 • 423 citations

Alcoholic beverage consumption in relation to risk of breast cancer: meta-analysis and review

1994 • 416 citations

Effects of Alcohol Consumption on Plasma and Urinary Hormone Concentrations in Premenopausal Women

1993 • 400 citations

Exploring the dose‐response relationship between alcohol consumption and the risk of several alcohol‐related conditions: a meta‐analysis

1999 • 395 citations

Cyclooxygenases in cancer: progress and perspective

2004 • 391 citations

Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics

1998 • 361 citations

Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts

1996 • 345 citations

Hepatic Vitamin A Depletion in Alcoholic Liver Injury

1982 • 343 citations

Progenitor Cells in Diseased Human Liver

2003 • 330 citations

The burden of cancer attributable to alcohol drinking

2006 • 326 citations

Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer

2000 • 319 citations

High acetaldehyde levels in saliva after ethanol consumption: methodological aspects and pathogenetic implications

1997 • 318 citations

Creation of genomic methylation patterns

1996 • 313 citations

Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress

2006 • 313 citations

European Code Against Cancer and scientific justification: third version (2003)

2003 • 309 citations

Contribution of mitochondria to oxidative stress associated with alcoholic liver disease1 1This article is part of a series of reviews on “Alcohol, Oxidative Stress and Cell Injury”. The full list of papers may be found on the homepage of the journal.

2002 • 289 citations

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice

2008 • 286 citations

Free radical adducts induce alterations in DNAcytosine methylation.

1994 • 282 citations

Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers

1997 • 281 citations

Early Hepatocellular Carcinoma and Dysplastic Nodules

2005 • 277 citations

Ethanol Consumption Inhibits Fetal DNA Methylation in Mice: Implications for the Fetal Alcohol Syndrome

1991 • 274 citations

The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

2002 • 272 citations

Combined effect of tobacco and alcohol on laryngeal cancer risk: a case-control study.

2002 • 266 citations

Linkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism

1999 • 258 citations

Serum Hormones and the Alcohol-Breast Cancer Association in Postmenopausal Women

2001 • 255 citations

Pooled Analysis of Alcohol Dehydrogenase Genotypes and Head and Neck Cancer: A HuGE Review

2003 • 248 citations

DNA Adducts with Lipid Peroxidation Products

2008 • 246 citations

Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers

1997 • 239 citations

Inhalation toxicity of acetaldehyde in rats. III. Carcinogenicity study☆

1986 • 234 citations

Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat

1990 • 233 citations

Formation of 1,N6-Ethenoadenine and 3,N4-Ethenocytosine by Lipid Peroxidation Products and Nucleic Acid Bases

1995 • 220 citations

Effects of Alcohol Ingestion on Estrogens in Postmenopausal Women

1996 • 219 citations

Identification of DNA Adducts of Acetaldehyde

2000 • 216 citations

High Salivary Acetaldehyde After a Moderate Dose of Alcohol in ALDH2‐Deficient Subjects: Strong Evidence for the Local Carcinogenic Action of Acetaldehyde

2000 • 207 citations

A mutagenicity assessment of acetaldehyde

1988 • 206 citations

Gene-environment interaction between an aldehyde dehydrogenase-2 (ALDH2) polymorphism and alcohol consumption for the risk of esophageal cancer

2001 • 201 citations

Direct interaction of GD3 ganglioside with mitochondria generates reactive oxygen species followed by mitochondrial permeability transition, cytochrome c release, and caspase activation

2000 • 199 citations

Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration in saliva

2004 • 196 citations

Acetaldehyde, Microbes, and Cancer of the Digestive Tract

2003 • 190 citations

Poor dental status increases acetaldehyde production from ethanol in saliva: a possible link to increased oral cancer risk among heavy drinkers

2001 • 187 citations

Evidence for an Important Role of Alcohol- and Aldehyde-Metabolizing Genes in Cancers of the Upper Aerodigestive Tract

2006 • 185 citations

Dynamics of cytochrome P4502E1 activity in man: induction by ethanol and disappearance during withdrawal phase

2002 • 182 citations

1,N⁶-Ethenodeoxyadenosine, a DNA Adduct Highly Mutagenic in Mammalian Cells

1996 • 178 citations

Formation, Detection, and Role In Carcinogenesis of Ethenobases in Dna

1994 • 167 citations

Inhibition of Ethanol-Induced Liver Disease in the Intragastric Feeding Rat Model by Chlormethiazole

2000 • 165 citations

Respiratory tract tumours in hamsters exposed to acetaldehyde vapour alone or simultaneously to benzo(a)pyrene or diethylnitrosamine

1982 • 164 citations

In vitro and in vivo inhibitory effect of ethanol and acetaldehyde on O⁶-methylguanine transferase

1988 • 164 citations

Mechanisms of alcohol-induced hepatic fibrosis: A summary of the Ron Thurman Symposium

2006 • 161 citations

Alcohol stimulates estrogen receptor signaling in human breast cancer cell lines.

2000 • 154 citations

Cocarcinogenic effects of alcohol in hepatocarcinogenesis

2002 • 153 citations

The effect of chronic habitual alcohol intake on the development of liver cirrhosis and hepatocellular carcinoma: Relation to hepatitis B surface antigen carriage

1982 • 153 citations

Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage

2002 • 153 citations

Alcohol and the Gastrointestinal Tract

1980 • 151 citations

Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver

2005 • 151 citations

Case-control study on hepatitis C virus (HCV) as a risk factor for hepatocellular carcinoma: The role of HCV genotypes and the synergism with hepatitis B virus and alcohol

1999 • 150 citations

Effects of Acetaldehyde on Cell Regeneration and Differentiation of the Upper Gastrointestinal Tract Mucosa

1997 • 149 citations

Neutrophilic infiltration in alcoholic hepatitis

2002 • 147 citations

Increased DNA Damage in ALDH2-Deficient Alcoholics

2006 • 144 citations

Laryngeal and oropharyngeal cancer, and alcohol dehydrogenase 3 and glutathione S-transferase M1 polymorphisms

1997 • 139 citations

Role of alcohol dehydrogenase 3 and cytochrome P-4502E1 genotypes in susceptibility to cancers of the upper aerodigestive tract

2000 • 134 citations

Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation

2006 • 134 citations

Chronic alcohol intake reduces retinoic acid concentration and enhances AP-1 (c-Jun and c-Fos) expression in rat liver

1998 • 134 citations

Effect of ethanol on the tumorigenicity of urethane (ethyl carbamate) in B6C3F1 mice

2004 • 133 citations

Chronic Alcohol Consumption Induces Genomic but Not p53-Specific DNA Hypomethylation in Rat Colon

1999 • 132 citations

Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehyde

2005 • 130 citations

Development of a ³²P-postlabelling method for the analysis of adducts arising through the reaction of acetaldehyde with 2′-deoxyguanosine-3′-monophosphate and DNA

1995 • 130 citations

Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1

2001 • 129 citations

Mutagenesis induced by a single 1,N6-ethenodeoxyadenosine adduct in human cells.

2000 • 129 citations

Identification of an Acetaldehyde Adduct in Human Liver DNA and Quantitation as N²-Ethyldeoxyguanosine

2006 • 127 citations

Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol‐associated cancer in heavy drinkers

2005 • 124 citations

Immunohistochemical localization of ethanol-inducible P450IIE1 in the rat alimentary tract

1990 • 118 citations

Metabolism of ethanol in vitro produces a compound which induces sister-chromatid exchanges in human peripheral lymphocytes in vitro: Acetaldehyde not ethanol is mutagenic

1986 • 118 citations

S‐Adenosylmethionine regulatesMAT1AandMAT2Agene expression in cultured rat hepatocytes: a new role for S‐adenosylmethionine in the maintenance of the differentiated status of the liver

2000 • 116 citations

Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells

2006 • 115 citations

Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde

2004 • 113 citations

Vegetable consumption, serum retinol level, and risk of hepatocellular carcinoma.

1995 • 112 citations

Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver

1992 • 111 citations

Specific tandem GG to TT base substitutions induced by acetaldehyde are due to intra-strand crosslinks between adjacent guanine bases

1998 • 108 citations

IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1

2001 • 107 citations

The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model

2008 • 106 citations

Effect of ethanol on proliferation and estrogen receptor-α expression in human breast cancer cells

2001 • 101 citations

Increased circulating products of lipid peroxidation in patients with alcoholic liver disease.

1998 • 98 citations

Increased frequency of acetaldehyde-induced sister-chromatic exchanges in human lymphocytes treated with an aldehyde dehydrogenase inhibitor

1991 • 95 citations

High intracolonic acetaldehyde values produced by a bacteriocolonic pathway for ethanol oxidation in piglets.

1996 • 94 citations

The ADH1C Polymorphism Modifies the Risk of Squamous Cell Carcinoma of the Head and Neck Associated with Alcohol and Tobacco Use

2005 • 93 citations

Liver‐specific methionine adenosyltransferaseMAT1Agene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications forMAT1Asilencing during transformation

2000 • 93 citations

In Vitro Alcohol Dehydrogenase‐Mediated Acetaldehyde Production by Aerobic Bacteria Representing the Normal Colonic Flora in Man

1996 • 93 citations

Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer risk.

1999 • 93 citations

Results of Long‐Term Experimental Studies on the Carcinogenicity of Methyl Alcohol and Ethyl Alcohol in Rats

2002 • 92 citations

Alcohol, vitamin A, and cancer

2005 • 91 citations

Genetic polymorphisms of cytochrome p4502E1 and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a white population: a study and literature review, including meta-analysis

2000 • 90 citations

Restoration of retinoic acid concentration supresses ethanol-enhanced c-Jun expression and hepatocyte proliferation in rat liver

2001 • 89 citations

Increased Circulating Products of Lipid Peroxidation in Patients with Alcoholic Liver Disease

1998 • 89 citations

Alcohol consumption, alcohol dehydrogenase 3 polymorphism, and colorectal adenomas.

2003 • 87 citations

Does oxidative stress participate in the development of hepatocellular carcinoma?

2007 • 87 citations

Effective Utilization of N²-Ethyl-2‘-deoxyguanosine Triphosphate during DNA Synthesis Catalyzed by Mammalian Replicative DNA Polymerases

1998 • 86 citations

Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-κB activity and TNF expression: relevance to alcoholic liver disease

2006 • 86 citations

Immunohistochemical detection of 1, N6 -ethenodeoxyadenosine in nuclei of human liver affected by diseases predisposing to hepato-carcinogenesis

2004 • 84 citations

Risk factors in alcohol associated breast cancer: alcohol dehydrogenase polymorphism and estrogens.

2004 • 83 citations

Increased formation of hepatic N2-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase 2-knockout mice treated with ethanol

2007 • 83 citations

Importance of a deficiency in S-adenosyl-l-methionine synthesis in the pathogenesis of liver injury,,,

2002 • 82 citations

Phase I/II enzyme gene polymorphisms and esophageal cancer risk: A meta-analysis of the literature

2005 • 80 citations

Ethanol, Acetaldehyde, Acetate, and Lactate Levels After Alcohol Intake in White Men and Women: Effect of 4‐Methylpyrazole

2002 • 79 citations

Genetic Polymorphisms of Alcohol and Aldehyde Dehydrogenases and Risk for Esophageal and Head and Neck Cancers

2005 • 78 citations

Oral squamous cell cancer risk in relation to alcohol consumption and alcohol dehydrogenase-3 genotypes.

2001 • 78 citations

Risk of head and neck cancer and the alcohol dehydrogenase 3 genotype

2001 • 77 citations

The Effects of Chronic Ethanol Consumption on Carcinogen Metabolism and on O6‐Methylguanine Transferase‐Mediated Repair of Alkylated DNA

1986 • 76 citations

Alcohol and the Gastrointestinal Tract

1996 • 75 citations

Enhancement of ethanol induced rectal mucosal hyper regeneration with age in F344 rats.

1994 • 75 citations

Estrogen‐Related Acetaldehyde Elevation in Women during Alcohol Intoxication

1996 • 74 citations

Risk of Squamous Cell Carcinoma of the Upper Aerodigestive Tract in Cancer-Free Alcoholic Japanese Men: An Endoscopic Follow-up Study

2006 • 74 citations

Multiple cancers associated with esophageal and oropharyngolaryngeal squamous cell carcinoma and the aldehyde dehydrogenase-2 genotype in male Japanese drinkers.

2002 • 74 citations

Low Km aldehyde dehydrogenase (ALDH2) polymorphism, alcohol-drinking behavior, and chromosome alterations in peripheral lymphocytes.

1996 • 73 citations

ADH3 genotype, alcohol intake and breast cancer risk

2005 • 72 citations

Hepatotoxicity of alcohol‐induced polar retinol metabolites involves apoptosis via loss of mitochondrial membrane potential

2005 • 70 citations

Importance of a deficiency in S-adenosyl-l-methionine synthesis in the pathogenesis of liver injury,,,

2002 • 69 citations

Increased cytogenetic damage detected by FISH analysis on micronuclei in peripheral lymphocytes from alcoholics

2000 • 69 citations

Laryngeal cancer risk in Caucasians is associated with alcohol and tobacco consumption but not modified by genetic polymorphisms in class I alcohol dehydrogenases ADH1B and ADH1C, and glutathione-S-transferases GSTM1 and GSTT1

2003 • 64 citations

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1982 • 64 citations

A prospective study of the effect of alcohol consumption and ADH3 genotype on plasma steroid hormone levels and breast cancer risk.

2000 • 64 citations

Vitamin B6 Intake, Alcohol Consumption, and Colorectal Cancer: A Longitudinal Population-Based Cohort of Women

2005 • 62 citations

Is mallory body formation a preneoplastic change? A study of 181 cases of liver bearing hepatocellular carcinoma and 82 cases of cirrhosis

1985 • 60 citations

Independent and joint effects of family history and lifestyle on colorectal cancer risk: implications for prevention.

1999 • 60 citations

Alcohol and the Risk of Cancers of the Stomach and Colon-Rectum

1994 • 59 citations

Increased rectal cell proliferation following alcohol abuse

2001 • 59 citations

Appearance of oval cells in the liver of rats after long-term exposure to ethanol

1996 • 58 citations

Alcohol consumption as A risk factor for hepatocellular carcinoma in urban Southern African blacks

1992 • 58 citations

Alcohol dehydrogenase 3 genotype is not associated with risk of squamous cell carcinoma of the oral cavity and pharynx.

2001 • 56 citations

Long‐Term Ethanol Consumption in ICR Mice Causes Mammary Tumor in Females and Liver Fibrosis in Males

2000 • 56 citations

Interaction between a single nucleotide polymorphism in the alcohol dehydrogenase 3 gene, alcohol consumption and oral cancer risk

2001 • 56 citations

Ethanol stimulates tumor progression and expression of vascular endothelial growth factor in chick embryos

2004 • 55 citations

Inhibition of Intracolonic Acetaldehyde Production and Alcoholic Fermentation in Rats by Ciprofloxacin

1998 • 54 citations

Increased Acetaldehyde Production by Mouthwashings from Patients with Oral Cavity, Laryngeal, or Pharyngeal Cancer

1996 • 54 citations

Histone acetyltransferase p300 modulates gene expression in an epigenetic manner at high blood alcohol levels

2007 • 54 citations

Alcohol and Colorectal Cancer: The Role of Alcohol Dehydrogenase 1C Polymorphism

2008 • 53 citations

Esophageal Epithelial Hyperproliferation Following Long-Term Alcohol Consumption in Rats: Effects of Age and Salivary Gland Function

1993 • 52 citations

Biomarkers to assess the genetic damage induced by alcohol abuse in human lymphocytes

2002 • 52 citations

In utero alcohol exposure increases mammary tumorigenesis in rats

2004 • 50 citations

Chlormethiazole Treatment Prevents Reduced Hepatic Vitamin A Levels in Ethanol‐Fed Rats

2002 • 49 citations

Ethanol and Experimental Breast Cancer: A Review

1997 • 48 citations

Effects of ALDH2 gene polymorphisms and alcohol-drinking behavior on micronuclei frequency in non-smokers

2003 • 47 citations

Ethanol stimulates proliferation, ERα and aromatase expression in MCF-7 human breast cancer cells

2004 • 43 citations

Alcohol consumption enhances liver metastasis in colorectal carcinoma patients

1998 • 43 citations

Role of Medium‐Chain Triglycerides in the Alcohol‐Mediated Cytochrome P450 2E1 Induction of Mitochondria

2007 • 43 citations

Alcohol Dehydrogenase 3 and Risk of Squamous Cell Carcinomas of the Head and Neck

2005 • 43 citations

MODULATION OF CANCER GROWTH BY VITAMIN E AND ALCOHOL

1993 • 42 citations

Ethanol promotes intestinal tumorigenesis in the MIN mouse. Multiple intestinal neoplasia.

2002 • 37 citations

Nitric Oxide and Liver Injury in Alcohol‐Fed Rats after Lipopolysaccharide Administration

1996 • 36 citations

Alcohol and risk of cancer of the upper gastrointestinal tract: first analysis of the EPIC data.

2002 • 33 citations

Presence of benzo[a]pyrene diol epoxide adducts in target DNA leads to an increase in UV-induced DNA single strand breaks and supF gene mutations

2001 • 30 citations

Enhancing effect of ethanol on esophageal tumor development in rats by initiation of diethylnitrosamine

1993 • 29 citations

Inhibition of alcohol-associated colonic hyperregeneration by alpha-tocopherol in the rat.

2003 • 26 citations

Characterization of ethanol's enhancement of tumorigenesis by N-nitrosodimethylamine in mice

1992 • 26 citations

Ethanol-induced ligand-independent activation of ERalpha mediated by cyclic AMP/PKA signaling pathway: an in vitro study on MCF-7 breast cancer cells.

2007 • 25 citations

Liver Diseases. Biochemical mechanisms and new therapeutic insights.

2006 • 24 citations

Alcohol Dehydrogenase 3 Genotype as a Risk Factor for Upper Aerodigestive Tract Cancers

2004 • 24 citations

Mallory body forming cells express the preneoplastic hepatocyte phenotype

2006 • 23 citations

Molecular Profiling of Hepatocellular Carcinoma in Mice with a Chronic Deficiency of Hepatic S-Adenosylmethionine: Relevance in Human Liver Diseases

2006 • 21 citations

Increased expression of integrin β1 subunit enhances p21^WAF1/Cip1 transcription through the Sp1 sites and p300‐mediated histone acetylation in human hepatocellular carcinoma cells

2007 • 19 citations

Alcohol, Tobacco and Cancer

2006 • 18 citations

Liver Diseases (2 Vols.)

2006 • 15 citations

Alcohol ingestion enhances hepatocarcinogenesis induced by synthetic estrogen and progestin in the rat.

1994 • 14 citations

Ethanol interactions with a choline-deficient, ethionine-supplemented feeding regime potentiate pre-neoplastic cellular alterations in rat liver

2002 • 14 citations

Effect of chronic dietary ethanol in the promotion of N‐nitrosomethylbenzylamine‐induced esophageal carcinogenesis in rats

2006 • 13 citations

Alcoholism services for minorities: training issues and concerns.

1978 • 10 citations

Alcohol and Retinoid Interaction

2004 • 9 citations

Alcohol and Cancer of the Large Intestine

2006 • 6 citations

The Flying to Pieces of a Whirling Ring

1891 • 6 citations