Increased cytogenetic damage detected by FISH analysis on micronuclei in peripheral lymphocytes from alcoholics

Measurement of micronuclei in lymphocytes

1985 • 1,807 citations

Catalog of chromosome aberrations in cancer

1985 • 1,522 citations

The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human populations

1993 • 990 citations

Identification of aneuploidy‐inducing agents using cytokinesis‐blocked human lymphocytes and an antikinetochore antibody

1989 • 645 citations

Genetic instability of cancer cells is proportional to their degree of aneuploidy

1998 • 378 citations

Chromosome aberrations, micronuclei, aneuploidy, sister chromatid exchanges, and cancer risk assessment

1996 • 333 citations

Chemically induced aneuploidy in mammalian cells: Mechanisms and biological significance in cancer

1986 • 260 citations

Aneuploidy vs. gene mutation hypothesis of cancer: Recent study claims mutation but is found to support aneuploidy

2000 • 253 citations

Sex chromosome loss and aging: in situ hybridization studies on human interphase nuclei.

1995 • 212 citations

Quantitating the synergistic effect of smoking and alcohol consumption with the micronucleus test on human buccal mucosa cells

1983 • 211 citations

DNA Damage, DNA Repair, and Alcohol Toxicity—A Review

1997 • 178 citations

Mouse lymphoma L5178Y thymidine kinase locus assay of 50 compounds

1988 • 161 citations

Use of fluorescence in situ hybridization (FISH) to assess effects of smoking, caffeine, and alcohol on aneuploidy load in sperm of healthy men

1997 • 154 citations

How aneuploidy affects metabolic control and causes cancer

1999 • 137 citations

Sex chromosome aneuploidy and aging

1995 • 128 citations

Chromosomal damage and ageing: effect on micronuclei frequency in peripheral blood lymphocytes

1999 • 125 citations

Micronucleated lymphocytes in people occupationally exposed to potential environmental contaminants: the age effect

1991 • 112 citations

Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes

1994 • 112 citations

Biological and environmental monitoring of occupational exposure to cyclophosphamide in industry and hospitals

1988 • 111 citations

Genetic effects of ethanol

1987 • 109 citations

Molecular cytogenetic analysis of buccal cells and lymphocytes from benzene-exposed workers

1997 • 106 citations

Cytogenetic analysis of a human population occupationally exposed to pesticides

1993 • 105 citations

Etiology of nondisjunction in humans

1995 • 104 citations

Ethanol-induced chromosomal abnormalities at conception

1983 • 103 citations

Medical and Nutritional Complications of Alcoholism: Mechanisms and Management

2011 • 102 citations

Medical and Nutritional Complications of Alcoholism

1992 • 96 citations

Measurement and characterization of micronuclei in exfoliated human cells by fluorescence in situ hybridization with a centromeric probe

1994 • 93 citations

Human micronucleus counts are correlated with age, smoking, and cesium-137 dose in the Goiânia (Brazil) radiological accident

1994 • 90 citations

A cytogenetic study of radiological workers: effect of age, smoking and radiation burden on the micronucleus frequency

1996 • 88 citations

Chromosome aberrations and micronuclei in bone marrow cells and peripheral blood lymphocytes in humans exposed to ethylene oxide

2008 • 87 citations

The detection and evaluation of aneugenic chemicals

1996 • 81 citations

Influence of smoking habit on the frequency of micronuclei in human lymphocytes by the cytokinesis block method

1991 • 75 citations

Chromosomal aberrations in peripheral lymphocytes of alcoholics

1980 • 75 citations

Age-associated micronuclei containing centromeres and the X chromosome in lymphocytes of women

1995 • 75 citations

The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens. Results from two laboratories

1994 • 73 citations

Low Km aldehyde dehydrogenase (ALDH2) polymorphism, alcohol-drinking behavior, and chromosome alterations in peripheral lymphocytes.

1996 • 73 citations

Use of a centromere‐specific DNA probe (p82H) in nonisotopic in situ hybridization for classification of micronuclei

1990 • 72 citations

Cytogenetic biomonitoring in traffic police workers: Micronucleus test in peripheral blood lymphocytes

1997 • 67 citations

Biological markers in PAH exposed workers and controls

1993 • 63 citations

Catalog of chromosome aberrations in cancer (5th edn)

1995 • 62 citations

Mitotic non-disjunction as a mechanism for in vitro aneuploidy induction by X-rays in primary human cells

1996 • 61 citations

No increase in micronuclei frequency in cultured blood lymphocytes from a group of filling station attendants

1996 • 58 citations

Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens

1996 • 58 citations

THE TERATOGENIC EFFECTS OF ALCOHOL FOLLOWING EXPOSURE DURING PREGNANCY, AND ITS INFLUENCE ON THE CHROMOSOME CONSTITUTION OF THE PRE-OVULATORY EGG

1997 • 51 citations

The frequency of micronuclei with X chromosome increases with age in human females

1994 • 51 citations

Increased frequency of sister-chromatid exchanges in alcoholics

1981 • 50 citations

Indicators of genetic damage in alcoholics: reversibility after alcohol abstinence.

1999 • 49 citations

Radioactive iodine induces clastogenic and age-dependent aneugenic effects in lymphocytes of thyroid cancer patients as revealed by interphase FISH

1997 • 45 citations

Influence of ethanol on chromosome segregation during the first and second meiotic divisions in the mouse egg

1984 • 39 citations

The use of fluorescence in situ hybridization with a β-satellite DNA probe for the detection of acrocentric chromosomes in vanadium-induced micronuclei

1995 • 39 citations

Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79

1997 • 36 citations

Significance of aneuploidy

1994 • 31 citations

A comparative study on ethanol and acetaldehyde as inducers of chromosome malsegregation in Aspergillus nidulans

1989 • 29 citations

Disruptive effects of ethyl alcohol on mitotic chromosome segregation in diploid and haploid strains of Aspergillus nidulans

1984 • 27 citations

Effects of benzo[a]pyrene and (±)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene on mitosis in Chinese hamster V79 cells with stable expression of rat cytochrome P4501A1 or 1A2

1993 • 26 citations

Evaluation of exposure reducing measures on parameters of genetic risk in a population occupationally exposed to coal fly ash

1993 • 25 citations

An hypothesis regarding the origin of aneuploidy in man: indirect evidence from an experimental model.

1985 • 21 citations

Change in centromeric and acentromeric micronucleus frequencies in human populations after chronic radiation exposure

1999 • 21 citations

A Follow‐Up Study on Chromosomal Aberrations in Lymphocytes of Alcoholics During Early, Medium, and Long‐Term Abstinence

1999 • 20 citations

Nondisjunction induced by ethanol in Drosophila melanogaster females

1992 • 16 citations

Alcohol Abuse: Carcinogenic Effects and Fetal Alcohol Syndrome

1992 • 15 citations

Epidemiology and pathophysiology of ethanol-associated gastrointestinal cancer

1992 • 13 citations

Increased sister chromatid exchange frequency in chronic alcoholic users

2008 • 11 citations

Chromosomal abnormalities in ascitic fluid from patients with alcoholic cirrhosis.

1981 • 9 citations