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Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration in saliva

Data up to Jan 2025

Published2004
Citations196
References41

Total Citations Per Year

Abstract

References (41)

IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans

1980 • 3,166 citations

Smoking and drinking in relation to oral and pharyngeal cancer.

1988 • 1,962 citations

Smoking and drinking in relation to cancers of the oral cavity, pharynx, larynx, and esophagus in northern Italy.

1990 • 589 citations

Epidemiology and prevention of oral cancer

1997 • 441 citations

Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans

1993 • 397 citations

Cancer of the larynx/hypopharynx, tobacco and alcohol: Iarc international case‐control study in Turin and Varese (Italy), Zaragoza and Navarra (Spain), Geneva (Switzerland) and Calvados (France)

1988 • 396 citations

Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics

1998 • 361 citations

Independent and joint effects of tobacco smoking and alcohol drinking on the risk of esophageal cancer in men and women

1999 • 357 citations

Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer

2000 • 319 citations

High acetaldehyde levels in saliva after ethanol consumption: methodological aspects and pathogenetic implications

1997 • 318 citations

Differential effects of tobacco and alcohol in cancer of the larynx, pharynx, and mouth

1986 • 295 citations

Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers

1997 • 239 citations

Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S-transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma

2002 • 229 citations

The relative toxicity of compounds in mainstream cigarette smoke condensate

2000 • 220 citations

High Salivary Acetaldehyde After a Moderate Dose of Alcohol in ALDH2‐Deficient Subjects: Strong Evidence for the Local Carcinogenic Action of Acetaldehyde

2000 • 207 citations

A mutagenicity assessment of acetaldehyde

1988 • 206 citations

Acetaldehyde, Microbes, and Cancer of the Digestive Tract

2003 • 190 citations

Acetaldehyde production by non-pathogenicNeisseria in human oral microflora: Implications for carcinogenesis in upper aerodigestive tract

2000 • 162 citations

Genetic Polymorphisms of Alcohol and Aldehyde Dehydrogenases and Risk for Esophageal and Head and Neck Cancers

2003 • 157 citations

Effects of Acetaldehyde on Cell Regeneration and Differentiation of the Upper Gastrointestinal Tract Mucosa

1997 • 149 citations

Carcinogenic effect of tobacco smoking and alcohol drinking on anatomic sites of the oral cavity and oropharynx

1992 • 136 citations

Role of alcohol dehydrogenase 3 and cytochrome P-4502E1 genotypes in susceptibility to cancers of the upper aerodigestive tract

2000 • 134 citations

Acetaldehyde in Mainstream Tobacco Smoke: Formation and Occurrence in Smoke and Bioavailability in the Smoker

2002 • 125 citations

Role of Yeasts in the Salivary Acetaldehyde Production From Ethanol Among Risk Groups for Ethanol‐Associated Oral Cavity Cancer

1999 • 119 citations

Metabolism of ethanol in vitro produces a compound which induces sister-chromatid exchanges in human peripheral lymphocytes in vitro: Acetaldehyde not ethanol is mutagenic

1986 • 118 citations

Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde

2004 • 113 citations

Association between aldehyde dehydrogenase gene polymorphisms and the phenomenon of field cancerization in patients with head and neck cancer

2002 • 101 citations

Increased frequency of acetaldehyde-induced sister-chromatic exchanges in human lymphocytes treated with an aldehyde dehydrogenase inhibitor

1991 • 95 citations

Contribution of oropharynx microflora and of lung microsomes to acetaldehyde in expired air after alcohol ingestion.

1981 • 81 citations

Alcohol consumption and cancer of the gastrointestinal tract

2003 • 80 citations

Formation of DNA adducts in human buccal epithelial cells exposed to acetaldehyde and methylglyoxal in vitro

1998 • 80 citations

Gastrointestinal Alcohol Dehydrogenase

2009 • 79 citations

Removal of acetaldehyde from saliva by a slow‐release buccal tablet of L‐cysteine

2001 • 73 citations

MEASURING AND REPORTING THE CONCENTRATION OF ACETALDEHYDE IN HUMAN BREATH

1995 • 66 citations

Oxidation of Ethanol to Acetaldehyde by Bronchopulmonary Washings: Role of Bacteria

1986 • 58 citations

Increased Acetaldehyde Production by Mouthwashings from Patients with Oral Cavity, Laryngeal, or Pharyngeal Cancer

1996 • 54 citations

Genetic Polymorphism of Aldehyde Dehydrogenase 2 in Patients With Upper Aerodigestive Tract Cancer

1999 • 36 citations

Origin of breath acetaldehyde during ethanol oxidation. Effect of long-term cigarette smoking.

1982 • 34 citations

The effect of cigarette smoking on breath and whole blood-associated acetaldehyde

1990 • 29 citations

Comparison of Blood Aldehyde Dehydrogenase Activities in Moist Snuff Users, Cigarette Smokers and Nontobacco Users

1991 • 21 citations

Elevated endogenous breath acetaldehyde levels among abusers of alcohol and cigarettes

1985 • 14 citations

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Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration… (2004) – International Journal of Cancer | Metascience Observatory Explorer