Mutagenesis induced by a single 1,N6-ethenodeoxyadenosine adduct in human cells.

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

DNA Repair and Mutagenesis

2006 • 4,725 citations

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

1999 • 1,273 citations

Hybridization of synthetic oligodeoxyribonucleotides to Φ_X174 DNA: the effect of single base pair mismatch

1979 • 753 citations

Endogenous mutagens and the causes of aging and cancer

1991 • 725 citations

Biological and biochemical properties of human rasH genes mutated at codon 61

1986 • 538 citations

UmuD′ ₂ C is an error-prone DNA polymerase, Escherichia coli pol V

1999 • 524 citations

Isolation and Characterization of a Human Liver cDNA as a Candidate Gene for Wilson Disease

1993 • 501 citations

Biochemical Basis of DNA Replication Fidelity

1993 • 441 citations

Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

1999 • 425 citations

Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells.

1993 • 407 citations

Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts

1996 • 345 citations

A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase ζ

1998 • 300 citations

Activating mutations of the c-Ha-ras protooncogene in chemically induced hepatomas of the male B6C3 F1 mouse.

1986 • 250 citations

1,N⁶-Ethenodeoxyadenosine and 3,N⁴-ethenodeoxycytidine in liver DNA from humans and untreated rodents detected by immunoaffinity/³²P-postlabelling

1995 • 212 citations

Escherichia coil,Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N⁶-ethenoadenine when present in DNA

1995 • 208 citations

p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers

1994 • 199 citations

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

1998 • 189 citations

1,N⁶-Ethenodeoxyadenosine, a DNA Adduct Highly Mutagenic in Mammalian Cells

1996 • 178 citations

Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole

1993 • 174 citations

Formation, Detection, and Role In Carcinogenesis of Ethenobases in Dna

1994 • 167 citations

All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase.

1994 • 148 citations

Mutations in the mutY gene of Escherichia coli enhance the frequency of targeted G:C → T:A transversions induced by a single 8-oxoguanine residue in single-stranded DNA

1993 • 141 citations

Cancer risk following primary hemochromatosis: A population‐based cohort study in Denmark

1995 • 140 citations

Anti-p53 Antibodies in Sera of Workers Occupationally Exposed to Vinyl Chloride

1995 • 138 citations

Lipid peroxidation-induced etheno-DNA adducts in the liver of patients with the genetic metal storage disorders Wilson's disease and primary hemochromatosis.

1998 • 115 citations

Greater Susceptibility to Mutations in Lagging Strand of DNA Replication in Escherichia coli than in Leading Strand

1993 • 108 citations

Mutagenicity of a unique apurinic/apyrimidinic site in mammalian cells

1992 • 101 citations

Cleavage of Bacteriophage f1 DNA by the Restriction Enzyme of Escherichia coli B

1972 • 95 citations

The LEC rat: a model for human hepatitis, liver cancer, and much more.

1994 • 92 citations

Studies on the miscoding properties of 1,N⁶-ethenoadenine and 3,N⁴-ethenocytosine, DNA reaction products of vinyl chloride metabolites, during in vitro DNA synthesis

1981 • 87 citations

The ability of large T antigen to complex with p53 is necessary for the increased life span and partial transformation of human cells by simian virus 40

1991 • 81 citations

Etheno adducts in spleen DNA of SJL mice stimulated to overproduce nitric oxide

1998 • 78 citations

p53 gene mutation pattern in rat liver tumors induced by vinyl chloride.

1997 • 69 citations

Mechanism of mutation on DNA templates containing synthetic abasic sites: study with a double strand vector

1994 • 67 citations

Assessment of mutagenic efficiency of two carcinogen-modified nucleosides, 1,N⁶-ethenodeoxyadenosine and O⁴-methyldeoxythymidine, using polymerases of varying fidelity

1984 • 53 citations

Mutagenesis of ras proto-oncogenes in rat liver tumors induced by vinyl chloride.

1994 • 44 citations

High frequency of K-ras mutations in spontaneous and vinyl carbamate-induced lung tumors of relatively resistant B6CF1 (C57BL/6J×BALB/cJ) mice

1995 • 40 citations

Stable T-p53 complexes are not required for replication of simian virus 40 in culture or for enhanced phosphorylation of T antigen and p53

1991 • 37 citations

Transformation of NIH3T3 Cells with Synthetic c‐Ha‐ras Genes

1989 • 20 citations

Quantitation of 1,N⁶-Ethenoadenine in Rat Urine by Immunoaffinity Extraction Combined with Liquid Chromatography/Electrospray Ionization Mass Spectrometry

1998 • 17 citations