Inhibition of Ethanol-Induced Liver Disease in the Intragastric Feeding Rat Model by Chlormethiazole

Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)

1989 • 527 citations

Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet

1985 • 236 citations

Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors

1995 • 164 citations

Effects of Chronic Ethanol Administration on Rat Liver Proteasome Activities: Relationship With Oxidative Stress

1999 • 130 citations

Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans

1997 • 94 citations

Zonated expression of cytokines in rat liver: Effect of chronic ethanol and the cytochrome P450 2E1 inhibitor, chlormethiazole

1998 • 91 citations

Peptidase activities of the multicatalytic protease in rat liver after voluntary and intragastric ethanol administration

1998 • 73 citations

Proteolytic Degradation of Heme-Modified Hepatic Cytochromes P450: A Role for Phosphorylation, Ubiquitination, and the 26S Proteasome?

1999 • 70 citations

Chlormethiazole as an efficient inhibitor of cytochrome P450 2E1 expression in rat liver.

1994 • 68 citations

CYP-2E1 inhibitors partially ameliorate the changes in hepatic fatty acid composition induced in rats by chronic administration of ethanol and a high fat diet.

1995 • 67 citations

[12] Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1

1996 • 66 citations

Autoantibodies against Cytochromes P-4502E1 and P-4503A in Alcoholics

1999 • 66 citations

Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors*1

1995 • 48 citations

Identification of a ubiquitination-Target/Substrate-interaction domain of cytochrome P-450 (CYP) 2E1.

2000 • 42 citations

Effects of cytochrome p450 2E1 modulators on the pharmacokinetics of chlorzoxazone and 6-hydroxychlorzoxazone in rats

1996 • 41 citations

Contribution of Carbohydrate Deficient Transferrin to Gamma Glutamyl Transpeptidase in Evaluating Progress of Patients in Treatment For Alcoholism

1999 • 40 citations

Post-translational inhibition of cytochrome P-450 2E1 expression by chlomethiazole in Fao hepatoma cells.

1999 • 24 citations

Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization

1996 • 16 citations

CYTOCHROME P4502E1, HYDROXYETHYL FREE RADICALS, AND IMMUNE REACTIONS ASSOCIATED WITH ALCOHOLIC LIVER DISEASE

1998 • 10 citations

Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization

1996 • 2 citations