The mitochondrial permeability transition
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Abstract
References (719)
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
1981 • 18,584 citations
Ionic channels of excitable membranes
1985 • 7,199 citations
Hydroperoxide metabolism in mammalian organs.
1979 • 5,821 citations
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
1991 • 4,043 citations
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
1993 • 3,465 citations
Ionic Channels of Excitable Membranes
1985 • 3,014 citations
Single-Channel Recording
1995 • 2,565 citations
Bcl-2 and the regulation of programmed cell death
1994 • 2,346 citations
Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A
1984 • 1,670 citations
Mechanisms by which mitochondria transport calcium
1990 • 1,630 citations
Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins
1989 • 1,414 citations
Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin
1989 • 1,087 citations
A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport
1993 • 939 citations
Cytosolic phosphorylation potential.
1979 • 906 citations
The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.
1982 • 893 citations
Role of Ca2+ in toxic cell killing
1989 • 856 citations
Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.
1988 • 846 citations
ROLE OF REVERSIBLE OXIDATION-REDUCTION OF ENZYME THIOLS-DISULFIDES IN METABOLIC REGULATION
1985 • 840 citations
The Ca2+-induced membrane transition in mitochondria
1979 • 826 citations
The Ca2+-induced membrane transition in mitochondria
1979 • 751 citations
Inhibition of Ca2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase
1990 • 738 citations
Mitochondrial calcium transport: physiological and pathological relevance
1994 • 702 citations
Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria
1989 • 699 citations
Myocardial calcium and magnesium in acute ischemic injury.
1972 • 628 citations
Relationship between configuration, function, and permeability in calcium-treated mitochondria.
1976 • 610 citations
Ca++ Uptake by Rat Kidney Mitochondria and Its Dependence on Respiration and Phosphorylation
1962 • 606 citations
Protection by Cyclosporin A of Ischemia/Reperfusion-Induced Damage in Isolated Rat Hearts
1993 • 571 citations
Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane
1994 • 561 citations
Water Uptake and Extrusion by Mitochondria in Relation to Oxidative Phosphorylation
1962 • 550 citations
The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents
1994 • 527 citations
Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.
1986 • 525 citations
Diamide, a new reagent for the intracellular oxidation of glutathione to the disulfide
1969 • 523 citations
Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow.
1993 • 518 citations
Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes
1989 • 513 citations
Swelling and Lysis of Rat Liver Mitochondria Induced by Ferrous Ions
1963 • 491 citations
Myocardial contractile function during ischemia and hypoxia.
1987 • 486 citations
Coenzyme A and carnitine distribution in normal and ischemic hearts.
1978 • 481 citations
The chemistry of the thiol group.
1974 • 478 citations
A candidate for the permeability pathway of the outer mitochondrial membrane
1979 • 459 citations
Effect of surface active agents on the latent ATPASE of mitochondira
1956 • 455 citations
Fatty acid circuit as a physiological mechanism of uncoupling of oxidative phosphorylation
1991 • 449 citations
Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations.
1992 • 449 citations
The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism
1989 • 443 citations
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization.
1992 • 443 citations
The Ca2+-induced membrane transition in mitochondria
1979 • 442 citations
Stoichiometry of Respiratory Stimulation, Accumulation of Ca++ and Phosphate, and Oxidative Phosphorylation in Rat Liver Mitochondria
1964 • 441 citations
Effect of a transient period of ischemia on myocardial cells. II. Fine structure during the first few minutes of reflow.
1974 • 434 citations
Permeation of hydrophilic solutes through mitochondrial outer membranes: review on mitochondrial porins
1994 • 430 citations
The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+.
1985 • 419 citations
THE CATALYTIC EFFECT OF 2,4-DINITROPHENOL ON ADENOSINETRIPHOSPHATE HYDROLYSIS BY CELL PARTICLES AND SOLUBLE ENZYMES
1953 • 418 citations
EFFECT OF ACTIVE ACCUMULATION OF CALCIUM AND PHOSPHATE IONS ON THE STRUCTURE OF RAT LIVER MITOCHONDRIA
1964 • 374 citations
The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A
1991 • 368 citations
Reversible Inhibition of Mitochondrial Adenosine Diphosphate Phosphorylation by Long Chain Acyl Coenzyme A Esters
1971 • 357 citations
Functions of Glutathione in Liver and Kidney
1978 • 352 citations
Effect of fatty acids on energy coupling processes in mitochondria
1993 • 352 citations
Peptidylproline cis‐trans‐isomerases: immunophilins
1993 • 349 citations
Physiological roles of nicotinamide nucleotide transhydrogenase
1988 • 348 citations
MYOKINASE AND ADENOSINETRIPHOSPHATASE IN OXIDATIVE PHOSPHORYLATION
1951 • 338 citations
Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes
1993 • 337 citations
Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria
1987 • 332 citations
Action of cyclosporine on mitochondrial calcium fluxes
1987 • 329 citations
Control of fatty acid metabolism in ischemic and hypoxic hearts.
1978 • 328 citations
Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria.
1993 • 315 citations
Oxidative stress in mitochondria: Its relationship to cellular Ca2+ homeostasis, cell death, proliferation, and differentiation
1991 • 307 citations
Mitochondrial calcium transport
1980 • 304 citations
Free Radical Damage and its Control
1994 • 297 citations
Voltage gating in the mitochondrial channel, VDAC
1989 • 296 citations
On the involvement of a cyclosporin A sensitive mitochondrial pore in myocardial reperfusion injury
1993 • 295 citations
Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition
1993 • 294 citations
The study of steady-state concentrations of internal solutes of mitochondria by rapid centrifugal transfer to a fixation medium
1957 • 294 citations
Kinetic evidence for a heart mitochondrial pore activated by Ca2+, inorganic phosphate and oxidative stress
1988 • 293 citations
The osmotic behavior and permeability to non-electrolytes of mitochondria
1955 • 293 citations
The ATP/ADP‐antiporter is involved in the uncoupling effect of fatty acids on mitochondria
1989 • 291 citations
Polymer inaccessible volume changes during opening and closing of a voltage-dependent ionic channel
1986 • 289 citations
The relationship between mitochondrial membrane permeability, membrane potential, and the retention of Ca2+ by mitochondria.
1980 • 288 citations
Oxygen Radicals in Chemistry and Biology
1985 • 285 citations
THE EFFECT OF THYROXINE AND OTHER SUBSTANCES ON THE SWELLING OF ISOLATED RAT LIVER MITOCHONDRIA
1956 • 278 citations
Membrane protein oligomeric structure and transport function
1981 • 277 citations
INACTIVATION OF OXIDATIVE AND PHOSPHORYLATIVE SYSTEMS IN MITOCHONDRIA BY PREINCUBATION WITH PHOSPHATE AND OTHER IONS
1955 • 277 citations
Cyclosporin A, the cyclophilin class of peptidylprolyl isomerases, and blockade of T cell signal transduction.
1992 • 276 citations
An Endogenous Uncoupling and Swelling Agent in Liver Mitochondria and Its Enzymic Formation
1959 • 275 citations
Hydrolysis of phospholipids and glycerides by rat-liver preparations
1967 • 273 citations
Selectivity Changes in Site-Directed Mutants of the VDAC Ion Channel: Structural Implications
1990 • 269 citations
Acyl-CoA inhibition of adenine nucleotide translocation in ischemic myocardium
1975 • 267 citations
The mitochondrial megachannel is the permeability transition pore
1992 • 262 citations
Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A
1991 • 261 citations
Cyclosporin A, FK506 and rapamycin: more than just immunosuppression
1993 • 259 citations
Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondrial damage.
1986 • 258 citations
Oxidation in the NADP system and release of GSSG from hemoglobin‐free perfused rat liver during peroxidatic oxidation of glutathione by hydroperoxides
1972 • 257 citations
The effect of calcium on the respiratory and phosphorylative activities of heart-muscle sarcosomes
1953 • 253 citations
Alloxan-induced diabetes—evidence for hydroxyl radical as a cytotoxic intermediate
1976 • 249 citations
Changes in tissue levels of carnitine and other metabolites during myocardial ischemia and anoxia
1978 • 249 citations
Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.
1993 • 239 citations
Swelling and contraction of the mitochondrial matrix. I. A structural interpretation of the relationship between light scattering and matrix volume.
1985 • 237 citations
Molecular aspects of the adenine nucleotide carrier from mitochondria
1989 • 235 citations
Modulation of the mitochondrial megachannel by divalent cations and protons.
1992 • 232 citations
The Steady State Maintenance of Accumulated Ca++ in Rat Liver Mitochondria
1965 • 232 citations
Patch-clamping of the inner mitochondrial membrane reveals a voltage-dependent ion channel
1987 • 232 citations
S-Thiolation of Individual Human Neutrophil Proteins Including Actin by Stimulation of the Respiratory Burst: Evidence against a Role for Glutathione Disulfide
1994 • 228 citations
Formation and disappearance of an endogenous uncoupling factor during swelling and contraction of mitochondria
1961 • 227 citations
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. II. The minimal requirements for pore induction underscore a key role for transmembrane electrical potential, matrix pH, and matrix Ca2+.
1993 • 225 citations
Reversal of Various Types of Mitochondrial Swelling by Adenosine Triphosphate
1959 • 224 citations
The inner mitochondrial membrane contains ion‐conducting channels similar to those found in bacteria
1989 • 224 citations
Reduced Triphosphopyridine Nucleotide Oxidase-catalyzed Alterations of Membrane Phospholipids
1971 • 223 citations
The role of glutathione in the retention of Ca2+ by liver mitochondria.
1984 • 223 citations
Imaging in five dimensions: time-dependent membrane potentials in individual mitochondria
1993 • 221 citations
Hydroperoxide-induced loss of pyridine nucleotides and release of calcium from rat liver mitochondria.
1980 • 220 citations
Characterization of translocation contact sites involved in the import of mitochondrial proteins.
1987 • 219 citations
Pro‐oxidants and mitochondrial Ca2+: their relationship to apoptosis and oncogenesis
1993 • 218 citations
Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin
1991 • 217 citations
Mitochondrial outer membrane contains a protein producing nonspecific diffusion channels.
1980 • 214 citations
The mitochondrial transport protein superfamily
1993 • 213 citations
The phosphorylation potential generated by respiring mitochondria
1973 • 212 citations
Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A
1994 • 208 citations
Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro
1979 • 206 citations
Properties of glutathione release observed during reduction of organic hydroperoxide, demethylation of aminopyrine and oxidation of some substances in perfused rat liver, and their implications for the physiological function of catalase
1977 • 206 citations
Mitochondrial channel activity studied by patch-clamping mitoplasts
1989 • 206 citations
A third ADP/ATP translocator gene in yeast.
1990 • 205 citations
Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane.
1986 • 202 citations
Transport Proteins in Bacteria: Common Themes in Their Design
1992 • 200 citations
NADH regulates the gating of VDAC, the mitochondrial outer membrane channel.
1994 • 200 citations
NADH- and NADPH-dependent lipid peroxidation in bovine heart submitochondrial particles. Dependence on the rate of electron flow in the respiratory chain and an antioxidant role of ubiquinol
1980 • 200 citations
Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. One gene codes for both the cytosolic and mitochondrial forms.
1988 • 199 citations
Membrane protein thiol cross-linking associated with the permeabilization of the inner mitochondrial membrane by Ca2+ plus prooxidants.
1990 • 198 citations
Molecular cloning of a cDNA for a human ADP/ATP carrier which is growth-regulated.
1987 • 198 citations
Channel-Like Function of the Na,K Pump Probed at Microsecond Resolution in Giant Membrane Patches
1994 • 197 citations
The action of paraquat and diquat on the respiration of liver cell fractions
1968 • 197 citations
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. I. Evidence for two separate Me2+ binding sites with opposing effects on the pore open probability.
1993 • 191 citations
Reversal of ischemic mitochondrial dysfunction.
1981 • 191 citations
Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin
1992 • 189 citations
Intramitochondrial phospholipase activity and the effects of Ca2+ plus N-ethylmaleimide on mitochondrial function.
1979 • 189 citations
Respiration-dependent accumulation of inorganic phosphate and Ca++ by rat liver mitochondria
1963 • 187 citations
The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms.
1991 • 187 citations
Contact sites between mitochondrial envelope membranes. Structure and function in energy- and protein-transfer
1991 • 187 citations
Involvement of the ADPATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: Importance of the orientation of the nucleotide binding site
1988 • 186 citations
The inhibition of adenine nucleotide translocase activity by oleoyl CoA and its reversal in rat liver mitochondria
1971 • 185 citations
Lipid peroxidation in mitochondria
1988 • 185 citations
Biochemistry of Sulfur
1986 • 184 citations
Regulated release of Ca2+ from respiring mitochondria by Ca2+/2H+ antiport.
1979 • 182 citations
STRUCTURE AND MODE OF ACTION OF A VOLTAGE DEPENDENT ANION‐SELECTIVE CHANNEL (VDAC) LOCATED IN THE OUTER MITOCHONDRIAL MEMBRANE DEPENDENT ANION‐SELECTIVE CHANNEL (VDAC)*
1980 • 182 citations
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation
1993 • 181 citations
The mode of action of thyroxin
1951 • 178 citations
Differences between the ATP/ADP Ratios in the Mitochondrial Matrix and in the Extramitochondrial Space
1972 • 177 citations
Energy-linked nicotinamide nucleotide transhydrogenases
1977 • 176 citations
Some observations on the photometric estimation of mitochondrial volume
1958 • 175 citations
Phosphorylation status of liver by 31P-n.m.r. spectroscopy, and its implications for metabolic control. A comparison of 31P-n.m.r. spectroscopy (in vivo and in vitro) with chemical and enzymic determinations of ATP, ADP and Pi
1985 • 174 citations
Mitochondrial Generation of Oxygen Radicals During Reoxygenation of Ischemic Tissues
1991 • 174 citations
The reversible Ca2+-induced permeabilization of rat liver mitochondria
1986 • 174 citations
Pharmacology of cyclosporine (sandimmune). IV. Pharmacological properties in vivo.
1990 • 174 citations
Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. Isolation and analysis of AAC2.
1988 • 173 citations
The mitochondrial permeability transition pore may comprise VDAC molecules
1993 • 172 citations
Reversible Inhibition of Adenine Nucleotide Translocation by Long Chain Fatty Acyl Coenzyme A Esters in Liver Mitochondria of Diabetic and Hibernating Animals
1972 • 172 citations
A heart mitochondrial Ca2+-dependent pore of possible relevance to re-perfusion-induced injury. Evidence that ADP facilitates pore interconversion between the closed and open states
1990 • 168 citations
Ca2+ release from mitochondria induced by prooxidants
1988 • 166 citations
Superoxide dismutase is a prophylactic against alloxan diabetes
1981 • 166 citations
The mitochondrial permeability transition pore may comprise VDAC molecules
1993 • 166 citations
Integration of Mitochondrial Function
1988 • 165 citations
Reversal of Thyroxine-induced Swelling of Rat Liver Mitochondria by Adenosine Triphosphate
1959 • 165 citations
Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins.
1989 • 165 citations
CALCIUM ION ACCUMULATION AND VOLUME CHANGES OF ISOLATED LIVER MITOCHONDRIA. CALCIUM ION-INDUCED SWELLING
1965 • 164 citations
Molecular cloning and sequencing of cDNA for yeast porin, an outer mitochondrial membrane protein: a search for targeting signal in the primary structure.
1985 • 164 citations
Mitochondrial porin of Neurospora crassa: cDNA cloning, in vitro expression and import into mitochondria.
1987 • 163 citations
Structure of the outer mitochondrial membrane: ordered arrays of porelike subunits in outer-membrane fractions from neurospora crassa mitochondria
1982 • 162 citations
The regulation of brain mitochondrial calcium-ion transport. The role of ATP in the discrimination between kinetic and membrane-potential-dependent calcium-ion efflux mechanisms
1980 • 161 citations
THE ASSAY OF ANIMAL TISSUES FOR RESPIRATORY ENZYMES
1943 • 161 citations
Irreversible myocardial injury in anoxic perfused rat hearts.
1975 • 160 citations
Effects of phospholipase A2 inhibitors on ruthenium red-induced Ca2+ release from mitochondria.
1985 • 160 citations
The metabolism of menadione impairs the ability of rat liver mitochondria to take up and retain calcium.
1982 • 159 citations
The peripheral‐type benzodiazepine receptor: a protein of mitochondrial outer membranes utilizing porphyrins as endogenous ligands
1987 • 159 citations
BIOCHEMICAL STRUCTURE OF MITOCHONDRIA
1955 • 159 citations
Allosteric inhibition of the Ca2+-activated hydrophilic channel of the mitochondrial inner membrane by nucleotides
1980 • 157 citations
Structural and functional abnormalities in mitochondria isolated from ischemic dog myocardium.
1969 • 156 citations
The Effect of Thiols and Disulfides on Water Uptake and Extrusion by Rat Liver Mitochondria
1962 • 155 citations
Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion
1991 • 151 citations
Effects of Trialkyltin and Triphenyltin Copounds on Mitochondrial Respiration
1970 • 151 citations
Oxidative damage to mitochondria is mediated by the Ca2+-dependent inner-membrane permeability transition
1993 • 151 citations
The mitochondrial outer membrane channel, VDAC, is regulated by a synthetic polyanion
1987 • 150 citations
Calcium-dependent opening of a non-specific pore in the mitochondrial inner membrane is inhibited at pH values below 7. Implications for the protective effect of low pH against chemical and hypoxic cell damage
1991 • 149 citations
Toward the molecular structure of the mitochondrial channel, VDAC
1992 • 149 citations
Oxygen radicals in chemistry and biology
1985 • 149 citations
Permeability of Isolated Rat Heart Sarcosomes
1952 • 148 citations
The Swelling of Rat Liver Mitochondria by Thyroxine and its Reversal
1959 • 148 citations
The cationically selective state of the mitochondrial outer membrane pore: a study with intact mitochondria and reconstituted mitochondrial porin
1990 • 147 citations
Electrophysiology of the inner mitochondrial membrane
1994 • 147 citations
Metabolic and Structural States of Mitochondria
1960 • 147 citations
The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A.
1992 • 146 citations
Effect of nicotinamide adenine dinucleotide on the membrane-associated reduced nicotinamide adenine dinucleotide oxidase of Mycobacterium phlei.
1975 • 145 citations
A Hypothesis for the Role of Dithiol‐Disulfide Interchange in Solute Transport and Energy‐Transducing Processes
1982 • 143 citations
Cation binding to submitochondrial particles
1968 • 143 citations
Carboxyatractylate inhibits the uncoupling effect of free fatty acids
1988 • 143 citations
LATENT ADENOSINETRIPHOSPHATASE ACTIVITY IN RESTING RAT LIVER MITOCHONDRIA
1953 • 142 citations
DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase
1989 • 142 citations
Damage to rat liver mitochondria promoted by δ-aminolevulinic acid-generated reactive oxygen species: connections with acute intermittent porphyria and lead-poisoning
1991 • 141 citations
Movements of water and ions in mitochondria
1956 • 141 citations
Effects of local anaesthetics on phospholipases
1976 • 140 citations
Properties of the inner membrane anion channel in intact mitochondria
1992 • 139 citations
METABOLIC EFFECTS OF THYROID HORMONES IN VITRO
1953 • 139 citations
The Participation of Reactive Oxygen Species and Protein Thiols in the Mechanism of Mitochondrial Inner Membrane Permeabilization by Calcium plus Prooxidants
1993 • 139 citations
Studies on the Mechanism of Swelling, Lysis, and Distintegration of Isolated Liver Mitochondria Exposed to Mixtures of Oxidized and Reduced Glutathione
1964 • 139 citations
Intracellular pH and Ca2+ homeostasis in the pH paradox of reperfusion injury to neonatal rat cardiac myocytes
1993 • 138 citations
Studies on the Mechanism of Ascorbate-induced Swelling and Lysis of Isolated Liver Mitochondria
1964 • 135 citations
KURZMITTEILUNG
1982 • 135 citations
Pyridine‐nucleotide oxidation, Ca2+ cycling and membrane damage during tert‐butyl hydroperoxide metabolism by rat‐liver mitochondria
1984 • 135 citations
Determination of the Proton Electrochemical Gradient across Biological Membranes
1984 • 134 citations
Potentiation of oxidative cell injury in hepatocytes which have accumulated Ca2+.
1984 • 133 citations
Changes in freeze-fractured mitochondrial membranes correlated to their energetic state
1983 • 132 citations
ESTERIFICATION OF INORGANIC PHOSPHATE COUPLED TO ELECTRON TRANSPORT BETWEEN DIHYDRODIPHOSPHOPYRIDINE NUCLEOTIDE AND OXYGEN. II
1949 • 132 citations
Uptake of Adenine Nucleotides by Respiring Mitochondria during Active Accumulation of Ca++ and Phosphate
1965 • 131 citations
Protection by acidotic pH against anoxia/reoxygenation injury to rat neonatal cardiac myocytes
1991 • 131 citations
Role of superoxide radicals in the lipid peroxidation of intracellular membranes
1975 • 129 citations
Differentiation of phospholipases A in mitochondria and lysosomes of rat liver
1969 • 129 citations
Calcium and pyridine nucleotide interaction in mitochondrial membranes
1972 • 128 citations
Nucleotide sequence of the cloned mRNA and gene of the ADP/ATP carrier from Neurospora crassa.
1984 • 127 citations
Porin pores of mitochondrial outer membranes from high and low eukaryotic cells: biochemical and biophysical characterization
1987 • 127 citations
Reoxygenation-dependent decrease in mitochondrial NADH:CoQ reductase (Complex I) activity in the hypoxic/reoxygenated rat heart
1991 • 126 citations
The mitochondrial aspartate/glutamate and ADP/ATP carrier switch from obligate counterexchange to unidirectional transport after modification by SH-reagents
1990 • 126 citations
Evidence for the existence of an inner membrane anion channel in mitochondria
1986 • 126 citations
Sudden deaths of babies.
1976 • 125 citations
Mechanism of phospholipid peroxidation induced by ferric ion-ADP-adriamycin-co-ordination complex
1982 • 125 citations
An appraisal of the functional significance of the inhibitory effect of long chain acyl‐CoAs on mitochondrial transports
1974 • 125 citations
The Role of Phosphate in the Regulation of the Independent Calcium‐Efflux Pathway of Liver Mitochondria
1982 • 124 citations
Characterization of cysteine residues of mitochondrial ADP/ATP carrier with the SH-reagents eosin 5-maleimide and N-ethylmaleimide.
1993 • 124 citations
Spermine Inhibition of the Permeability Transition of Isolated Rat Liver Mitochondria: An Investigation of Mechanism
1993 • 124 citations
Detection of hydroxyl radical in the mitochondria of ischemic-reperfused myocardium by trapping with salicylate
1989 • 123 citations
Channels in Mitochondrial Membranes: Knowns, Unknowns, and Prospects for the Future
1993 • 123 citations
Cyclosporin A-sensitive and insensitive mechanisms produce the permeability transition in mitochondria
1989 • 122 citations
A Role of Mitochondrial Glutathione Peroxidase in Modulating Mitochondrial Oxidations in Liver
1978 • 122 citations
Possible role of non-bilayer lipids in the structure of mitochondria. A freeze-fracture electron microscopy study
1982 • 121 citations
Molecular genetics of the VDAC ion channel: Structural model and sequence analysis
1987 • 121 citations
The functional compartmentation of mitochondrial hexokinase
1974 • 120 citations
THE ASSAY OF ANIMAL TISSUES FOR RESPIRATORY ENZYMES
1947 • 119 citations
Increase in hepatic mixed disulphide and glutathione disulphide levels elicited by paraquat
1982 • 118 citations
TRANSPORT AND ACCUMULATION OF CALCIUM IN MITOCHONDRIA
1978 • 117 citations
Reversal of ischemic mitochondrial dysfunction.
1979 • 117 citations
ION-INDUCED ULTRASTRUCTURAL TRANSFORMATIONS IN ISOLATED MITOCHONDRIA
1969 • 115 citations
Spectrophotometric Studies of Oxidative Phosphorylation
1956 • 115 citations
Studies on the Mechanism by Which Anaerobiosis Prevents Swelling of Mitochondria in Vitro: Effect of Electron Transport Chain Inhibitors
1959 • 115 citations
Subcellular characteristics of phospholipase A2 activity in the rat kidney. Enhanced cytosolic, mitochondrial, and microsomal phospholipase A2 enzymatic activity after renal ischemia and reperfusion.
1991 • 115 citations
Swelling and contraction of the mitochondrial matrix. II. Quantitative application of the light scattering technique to solute transport across the inner membrane.
1985 • 114 citations
Phenylarsine oxide induces the cyclosporin A-sensitive membrane permeability transition in rat liver mitochondria
1991 • 114 citations
Chemical structure and biochemical significance of lysolecithins from rat liver
1965 • 113 citations
The action of thyroxine on mitochondria and oxidative phosphorylation
1955 • 113 citations
Mitochondrial Swelling Induced by Glutathione
1959 • 113 citations
The effect of local anesthetics on the hydrolysis of free and membrane-bound phospholipids catalyzed by various phospholipases
1972 • 112 citations
Participation of an Intermediate of Oxidative Phosphorylation in Ion Accumulation by Mitochondria
1963 • 112 citations
Regulation of the mitochondrial adenine nucleotide pool size in liver: mechanism and metabolic role
1988 • 112 citations
Mitochondrial boundary membrane contact sites in brain: Points of hexokinase and creatine kinase location, and control of Ca2+ transport
1988 • 111 citations
The permeability of isolated rat-liver mitochondria to sucrose, sodium chloride and potassium chloride at 0°
1958 • 111 citations
Magnesium-Ion Modulates the Sensitivity of the Mitochondrial Permeability Transition Pore to Cyclosporine-A and ADP
1994 • 110 citations
The Energy‐State of Mitochondria during the Transport of Ca2+
1980 • 110 citations
The cell cycle block and lysis of an activated T cell hybridoma are distinct processes with different Ca2+ requirements and sensitivity to cyclosporine A.
1989 • 110 citations
Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo
1981 • 109 citations
Changes in the water, sodium and potassium content of rat-liver mitochondria during metabolism
1953 • 109 citations
Increased permeability of mitochondria during Ca2+ release induced by t-butyl hydroperoxide or oxalacetate. the effect of ruthenium red.
1982 • 109 citations
Chemical, immunological, enzymatic, and genetic approaches to studying the arrangement of the peptide chain of the ADP/ATP carrier in the mitochondrial membrane
1993 • 108 citations
Mitochondrial swelling and uncoupling of oxidative phosphorylation by lysosomes
1967 • 107 citations
Mitochondrial calcium release as induced by Hg2+.
1988 • 106 citations
The equivalent pore radius of intact and damaged mitochondria and the mechanism of active shrinkage
1972 • 106 citations
The presence of two classes of high‐affinity cyclosporin A binding sites in mitochondria
1990 • 104 citations
Evidence for the involvement of dithiol groups in mitochondrial calcium transport: Studies with cadmium
1985 • 102 citations
Uptake and Release of Bivalent Cations in Mitochondria1 1Dedicated to Eva.
1980 • 101 citations
INTRAMITOCHONDRIAL REGULATION OF OXIDATIVE RATE
1953 • 101 citations
Menadione-(2-methyl-1,4-naphthoquinone) dependent enzymic redox cycling and calcium release by mitochondria
1986 • 100 citations
Pore-like and carrier-like properties of the mitochondrial aspartate/glutamate carrier after modification by SH-reagents: evidence for a preformed channel as a structural requirement of carrier-mediated transport
1990 • 100 citations
Studies on mitochondria:
1952 • 99 citations
Partial purification and characterization of the phospholipase A2 from rat liver mitochondria
1971 • 99 citations
Uncoupling of oxidative phosphorylation and inhibition of ATPPi exchange by a substance from insect mitochondria
1960 • 99 citations
Phospholipase A activity of rat-liver mitochondria
1965 • 98 citations
Studies on mitochondria: I. The association of cyclophorase with mitochondria
1950 • 97 citations
Regulation of the mitochondrial matrix volume in vivo and in vitro. The role of calcium
1986 • 97 citations
Modulation of inner mitochondrial membrane channel activity
1992 • 97 citations
Stimulation of mitochondrial calcium ion efflux by thiol-specific reagents and by thyroxine. The relationship to adenosine diphosphate retention and to mitochondrial permeability
1979 • 96 citations
Peripheral-type benzodiazepine receptors
1993 • 96 citations
Cyclosporin A protects hepatocytes subjected to high Ca2+ and oxidative stress
1992 • 96 citations
Cyclosporine augments receptor-mediated cellular Ca2+ fluxes in isolated hepatocytes.
1985 • 95 citations
The control of Ca2+ release from heart mitochondria.
1981 • 95 citations
Dialectics in carrier research: The ADP/ATP carrier and the uncoupling protein
1993 • 95 citations
The effect of antimycin A on mouse liver inner mitochondrial membrane channel activity.
1992 • 95 citations
Permeability of inner mitochondrial membrane and oxidative stress
1988 • 94 citations
Maintenance of Energy-Linked Functions in Rat-Liver Mitochondria Aged in the Presence of Nupercaine
1972 • 94 citations
The nature of the calcium ion efflux induced in rat liver mitochondria by the oxidation of endogenous nicotinamide nucleotides
1980 • 94 citations
On the relationship between Ca2+ efflux and membrane damage during t‐butylhydroperoxide metabolism by liver mitochondria
1983 • 93 citations
The mitochondrial permeability transition. Interactions of spermine, ADP, and inorganic phosphate.
1994 • 93 citations
Demonstration of the relation between the adenine nucleotide carrier and the structural changes of mitochondria as induced by adenosine 5'-diphosphate
1974 • 92 citations
Inhibition of permeability-dependent Ca2+ release from mitochondria by N-acylethanolamines, a class of lipids synthesized in ischemic heart tissue.
1982 • 91 citations
Effects of Oligomycin on Respiration and Swelling of Isolated Liver Mitochondria
1961 • 90 citations
CYCLOPHILIN, A PRIMARY MOLECULAR TARGET FOR CYCLOSPORINE
1988 • 90 citations
MITOCHROME
1957 • 89 citations
Stable enhancement of calcium retention in mitochondria isolated from rat liver after the administration of glucagon to the intact animal
1978 • 89 citations
The proton-translocating nicotinamide–adenine dinucleotide (phosphate) transhydrogenase of rat liver mitochondria
1973 • 89 citations
Oxidative phosphorylation in insect sarcosomes
1954 • 89 citations
Partial inhibition by cyclosporin A of the swelling of liver mitochondria in vivo and in vitro induced by sub-micromolar [Ca2+], but not by butyrate. Evidence for two distinct swelling mechanisms
1990 • 88 citations
ADP/ATP translocator is essential only for anaerobic growth of yeast Saccharomyces cerevisiae
1991 • 88 citations
The 35 kDa DCCD-binding protein from pig heart mitochondria is the mitochondrial porin
1985 • 87 citations
Calcium modulation of mitochondrial inner membrane channel activity
1991 • 87 citations
Ischemia: from acidosis to oxidation
1993 • 87 citations
Ischemia/Reperfusion-Induced Injury of Forebrain Mitochondria and Protection by Ascorbate
1993 • 87 citations
Phospholipase A activity of rat-liver mitochondria
1965 • 86 citations
On the involvement of a mitochondrial pore in reperfusion injury
1993 • 86 citations
Mitochondrial calcium release induced by prooxidants
1993 • 86 citations
Isolation and cloning of a voltage-dependent anion channel-like Mr 36,000 polypeptide from mammalian brain.
1992 • 86 citations
Location and regulation of octameric mitochondrial creatine kinase in the contact sites
1991 • 85 citations
Evidence that spermine, spermidine, and putrescine are transported electrophoretically in mitochondria by a specific polyamine uniporter.
1992 • 85 citations
Effect of pH and Ca2+ on the retention of Ca2+ by rat liver mitochondria
1978 • 85 citations
Reconstitution of the beef heart and rat liver mitochondrial K+/H+ (Na+/H+) antiporter. Quantitation of K+ transport with the novel fluorescent probe, PBFI.
1990 • 83 citations
Destruction of Phosphilipids and Respiratory‐Chain Activity in Pig=Heart Submitochondrial Particles Induced by an Adriamycin‐Iron Complex
1983 • 83 citations
Formation of lysophosphatidyl ethanolamines in cell fractions of rat liver
1966 • 83 citations
Mitochondrial coupling factor B
1982 • 82 citations
Phospholipase activity in rat liver mitochondria studied by the use of endogenous substrates
1966 • 81 citations
EGTA inhibits reverse uniport-dependent Ca2+ release from uncoupled mitochondria. Possible regulation of the Ca2+ uniporter by a Ca2+ binding site on the cytoplasmic side of the inner membrane.
1988 • 81 citations
Electrophysiological characterization of contact sites in brain mitochondria.
1990 • 79 citations
Inhibition of the mitochondrial adenine nucleotide transport system by oleyl CoA
1972 • 79 citations
Efflux of Adenine Nucleotides from Rat Liver Mitochondria
1968 • 79 citations
Relations between extramitochondrial and intramitochondrial adenine nucleotide systems
1981 • 78 citations
Mechanism and regulation of the mitochondrial ATP-Mg/Pi carrier
1993 • 78 citations
Manganese, a Co-factor of Oxidative Phosphorylation
1954 • 77 citations
Oxidation-reduction state of rat liver mitochondria and the action of thyroxine
1957 • 77 citations
Metabolic and Structural States of Mitochondria
1961 • 77 citations
Effect of SH reagents on atractyloside binding to mitochondria and ADP translocation. Potentiation by ADP and its prevention by uncoupler FCCP
1972 • 77 citations
The stability of oxidative and phosphorylative systems in mitochondria under anaerobic conditions
1956 • 76 citations
Myocardial and Skeletal Muscle Bioenergetics
1986 • 76 citations
The mitochondrial benzodiazepine receptor: Evidence for association with the voltage-dependent anion channel (VDAC)
1992 • 76 citations
In vitro alteration of the size of the liver mitochondrial adenine nucleotide pool: Correlation with respiratory functions
1980 • 76 citations
Isolation of rat liver mitochondrial membrane fractions and localization of the phospholipase A
1969 • 76 citations
Proton electrochemical potential in steady state rat liver mitochondria
1977 • 75 citations
Reduced Triphosphopyridine Nucleotide Oxidase-catalyzed Alterations of Membrane Phospholipids
1972 • 75 citations
Correlated Effluxes of Adenine Nucleotides, Mg2+ and Ca2+ Induced in Rat‐Liver Mitochondria by External Ca2+ and Phosphate
1981 • 75 citations
ATP Prevents both Hydroperoxide‐Induced Hydrolysis of Pyridine Nucleotides and Release of Calcium in Rat Liver Mitochondria
1981 • 75 citations
The mitochondrial inner membrane anion channel. Regulation by divalent cations and protons.
1987 • 74 citations
Protein S-Thiolation in Hepatocytes Stimulated by t-Butyl Hydroperoxide, Menadione, and Neutrophils
1994 • 74 citations
The stabilizing effect of spermine and related amines on mitochondria and protoplasts
1960 • 73 citations
Oxidative Damage of Mitochondria Induced by Fe(II)Citrate Is Potentiated by Ca2+ and Includes Lipid Peroxidation and Alterations in Membrane Proteins
1994 • 73 citations
Pharmacology of cyclosporine (sandimmune). V. Pharmacological effects on immune function: in vitro studies.
1990 • 73 citations
The formation of mixed disulphides in rat lung following paraquat administration Correlation with changes in intermediary metabolism
1982 • 73 citations
Isolation of the ADP/ATP Translocator from Beef Heart Mitochondria as the Bongkrekate‐Protein Complex
1978 • 73 citations
Effect of Thyroxine on the Swelling of Mitochondria isolated from Various Tissues of the Rat
1956 • 73 citations
Effects of atractyloside and palmitoyl coenzyme A on calcium transport in cardiac mitochondria
1977 • 73 citations
Characterization of porphyrin interactions with peripheral type benzodiazepine receptors.
1988 • 72 citations
Regulation of Ca2+ Efflux from Kidney and Liver Mitochondria by Unsaturated Fatty Acids and Na+ Ions
1979 • 72 citations
N-acetyl-p-benzoquinone imine induces Ca2+ release from mitochondria by stimulating pyridine nucleotide hydrolysis.
1992 • 72 citations
On the inter-relationship between glucagon action, the oxidation-reduction state of pyridine nucleotides, and calcium retention by rat liver mitochondria.
1980 • 71 citations
Reversible inhibition of adenine nucleotide translocation by long chain acyl-CoA esters in bovine heart mitochondria and inverted submitochondrial particles. Comparison with atractylate and bongkrekic acid.
1977 • 71 citations
Selectivity for Omega-Receptor Subtypes as a Strategy for the Development of Anxiolytic Drugs
1990 • 71 citations
Release of mitochondrial matrix proteins through a Ca2+-requiring, cyclosporin-sensitive pathway
1989 • 71 citations
Dependence of Mitochondrial Swelling on Oxidizable Substrates
1958 • 69 citations
Functional principles of solute transport systems: concepts and perspectives
1994 • 69 citations
The uncoupling of oxidative phosphorylation in rat-liver mitochondria by thyroxine, triiodothyronine and related substances
1955 • 69 citations
Studies on the acylation of lysolecithin by rat brain
1964 • 69 citations
Mechanism of alloxan-induced calcium release from rat liver mitochondria.
1985 • 69 citations
The effect of phosphoenolypyruvate on calcium transport by mitochondria
1973 • 69 citations
CALCIUM ION ACCUMULATION AND VOLUME CHANGES OF ISOLATED LIVER MITOCHONDRIA. REVERSAL OF CALCIUM ION-INDUCED SWELLING
1965 • 69 citations
Inhibition of Na+/H+ exchange preserves viability, restores mechanical function, and prevents the pH paradox in reperfusion injury to rat neonatal myocytes
1993 • 68 citations
L-Propionyl-carnitine protection of mitochondria in ischemic rat hearts
1989 • 68 citations
Liver mitochondrial pyrophosphate concentration is increased by Ca2+ and regulates the intramitochondrial volume and adenine nucleotide content
1987 • 68 citations
Studies on the Respiratory Chain-linked Nicotinamide Adenine Dinucleotide Dehydrogenase
1971 • 67 citations
Changes in intracellular free calcium concentration during long exposures to simulated ischemia in isolated mammalian ventricular muscle.
1992 • 67 citations
The participation of NADP, the transmembrane potential and the energy-linked NAD(P) transhydrogenase in the process of Ca2+ efflux from rat liver mitochondria
1987 • 66 citations
The effect of superoxide generation on the ability of mitochondria to take up and retain Ca2+
1982 • 66 citations
Transmembrane arrangement of mitochondrial porin or voltage-dependent anion channel (VDAC)
1992 • 66 citations
Relationships between the NAD(P) redox state, fatty acid oxidation, and inner membrane permeability in rat liver mitochondria
1989 • 65 citations
Surface topography and molecular stoichiometry of the mitochondrial channel, VDAC, in crystalline arrays*1
1991 • 65 citations
‘Pore’ formation is not required for the hydroperoxide-induced Ca2+ release from rat liver mitochondria
1992 • 65 citations
The hydroperoxide‐induced release of mitochondrial calcium occurs via a distinct pathway and leaves mitochondria intact
1982 • 65 citations
FK 506 ameliorates the hepatic injury associated with ischemia and reperfusion in rats
1991 • 65 citations
Calcium-dependent mitochondrial oxidative damage promoted by 5-aminolevulinic acid
1992 • 65 citations
Adenine nucleotide translocase as a site of regulation by ADP of the rat liver mitochondria permeability to H+ and K+ lons
1980 • 65 citations
Relationships between Ca2+ release, Ca2+ cycling, and Ca2+-mediated permeability changes in mitochondria.
1985 • 65 citations
Mono(ADP-ribosylation) in rat liver mitochondria
1988 • 65 citations
Mitochondrial lipid peroxidation by cumene hydroperoxide and its prevention by succinate
1982 • 64 citations
Selective Activation of the Sodium-Independent, Cyclosporine A-Sensitive Calcium Pore of Cardiac Mitochondria by Doxorubicin
1993 • 64 citations
Mitochondrial energy production and cation control in myocardial ischaemia and reperfusion
1993 • 64 citations
Pore formation by the mitochondrial porin of rat brain in lipid bilayer membranes
1986 • 64 citations
Localization of phospholipase A2 in outer membrane of mitochondria
1968 • 63 citations
Incorporation in lipid bilayers of a large conductance cationic channel from mitochondrial membranes.
1988 • 63 citations
Structure-function studies of adenine nucleotide transport in mitochondria. I. Construction and genetic analysis of yeast mutants encoding the ADP/ATP carrier protein of mitochondria.
1990 • 63 citations
ADP-ribosyl transferase and NAD glycohydrolase activities in rat liver mitochondria
1987 • 63 citations
Ruthenium red sensitive and insensitive calcium transport in rat liver and Ehrlich ascites tumor cell mitochondria
1978 • 62 citations
The uptake and release of calcium by heart mitochondria
1977 • 62 citations
Crucial role of sulfhydryl groups in the mitochondrial inner membrane structure.
1985 • 62 citations
Effects of N-ethylmaleimide on the limited uptake of Ca2+, Mn2+, and Sr2+ by rat liver mitochondria.
1978 • 62 citations
Relation of mitochondrial phospholipase A activity to mitochondrial swelling
1969 • 62 citations
Induction of swelling of liver mitochondria by fatty acids of various chain length
1963 • 62 citations
The role of superoxide in xanthine oxidase-induced autooxidation of linoleic acid.
1982 • 62 citations
Mechanisms of reoxygenation injury in cultured ventricular myocytes.
1991 • 62 citations
Adenine nucleotide transport in sonic submitochondrial particles. Kinetic properties and binding of specific inhibitors
1977 • 61 citations
Organization of mitochondrial DPN-linked systems
1956 • 61 citations
Changes in Mitochondrial Matrix Free Calcium in Perfused Rat Hearts Subjected to Hypoxia-Reoxygenation
1993 • 61 citations
Hydrodynamic properties of porin isolated from outer membranes of rat liver mitochondria
1983 • 60 citations
Regulation of Ca2+ transport in brain mitochondria. I. The mechanism of spermine enhancement of Ca2+ uptake and retention
1990 • 60 citations
Pharmacology of cyclosporine. VI. Cellular activation: regulation of intracellular events by cyclosporine.
1990 • 60 citations
Cyclosporine a inhibits mitochondrial pyridine nucleotide hydrolysis and calcium release
1990 • 60 citations
Possible participation of membrane thiol groups on the mechanism of NAD(P)+-stimulated Ca2+ efflux from mitochondria
1984 • 60 citations
THE BENEFICIAL EFFECT OF CYCLOSPORINE ON LIVER ISCHEMIA IN RATS
1989 • 60 citations
Pyridine nucleotides in rat-liver mitochondria I. The demonstration of a new form of diphosphopyridine nucleotide and of triphosphopyridine nucleotide
1960 • 59 citations
Reincorporation of Diphosphopyridine Nucleotide into Mitochondrial Enzyme Systems
1959 • 59 citations
Retention of Ca2+ by rat liver and rat heart mitochondria: Effect of phosphate, Mg2+, and NAD(P) redox state
1980 • 59 citations
Phenothiazines and related compounds disrupt mitochondrial energy production by a calmodulin-independent reaction
1981 • 59 citations
Chapter 4 Anion Channels in the Mitochondrial Outer Membrane
1994 • 59 citations
Patch clamping the outer mitochondrial membrane
1987 • 59 citations
Inhibition by spermine of the inner membrane permeability transition of isolated rat heart mitochondria
1992 • 59 citations
Blockade of a mitochondrial cationic channel by an addressing peptide: An electrophysiological study
1989 • 58 citations
Patch clamping VDAC in liposomes containing whole mitochondrial membranes
1991 • 58 citations
Organization of mitochondrial DPN-linked systems
1956 • 58 citations
Antibiotics as Tools for Metabolic Studies. III. Effects of Oligomycin and Aurovertin on the Swelling and Contraction Processes of Mitochondria*
1964 • 57 citations
Induction of swelling of liver mitochondria by fatty acids of various chain length
1963 • 57 citations
Localization of the ATP/ADP translocator in the inner membrane and regulation of contact sites between mitochondrial envelope membranes by ADP. A study on freeze-fractured isolated liver mitochondria
1991 • 57 citations
Cross-linking analysis of yeast mitochondrial outer membrane
1986 • 57 citations
Effects of thyroid hormones in vitro on tissue respiration, oxidative phosphorylation and the swelling of mitochondria
1956 • 56 citations
Zur Kenntnis der Porine des Menschen
1989 • 56 citations
The role of lipid peroxidation in the induction of cation transport in rat liver mitochondria
1983 • 55 citations
On the Regulation of the Mitochondrial Inner Membrane Anion Channel by Magnesium and Protons
1989 • 55 citations
Regulation of Ca2+ transport in brain mitochondria. II. The mechanism of the adenine nucleotides enhancement of Ca2+ uptake and retention
1990 • 55 citations
Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187
1988 • 54 citations
The regulation of mitochondrial-bound hexokinases in the liver
1985 • 54 citations
THE OSMOTIC NATURE OF MITOCHONDRIAL SWELLING PRODUCED BY CARBON TETRACHLORIDE AND INORGANIC PHOSPHATE
1958 • 54 citations
Activation of potassium ion transport in mitochondria by cadmium ion
1984 • 54 citations
Studies on mitochondria VI. The relationship between the structure, osmotic reactivity and ATPase activity of mitochondria from pigeon skeletal muscle
1955 • 54 citations
Quantitative measurements of lipide peroxide formation by normal liver mitochondria under various conditions
1960 • 54 citations
Mitochondrial respiratory control and phosphorylative activities in a magnesium-free medium
1957 • 53 citations
Alterations in liver mitochondrial function as a result of fasting and exhaustive exercise
1984 • 53 citations
Control of the mitochondrial inner membrane permeability by sulfhydryl groups
1982 • 53 citations
The cation-selective substate of the mitochondrial outer membrane pore: Single-channel conductance and influence on intermembrane and peripheral kinases
1992 • 53 citations
Cyclosporin receptor on mouse lymphocytes.
1980 • 53 citations
Modulation of Ca2+ efflux from heart mitochondria
1979 • 53 citations
Dissociation of NAD(P)+-stimulated mitochondrial Ca2+ efflux from swelling and membrane damage
1984 • 52 citations
Factors that influence phosphoenolpyruvate-induced calcium efflux from rat liver mitochondria
1974 • 52 citations
Mechanism of depletion of mitochondrial pyridine nucleotides
1960 • 52 citations
Mechanism of sodium ion independent calcium ion efflux from rat liver mitochondria
1983 • 52 citations
Quantitative and mechanistic aspects of the hydroperoxide‐induced release of Ca2+ from rat liver mitochondria
1985 • 52 citations
The Na(+)-independent Ca2+ efflux mechanism of liver mitochondria is not a passive Ca2+/2H+ exchanger.
1991 • 51 citations
Identification of a new pore in the mitochondrial outer membrane of a porin‐deficient yeast mutant
1989 • 51 citations
Structural alterations of the inner mitochondrial membrane in ischemic liver cell injury
1985 • 51 citations
Purification of a reconstitutively active K+/H+ antiporter from rat liver mitochondria.
1990 • 50 citations
Activation of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum by palmitoyl carnitine
1993 • 50 citations
Ion permeability induction by the SH cross-linking reagents in rat liver mitochondria is inhibited by the free radical scavenger, butylhydroxytoluene
1987 • 50 citations
Inhibition of Ca2+ efflux from mitochondria by nupercaine and tetracaine
1979 • 50 citations
Reye's syndrome: Mitochondrial swelling and Ca2+ release induced by Reye's plasma, allantoin, and salicylate
1986 • 50 citations
Ion permeability induced in artificial membranes by the ATP/ADP antiporter
1994 • 49 citations
Comparison of mitochondrial cationic channels in wild-type and porin-deficient mutant yeast
1990 • 49 citations
Ruthenium red-sensitive and -insensitive release of Ca2+ from uncoupled heart mitochondria
1983 • 49 citations
Correlation of optical density and oxidativ phosphorylation in reconstructed mitochondrial systems
1955 • 49 citations
Inhibition of mitochondrial-matrix inorganic pyrophosphatase by physiological [Ca2+], and its role in the hormonal regulation of mitochondrial matrix volume
1989 • 48 citations
The prevention of swelling of liver mitochondria in vitro
1956 • 48 citations
Phosphate transport processes in eukaryotic cells
1989 • 48 citations
Regulation of mitochondrial hexokinase in cultured HT 29 human cancer cells. An ultrastructural and biochemical study
1987 • 47 citations
NADH oxidation in submitochondrial particles protects respiratory chain activity against damage by adriamycin‐Fe3+
1983 • 47 citations
Quantification of lysophosphatidylethanolamine in the nanomole range.
1981 • 47 citations
Regulation of the mitochondrial outer membrane channel, VDAC
1987 • 47 citations
Long chain acyl CoAs, adenine nucleotide translocase and the coordination of the redox states of the cytosolic and mitochondrial compartments
1971 • 47 citations
Mitochondrial biochemical changes and glucose-KCl-insulin solution in cardiac infarct
1966 • 47 citations
BENEFICIAL EFFECTS OF CYCLOSPORINE ON POSTISCHEMIC LIVER INJURY IN RATS
1992 • 47 citations
Phosphorus-31 NMR visibility and characterization of rat liver mitochondrial matrix adenine nucleotides
1989 • 47 citations
Sensitivity of mitochondrial peptidyl-prolyl cis-trans isomerase, pyridine nucleotide hydrolysis and Ca2+ release to cyclosporine a and related compounds
1993 • 47 citations
The involvement of cyclosporin A binding proteins in regulating and uncoupling mitochondrial energy transduction
1992 • 46 citations
Regulation of mitochondrial metabolism by specific cellular substances. II. The nature of stimulation of mitochondrial glutamate metabolism by a cytoplasmic component
1969 • 46 citations
Dissociation between mitochondria calcium ion release and pyridine nucleotide oxidation.
1980 • 46 citations
Studies on the mechanism of oxidative phosphorylation
1958 • 46 citations
A spectrophotometric study of the spontaneous and microsome-induced swelling of rat-liver mitochondria
1960 • 46 citations
The Adenine-Nucleotide Exchange in Submitochondrial (Sonic) Particles
1977 • 46 citations
The Role of Inorganic Phosphate in the Release of Ca2+ from Rat‐Liver Mitochondria
1980 • 45 citations
Phosphorylation and redox states in ischemic liver
1973 • 45 citations
Reconstitution and partial purification of the Na(+)-selective Na+/H+ antiporter of beef heart mitochondria.
1991 • 45 citations
Effect of ADP/ATP antiporter conformational state on the suppression of the nonspecific permeability of the inner mitochondrial membrane by cyclosporine A
1990 • 45 citations
Effects of the general anaesthetic Propofol on the Ca2+‐induced permeabilization of rat liver mitochondria
1991 • 45 citations
Molecular Cellular and Behavioral Aspects of Peripheral-Type Benzodiazepine Receptors
1993 • 45 citations
Properties of the mitochondrial peptide-sensitive cationic channel studied in planar bilayers and patches of giant liposomes
1992 • 44 citations
A peptide‐sensitive channel of large conductance is localized on mitochondrial outer membrane
1991 • 44 citations
Involvement of endogenous phospholipase A2 in Ca2+ and Mg2+ movements induced by inorganic phosphate and diamide in rat liver mitochondria
1979 • 44 citations
The effect of thyroxine on the swelling of mitochondria isolated from normal and neoplastic livers
1957 • 44 citations
Multiple conductance levels in rat heart inner mitochondrial membranes studied by patch clamping
1992 • 44 citations
Production of thiol groups and retention of calcium ions by cardiac mitochondria
1980 • 44 citations
Restorative effects of spermine on oxidative phosphorylation and respiration in heat-aged mitochondria
1982 • 42 citations
Ultrastructural localisation of creatine kinase activity in the contact sites between inner and outer mitochondrial membranes of rat myocardium
1989 • 42 citations
The entrapment of the Ca2+ indicator arsenazo III in the matrix space of rat liver mitochondria by permeabilization and resealing. Na+-dependent and -independent effluxes of Ca2+ in arsenazo III-loaded mitochondria
1986 • 42 citations
Ca2+-dependent NAD(P)+-induced alterations of rat liver and hepatoma mitochondrial membrane permeability
1988 • 42 citations
Reye's Syndrome: Patient Serum Alters Mitochondrial Function and Morphology in Vitro
1977 • 41 citations
Swelling and shrinkage phenomena in liver mitochondria I. Large amplitude swelling induced by inorganic phosphate and by ATP
1965 • 41 citations
The Reactivity of ‐SH Groups in the ADP/ATP Carrier Isolated from Beef Heart Mitochondria
1982 • 41 citations
Reye's syndrome: Salicylates and mitochondrial functions
1984 • 41 citations
Ca2+-mediated activation of phosphoenolpyruvate carboxykinase occurs via release of Fe2+ from rat liver mitochondria.
1982 • 40 citations
Selective effect of inhibitors on inner mitochondrial membrane channels
1991 • 40 citations
In vivo modulation of total and mitochondrial glutathione in rat liver
1992 • 40 citations
Calcium- and phosphate-dependent release and loading of glutathione by liver mitochondria
1991 • 40 citations
Action of ‘diamide’ on some energy linked processes of rat liver mitochondria
1974 • 40 citations
The yeast cyclophilin multigene family: purification, cloning and characterization of a new isoform
1992 • 40 citations
Relationship of phosphoenolpyruvate transport, acyl coenzyme A inhibition of adenine nucleotide translocase and calcium ion efflux in guinea pig heart mitochondria
1976 • 40 citations
The Ca2+-induced permeability transition pore is involved in Ca2+-induced mitochondrial oscillations
1994 • 40 citations
Hydroperoxide-induced radical production in liver mitochondria
1986 • 40 citations
The ATP-Mg/Pi carrier of rat liver mitochondria catalyzes a divalent electroneutral exchange.
1992 • 39 citations
The mechanism of lead-induced mitochondrial Ca2+ efflux
1987 • 39 citations
Effect of Ca2+, peroxides, SH reagents, phosphate and aging on the permeability of mitochondrial membranes
1987 • 39 citations
Investigation of the dependence of the intramitochondrial [ATP]/[ADP] ratio on the respiration rate
1980 • 39 citations
Electron microscopy and image analysis of the mitochondrial outer membrane channel, VDAC
1987 • 39 citations
Na+-independent release of Ca2+ from rat heart mitochondria
1988 • 39 citations
Activation of adrenal cortex mitochondrial malic enzyme by Ca2+and Mg2+ ions
1975 • 38 citations
Phosphate transport in mitochondria: Past accomplishments, present problems, and future challenges
1993 • 38 citations
A Heat-labile Factor Required in Extrusion of Water from Mitochondria
1962 • 38 citations
Oxidative phosphorylation in infarcting baboon and dog myocardium: Effects of mitochondrial isolation and incubation media
1975 • 38 citations
On the mechanism by which Mg2+ and adenine nucleotides restore membrane potential in rat liver mitochondria deenergized by Ca2+ and phosphate
1983 • 38 citations
In-vivo and in-vitro mitochondrial membrane damages induced in mice by adriamycin and derivatives
1993 • 38 citations
Studies on Stability of Rat Liver Mitochondria
1959 • 38 citations
Opening and closing transitions for BK channels often occur in two steps via sojourns through a brief lifetime subconductance state
1993 • 38 citations
Cooperative behavior of K+ channels in the tonoplast of Chara corallina
1993 • 38 citations
Effect of the A23187 ionophore on mitochondrial membrane Mg2+ and Ca2+
1975 • 38 citations
Structural analysis of mitochondrial pores
1990 • 38 citations
Multichannel recordings from membranes which contain gap junctions. II. Substates and conductance shifts
1993 • 38 citations
Submitochondrial localization of the NAD+ glycohydrolase. Implications for the role of pyridine nucleotide hydrolysis in mitochondrial calcium fluxes.
1993 • 37 citations
The respiration of cells and mitochondria of porin deficient yeast mutants is coupled
1990 • 37 citations
The nonspecific inner membrane pore of liver mitochondria: Modulation of cyclosporin sensitivity by ADP at carboxyatractyloside-sensitive and insensitive sites
1991 • 37 citations
Dimethylurea: A radical scavenger that protects isolated pancreatic islets from the effects of alloxan and dihydroxyfumarate exposure
1980 • 37 citations
The effect of ferric iron complex on isolated rat liver mitochondria. I. Respiratory and electrochemical responses
1985 • 37 citations
The effect of phosphoenolpyruvate on the retention of calcium by liver mitochondria
1978 • 36 citations
An ADP‐sensitive cyclosporin‐A‐binding protein in rat liver mitochondria
1994 • 36 citations
Mitochondrial respiration following acute hypoxia in the perfused rat heart
1985 • 36 citations
Molecular Mechanisms of Nitrofurantoin-Induced Hepatocyte Toxicity in Aerobic versus Hypoxic Conditions
1993 • 36 citations
Some effects of Ca2+, Mg2+, and Mn2+ on the ultrastructure, light-scattering properties, and malic enzyme activity of adrenal cortex mitochondria
1976 • 36 citations
Mitochondrial swelling and electron transport I. Swelling supported by ferricyanide
1960 • 36 citations
FACTORS AFFECTING THE MAINTENANCE OF OXIDATIVE PHOSPHORYLATION IN A KIDNEY HOMOGENATE SYSTEM
1949 • 36 citations
Swelling and shrinkage phenomena in liver mitochondria III. Irreversible swelling induced by inorganic phosphate and Ca2+
1966 • 36 citations
ADP and Mg2+ requirement for Ca2+ accumulation by hog heart mitochondria. Correlation with energy coupling
1974 • 36 citations
A redox cycling mechanism of action for 2,3-dichloro-1,4-naphthoquinone with mitochondrial membranes and the role of sulfhydryl groups
1984 • 35 citations
Relationship between the Rate of Citrulline Synthesis and Bulk Changes in the Intramitochondrial ATP/ADP Ratio in Rat‐Liver Mitochondria
1981 • 35 citations
Perturbation in liver mitochondrial Ca2+ homeostasis in experimental iron overload: a possible factor in cell injury
1989 • 35 citations
A study of some factors involved in the swelling of isolated mitochondria
1956 • 35 citations
Respiration-dependent calcium ion uptake by two preparations of cardiac mitochondria. Effects of palmitoyl-coenzyme A and palmitoylcarnitine on calcium ion cycling and nicotinamide nucleotide reduction state
1980 • 35 citations
Inhibition of Electron Transport and the Swelling of Isolated Mitochondria
1959 • 35 citations
Purification and properties of a mitochondrial NAD+ glycohydrolase
1983 • 35 citations
Parallel efflux of Ca2+ and Pi in energized rat liver mitochondria
1981 • 35 citations
Effect of ATP translocation on citrulline and oxaloacetate synthesis by isolated rat liver mitochondria
1979 • 34 citations
Relation between extra- and intramitochondrial ATPADP ratios in rat liver mitochondria
1980 • 34 citations
The effect of Ca2+ and acyl coenzyme A:lysophospholipid acyltransferase inhibitors on permeability properties of the liver mitochondrial inner membrane.
1986 • 34 citations
Influence of Ca2+ on the isolation from rat brain mitochondria of a fraction enriched of boundary membrane contact sites
1988 • 34 citations
Basic peptides can be imported into yeast mitochondria by two distinct targeting pathways. Involvement of the peptide-sensitive channel of the outer membrane.
1994 • 33 citations
Reconstitution of the native mitochondrial outer membrane in planar bilayers. Comparison with the outer membrane in a patch pipette and effect of aluminum compounds
1993 • 33 citations
Inhibition of the adenine nucleotide translocator by matrix-localized palmityl-CoA in rat heart mitochondria
1984 • 33 citations
Relationship between oxidative phosphorylation efficiency and phospholipid content in rat liver mitochondria
1964 • 33 citations
Adenylate kinase is a source of ATP for tumor mitochondrial hexokinase
1985 • 33 citations
Mitochondria: DNA proteins and disease
1995 • 32 citations
On the nature of Pi‐induced, Mg2+‐prevented Ca2+ release in rat liver mitochondria
1982 • 32 citations
t-Butylhydroperoxide-induced Ca2+ efflux from liver mitochondria in the presence of physiological concentrations of Mg2+ and ATP
1986 • 32 citations
Influence of trace metals on alloxan cytotoxicity in pancreatic islets
1979 • 32 citations
Studies of cellular recovery from injury. I. Recovery from anoxia in Ehrlich ascites tumor cells.
1975 • 32 citations
The effect of Sr2+ on swelling and ATP-linked contraction of mitochondria
1965 • 31 citations
Energy Transduction and Adenine Nucleotides in Mitochondria from Rat Liver after Hypoxic Perfusion
1977 • 31 citations
H+-dependent efflux of Ca2+ from heart mitochondria
1982 • 31 citations
Glutathione and ethylenediaminetetraacetate antagonism of uncoupling of oxidative phosphorylation
1956 • 31 citations
The effect of bongkrekic acid on the Ca2+-stimulated oxidation in rat-liver mitochondria and its relation to the efflux of intramitochondrial adenine nucleotides
1971 • 31 citations
Studies on the Electron Transfer System
1966 • 31 citations
On the acylation of lysolecithin by rat-liver and brain mitochondria
1962 • 31 citations
Ca2+-induced, phospholipase-independent injury during reoxygenation of anoxic mitochondria
1993 • 31 citations
Swelling and shrinkage phenomena in liver mitochondria II. Low amplitude swelling-shrinkage cycles
1965 • 31 citations
Retention of calcium by mitochondria isolated from Ehrlich ascites tumor cells
1974 • 31 citations
Net uptake of adenine nucleotides in isolated rat liver mitochondria
1980 • 30 citations
Thermoregulatory, carboxyatractylate‐sensitive uncoupling in heart and skeletal muscle mitochondria of the ground squirrel correlates with the level of free fatty acids
1992 • 30 citations
Mitochondrial substrate carriers
1992 • 30 citations
Mechanism of nitrofurantoin toxicity and oxidative stress in mitochondria
1988 • 30 citations
Anion permeation limits the uncoupling activity of fatty acids in mitochondria
1992 • 30 citations
The nicotinamide nucleotide specificity of glutamate dehydrogenase in intact RAT-liver mitochondria
1974 • 30 citations
Binding of the intramitochondrial ADP and its relationship to adenine nucleotide translocation
1982 • 30 citations
Synergic action of calcium ions and diamide on mitochondrial swelling
1975 • 30 citations
Cloning of the cDNA coding for 14 kDa group II phospholipase A2 from rat liver
1993 • 29 citations
Cyclosporine A protects mitochondria in an in vitro model of hypoxia/reperfusion injury
1993 • 29 citations
Cyclosporin A blocks 6-hydroxydopamine-induced efflux of Ca2+ from mitochondria without inactivating the mitochondrial inner-membrane pore
1994 • 29 citations
Mg2+ restores membrane potential in rat liver mitochondria deenergized by Ca2+ and phosphate movements
1982 • 29 citations
Mitochondria: DNA proteins and disease
1994 • 29 citations
Antibodies to collagenase‐resistant terminal regions of pro‐type IV collagen recognize whole basement membrane and 7 S collagen
1981 • 29 citations
Comparison of cumene hydroperoxide- and NADPH/Fe3+/ADP-induced lipid peroxidation in heart and liver submitochondrial particles
1984 • 29 citations
Restoration of some energy linked processes lost during the ageing of rat liver mitochondria
1973 • 28 citations
the frooxidant-induced and spontaneous mitochondrial calcium release: Inhibition by meta-iodo-benzylguanidine (mibg), a substrate for mono (adpribosylation)
1990 • 28 citations
Calcium and magnesium ion losses in response to stimulants of efflux applied to heart, liver and kidney mitochondria
1981 • 28 citations
On the relationship between the uncoupler-induced efflux of K+ from heart mitochondria and the oxidation-reduction state of pyridine nucleotides.
1981 • 28 citations
ADP Requirement for prevention by a cytosolic factor of Mg2+ and Ca2+ release from rat liver mitochondria
1974 • 28 citations
A Soluble Protein Required in Mitochondrial Contraction; “Leakage” of Active Factors from Mitochondria
1960 • 28 citations
Reversible and irreversible effects of basic peptides on the mitochondrial cationic channel
1994 • 28 citations
On the Relationship between Calcium and Phosphate Transport, Transmembrane Potential and Acetoacetate-Induced Oxidation of Pyridine Nucleotides in Rat-Liver Mitochondria
1983 • 28 citations
Thyroxine-mediated release of diphosphopyridine nucleotide from mitochondrial dehydrogenases
1958 • 28 citations
Glutathione Peroxidase Protects Cultured Mammalian Cells from the Toxicity of Adriamycin and Paraquat
1993 • 27 citations
Effect of lysolecithin treatment on the structure and functions of the mitochondrial inner membrane
1973 • 27 citations
Oxaloacetate- and acetoacetate-induced calcium efflux from mitochondria occurs by reversal of the uptake pathway
1982 • 27 citations
Involvement of the ADP/ATP carrier in permeabilization processes of the inner mitochondrial membrane
1993 • 27 citations
Wirkung von Phloridzin auf Mitochondrien
1958 • 27 citations
Effect of cyclosporine A and oligomycin on non‐specific permeability of the inner mitochondrial membrane
1990 • 27 citations
ATP‐synthase complex: The mechanism of control of ion fluxes induced by cumene hydroperoxide in mitochondria
1989 • 27 citations
The Effect of Adenosine Triphosphate and Substrate on Orthophosphate-induced Mitochondrial Swelling at Acid pH
1964 • 27 citations
Regulation of transmembrane ion transport by reaction products of phospholipase A2. I. Effects of lysophospholipids on mitochondrial Ca2+ transport
1989 • 27 citations
Adenine nucleotide efflux in mitochondria induced by inorganic pyrophosphate
1982 • 27 citations
Rhein, a selective inhibitor of the DPNH-flavin step in mitochondrial electron transport
1970 • 26 citations
Effects of lysophospholipids on Ca2+ transport in rat liver mitochondria incubated at physiological Ca2+ concentrations in the presence of Mg2+, phosphate and ATP at 37° C
1984 • 26 citations
Studies on Stability of Rat Liver Mitochondria
1959 • 26 citations
Effect of pyruvate on rat heart thiol status during ischemia and hypoxia followed by reperfusion
1993 • 26 citations
The Na+‐independent Ca2+ efflux system in mitochondria is a Ca2+/2H+ exchange system
1990 • 26 citations
Effects of palmitoyl CoA and palmitoyl carnitine on the membrane potential and Mg2+ content of rat heart mitochondria
1992 • 26 citations
The action of Nupercaine on calcium efflux from rat liver mitochondria
1980 • 26 citations
Effects of 2 : 4-Dinitrophenol and Other Agents on the Swelling of Isolated Mitochondria
1959 • 26 citations
The role of hydroperoxides as calcium release agents in rat brain mitochondria
1984 • 25 citations
The effects of Mg2+ and adenine nucleotides on the sensitivity of the heart mitochondrial Na+-Ca2+ carrier to extramitochondrial Ca2+. A study using arsenazo III-loaded mitochondria
1987 • 25 citations
Studies on the distribution of potassium in the rat liver cell and the mechanism of potassium accumulation
1957 • 25 citations
Mitochondrial oxidative phosphorylation in a magnesium-free medium
1956 • 25 citations
The effect of a ferric iron complex on isolated rat-liver mitochondria. III. Mechanistic aspects of iron-induced calcium efflux
1987 • 25 citations
Binding of Active Cyclosporins to Cyclophilin A and B, Complex Formation with Calcineurin A
1993 • 25 citations
Studies on phospholipid structures in mitochondria of animals injected with cobra venom or phospholipase A
1961 • 24 citations
ATP-MgPi carrier activity in rat liver mitochondria
1992 • 24 citations
The effects of thyroxine treatment, in vivo and in vitro, on Ca2+ efflux from rat liver mitochondria
1981 • 24 citations
Studies on the effect of anterior-pituitary growth hormone on oxidative phosphorylation in rat-liver mitochondria
1961 • 24 citations
Mitochondrial swelling and phospholipid splitting induced by snake venoms
1965 • 24 citations
The role of ADP in the modulation of the calcium-efflux pathway in rat brain mitochondria
1985 • 24 citations
Inhibition of pro-oxidant-induced mitochondrial pyridine nucleotide hydrolysis and calcium release by 4-hydroxynonenal
1990 • 24 citations
Activation of potassium-dependent H+ efflux from mitochondria by cadmium and phenylarsine oxide
1981 • 24 citations
Alterations in mitochondrial Ca2+ flux by the antibiotic X-537A (lasalocid-A)
1991 • 23 citations
Reye's syndrome: Plasma-induced alterations in mitochondrial structure and function
1982 • 23 citations
Characterization of SH groups in porin of bovine heart mitochondria
1991 • 23 citations
The effect of ferric iron complex on isolated rat liver mitochondria. II. Ion movements
1985 • 23 citations
Importance of the mitochondrial outer membrane channel as a model biological channel
1987 • 23 citations
Control of cation movements in liver mitochondria by a cytoplasmic factor
1971 • 23 citations
Dual localization of the mitochondrial phospholipase A2: outer membrane contact sites and inner membrane
1992 • 22 citations
Inhibition by Sr2+ of specific mitochondrial Ca2+-efflux pathways
1983 • 22 citations
Inhibition of cation efflux by antioxidants during oscillatory ion transport in mitochondria
1979 • 22 citations
Interaction of adriamycin aglycones with isolated mitochondria
1993 • 22 citations
Calcium-ion transport by intact Ehrlich ascites-tumour cells. Role of respiratory substrates, Pi and temperature
1978 • 22 citations
Metabolic mechanisms involved in the swelling of isolated mitochondria and its prevention
1959 • 22 citations
ENZYME RELEASE FROM MITOCHONDRIA DURING REOXYGENATION OF RAT LIVER
1994 • 22 citations
Further studies on the effect of phosphoenolpyruvate on respiration-dependent calcium transport by rat heart mitochondria
1976 • 22 citations
Efflux of magnesium and potassium ions from liver mitochondria induced by inorganic phosphate and by diamide
1978 • 22 citations
Studies on the mechanism of oxidative phosphorylation
1957 • 21 citations
Mitochondrial substrate carriers
1992 • 21 citations
Effects of palmitoyl CoA and palmitoyl carnitine on the membrane potential and Mg2+ content of rat heart mitochondria
1992 • 21 citations
[34] Phospholipase A2 from rat liver mitochondria
1991 • 20 citations
Mitochondrial inner membrane permeability changes induced by octadecadienoic acid hydroperoxide. Role of mitochondrial GSH pool
1992 • 20 citations
Divicine induces calcium release from rat liver mitochondria
1985 • 20 citations
Control of the energy coupling modes in mitochondria by mercurials
1974 • 19 citations
Induction of K+ transport and swelling in isolated heart mitochondria by mercurial compounds
1967 • 19 citations
Mitochondrial Ca2+ fluxes: role of free fatty acids, acyl-CoA and acylcarnitine
1986 • 19 citations
The inhibition of mitochondrial energized processes by fluorescein mercuric acetate
1971 • 19 citations
Transient induction of the mitochondrial permeability transition by uncoupler plus a Ca2+-specific chelator
1991 • 19 citations
LONG-TERM PATIENT SURVIVAL IN A PEDIATRIC RENAL TRANSPLANTATION PROGRAM
1991 • 19 citations
The role of Ca2+ in control of malic enzyme activity in bovine adrenal cortex mitochondria
1973 • 19 citations
Effects of alloxan and streptozotocin on calcium transport in isolated mouse liver mitochondria
1982 • 19 citations
Characteristics of Ca2+ transport by corn mitochondria
1986 • 18 citations
Effect of Hydrocortisone on Mitochondrial Membrane Permeability
1958 • 18 citations
Inhibition by cyclosporine A of the prooxidant-induced but not of the sodium-induced calcium release from rat kidney mitochondria
1991 • 18 citations
A Nonphosphorylative Function of Adenosine 5'-Diphosphate in the Maintenance of Mitochondrial Integrity
1967 • 18 citations
Generation of the mitochondrial permeability transition does not involve inhibition of lysophospholipid acylation. Acyl-coenzyme A:1-acyllysophospholipid acyltransferase activity is not found in rat liver mitochondria.
1991 • 18 citations
The mechanism for Ca2+ release induced by N‐ethylmaleimide in rat liver mitochondria
1981 • 17 citations
Inhibition by cyclosporin A and butylated hydroxytoluene of the inner mitochondrial membrane permeability transition induced by Adriamycin aglycones
1990 • 17 citations
Control of mitochondrial Ca2+ retention by ADP-stimulated glutamic dehydrogenase
1987 • 17 citations
On the relationship between the mitochondrial inner membrane anion channel and the adenine nucleotide translocase.
1994 • 17 citations
Identification of the Reye's Syndrome “serum factor”
1980 • 17 citations
Effect of succinate on mitochondrial lipid peroxidation. 1. Comparative studies on ferrous ion and ADP · Fe/NADPH-induced peroxidation
1987 • 16 citations
An in vitro model for cyclosporin A-induced interference of intrathymic clonal elimination.
1990 • 16 citations
The effect of analogues of thyroxine and 2,4-dinitrophenol on the swelling of mitochondria
1959 • 16 citations
Prevention of Ca2+ induced cation efflux from liver mitochondria by a cytoplasmic factor and by oligomycin
1971 • 16 citations
Reye's syndrome: The effect of patient serum on mitochondrial respiration in vitro
1977 • 16 citations
Prooxidant‐Induced Ca2+ Release from Liver Mitochondria
1992 • 16 citations
The function of ATP/ADP translocator in the regulation of mitochondrial respiration during development of heart ischemic injury
1993 • 15 citations
Oxidative phosphorylation and respiratory control in lysolecithin treated electron transport particles
1974 • 15 citations
Net Adenine Nucleotide Transport in Rat Kidney Mitochondria
1993 • 14 citations
Bidirectional transport of spermine in rat liver mitochondria
1992 • 14 citations
Effects of substrates on the swelling and loss of pyridine/nucleotides from rat-liver mitochondria
1959 • 14 citations
Effects of the membrane potential upon the Ca2+‐ and cumene hydroperoxide‐induced permeabilization of the inner mitochondrial membrane
1991 • 14 citations
Reconstruction of Coupled Phosphorylation in the Succinic Oxidase System
1955 • 14 citations
Uncoupler-stimulated release of Ca2+ from Ehrlich ascites tumor cell mitochondria
1985 • 14 citations
Ca2+ transport and oxidative damage of mitochondria.
1993 • 14 citations
Interacting effects of dibutylchloromethyltin chloride, 2,3-dimercaptopropanol, and other reagents on mitochondrial respiration and K+ flux
1983 • 14 citations
The interaction of tributyltin with the mitochondrial calcium transport system of rat liver
1978 • 14 citations
Inhibition of ruthenium red-insensitive mitochondrial Ca2+ release and its pyridine nucleotide specificity
1982 • 14 citations
Rapid efflux of Ca2+ from heart mitochondria in the presence of inorganic pyrophosphate
1984 • 14 citations
Respiration‐dependent stimulation by inorganic phosphate of Mg2+ release from rat liver mitochondria
1976 • 13 citations
Beneficial effect of cyclosporine pretreatment in preventing ischemic damage to the liver in dogs.
1988 • 13 citations
Solubilization and reconstitution of the mitochondrial peptide-sensitive channel
1993 • 13 citations
THE BENEFICIAL EFFECT OF PRETRANSPLANT CYCLOSPORINE THERAPY ON RECIPIENT RATS GRAFTED WITH A 12-HOUR COLD-STORED LIVER
1990 • 13 citations
Effect of malonyl‐CoA on calcium uptake and pyridine nucleotide redox state in rat liver mitochondria
1979 • 13 citations
Isolation of Mitochondrial Cyclophilin from Bovine Heart
1993 • 13 citations
Interaction of Sr2+ with Ca2+-induced Ca2+ release in mitochondria
1988 • 13 citations
A specific ADP requirement in the course of Ca++ and phosphate accumulation in mitochondria
1970 • 12 citations
Inhibition of ruthenium red-induced Ca2+ efflux from liver mitochondria by the antibiotic X-537A
1984 • 12 citations
Do Mercurials and Thyroxine Potentiate Calcium-Dependent Phospholipase Activity in Mitochondria?
1977 • 12 citations
The contribution of adenine nucleotide loss to ischemia-induced impairment of rat kidney cortex mitochondria
1992 • 11 citations
Butylated hydroxytoluene prevents cumene hydroperoxide-induced Ca2+ release from liver mitochondria by inhibiting pyridine nucleotide hydrolysis
1992 • 11 citations
The Phospholipase A2Induced Increase in the Permeability of Phospholipid Membranes to Ca2⊕and H⊕Ions
1989 • 11 citations
Effects of high and low pH on Ca2+i and on cell injury evoked by anoxia in perfused rat hepatocytes
1994 • 11 citations
Abolition by 2 : 4-Dinitrophenol of the Protective Effect of Succinate and Adenine Nucleotides on the Onset of the Thyroxine-induced Swelling of Liver Mitochondria
1960 • 11 citations
Ion transport in rat liver mitochondria: the effect of the incubation medium osmolarity
1985 • 11 citations
The losses of adenine nucleotide accompanying efflux of Ca2+ from heart, liver and kidney mitochondria
1982 • 11 citations
Coupling of energy to mitochondrial swelling
1963 • 11 citations
Ca2+-mediated action of long-chain acyl-CoA on liver mitochondria energy-linked processes
1989 • 10 citations
Molecular biology of mitochondrial transport systems
1995 • 10 citations
Effect of cyclosporin A and trifluoperazine on rat liver mitochondria swelling and lipid peroxidation.
1993 • 9 citations
Studies on the Mechanisms Controlling Time of Onset and Extent of Mitochondrial Swelling*
1966 • 9 citations
Swelling of Fresh and Aged Liver Mitochondria as affected by Succinate, Adenine Nucleotides and Thyroxine
1960 • 9 citations
Opposing actions of Ca++ and ATP plus Mg++ in controlling the kynurenine aminotransferase activity of isolated rat kidney mitochondria
1977 • 9 citations
Intracellular free Ca2+, Na+, and H+ concentrations in the isolated perfused rat heart during the Ca2+ paradox
1994 • 9 citations
Alleviation of 3.5-hour warm ischemic injury of the liver in pigs by cyclosporine pretherapy.
1991 • 8 citations
Role of C-factor in water uptake and extrusion by mitochondria and interference by various drugs
1962 • 8 citations
Effects of Oxygen and Antioxidants on the Mitochondrial Ca-Retention Capacity
1993 • 8 citations
Some observations on the swelling of mitochondria caused by naturally-occurring agents
1961 • 8 citations
Calcium ion activation of the anion‐conducting channel in the rat liver mitochondrial inner membrane
1990 • 7 citations
A reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria
1987 • 7 citations
Regulation of lipid peroxidation by ATP synthetase substrates in rat liver mitochondria
1986 • 6 citations
The mechanism of calcium-dependent activation of respiration of liver mitochondria from hibernating ground squirrels, Citellus undulatus
1993 • 6 citations
Cyclosporin and mitochondrial dysfunction
1990 • 6 citations
The role of phospholipase A2 in lipid peroxidation‐induced fall of membrane potential of rat liver mitochondria
1990 • 6 citations
The pH‐dependent anion‐conducting channel of the mitochondrial inner membrane is potently inhibited by zinc ions
1993 • 6 citations
On the State of Calcium Ions in Isolated Rat Liver Mitochondria. II. Effects of Phosphate and pH on Ca2⊕-Induced Ca2⊕Release
1984 • 6 citations
The relationship between the temperature and the effect of 2,4 dinitrophenol on the swelling of isolated mitochondria
1959 • 6 citations
Reduction of phosphate-induced dysfunction in rat heart mitochondria by carnitine
1990 • 5 citations
Stimulation of phospholipase A2 activity in mitochondria by magnesium and polyamines.
1994 • 5 citations
Bidirectional Transport of Spermine Across the Inner Membrane of Liver Mitochondria
1988 • 5 citations
Functional and structural changes induced by phospholipase C in intact mitochondria and submitochondrial particles
1976 • 5 citations
Cyclosporin and mitochondrial phospholipid degradation
1990 • 5 citations
Monoclonal antibodies against rat liver mitochondrial phospholipase a2: Epitope analysis and application in western blotting
1993 • 4 citations
On the mechanism of oligomycin inhibition of Ca2+‐induced mitochondrial respiration
1991 • 4 citations
PROTECTION OF PIG LIVER AGAINST NORMOTHERMIC ISCHEMIA BY IMMUNOSUPPRESSANTS CYCLOSPORINE AND AZATHIOPRINE
1992 • 3 citations
Protection of pig liver against normothermic ischemia by immunosuppressants cyclosporine and azathioprine.
1992 • 3 citations
Iron-induced Ca2+ release from rat liver mitochondria via H2O2 metabolism
1987 • 3 citations
Lipoperoxidation associated with mitochondrial membrane permeabilization in the presence of Ca2+.
1991 • 2 citations
Alteration to the permeability of plant and animal mitochondria submitted to Ca2+ releasing agents
1992 • 2 citations
The Role of Ca 2+ in the Process of Mitochondrial Damage Associated with Oxidative Stress
1993 • 1 citations
A study of the inner membrane anion channel of rat liver mitochondria.
1990 • 1 citations
Deleted Work
1955 • 0 citations