Mitochondrial Generation of Oxygen Radicals During Reoxygenation of Ischemic Tissues

The American Journal of Physiology

1899 • 5,863 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

1988 • 1,709 citations

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1980 • 1,609 citations

The cellular production of hydrogen peroxide

1972 • 1,526 citations

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

1985 • 1,201 citations

Induction of Manganous Superoxide Dismutase by Tumor Necrosis Factor: Possible Protective Mechanism

1988 • 933 citations

Role of ubiquinone in the mitochondrial generation of hydrogen peroxide

1976 • 656 citations

Progress in Clinical and Biological Research

1989 • 568 citations

The effect of hyperoxia on superoxide production by lung submitochondrial particles

1982 • 442 citations

Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration

1975 • 403 citations

Hyperoxia increases H2O2 release by lung mitochondria and microsomes

1982 • 336 citations

Enhancement of hydrogen peroxide formation by protophores and ionophores in antimycin-supplemented mitochondria

1980 • 273 citations

Studies on Cytochrome c Peroxidase

1965 • 260 citations

Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondrial damage.

1986 • 258 citations

Induction of mitochondrial manganese superoxide dismutase by interleukin 1

1988 • 232 citations

Free radical-producing enzyme, xanthine oxidase, is undetectable in human hearts

1987 • 199 citations

Mitochondrial H₂O₂ formation: Relationship with energy conservation

1973 • 179 citations

Increase in manganese superoxide dismutase activity in the mouse heart after X-irradiation

1987 • 168 citations

Induction of superoxide dismutase by oxygen in neonatal rat lung.

1977 • 138 citations

Radioprotection of mice by superoxide dismtuase

1975 • 118 citations

Maintenance of Energy-Linked Functions in Rat-Liver Mitochondria Aged in the Presence of Nupercaine

1972 • 94 citations

Effects of ischemia on the isolation and function of canine cardiac sarcoplasmic reticulum

1986 • 67 citations

Mitochondrial Regulation of Intracellular Calcium

1982 • 53 citations

Enhancement of ATPase Activity by a Lipid Peroxide of Arachidonic Acid in Rat Brain Microvessels

1986 • 47 citations

Susceptibility of mitochondrial membranes to calcium and reactive oxygen species: implications for ischemic and toxic tissue damage.

1988 • 44 citations

Mitochondrial inner membrane enzyme defects in porcine myocardial ischemia

1981 • 23 citations

Rapid procedure for the isolation of cytochrome c peroxidase

1986 • 21 citations