Destruction of Phosphilipids and Respiratory‐Chain Activity in Pig=Heart Submitochondrial Particles Induced by an Adriamycin‐Iron Complex

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Phosphorus Assay in Column Chromatography

1959 • 12,895 citations

Free Radicals in Biology

1976 • 1,879 citations

Adriamycin: The Role of Lipid Peroxidation in Cardiac Toxicity and Tumor Response

1977 • 1,116 citations

Adriamycin

1974 • 1,051 citations

Appendix—Spectrum of horse-heart cytochrome c

1959 • 802 citations

Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides

1982 • 779 citations

Spectrophotometric determination of serum iron at the submicrogram level with a new reagent (ferrozine)

1971 • 767 citations

Toxic drug effects associated with oxygen metabolism: Redox cycling and lipid peroxidation

1981 • 650 citations

Tissue fractionation studies. 5. The association of acid phosphatase with a special class of cytoplasmic granules in rat liver

1955 • 625 citations

Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin

1977 • 545 citations

Free Radical Mechanisms of Lipid Damage and Consequences for Cellular Membranes

1976 • 465 citations

[13] Preparation, properties, and conditions for assay of mitochondria: Slaughterhouse material, small-scale

1967 • 455 citations

The detection of oxidation in liposome preparations

1970 • 408 citations

Cardiotoxicity of adriamycin and related anthracyclines

1976 • 377 citations

Evidence of a specific complex between adriamycin and negatively-charged phospholipids

1980 • 307 citations

The mechanism of the oxidation of unsaturated fatty acids catalyzed by hematin compounds

1953 • 263 citations

Adriamycin stimulated superoxide formation in submitochondrial particles

1977 • 256 citations

Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine.

1981 • 247 citations

Adriamycin (NSC-123,127): a new antibiotic with antitumor activity.

1969 • 239 citations

Oxidative destruction of erythrocyte ghost membranes catalyzed by the doxorubicin-iron complex

1982 • 238 citations

The Role of Iron in Enzymatic Lipid Peroxidation

1982 • 233 citations

Cardiolipin requirement by cytochrome oxidase and the catalytic role of phospholipid

1980 • 226 citations

Dimethoxypropane Induced Transesterification of Fats and Oils in Preparation of Methyl Esters for Gas Chromatographic Analysis.

1964 • 214 citations

Mechanism of adriamycin cardiotoxicity: Evidence for oxidative stress

1981 • 210 citations

NADH- and NADPH-dependent lipid peroxidation in bovine heart submitochondrial particles. Dependence on the rate of electron flow in the respiratory chain and an antioxidant role of ubiquinol

1980 • 200 citations

Free-Radical Intermediates in the Metabolism of Toxic Chemicals

1982 • 197 citations

[3] Preparation and properties of NADH: Ubiquinone oxidoreductase (complex I), EC 1.6.5.3

1978 • 190 citations

Stimulation by adriamycin of rat heart and liver microsomal NADPH-dependent lipid peroxidation

1981 • 166 citations

Evidence of a complex between adriamycin derivatives and cardiolipin: Possible role in cardiotoxicity

1980 • 156 citations

Inhibition of coenzyme Q10-enzymes, succinoxidase and NADH-oxidase, by adriamycin and other quinones having antitumor activity

1974 • 153 citations

[87] Energy-coupling in nonphosphorylating submitochondrial particles

1967 • 152 citations

Adriamycin inactivates cytochrome c oxidase by exclusion of the enzyme from its cardiolipin essential environment

1982 • 143 citations

Affinity of adriamycin to phospholipids a possible explanation for cardiac mitochondrial lesions

1976 • 128 citations

Mitochondrial iron not bound in heme and iron-sulfur centers. Estimation, compartmentation and redox state

1980 • 104 citations

Specificity and binding affinity of phospholipids to the high-affinity cardiolipin sites of beef heart cytochrome c oxidase

1982 • 103 citations

Lipid oxidation in biological membranes

1975 • 98 citations

Alteration of inner-membrane components and damage to electron-transfer activities of bovine heart submitochondrial particles induced by NADPH-dependent lipid peroxidation

1982 • 85 citations

Reduced Triphosphopyridine Nucleotide Oxidase-catalyzed Alterations of Membrane Phospholipids

1972 • 75 citations

Solution chemistry studies of adriamycin-iron complexes present in vivo

1980 • 68 citations

Decompostion of unsaturated phospholipid by iron-ADP-adriamycin co-ordination complex

1981 • 58 citations

Bioenergetics in clinical medicine: prevention by forms of coenzyme Q of the inhibition by adriamycin of coenzyme Q10-enzymes in mitochondria of the myocardium.

1976 • 56 citations

A protective effect of coenzyme Q10 on the adriamycin-induced cardiotoxicity in the isolated perfused rat heart

1981 • 53 citations

Rescue by coenzyme Q10 from electrocardiographic abnormalities caused by the toxicity of adriamycin in the rat.

1978 • 43 citations

Measurement of Polyunsaturated Fatty Acids

1957 • 41 citations

Reduced Nicotinamide Adenine Dinucleotide Phosphate-dependent Lipid Peroxidation by Beef Heart Submitochondrial Particles1

1975 • 38 citations

Separation of cellular phospholipid, neutral lipid and cholesterol by high-pressure liquid chromatography

1981 • 32 citations

Further studies on adriamycin induced in vitro lipid peroxidation

1982 • 14 citations