Evidence for the existence of an inner membrane anion channel in mitochondria

Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism

1961 • 4,416 citations

CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION

1966 • 3,631 citations

A23187: A Divalent Cation Ionophore

1972 • 1,182 citations

Regulation of Metabolic Processes in Mitochondria

1967 • 1,182 citations

Energy of an Ion crossing a Low Dielectric Membrane: Solutions to Four Relevant Electrostatic Problems

1969 • 832 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 826 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 751 citations

Biochemistry of Mitochondria

1966 • 694 citations

Myocardial calcium and magnesium in acute ischemic injury.

1972 • 628 citations

Metabolite Transport in Mitochondria

1979 • 618 citations

Relationship between configuration, function, and permeability in calcium-treated mitochondria.

1976 • 610 citations

Water Uptake and Extrusion by Mitochondria in Relation to Oxidative Phosphorylation

1962 • 550 citations

Kinetics of calcium accumulation in acute myocardial ischemic injury.

1972 • 507 citations

Reperfusion of the ischemic myocardium

1977 • 469 citations

Effect of surface active agents on the latent ATPASE of mitochondira

1956 • 455 citations

SYSTEMS USED FOR THE TRANSPORT OF SUBSTRATES INTO MITOCHONDRIA

1968 • 449 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 442 citations

Transport of protons across membranes by weak acids.

1980 • 391 citations

Translocation of some Anions Cations and Acids in Rat Liver Mitochondria

1969 • 371 citations

Brown adipose tissue mitochondria

1979 • 369 citations

Dynamics of energy‐transducing membranes

1975 • 348 citations

GRAMICIDIN AND ION TRANSPORT IN ISOLATED LIVER MITOCHONDRIA

1965 • 324 citations

Mitochondrial calcium transport

1980 • 304 citations

The osmotic behavior and permeability to non-electrolytes of mitochondria

1955 • 293 citations

Biochemical and Osmotic Properties of Skeletal Muscle Mitochondria

1954 • 289 citations

The relationship between mitochondrial membrane permeability, membrane potential, and the retention of Ca2+ by mitochondria.

1980 • 288 citations

FRACTIONATION OF MAMMALIAN LIVER CELLS BY DIFFERENTIAL CENTRIFUGATION

1946 • 277 citations

Total ischemia in dog hearts, in vitro. 1. Comparison of high energy phosphate production, utilization, and depletion, and of adenine nucleotide catabolism in total ischemia in vitro vs. severe ischemia in vivo.

1981 • 275 citations

Acyl-CoA inhibition of adenine nucleotide translocation in ischemic myocardium

1975 • 267 citations

Changes in tissue levels of carnitine and other metabolites during myocardial ischemia and anoxia

1978 • 249 citations

Chloride‐Hydroxide Exchange across Mitochondrial, Erythrocyte and Artificial Lipid Membranes Mediated by Trialkyl‐ and Triphenyltin Compounds

1970 • 249 citations

Swelling and contraction of the mitochondrial matrix. I. A structural interpretation of the relationship between light scattering and matrix volume.

1985 • 237 citations

Metabolite transport in mitochondria: an example for intracellular membrane function.

1970 • 229 citations

Early phase of myocardial ischemic injury and infarction

1969 • 227 citations

ISCHEMIC INJURY OF MYOCARDIUM*

1969 • 216 citations

Extracellular potassium accumulation in acute myocardial ischemia*

1984 • 211 citations

Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexlycarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC

1986 • 210 citations

Reversal of ischemic mitochondrial dysfunction.

1981 • 191 citations

Brown‐adipose‐tissue mitochondria: the regulation of the 32 000‐M_r uncoupling protein by fatty acids and purine nucleotides

1983 • 183 citations

CALCIUM ION ACCUMULATION AND VOLUME CHANGES OF ISOLATED LIVER MITOCHONDRIA. CALCIUM ION-INDUCED SWELLING

1965 • 164 citations

Ionophore A23187: the effect of proton concentration on complex formation with divalent and monovalent cations and the demonstration of potassium(1+) ion transport in mitochondria mediated by A23187

1976 • 163 citations

Effect of long-chain fatty acids and acyl-CoA on mitochondrial permeability, transport, and energy-coupling processes

1976 • 162 citations

On the mechanism of regulation of the mitochondrial K+/H+ exchanger.

1980 • 160 citations

Allosteric inhibition of the Ca2+-activated hydrophilic channel of the mitochondrial inner membrane by nucleotides

1980 • 157 citations

Effects of Trialkyltin and Triphenyltin Copounds on Mitochondrial Respiration

1970 • 151 citations

Structure and Function of Membrane Proteins

1983 • 145 citations

Ion Transport by Heart Mitochondria

1970 • 142 citations

Fatty Acids as Acute Regulators of the Proton Conductance of Hamster Brown‐Fat Mitochondria

1982 • 140 citations

Pore size and properties of channels from mitochondria isolated fromNeurospora crassa

1980 • 136 citations

Determination of the Proton Electrochemical Gradient across Biological Membranes

1984 • 134 citations

The Effective Proton Conductance of the Inner Membrane of Mitochondria from Brown Adipose Tissue

1977 • 133 citations

Brown-Adipose-Tissue Mitochondria. The Influence of Albumin and Nucleotides on Passive Ion Permeabilities

1973 • 130 citations

Reversal of ischemic mitochondrial dysfunction.

1979 • 117 citations

Swelling and contraction of the mitochondrial matrix. II. Quantitative application of the light scattering technique to solute transport across the inner membrane.

1985 • 114 citations

The effect of N,N′-dicyclohexylcarbodiimide on enzymes of bioenergetic relevance

1984 • 113 citations

Compartmentation of Heart Mitochondria

1965 • 110 citations

The inhibition of translocation of adenine nucleotides through mitochondrial membranes by oleate

1967 • 110 citations

Studies on the mechanism of uncoupling by amine local anesthetics. Evidence for mitochondrial proton transport mediated by lipophilic ion pairs.

1983 • 105 citations

Quinine inhibition of Na+ and K+ transport provides evidence for two cation/H+ exchangers in rat liver mitochondria.

1982 • 103 citations

Proton electrochemical gradient and rate of controlled respiration in mitochondria

1978 • 102 citations

Swelling and shrinkage phenomena in liver mitochondria VI. Metabolism-independent swelling coupled to ion movement

1967 • 99 citations

Stimulation of mitochondrial calcium ion efflux by thiol-specific reagents and by thyroxine. The relationship to adenosine diphosphate retention and to mitochondrial permeability

1979 • 96 citations

Characterization of phosphate efflux pathways in rat liver mitochondria

1983 • 93 citations

Differential effects of mercurial reagents on membrane thiols and on the permeability of the heart mitochondrion

1970 • 91 citations

Palmitoyl coenzyme A: A possible physiological regulator of nucleotide binding to brown adipose tissue mitochondria

1977 • 91 citations

The 35 kDa DCCD-binding protein from pig heart mitochondria is the mitochondrial porin

1985 • 87 citations

Active transport and binding in mitochondria

1973 • 85 citations

On the mechanism of A23187-induced potassium efflux in rat liver mitochondria.

1980 • 84 citations

The Acute Regulation of Mitochondrial Proton Conductance in Cells and Mitochondria from the Brown Fat of Cold‐Adapted and Warm‐Adapted Guinea Pigs

1982 • 84 citations

Ion transport by heart mitochondria

1968 • 84 citations

Ion transport by heart mitochondria. XVII. Energy-linked alteration of the permeability of heart mitochondria to chloride and other anions

1970 • 80 citations

Electroneutral H+-K+ exchange in liver mitochondria Regulation by membrane potential

1983 • 76 citations

Correlated Effluxes of Adenine Nucleotides, Mg²⁺ and Ca²⁺ Induced in Rat‐Liver Mitochondria by External Ca²⁺ and Phosphate

1981 • 75 citations

On the mechanism by which dicyclohexylcarbodiimide and quinine inhibit K+ transport in rat liver mitochondria.

1986 • 75 citations

Mg2+ and the permeability of heart mitochondria to monovalent cations

1976 • 74 citations

Hamster Brown‐Adipose‐Tissue Mitochondria

1974 • 74 citations

The Osmotic Behavior of the Sucrose-inaccessible Space of Mitochondrial Pellets from Rat Liver

1959 • 74 citations

Identification of an 82,000-dalton protein responsible for K+/H+ antiport in rat liver mitochondria.

1984 • 73 citations

Effect of Ligation of Portal Vein on Liver Mitochondrial Metabolism

1971 • 72 citations

K+/H+ antiport in heart mitochondria.

1984 • 71 citations

Purification of VDAC (Voltage-dependent anion-selective channel) from rat liver mitochondria

1983 • 70 citations

CALCIUM ION ACCUMULATION AND VOLUME CHANGES OF ISOLATED LIVER MITOCHONDRIA. REVERSAL OF CALCIUM ION-INDUCED SWELLING

1965 • 69 citations

Myocardial ischemia: Correlation of mitochondrial adenine nucleotide and respiratory function

1984 • 66 citations

Thermodynamic and Kinetic Aspects of the Interconversion of Chemical and Osmotic Energies in Mitochondria

1971 • 66 citations

Effect of butyl malonate and mersalyl on anion-exchange reactions in rat-liver mitochondria

1969 • 65 citations

Effect of Mg2+ depletion of mitochondria on their permeability to K+: The mechanism by which ionophore A23187 increases K+ permeability

1977 • 65 citations

Adenine nucleotide translocase as a site of regulation by ADP of the rat liver mitochondria permeability to H+ and K+ lons

1980 • 65 citations

Relationships between Ca2+ release, Ca2+ cycling, and Ca2+-mediated permeability changes in mitochondria.

1985 • 65 citations

Osmotic swelling of heart mitochondria in acetate and chloride salts

1978 • 62 citations

Energy-dependent contraction of swollen heart mitochondria.

1977 • 62 citations

Effect of fatty acids and acyl‐CoA on the permeability of mitochondrial membranes to monovalent cations

1974 • 60 citations

Decrease in Mitochondrial Levels of Adenine Nucleotides and Concomitant Mitochondrial Dysfunction in Ischemic Rat Liver1

1983 • 59 citations

Swelling and Shrinkage Phenomena in Liver Mitochondria

1966 • 55 citations

On the relative roles of Ca2+ and Mg2+ in regulating the endogenous K+/H+ exchanger of rat liver mitochondria.

1982 • 53 citations

Osmotic Properties of Mitochondria

1967 • 53 citations

Alterations in liver mitochondrial function as a result of fasting and exhaustive exercise

1984 • 53 citations

Dissociation of NAD(P)+-stimulated mitochondrial Ca2+ efflux from swelling and membrane damage

1984 • 52 citations

The Mechanism of Ion Translocation in Mitochondria. 2. Active Transport and Proton Pump

1970 • 51 citations

Induction of electroneutral exchanges of H⁺ with K⁺ in rat liver mitochondria

1978 • 50 citations

Ion transport in live mitochondria

1967 • 50 citations

Of oxygen, fuels, and living matter

1981 • 50 citations

Matrix magnesium and the permeability of heart mitochondria to potassium ion.

1986 • 49 citations

Mitochondrial function and intracellular calcium in anoxic cardiac myocytes

1986 • 45 citations

The Mechanism of Ion Translocation in Mitochondria. 1. Coupling of K+ and H+ Fluxes

1970 • 44 citations

Involvement of endogenous phospholipase A2 in Ca2+ and Mg2+ movements induced by inorganic phosphate and diamide in rat liver mitochondria

1979 • 44 citations

Ion transport by heart mitochondria. XVIII. Swelling and contraction of heart mitochondria suspended in ammonium chloride

1970 • 43 citations

Biochemical effects of the hypoglycaemic compound diphenyleneiodonium. Catalysis of anion–hydroxyl ion exchange across the inner membrane of rat liver mitochondria and effects on oxygen uptake

1972 • 42 citations

Swelling and shrinkage phenomena in liver mitochondria I. Large amplitude swelling induced by inorganic phosphate and by ATP

1965 • 41 citations

Photoacoustic photocalorimetry and spectroscopy of Halobacterium halobium purple membranes

1982 • 41 citations

Osmotically active space in mitochondria

1966 • 39 citations

An Anion-Conducting Pore in the Mitochondrial Inner Membrane

1979 • 39 citations

Induction of respiration-dependent net efflux of K+ from heart mitochondria by depletion of endogenous divalent cations.

1980 • 38 citations

Mechanism of active shrinkage in mitochondria II. Coupling between strong electrolyte fluxes

1976 • 37 citations

Ion-Translocation in Energy-Conserving Membrane Systems

1972 • 36 citations

On the mechanism of mercurial‐induced permeability of the mitochondrial membrane to K⁺

1979 • 36 citations

A study of structure of the mitochondrial membrane system

1966 • 36 citations

Ionic environment and the contraction of isolated rat-liver mitochondria by adenosine triphosphate

1961 • 33 citations

Swelling and shrinkage phenomena in liver mitochondria II. Low amplitude swelling-shrinkage cycles

1965 • 31 citations

Mitochondrial Acyl-CoA, adenine nucleotide translocase activity and oxidative phosphorylation in myocardial ischaemia

1981 • 29 citations

Energy-linked alteration of mitochondrial permeability to anions

1969 • 29 citations

Restoration of some energy linked processes lost during the ageing of rat liver mitochondria

1973 • 28 citations

On the mechanism of energy-dependent contraction of swollen mitochondria

1976 • 27 citations

Effect of some organometallic compounds on the permeability of chloroplast membranes

1970 • 25 citations

Metabolism-dependent mitochondrial shrinkage coupled to ion movement

1966 • 25 citations

Inhibition of electrogenic anion entry into rat liver mitochondria by N,N'‐dicyclohexylcarbodiimide

1982 • 24 citations

Energy-Dependent contraction of swollen heart mitochondria—Activation by butacaine

1979 • 24 citations

Inhibition of cation efflux by antioxidants during oscillatory ion transport in mitochondria

1979 • 22 citations

Ion transport by heart mitochondria

1972 • 21 citations

Induction of electroneutral exchanges of H⁺ with Na⁺, divalent and organic cations in rat liver mitochondria

1978 • 20 citations

Is the mitochondrial dicyclohexylcarbodiimide‐reactive protein of M_r 33 000 identical with the phosphate transport protein?

1981 • 19 citations

Permeability of the mitochondrial membrane to bicarbonate ions

1977 • 18 citations

The effects of diphenyleneiodonium and of 2,4-dichlorodiphenyleneiodonium on mitochondrial reactions. Mechanism of the inhibition of oxygen uptake as a consequence of the catalysis of the chloride/hydroxyl-ion exchange

1976 • 17 citations

The influence of permeant anions upon mitochondrial energy conservation by means of a K+ gradient

1972 • 17 citations

Mitochondrial permeability to chloride ion

1975 • 17 citations

Inhibition of mitochondrial anion permeability by local anaesthetics

1978 • 17 citations

Correlation of mitochondrial function and ischemic contracture

1980 • 16 citations

Phosphate transport across the mitochondrial membrane: The influence of thiol oxidation and of Mg⁺⁺ on inhibition by mercurials

1975 • 16 citations

Energy-dependent contraction of swollen mitochondria: Activation by nigericin

1977 • 14 citations

Phosphate retention and release during ATP hydrolysis in liver mitochondria

1979 • 9 citations

Permeability effects of organomercurials

1972 • 9 citations

The pathway of inorganic-phosphate efflux from isolated liver mitochondria during adenosine triphosphate hydrolysis

1980 • 7 citations

Effects of Anions on Swelling, Respiration, and Phosphorylation of Isolated Corn Mitochondria

1975 • 4 citations

Ethylmercurithiosalicylate — a new reagent for the study of phosphate transport in mitochondria

1980 • 2 citations

Inhibition of malate transport and activation of phosphate transport in mitochondria by ethylmercurithiosalicylate

1980 • 1 citations