Mechanism of alloxan-induced calcium release from rat liver mitochondria.

[7] Mitochondrial respiratory control and the polarographic measurement of ADP : O ratios

1967 • 1,785 citations

Toxic drug effects associated with oxygen metabolism: Redox cycling and lipid peroxidation

1981 • 650 citations

DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation

1982 • 530 citations

[56] DT diaphorase

1967 • 521 citations

The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria

1978 • 380 citations

Regulation of Ca ²⁺ release from mitochondria by the oxidation-reduction state of pyridine nucleotides

1978 • 364 citations

One-electron-transfer reactions in biochemical systems V. Difference in the mechanism of quinone reduction by the NADH dehydrogenase and the NAD(P)H dehydrogenase (DT-diaphorase)

1970 • 335 citations

Mitochondrial calcium transport

1980 • 304 citations

Alloxan-induced diabetes—evidence for hydroxyl radical as a cytotoxic intermediate

1976 • 249 citations

Oxidation of glutathione during hydroperoxide metabolism

1984 • 243 citations

Mitochondria and Microsomes

1982 • 223 citations

Hydroperoxide-induced loss of pyridine nucleotides and release of calcium from rat liver mitochondria.

1980 • 220 citations

Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro

1979 • 206 citations

Hydroperoxides can modulate the redox state of pyridine nucleotides and the calcium balance in rat liver mitochondria

1979 • 205 citations

Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates

1978 • 188 citations

Regulated release of Ca2+ from respiring mitochondria by Ca2+/2H+ antiport.

1979 • 182 citations

Superoxide dismutase is a prophylactic against alloxan diabetes

1981 • 166 citations

Inhibition of Alloxan Action in Isolated Pancreatic Islets by Superoxide Dismutase, Catalase, and a Metal Chelator

1980 • 159 citations

The metabolism of menadione impairs the ability of rat liver mitochondria to take up and retain calcium.

1982 • 159 citations

Pyridine‐nucleotide oxidation, Ca²⁺ cycling and membrane damage during tert‐butyl hydroperoxide metabolism by rat‐liver mitochondria

1984 • 135 citations

Quinone-stimulated superoxide formation by subcellular fractions, isolated hepatocytes, and other cells.

1981 • 119 citations

Disequilibrium between steady-state Ca²⁺ ion accumulation ratio and membrane potential in mitochondria. Pathway and role of Ca²⁺ ion efflux

1977 • 118 citations

The Energy‐State of Mitochondria during the Transport of Ca²⁺

1980 • 110 citations

Stimulation of mitochondrial calcium ion efflux by thiol-specific reagents and by thyroxine. The relationship to adenosine diphosphate retention and to mitochondrial permeability

1979 • 96 citations

Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase.

1980 • 88 citations

ADP-ribosylation in inner membrane of rat liver mitochondria.

1983 • 86 citations

The prevention of alloxan-induced diabetes in mice by dimethyl sulfoxide

1977 • 86 citations

Evidence for penetrant and non‐penetrant thiol reagents and their use in the location of rat liver mitochondrial D(‐)‐β‐hydroxybutyrate dehydrogenase

1975 • 83 citations

ATP Prevents both Hydroperoxide‐Induced Hydrolysis of Pyridine Nucleotides and Release of Calcium in Rat Liver Mitochondria

1981 • 75 citations

REACTIONS OF ALLOXAN AND DIALURIC ACID WITH THE SULFHYDRYL GROUP

1949 • 68 citations

The effect of superoxide generation on the ability of mitochondria to take up and retain Ca²⁺

1982 • 66 citations

The hydroperoxide‐induced release of mitochondrial calcium occurs via a distinct pathway and leaves mitochondria intact

1982 • 65 citations

Possible participation of membrane thiol groups on the mechanism of NAD(P)+-stimulated Ca2+ efflux from mitochondria

1984 • 60 citations

Efflux of Ca²⁺andMn²⁺ from rat liver mitochondria

1978 • 53 citations

Dissociation of NAD(P)+-stimulated mitochondrial Ca2+ efflux from swelling and membrane damage

1984 • 52 citations

Separate pathways for Ca²⁺ uptake and release in liver mitochondria

1978 • 43 citations

Dimethylurea: A radical scavenger that protects isolated pancreatic islets from the effects of alloxan and dihydroxyfumarate exposure

1980 • 37 citations

Parallel efflux of Ca2+ and Pi in energized rat liver mitochondria

1981 • 35 citations

Uptake of Labeled Alloxan in Mouse Organs and Mitochondriain Vivoandin Vitro*

1983 • 35 citations

Influence of trace metals on alloxan cytotoxicity in pancreatic islets

1979 • 32 citations

Energy-dependent variation of thiol groups reactivity or accessibility in rat liver mitochondria, revealed by measurements of labelled thiol reagents incorporation

1976 • 24 citations

Effect of sulfhydryl reagents on permeability of toadfish islet tissue

1970 • 22 citations

Effects of alloxan and streptozotocin on calcium transport in isolated mouse liver mitochondria

1982 • 19 citations