Oxidative damage to mitochondria is mediated by the Ca2+-dependent inner-membrane permeability transition

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Quantitative Aspects of the Production of Superoxide Anion Radical by Milk Xanthine Oxidase

1970 • 1,037 citations

The oxidative inactivation of mitochondrial electron transport chain components and ATPase.

1990 • 718 citations

Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

1984 • 376 citations

Regulation of Ca ²⁺ release from mitochondria by the oxidation-reduction state of pyridine nucleotides

1978 • 364 citations

Action of cyclosporine on mitochondrial calcium fluxes

1987 • 329 citations

The role of catalytic superoxide formation in the O2 inhibition of nitroreductase

1975 • 306 citations

INACTIVATION OF OXIDATIVE AND PHOSPHORYLATIVE SYSTEMS IN MITOCHONDRIA BY PREINCUBATION WITH PHOSPHATE AND OTHER IONS

1955 • 277 citations

Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondrial damage.

1986 • 258 citations

Mechanisms of cell death

1989 • 237 citations

Membrane protein thiol cross-linking associated with the permeabilization of the inner mitochondrial membrane by Ca2+ plus prooxidants.

1990 • 198 citations

The calcium cycle of mitochondria

1979 • 197 citations

Respiratory Activity of Isolated Rat Brain Mitochondria followingin vitroExposure to Oxygen Radicals

1983 • 181 citations

The reversible Ca2+-induced permeabilization of rat liver mitochondria

1986 • 174 citations

A heart mitochondrial Ca2+-dependent pore of possible relevance to re-perfusion-induced injury. Evidence that ADP facilitates pore interconversion between the closed and open states

1990 • 168 citations

Mitochondrial damage as a mechanism of cell injury in the killing of cultured hepatocytes by tert-butyl hydroperoxide

1989 • 127 citations

Reoxygenation-dependent decrease in mitochondrial NADH:CoQ reductase (Complex I) activity in the hypoxic/reoxygenated rat heart

1991 • 126 citations

Cyclosporin A protects hepatocytes subjected to high Ca²⁺ and oxidative stress

1992 • 96 citations

Partial inhibition by cyclosporin A of the swelling of liver mitochondria in vivo and in vitro induced by sub-micromolar [Ca2+], but not by butyrate. Evidence for two distinct swelling mechanisms

1990 • 88 citations

Antibiotics as Tools for Metabolic Studies. VIII. Effect of Nonactin Homologs on Alkali Metal Cation Transport and Rate of Respiration in Mitochondria^*

1967 • 82 citations

‘Pore’ formation is not required for the hydroperoxide-induced Ca2+ release from rat liver mitochondria

1992 • 65 citations

Mitochondrial damage and its role in causing hepatocyte injury during stimulation of lipid peroxidation by iron nitriloacetate

1992 • 64 citations

Competitive Inhibition by Myoglobin of the Reduction of Cytochrome c by Xanthine Oxidase

1962 • 64 citations

Altered hepatic mitochondrial fatty acid oxidation and ketogenesis in endotoxic rats

1990 • 51 citations

Superoxide anion increases intracellular free calcium in human myometrial cells.

1990 • 49 citations

The involvement of cyclosporin A binding proteins in regulating and uncoupling mitochondrial energy transduction

1992 • 46 citations

The involvement of cyclosporin A binding proteins in regulating and uncoupling mitochondrial energy transduction

1992 • 37 citations

The effect of ferric iron complex on isolated rat liver mitochondria. I. Respiratory and electrochemical responses

1985 • 37 citations

Peroxidative injury of the mitochondrial respiratory chain during reperfusion of hypothermic rat liver

1987 • 35 citations

Methods of Biochemical Analysis

1973 • 28 citations

[58] Hydroperoxide effects on redox state of pyridine nucleotides and Ca2+ retention by mitochondria

1984 • 22 citations

Respiratory activity of isolated rat liver mitochondria following in vitro exposure to oxygen species: A threshold study

1990 • 19 citations

Nitrofurantoin inhibition of mouse liver mitochondrial respiration involving NAD-linked substrates

1986 • 18 citations