Dialectics in carrier research: The ADP/ATP carrier and the uncoupling protein

The Enzymes of Biological Membranes

1985 • 1,362 citations

Regulation of Metabolic Processes in Mitochondria

1967 • 1,182 citations

Keilin's Respiratory Chain Concept and Its Chemiosmotic Consequences

1979 • 727 citations

Metabolite Transport in Mitochondria

1979 • 618 citations

Molecular model of the action potential sodium channel.

1986 • 525 citations

Adenine Nucleotide Translocation of Mitochondria

1968 • 417 citations

Brown‐Adipose‐Tissue Mitochondria: Photoaffinity Labelling of the Regulatory Site of Energy Dissipation

1978 • 400 citations

The uncoupling protein from brown fat mitochondria is related to the mitochondrial ADP/ATP carrier. Analysis of sequence homologies and of folding of the protein in the membrane.

1985 • 360 citations

Dynamics of energy‐transducing membranes

1975 • 348 citations

Internal sequence repeats and the path of polypeptide in mitochondrial ADP/ATP translocase

1982 • 310 citations

ADP/ATP carrier protein from beef heart mitochondria has high amounts of tightly bound cardiolipin, as revealed by phosphorus-31 nuclear magnetic resonance

1985 • 296 citations

Mechanism and evolution of the uncoupling protein of brown adipose tissue

1990 • 270 citations

Aspartic acids 96 and 85 play a central role in the function of bacteriorhodopsin as a proton pump.

1989 • 259 citations

Molecular aspects of the adenine nucleotide carrier from mitochondria

1989 • 235 citations

Purification of the carboxy‐atractylate binding protein from mitochondria

1975 • 231 citations

Metabolite transport in mitochondria: an example for intracellular membrane function.

1970 • 229 citations

Solute carriers involved in energy transfer of mitochondria form a homologous protein family

1987 • 222 citations

Achievements and perspectives of mitochondrial research

1987 • 221 citations

Characteristics of the isolated purine nucleotide binding protein from brown fat mitochondria

1982 • 211 citations

Relation between the Gradient of the ATP/ADP Ratio and the Membrane Potential across the Mitochondrial Membrane

1977 • 210 citations

Achievements and perspectives of mitochondrial research

1985 • 210 citations

A third ADP/ATP translocator gene in yeast.

1990 • 205 citations

Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane.

1986 • 202 citations

Adenine Nucleotide Translocation of Mitochondria

1970 • 193 citations

Unspecific permeation and specific exchange of adenine nucleotides in liver mitochondria

1965 • 191 citations

Brown‐adipose‐tissue mitochondria: the regulation of the 32 000‐M_r uncoupling protein by fatty acids and purine nucleotides

1983 • 183 citations

The ADP-ATP Carrier in Mitochondrial Membranes

1976 • 181 citations

Molecular weight and hydrodynamic parameters of the adenosine 5'-diphosphate-adenosine 5'-triphosphate carrier in Triton X-100

1980 • 177 citations

Dynamics of energy-transducing membranes

1974 • 175 citations

Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. Isolation and analysis of AAC2.

1988 • 173 citations

The Utilization of Binding Energy in Coupled Vectorial Processes

1980 • 166 citations

The reconstituted isolated uncoupling protein is a membrane potential driven H+ translocator.

1985 • 163 citations

Complete amino acid sequence of the ADP/ATP carrier from beef heart mitochondria.

1982 • 144 citations

Endogenous ADP of mitochondria, an early phosphate acceptor of oxidative phosphorylation as disclosed by kinetic studies with C14 labelled ADP and ATP and with atractyloside

1965 • 136 citations

KURZMITTEILUNG

1982 • 135 citations

Isolation of the ADP, ATP carrier as the carboxyatractylate · protein complex from mitochondria

1978 • 134 citations

Site-directed Mutagenesis of the Yeast Mitochondrial ADP/ATP Translocator

1993 • 113 citations

Reconstitution of adenine nucleotide transport from beef heart mitochondria

1979 • 110 citations

The uncoupling protein from brown adipose tissue mitochondria is a dimer. A hydrodynamic study

1980 • 109 citations

Modulation of the reconstituted adenine nucleotide exchange by membrane potential

1980 • 93 citations

Demonstration of the relation between the adenine nucleotide carrier and the structural changes of mitochondria as induced by adenosine 5'-diphosphate

1974 • 92 citations

Structure-function studies of adenine nucleotide transport in mitochondria. II. Biochemical analysis of distinct AAC1 and AAC2 proteins in yeast.

1990 • 90 citations

Some Principle Effects of Bongkrekic Acid on the Binding of Adenine Nucleotides to Mitochondrial Membranes

1972 • 89 citations

Mapping of the nucleotide-binding sites in the ADP/ATP carrier of beef heart mitochondria by photolabeling with 2-azido[.alpha.-32P]adenosine diphosphate

1988 • 85 citations

Electrical imbalance of adenine nucleotide transport across the mitochondrial membrane.

1978 • 85 citations

On the Mechanism of Bongkrekate Effect on the Mitochondrial Adenine‐Nucleotide Carrier as Studied through the Binding of ADP

1973 • 81 citations

The transmembrane arrangement of the ADP/ATP carrier as elucidated by the lysine reagent pyridoxal 5‐phosphate

1986 • 80 citations

Binding of guanine nucleotides to the outer surface of the inner membrane of guinea pig brown fat mitochondria in correlation with the thermogenic activity of the tissue

1976 • 79 citations

Electrophoretic control of reconstituted adenine nucleotide translocation

1982 • 75 citations

Isolation of the ADP/ATP Translocator from Beef Heart Mitochondria as the Bongkrekate‐Protein Complex

1978 • 73 citations

Orientation of the N-terminal region of the membrane-bound ADP/ATP carrier protein explored by antipeptide antibodies and an arginine-specific endoprotease. Evidence that the accessibility of the N-terminal residues depends on the conformational state of the carrier

1989 • 72 citations

The ADP/ATP Carrier in Mitochondrial Membranes

1985 • 70 citations

Chapter 16 Metabolite carriers in mitochondria

1992 • 68 citations

Structure-function studies of adenine nucleotide transport in mitochondria. I. Construction and genetic analysis of yeast mutants encoding the ADP/ATP carrier protein of mitochondria.

1990 • 63 citations

Principles of Carrier Catalysis Elucidated by Comparing Two Similar Membrane Translocators from Mitochondria, the ADP/ATP Carrier and the Uncoupling Protein^a

1985 • 61 citations

Photoaffinity labeling of the nucleotide‐binding site of the uncoupling protein from hamster brown adipose tissue

1992 • 57 citations

Molecular mechanisms of transport

1992 • 57 citations

Sequences Required for Delivery and Localization of the ADP/ATP Translocator to the Mitochondrial Inner Membrane

1986 • 56 citations

Reconstitution of inhibitor binding properties of the isolated adenosine 5'-diphosphate,adenosine 5'-triphosphate carrier-linked binding protein

1977 • 51 citations

Labeling of two different regions of the nucleotide binding site of the uncoupling protein from brown adipose tissue mitochondria with two ATP-analogs

1992 • 50 citations

Effect of bongkrekic acid on the adenine nucleotide carrier in mitochondria: Tightening of adenine nucleotide binding and differentiation between inner and outer sites

1970 • 49 citations

The ADP/ATP carrier from yeast (AAC‐2) is uniquely suited for the assignment of the binding center by photoaffinity labeling

1989 • 47 citations

In the uncoupling protein from brown adipose tissue the C‐terminus protrudes to the c‐side of the membrane as shown by tryptic cleavage

1987 • 46 citations

Function-based Mapping of the Yeast Mitochondrial ADP/ATP Translocator by Selection for Second Site Revertants

1993 • 37 citations

Interaction of phospholipids with the detergent-solubilized ADP/ATP carrier protein as studied by spin-label electron spin resonance

1988 • 35 citations

Structure-function of the ADP/ATP carrier

1992 • 32 citations

Hunting for the pore of voltage-gated channels

1992 • 23 citations

Localization of immunoreactive regions in the beef heart adenine nucleotide carrier using rabbit antisera against the carboxyatractyloside-liganded and the sodium dodecyl sulfate denatured carrier forms

1986 • 15 citations

New trends in biological chemistry

1992 • 7 citations

Energy Transfer in Solute Carrier Transport

1987 • 3 citations