Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.

1988 • 846 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 826 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 751 citations

Relationship between configuration, function, and permeability in calcium-treated mitochondria.

1976 • 610 citations

Clinical Pharmacokinetics of Cyclosporin

1986 • 488 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 442 citations

The inhibition of mitochondrial calcium transport by lanthanides and Ruthenium Red

1974 • 351 citations

Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria

1987 • 332 citations

Action of cyclosporine on mitochondrial calcium fluxes

1987 • 329 citations

The relationship between mitochondrial membrane permeability, membrane potential, and the retention of Ca2+ by mitochondria.

1980 • 288 citations

The role of glutathione in the retention of Ca2+ by liver mitochondria.

1984 • 223 citations

Biological Oxidoreductions

1964 • 221 citations

Cyclophilin: distribution and variant properties in normal and neoplastic tissues.

1986 • 214 citations

Intramitochondrial phospholipase activity and the effects of Ca2+ plus N-ethylmaleimide on mitochondrial function.

1979 • 189 citations

The reversible Ca2+-induced permeabilization of rat liver mitochondria

1986 • 174 citations

Molecular architecture of the inner membrane of mitochondria from rat liver: a combined biochemical and stereological study.

1986 • 163 citations

Effects of phospholipase A2 inhibitors on ruthenium red-induced Ca2+ release from mitochondria.

1985 • 160 citations

N-acylation of ethanolamine phospholipids in canine myocardium

1982 • 138 citations

The Role of Phosphate in the Regulation of the Independent Calcium‐Efflux Pathway of Liver Mitochondria

1982 • 124 citations

N-Acylethanolamine phospholipid metabolism in normal and ischemic rat brain

1986 • 111 citations

Increased permeability of mitochondria during Ca2+ release induced by t-butyl hydroperoxide or oxalacetate. the effect of ruthenium red.

1982 • 109 citations

Mitochondrial calcium release as induced by Hg2+.

1988 • 106 citations

Influence of cyclosporin A on the respiration of isolated rat kidney mitochondria

1985 • 98 citations

The control of Ca2+ release from heart mitochondria.

1981 • 95 citations

Inhibition of permeability-dependent Ca2+ release from mitochondria by N-acylethanolamines, a class of lipids synthesized in ischemic heart tissue.

1982 • 91 citations

CYCLOPHILIN, A PRIMARY MOLECULAR TARGET FOR CYCLOSPORINE

1988 • 90 citations

Mitochondrial glutathione status during Ca2+ ionophore-induced injury to isolated hepatocytes

1988 • 83 citations

EGTA inhibits reverse uniport-dependent Ca2+ release from uncoupled mitochondria. Possible regulation of the Ca2+ uniporter by a Ca2+ binding site on the cytoplasmic side of the inner membrane.

1988 • 81 citations

Relationships between Ca2+ release, Ca2+ cycling, and Ca2+-mediated permeability changes in mitochondria.

1985 • 65 citations

Effects of N-ethylmaleimide on the limited uptake of Ca2+, Mn2+, and Sr2+ by rat liver mitochondria.

1978 • 62 citations

Reye's syndrome: Mitochondrial swelling and Ca2+ release induced by Reye's plasma, allantoin, and salicylate

1986 • 50 citations

Ruthenium red-sensitive and -insensitive release of Ca2+ from uncoupled heart mitochondria

1983 • 49 citations

Quantification of lysophosphatidylethanolamine in the nanomole range.

1981 • 47 citations

The entrapment of the Ca2+ indicator arsenazo III in the matrix space of rat liver mitochondria by permeabilization and resealing. Na+-dependent and -independent effluxes of Ca2+ in arsenazo III-loaded mitochondria

1986 • 42 citations

The mechanism of lead-induced mitochondrial Ca2+ efflux

1987 • 39 citations

Activation of adrenal cortex mitochondrial malic enzyme by Ca²⁺and Mg²⁺ ions

1975 • 38 citations

Some effects of Ca2+, Mg2+, and Mn2+ on the ultrastructure, light-scattering properties, and malic enzyme activity of adrenal cortex mitochondria

1976 • 36 citations

The effect of Ca2+ and acyl coenzyme A:lysophospholipid acyltransferase inhibitors on permeability properties of the liver mitochondrial inner membrane.

1986 • 34 citations

Calcium and magnesium ion losses in response to stimulants of efflux applied to heart, liver and kidney mitochondria

1981 • 28 citations

Oxaloacetate- and acetoacetate-induced calcium efflux from mitochondria occurs by reversal of the uptake pathway

1982 • 27 citations

Effects of lysophospholipids on Ca2+ transport in rat liver mitochondria incubated at physiological Ca2+ concentrations in the presence of Mg2+, phosphate and ATP at 37° C

1984 • 26 citations

Ruthenium red-induced loss of matrix K+ from uncoupled heart mitochondria

1982 • 9 citations

Regulation of the monovalent cation permeability of brain mitochondria

1982 • 5 citations

Some Actions of Purified Toxins from Bungarus fasciatus Venom on Isolated Pig‐Heart Mitochondria

1975 • 5 citations

Effects of amiprophosmethyl on massive and limited calcium loading of maize mitochondria

1983 • 4 citations