The Simian Retroviruses SIV and SRV

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex

1987 • 3,000 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1993 • 1,822 citations

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1991 • 1,613 citations

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

1993 • 1,450 citations

A TH1→TH2 switch is a critical step in the etiology of HIV infection

1993 • 1,403 citations

Zidovudine in Asymptomatic Human Immunodeficiency Virus Infection

1990 • 1,288 citations

A double‐blind, placebo‐controlled trial

1986 • 1,281 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

High Levels of HIV-1 in Plasma During All Stages of Infection Determined By Competitive PCR

1993 • 1,263 citations

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.

1986 • 1,242 citations

The Immunopathogenesis of Human Immunodeficiency Virus Infection

1993 • 1,194 citations

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

1992 • 1,025 citations

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

1991 • 1,025 citations

CD8 ⁺ Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication

1986 • 1,010 citations

Identification of a putative second T-cell receptor

1986 • 980 citations

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

1988 • 936 citations

Isolation of T-Cell Tropic HTLV-III-Like Retrovirus from Macaques

1985 • 929 citations

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

1987 • 902 citations

Identification of the Envelope V3 Loop as the Primary Determinant of Cell Tropism in HIV-1

1991 • 871 citations

Pathogenesis of human immunodeficiency virus infection

1993 • 835 citations

The common mucosal immune system and current strategies for induction of immune responses in external secretions

1987 • 810 citations

An African primate lentivirus (SIVsmclosely related to HIV-2

1989 • 750 citations

Molecular Targets for AIDS Therapy

1990 • 736 citations

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1986 • 730 citations

Biologic Features of HIV-1 That Correlate with Virulence in the Host

1988 • 679 citations

The trans-activator gene of HTLV-III is essential for virus replication

1986 • 635 citations

Induction of AIDS-Like Disease in Macaque Monkeys with T-Cell Tropic Retrovirus STLV-III

1985 • 629 citations

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

1986 • 615 citations

Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids

1985 • 580 citations

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

1989 • 577 citations

Cellular Proteins Bound to Immunodeficiency Viruses: Implications for Pathogenesis and Vaccines

1992 • 570 citations

Pathogenesis of lentivirus infections

1986 • 558 citations

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1991 • 548 citations

Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses

1987 • 543 citations

AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6.

1990 • 500 citations

Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus

1992 • 496 citations

Human infection by genetically diverse SIVSM-related HIV-2 in West Africa

1992 • 496 citations

The HIV A (sor) gene product is essential for virus infectivity

1987 • 475 citations

Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals

1993 • 464 citations

High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates.

1990 • 461 citations

Pathogenesis of human immunodeficiency virus infection.

1993 • 455 citations

The natural history of the primates

1985 • 446 citations

Inhibition of Lymphocyte Proliferation by a Synthetic Peptide Homologous to Retroviral Envelope Proteins

1985 • 433 citations

A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes

1986 • 430 citations

Isolation of an HTLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabeys

1986 • 419 citations

A Formalin-Inactivated Whole SIV Vaccine Confers Protection in Macaques

1989 • 419 citations

Genetic organization of a chimpanzee lentivirus related to HIV-1

1990 • 418 citations

The Simian Immunodeficiency Viruses

1990 • 387 citations

The sor Gene of HIV-1 Is Required for Efficient Virus Transmission in Vitro

1987 • 365 citations

Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein.

1990 • 360 citations

Evolutionary Biology of the New World Monkeys and Continental Drift

1980 • 359 citations

Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.

1989 • 357 citations

Immunization of chimpanzees confers protection against challenge with human immunodeficiency virus.

1991 • 357 citations

Nucleotide sequence of Mason-Pfizer monkey virus: An immunosuppressive D-type retrovirus

1986 • 342 citations

Protection of Macaques Against SIV Infection by Subunit Vaccines of SIV Envelope Glycoprotein gp160

1992 • 340 citations

Sequence of simian immunodeficiency virus from African green monkey, a new member of the HIV/SIV group

1988 • 336 citations

The Complete Nucleotide Sequence of a Pathogenic Molecular Clone of Simian Immunodeficiency Virus

1990 • 335 citations

THE BIOCHEMISTRY OF AIDS

1991 • 332 citations

Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III

1986 • 325 citations

Vaccine protection against simian immunodeficiency virus infection.

1989 • 324 citations

Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding

1993 • 320 citations

Quantitative competitive polymerase chain reaction for accurate quantitation of HIV DNA and RNA species.

1993 • 319 citations

Unusually high frequencies of HIV-specific cytotoxic T lymphocytes in humans.

1989 • 318 citations

Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys).

1986 • 313 citations

Mutational analysis of the human immunodeficiency virus: the orf-B region down-regulates virus replication.

1987 • 310 citations

New Human T-Lymphotropic Retrovirus Related to Simian T-Lymphotropic Virus Type III (STLV-III _AGM )

1986 • 295 citations

Sequence of simian immunodeficiency virus and its relationship to the human immunodeficiency viruses

1987 • 288 citations

Isolation of simian immunodeficiency virus from african green monkeys and seroepidemiologic survey of the virus in various non‐human primates

1988 • 284 citations

Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac

1988 • 283 citations

CD4+ T Cells: Specificity and Function

1988 • 281 citations

C-Type Virus associated with Gibbon Lymphosarcoma

1972 • 281 citations

Biology and Pathogenesis of Lentiviruses

1989 • 281 citations

Genital mucosal transmission of simian immunodeficiency virus: animal model for heterosexual transmission of human immunodeficiency virus

1989 • 279 citations

Expression and Characterization of the Trans -Activator of HTLV-III/LAV Virus

1986 • 276 citations

A new virus in a spontaneous mammary tumor of a rhesus monkey.

1970 • 276 citations

A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator.

1988 • 270 citations

Serologic Identification and Characterization of a Macaque T-Lymphotropic Retrovirus Closely Related to HTLV-III

1985 • 265 citations

Protection Against Vaginal SIV Transmission with Microencapsulated Vaccine

1993 • 265 citations

Techniques in HIV Research

1990 • 263 citations

Infection of cynomolgus monkeys with a chimeric HIV-1/SIVmac virus that expresses the HIV-1 envelope glycoproteins.

1992 • 262 citations

Infectious C-type virus isolated from a baboon placenta

1974 • 261 citations

Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus

1991 • 257 citations

TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter

1990 • 253 citations

Identification of the Fusion Peptide of Primate Immunodeficiency Viruses

1989 • 250 citations

Receptor interference groups of 20 retroviruses plating on human cells

1990 • 249 citations

Human immunodeficiency virus type 1 negative factor is a transcriptional silencer.

1989 • 243 citations

Fine mapping of an immunodominant domain in the transmembrane glycoprotein of human immunodeficiency virus

1987 • 242 citations

Myristylation is required for intracellular transport but not for assembly of D-type retrovirus capsids

1987 • 241 citations

Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys

1991 • 238 citations

Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

1990 • 236 citations

Neutralization of Divergent HIV-1 Isolates by Conformation-Dependent Human Antibodies to Gp120

1991 • 235 citations

A New Type D Retrovirus Isolated from Macaques with an Immunodeficiency Syndrome

1984 • 235 citations

Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues

1990 • 234 citations

Simian AIDS: Isolation of a Type D Retrovirus and Transmission of the Disease

1984 • 234 citations

Seroepidemiologic survey of captive old‐world primates for antibodies to human and simian retroviruses, and isolation of a lentivirus from sooty mangabeys (Cercocebus atys)

1986 • 233 citations

Evolution of the primate lentiviruses: evidence from vpx and vpr.

1992 • 232 citations

The GAG precursor of simian immunodeficiency virus assembles into virus-like particles.

1989 • 232 citations

Necropsy Findings in Rhesus Monkeys Experimentally Infected with Cultured Simian Immunodeficiency Virus (SIV)/Delta

1988 • 232 citations

Isolation and partial characterization of an HIV-related virus occurring naturally in chimpanzees in Gabon

1989 • 231 citations

Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees

1990 • 230 citations

HIV infection does not require endocytosis of its receptor, CD4

1988 • 228 citations

Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor.

1989 • 227 citations

The Emergence of Simian/Human Immunodeficiency Viruses

1992 • 225 citations

Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals

1989 • 225 citations

Differential susceptibility to the acquired immunodeficiency syndrome retrovirus in cloned cells of human leukemic T-cell line Molt-4

1986 • 222 citations

Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages

1990 • 221 citations

Significance of premature stop codons in env of simian immunodeficiency virus

1989 • 220 citations

Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus

1993 • 220 citations

Animal models of AIDS

1989 • 219 citations

Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys

1993 • 218 citations

Sequence analysis and acute pathogenicity of molecularly cloned SIVSMM-PBj14

1990 • 218 citations

T Cell Activation Antigen, CD26, as a Cofactor for Entry of HIV in CD4 ⁺ Cells

1993 • 217 citations

Immunologic and pathologic manifestations of the infection of rhesus monkeys with simian immunodeficiency virus of macaques.

1990 • 215 citations

9-(2-phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys

1991 • 214 citations

Identification and Biologic Characterization of an Acutely Lethal Variant of Simian Immunodeficiency Virus from Sooty Mangabeys (SIV/SMM)

1989 • 211 citations

LAV Revisited: Origins of the Early HIV-1 Isolates from Institut Pasteur

1991 • 210 citations

Isolation of a lentivirus from a macaque with lymphoma: comparison with HTLV-III/LAV and other lentiviruses

1986 • 208 citations

Complex determinants of macrophage tropism in env of simian immunodeficiency virus

1992 • 208 citations

A Strategy for Prophylactic Vaccination Against HIV

1993 • 203 citations

A history of poliomyelitis.

1971 • 203 citations

Prevention of HIV-2 and SIVsm infection by passive immunization in cynomolgus monkeys

1991 • 202 citations

OMPHALOCELE AND RAISED ALPHAFETOPROTEIN IN AMNIOTIC-FLUID

1975 • 199 citations

Isolation of T-Lymphotropic Retrovirus Related to HTLV-III/LAV from Wild-Caught African Green Monkeys

1985 • 196 citations

CD8+ T cells inhibit HIV replication in naturally infected CD4+ T cells. Evidence for a soluble inhibitor.

1990 • 196 citations

Cellular Receptors and Viral Glycoproteins Involved in Retrovirus Entry

1993 • 193 citations

An AIDS-related cytotoxic autoantibody reacts with a specific antigen on stimulated CD4+ T cells

1987 • 191 citations

Nucleotide Sequence of SRV-1, a Type D Simian Acquired Immune Deficiency Syndrome Retrovirus

1986 • 188 citations

An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.

1990 • 186 citations

Absolute quantitation of viremia in human immunodeficiency virus infection by competitive reverse transcription and polymerase chain reaction

1992 • 185 citations

Species-specific diversity among simian immunodeficiency viruses from African green monkeys

1991 • 185 citations

Molecular characterization of gag proteins from simian immunodeficiency virus (SIVMne)

1988 • 185 citations

Early viral replication in the brain of SIV-infected rhesus monkeys.

1991 • 184 citations

Differential Effects of nef on HIV Replication: Implications for Viral Pathogenesis in the Host

1989 • 183 citations

Localization of simian immunodeficiency virus in the central nervous system of rhesus monkeys.

1991 • 177 citations

Derivation of neurotropic simian immunodeficiency virus from exclusively lymphocytetropic parental virus: pathogenesis of infection in macaques

1992 • 177 citations

Variation in simian immunodeficiency virus env is confined to V1 and V4 during progression to simian AIDS

1991 • 176 citations

Preliminary report: protection of cynomolgus macaques against simian immunodeficiency virus by fixed infected-cell vaccine

1990 • 174 citations

Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase.

1991 • 173 citations

Infection of Macaca nemestrina by Human Immunodeficiency Virus Type-1

1992 • 173 citations

Immunohistochemical localization of human and simian immunodeficiency viral antigens in fixed tissue sections.

1987 • 170 citations

Sequence comparisons of retroviral proteins: relative rates of change and general phylogeny.

1988 • 169 citations

Mutational analysis of the 5′ non-coding region of human immunodeficiency virus type 1: effects of secondary structure on translation.

1988 • 168 citations

Cognitive and Motor Impairments Associated with SIV Infection in Rhesus Monkeys

1992 • 168 citations

Comparison of simian immunodeficiency virus isolates

1988 • 168 citations

Cloning of HTLV-4 and its relation to simian and human immunodeficiency viruses

1987 • 167 citations

An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives.

1991 • 166 citations

Failure of Zidovudine Prophylaxis after Accidental Exposure to HIV-1

1990 • 165 citations

Isolation and characterization of simian immunodeficiency virus from mandrills in Africa and its relationship to other human and simian immunodeficiency viruses

1988 • 163 citations

Long-term Persistent Infection of Macaque Monkeys with the Simian Immunodeficiency Virus

1987 • 162 citations

EPIDEMIC OF ACQUIRED IMMUNODEFICIENCY IN RHESUS MONKEYS

1983 • 161 citations

A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus

1990 • 160 citations

Transcriptional but not translational regulation of HIV-1 by the tat gene product

1988 • 158 citations

Cytogenetics and Molecular Genetics of Malignant Gliomas and Medulloblastoma

1990 • 158 citations

Spectrum of disease in macaque monkeys chronically infected with SIV/SMM

1989 • 158 citations

Prospects for the control of AIDS by immunizing seropositive individuals

1987 • 157 citations

Suppression of simian immunodeficiency virus replication in vitro by CD8+ lymphocytes.

1988 • 157 citations

Inoculation of baboons and macaques with simian immunodeficiency virus/Mne, a primate lentivirus closely related to human immunodeficiency virus type 2

1988 • 156 citations

Distinct subsets of retroviruses encode dUTPase

1992 • 152 citations

A subset of γδ lymphocytes is increased during HIV-1 infection

1991 • 152 citations

Characterization of Exogenous Type D Retrovirus from a Fibroma of a Macaque with Simian AIDS and Fibromatosis

1984 • 146 citations

Infection of a Laboratory Worker with Simian Immunodeficiency Virus

1994 • 145 citations

Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein increases env incorporation into particles and fusogenicity and infectivity

1993 • 145 citations

Langerhans cells, macrophages and lymphocyte subsets in the cervix and vagina of rhesus macaques.

1992 • 144 citations

Restricted replication of simian immunodeficiency virus strain 239 in macrophages is determined by env but is not due to restricted entry

1993 • 143 citations

Induction of Mucosal and Systemic Immunity to a Recombinant Simian Immunodeficiency Viral Protein

1992 • 142 citations

Isolation and Characterization of a Novel Protein (X-ORF Product) from SIV and HIV-2

1988 • 141 citations

Spectrum of Morphologic Changes of Lymph Nodes from Patients with AIDS or AIDS-Related Complexes

1986 • 141 citations

Isolation of a simian immunodeficiency virus related to human immunodeficiency virus type 2 from a west African pet sooty mangabey

1991 • 136 citations

Enhancement of SIV Infection with Soluble Receptor Molecules

1990 • 136 citations

Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV

1990 • 136 citations

Vaccine Protection of Rhesus Macaques Against Simian Immunodeficiency Virus Infection

1990 • 135 citations

Simian immunodeficiency virus RNA is efficiently encapsidated by human immunodeficiency virus type 1 particles

1993 • 135 citations

HIV-1 TAT “activates” presynthesized RNA in the nucleus

1989 • 135 citations

Abrogation of lymphocyte blastogenesis by a feline leukaemia virus protein

1978 • 135 citations

Cytoplasmic localization of the HTLV-III 3′orf protein in cultured T cells

1986 • 134 citations

Vaccination of Vaccinia-Naive Adults with Human Immunodeficiency Virus Type 1 gp160 Recombinant Vaccinia Virus in a Blinded, Controlled, Randomized Clinical Trial

1992 • 134 citations

Macrophage-tropic variants of SIV are associated with specific AIDS-related lesions but are not essential for the development of AIDS.

1991 • 133 citations

Isolation and characterization of a new chimpanzee lentivirus (simian immunodeficiency virus isolate cpz-ant) from a wild-captured chimpanzee

1992 • 133 citations

AIDS and Other Manifestations of HIV Infection

2004 • 133 citations

Inactivated simian immunodeficiency virus vaccine failed to protect rhesus macaques from intravenous or genital mucosal infection but delayed disease in intravenously exposed animals

1990 • 131 citations

Mucosal immunity, HIV transmission, and AIDS.

1993 • 127 citations

Simian immunodeficiency virus from African green monkeys

1988 • 126 citations

Simian immunodeficiency viruses from central and western Africa: evidence for a new species-specific lentivirus in tantalus monkeys

1993 • 126 citations

Prevalence of antibodies to 3 retroviruses in a captive colony of macaque monkeys

1988 • 126 citations

Elevated vascular cell adhesion molecule-1 in AIDS encephalitis induced by simian immunodeficiency virus.

1992 • 126 citations

Nutrition, body condition, activity patterns, and parasitism of free‐ranging troops of olive baboons (Papio anubis) in Kenya

1989 • 120 citations

Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeys

1993 • 119 citations

Cell Fusion Activity of the Simian Immunodeficiency Virus Envelope Protein Is Modulated by the Intracytoplasmic Domain

1993 • 118 citations

Mechanism of genital transmission of SIV: A hypothesis based on transmission studies and the location of SIV in the genital tract of chronically infected female rhesus macaques

1992 • 117 citations

Inhibition of lymphoproliferation by a synthetic peptide with sequence identity to gp41 of human immunodeficiency virus type 1

1989 • 117 citations

Sequence relationships of type D retroviruses which cause simian acquired immunodeficiency syndrome

1987 • 117 citations

Simian Immunodeficiency Virus/Delta-Induced Immunodeficiency Disease in Rhesus Monkeys: Relation of Antibody Response and Antigenemia

1988 • 117 citations

The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage

1991 • 115 citations

Oncornavirus: Isolation From a Squirrel Monkey ( Saimiri sciureus ) Lung Culture

1977 • 113 citations

A naturally immunogenic virion-associated protein specific for HIV-2 and SIV

1988 • 113 citations

ANTIBODIES TO SIMIAN T-LYMPHOTROPIC RETROVIRUS TYPE III IN AFRICAN GREEN MONKEYS AND RECOGNITION OF STLV-III VIRAL PROTEINS BY AIDS AND RELATED SERA

1985 • 113 citations

AIDS and Other Manifestations of HIV Infection

1993 • 111 citations

Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species.

1989 • 111 citations

Cellular localization of simian immunodeficiency virus in lymphoid tissues. I. Immunohistochemistry and electron microscopy.

1989 • 110 citations

Protection of macaques with a simian immunodeficiency virus envelope peptide vaccine based on conserved human immunodeficiency virus type 1 sequences.

1991 • 109 citations

Simian immunodeficiency viruses from African green monkeys display unusual genetic diversity

1990 • 109 citations

The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1.

1992 • 108 citations

HIV infection of primate lymphocytes and conservation of the CD4 receptor

1987 • 107 citations

Isolation of a new serotype of simian acquired immune deficiency syndrome type D retrovirus from Celebes black macaques (Macaca nigra) with immune deficiency and retroperitoneal fibromatosis

1985 • 107 citations

Analysis of simian immunodeficiency virus sequence variation in tissues of rhesus macaques with simian AIDS

1993 • 106 citations

Alterations in potential sites for glycosylation predominate during evolution of the simian immunodeficiency virus envelope gene in macaques

1992 • 105 citations

In vitro growth characteristics of simian T-lymphotropic virus type III.

1985 • 104 citations

Effects of Initiation of 3'-Azido,3'-Deoxythymidine (Zidovudine) Treatment at Different Times after Infection of Rhesus Monkeys with Simian Immunodeficiency Virus

1993 • 104 citations

Identification of Two Neutralizing and 8 Non-Neutralizing Epitopes on Simian Immunodeficiency Virus Envelope Using Monoclonal Antibodies

1992 • 103 citations

Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein alters the conformation of the external domain

1994 • 103 citations

Protection in simian immunodeficiency virus-vaccinated monkeys correlates with anti-HLA class I antibody response.

1992 • 102 citations

Prevalence of natural infection with simian immunodeficiency virus and simian T-cell leukemia virus type I in a breeding colony of sooty mangabey monkeys

1990 • 101 citations

Pathologic Features of SIV-Induced Disease and the Association of Macrophage Infection with Disease Evolution

1992 • 101 citations

HIV with Multiple Gene Deletions as a Live Attenuated Vaccine for AIDS

1992 • 99 citations

A distinct African lentivirus from Sykes' monkeys

1993 • 99 citations

Recombinant Virus Vaccine-Induced SIV-specific CD8 ⁺ Cytotoxic T Lymphocytes

1991 • 99 citations

Truncations of the simian immunodeficiency virus transmembrane protein confer expanded virus host range by removing a block to virus entry into cells

1993 • 99 citations

Simian immunodeficiency virus (SIV) infection of infant rhesus macaques as a model to test antiretroviral drug prophylaxis and therapy: oral 3'-azido-3'-deoxythymidine prevents SIV infection

1992 • 98 citations

Simian virus 40-induced disease in rhesus monkeys with simian acquired immunodeficiency syndrome.

1992 • 98 citations

Lymphadenopathy in macaques experimentally infected with the simian immunodeficiency virus (SIV).

1987 • 97 citations

Analysis of Envelope Changes Acquired by SIVmac239 during Neuroadaption in Rhesus Macaques

1993 • 97 citations

Relationship of neurologic status in macaques infected with the simian immunodeficiency virus to cerebrospinal fluid quinolinic acid and kynurenic acid

1992 • 95 citations

Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein

1990 • 94 citations

CD8+ T lymphocyte control of HIV replication in cultured CD4+ cells varies among infected individuals

1989 • 93 citations

Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant

1993 • 92 citations

Retrovirus-induced murine motor neuron disease: mapping the determinant of spongiform degeneration within the envelope gene.

1989 • 92 citations

Replication of an acutely lethal simian immunodeficiency virus activates and induces proliferation of lymphocytes

1991 • 91 citations

Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac

1993 • 91 citations

Assembly of the Matrix Protein of Simian Immunodeficiency Virus into Virus-like Particles

1993 • 91 citations

Prevention of simian acquired immune deficiency syndrome with a formalin-inactivated type D retrovirus vaccine

1986 • 91 citations

Genetic and Biological Comparisons of Pathogenic and Nonpathogenic Molecular Clones of Simian Immunodeficiency Virus (SIV_MAC)

1992 • 91 citations

Responses of Infant Rhesus Monkeys to Inoculation With Mason-Pfizer Monkey Virus Materials<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1975 • 91 citations

Does the HIV envelope induce a chronic graft-versus-host-like disease?

1992 • 90 citations

Localization of SIV in the genital tract of chronically infected female rhesus macaques.

1992 • 89 citations

Malignant lymphomas in cynomolgus monkeys infected with simian immunodeficiency virus.

1990 • 88 citations

A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses

1990 • 88 citations

Retroperitoneal fibromatosis and acquired immunodeficiency syndrome in macaques. Pathologic observations and transmission studies.

1985 • 88 citations

Simian immunodeficiency virus infection of the gastrointestinal tract of rhesus macaques. Functional, pathological, and morphological changes.

1993 • 88 citations

The gag-specific cytotoxic T lymphocytes in rhesus monkeys infected with the simian immunodeficiency virus of macaques.

1990 • 87 citations

Arteriopathy in macaques infected with simian immunodeficiency virus

1992 • 87 citations

An idiotypic network model of AIDS immunopathogenesis.

1991 • 86 citations

Simian Immunodeficiency Virus Infection of Macaques: End-Stage Disease Is Characterized by Widespread Distribution of Proviral DNA in Tissues

1991 • 86 citations

A nuclear translational block imposed by the HIV-1 U3 region is relieved by the Tat-TAR interaction

1990 • 86 citations

Use of protein unfolding studies to determine the conformational and dimeric stabilities of HIV-1 and SIV proteases

1992 • 85 citations

Epstein‐barr virus‐related herpesvirus from a rhesus monkey (Macaca Mulatta) with malignant lymphoma

1986 • 85 citations

Intrarectal challenge of macaques vaccinated with formalin-inactivated simian immunodeficiency virus

1992 • 84 citations

Identification of a New Subgroup of SIVagm in Tantalus Monkeys

1993 • 84 citations

Effect of recombinant soluble CD4 in rhesus monkeys infected with simian immunodeficiency virus of macaques

1989 • 84 citations

Electrostatic interactions modulate the RNA-binding and transactivation specificities of the human immunodeficiency virus and simian immunodeficiency virus Tat proteins.

1993 • 84 citations

Immunodeficiency and Lymphoproliferative Disease in an African Green Monkey Dually Infected with SIV and STLV-I

1992 • 84 citations

CD8+ lymphocytes suppress HIV production by autologous CD4+ cells without eliminating the infected cells from culture

1990 • 83 citations

Rhesus Macaques Inoculated With Molecularly Cloned Simian Immunodeficiency Virus

1989 • 83 citations

Neurobiology of Simian and Feline Immunodeficiency Virus Infections

1991 • 82 citations

Pathogenesis of SIV_mac251 after atraumatic inoculation of the rectal mucosa in rhesus monkeys

1993 • 81 citations

Animal Models for Acquired Immunodeficiency Syndrome

1987 • 80 citations

Transmissible Lymphoma and Simian Acquired Immunodeficiency Syndrome in Rhesus Monkeys<xref ref-type="fn" rid="FN1">2</xref>

1986 • 80 citations

Isolation and characterization of a new type D retrovirus from the Asian primate, Presbytis obscurus (spectacled langur)

1978 • 79 citations

A highly divergent proviral DNA clone of SIV from a distinct species of african green monkey

1991 • 79 citations

New Concepts in AIDS Pathogenesis

1993 • 79 citations

Cell-Mediated Infection of Human Placental Trophoblast with HIV In Vitro

1991 • 78 citations

Plasma HIV-1 Viremia in HIV-1 Infected Individuals Assessed by Polymerase Chain Reaction

1992 • 78 citations

Studies on the Specificity of the Vaccine Effect Elicited by Inactivated Simian Immunodeficiency Virus

1993 • 77 citations

Secretory immune responses in the mouse vagina after parenteral or intravaginal immunization with an immunostimulating complex (ISCOM)

1991 • 77 citations

Immune response of rhesus macaques to recombinant simian immunodeficiency virus gp130 does not protect from challenge infection

1993 • 77 citations

Isolation from African Sykes' monkeys (Cercopithecus mitis) of a lentivirus related to human and simian immunodeficiency viruses

1991 • 77 citations

Production and of monoclonal antibodies to simian immunodeficiency virus envelope glycoproteins

1991 • 76 citations

Effect of Virus Dose and Nonoxynol‐9 on the Genital Transmission of SIV in Rhesus Macaques

1990 • 76 citations

Interference with human immunodeficiency virus (HIV) replication by CD8+ T cells in peripheral blood leukocytes of asymptomatic HIV carriers in vitro

1990 • 76 citations

Use of Simian Immunodeficiency Viruses for AIDS Research

1989 • 76 citations

The pathology of an epizootic of acquired immunodeficiency in rhesus macaques.

1984 • 75 citations

Functional comparison of transactivation by simian immunodeficiency virus from rhesus macaques and human immunodeficiency virus type 1

1988 • 75 citations

Mechanisms of Retrovirus Replication

1992 • 75 citations

Evolution of primate oncornaviruses: An endogenous virus from langurs ( Presbytis spp.) with related virogene sequences in other Old World monkeys

1977 • 74 citations

The resistance of HIV‐infected chimpanzees to progression to AIDS correlates with absence of HIV‐related T‐cell dysfunction

1993 • 74 citations

Infection of macaque monkeys with a chimeric human and simian immunodeficiency virus

1992 • 74 citations

Passively transferred antibodies directed against conserved regions of SIV envelope protect macaques from SIV infection

1993 • 74 citations

Micromethod for assaying reverse transcriptase of human T-cell lymphotropic virus type III/lymphadenopathy-associated virus

1987 • 73 citations

Simian lentiviruses — the SIV group

1988 • 73 citations

A new method for measuring reverse transcriptase activity by ELISA

1992 • 73 citations

The Origins of the AIDS Virus

1988 • 72 citations

Antibody-dependent enhancement of simian immunodeficiency virus (SIV) infection in vitro by plasma from SIV-infected rhesus macaques

1990 • 72 citations

Immunological studies of the basis for the apathogenicity of simian immunodeficiency virus from African green monkeys.

1990 • 72 citations

Vaccination of rhesus monkeys with synthetic peptide in a fusogenic proteoliposome elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes.

1992 • 71 citations

Incorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell line.

1991 • 70 citations

Cytotoxic T lymphocyte response against multiple simian immunodeficiency virusA (SIV) proteins in SIV-infected macaques.

1992 • 70 citations

Fusogenic activity of SIV (Simian Immunodeficiency Virus) peptides located in the GP32 NH2 terminal domain

1991 • 70 citations

Ultrastructural comparison of the retroviruses associated with human and simian acquired immunodeficiency syndromes.

1985 • 70 citations

Simian immunodeficiency viruses and their relationship to the human immunodeficiency viruses

1988 • 68 citations

Function of the human immunodeficiency virus types 1 and 2 Rev proteins is dependent on their ability to interact with a structured region present in env gene mRNA

1990 • 68 citations

Nonhuman Primate Models for Evaluation of AIDS Therapy^a

1990 • 67 citations

Structural role of the matrix protein of type D retroviruses in gag polyprotein stability and capsid assembly

1990 • 67 citations

Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC

1988 • 67 citations

Thymus in simian immunodeficiency virus-infected rhesus monkeys.

1991 • 67 citations

A cross sectional survey for B virus antibody in a colony of group housed rhesus macaques.

1990 • 66 citations

HIV-Related Lentiviruses of Nonhuman Primates

1989 • 65 citations

Isolation of human immunodeficiency virus-related simian immunodeficiency viruses from African green monkeys.

1989 • 65 citations

A highly divergent HIV-2-related isolate

1989 • 65 citations

CD4-Pseudomonas exotoxin hybrid protein blocks the spread of human immunodeficiency virus infection in vitro and is active against cells expressing the envelope glycoproteins from diverse primate immunodeficiency retroviruses.

1989 • 64 citations

Reduced Virus Load in Rhesus Macaques Immunized with Recombinant gp160 and Challenged with Simian Immunodeficiency Virus

1994 • 64 citations

Human immunodeficiency virus type 2 vpx protein augments viral infectivity

1991 • 64 citations

MAC-1, a new genetically transmitted type C virus of primates: “low frequency” activation from stumptail monkey cell cultures

1978 • 64 citations

Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines

1994 • 64 citations

Structure of simian immunodeficiency virus regulatory genes.

1989 • 64 citations

Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge.

1992 • 63 citations

Protection of macaques against simian AIDS by immunization with a recombinant vaccinia virus expressing the envelope glycoproteins of simian type D retrovirus.

1989 • 63 citations

Differences in transcriptional enhancers of HIV-1 and HIV-2. Response to T cell activation signals.

1990 • 63 citations

Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type III in monkeys with experimentally induced acquired immune deficiency-like syndrome.

1986 • 63 citations

Serial pathogenesis study of SIV brain infection.

1991 • 62 citations

Retroperitoneal fibromatosis and acquired immunodeficiency syndrome in macaques: clinical and immunologic studies.

1986 • 62 citations

Simian immunodeficiency virus needlestick accident in a laboratory worker

1992 • 62 citations

Cellular localization of simian immunodeficiency virus in lymphoid tissues. II. In situ hybridization.

1989 • 62 citations

Comparative Biology of Natural and Experimental SIVmac Infection in Macaque Monkeys: A Review

1990 • 62 citations

Infection of Rhesus and Cynomolgus Macaques with a Rapidly Fatal SIV (SIV_SMM/PBj) Isolate From Sooty Mangabeys

1992 • 61 citations

Simian immunodeficiency virus inhibits bone marrow hematopoietic progenitor cell growth

1990 • 61 citations

Simian retrovirus D serogroup 1 has a broad cellular tropism for lymphoid and nonlymphoid cells

1988 • 60 citations

Experimental infection of cynomolgus monkeys (Macaca fascicularis) with HIV-2.

1989 • 60 citations

Early SIV encephalopathy

1991 • 60 citations

Isolation and characterization of an ether glucuronide of zidovudine, a major metabolite in monkeys and humans.

1990 • 60 citations

Genetic analysis of simian virus 40 from brains and kidneys of macaque monkeys

1992 • 59 citations

Relation of HTLV-4 to simian and human immunodeficiency-associated viruses

1987 • 59 citations

Intracellular Transport and Virion Incorporation of vpx Requires Interaction with Other Virus Type-Specific Components

1993 • 59 citations

Purification and N-terminal amino acid sequence comparisons of structural proteins from retrovirus-D/Washington and Mason-Pfizer monkey virus

1985 • 59 citations

Selective infection of human CD4+ cells by simian immunodeficiency virus: productive infection associated with envelope glycoprotein-induced fusion.

1989 • 59 citations

Immunization with Tween-ether-treated SIV adsorbed onto aluminum hydroxide protects monkeys against experimental SIV infection

1992 • 58 citations

Simian immunodeficiency virus displays complex patterns of RNA splicing

1990 • 57 citations

The use of primers from highly conserved pol regions to identify uncharacterized retroviruses by the polymerase chain reaction

1990 • 57 citations

Outbreak of malignant lymphoma in rhesus monkeys.

1971 • 57 citations

Synthetic peptide in mineral oil adjuvant elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes in rhesus monkeys.

1993 • 57 citations

Gag precursors of HIV and SIV are cleaved into six proteins found in the mature virions.

1990 • 56 citations

Identification of viral determinants of macrophage tropism for simian immunodeficiency virus SIVmac

1991 • 56 citations

Formation of Lentivirus Particles by Mammalian Cells Infected with Recombinant Fowlpox Virus

1991 • 56 citations

Viremia, antigenemia, and serum antibodies in rhesus macaques infected with simian retrovirus type 1 and their relationship to disease course.

1987 • 55 citations

Efficacy of live‐attenuated and whole‐inactivated simian immunodeficiency virus vaccines against vaginal challenge with virulent SIV

1992 • 55 citations

Extensive genetic variability of simian immunodeficiency virus from African green monkeys

1989 • 55 citations

Clinical features and predictive markers of disease progression in cynomolgus monkeys experimentally infected with simian immunodeficiency virus

1992 • 55 citations

Effect of Zidovudine on Serum Human Immunodeficiency Virus Core Antigen Levels

1988 • 55 citations

Zidovudine Resistance of Human Immunodeficiency Virus

1990 • 55 citations

Nonhuman Primate Retrovirus Isolates and AIDS

1988 • 55 citations

Isolation of a type D retrovirus from B-cell lymphomas of a patient with AIDS

1991 • 54 citations

Correlates of SIV encephalitis in rhesus monkeys

1992 • 54 citations

Induction of simian acquired immune deficiency syndrome (SAIDS) with a molecular clone of a type D SAIDS retrovirus

1987 • 54 citations

Molecularly cloned simian immunodeficiency virus SIVagm3 is highly divergent from other SIVagm isolates and is biologically active in vitro and in vivo

1989 • 54 citations

Evolutionary Potential of Complex Retroviruses

1992 • 54 citations

Immunophenotypic characterization of the cutaneous exanthem of SIV-infected rhesus monkeys. Apposition of degenerative Langerhans cells and cytotoxic lymphocytes during the development of acquired immunodeficiency syndrome.

1987 • 54 citations

Vaccinia virus recombinants expressing chimeric proteins of human immunodeficiency virus and gamma interferon are attenuated for nude mice.

1992 • 53 citations

Isolation and Characterization of Simian Immunodeficiency Viruses from Two Subspecies of African Green Monkeys

1990 • 53 citations

Simian immunodeficiency virus is restricted to a subset of blood CD4+ lymphocytes that includes memory cells.

1990 • 53 citations

Studies of cloned simian immunodeficiency virus-specific T lymphocytes. gag-specific cytotoxic T lymphocytes exhibit a restricted epitope specificity.

1990 • 53 citations

Development of simian immunodeficiency virus isolation, titration, and neutralization assays which use whole blood from rhesus monkeys and an antigen capture enzyme-linked immunosorbent assay

1991 • 52 citations

CD8+CD4- lymphocyte lines can harbor the AIDS virus in vitro.

1989 • 52 citations

Decline in the CD4⁺Lymphocyte Population in the Blood of SIV-Infected Macaques Is Not Reflected in Lymph Nodes

1993 • 52 citations

Conserved T-cell receptor repertoire in simian immunodeficiency virus-infected rhesus monkeys.

1993 • 52 citations

Inhibition of cellular activation of retroviral replication by CD8+ T cells derived from non-human primates

1993 • 51 citations

Immunodeficiency in Rhesus Monkeys Associated With the Original Mason-Pfizer Monkey Virus<xref ref-type="fn" rid="FN2">2</xref>

1986 • 51 citations

Transmission of Simian Acquired Immunodeficiency Syndrome (SAIDS) with Blood or Filtered Plasma

1984 • 51 citations

Natural History of Endemic Type D Retrovirus Infection and Acquired Immune Deficiency Syndrome in Group-Housed Rhesus Monkeys<xref ref-type="fn" rid="FN1">2</xref>

1987 • 51 citations

Persistent infection of baboons and Rhesus monkeys with different strains of HIV-2

1991 • 51 citations

Quantitation of a lentivirus in its natural host: simian immunodeficiency virus in African green monkeys

1992 • 51 citations

Detection of HIV-1 Distribution in Different Blood Fractions by Two Nucleic Acid Amplification Assays

1993 • 50 citations

Evaluation of Human and Simian Immunodeficiency Virus Plaque and Neutralization Assays

1989 • 50 citations

EXPERIMENTAL TRANSMISSION OF SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME (SAIDS) AND KAPOSI-LIKE SKIN LESIONS

1983 • 50 citations

Cellular factors regulate transactivation of human immunodeficiency virus type 1

1991 • 50 citations

Pathogenesis of simian AIDS in rhesus macaques inoculated with the SRV-1 strain of type D retrovirus.

1986 • 50 citations

Human Retroviruses: HTLV-I and HTLV-II

1993 • 49 citations

Population Sequence Analysis of a Simian Immunodeficiency Virus (32H Reisolate of SIV_mac251): A Virus Stock Used for International Vaccine Studies

1992 • 49 citations

Construction and characterization of an infectious DNA clone and of mutants of simian immunodeficiency virus isolated from the African green monkey

1990 • 49 citations

Distribution of type D retrovirus sequences in tissues of macaques with simian acquired immune deficiency and retroperitoneal fibromatosis

1986 • 49 citations

Immunological cross reactivity of Mason–Pfizer monkey virus with type C RNA viruses endogenous to primates

1976 • 49 citations

Clinical features of simian acquired immunodeficiency syndrome (SAIDS) in rhesus monkeys.

1984 • 49 citations

Specific and non-specific immunity and protection of macaques against SIV infection

1992 • 49 citations

In vitro macrophage tropism of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac)

1991 • 49 citations

Serial pathogenesis study of SIV brain infection

1991 • 48 citations

Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease

1991 • 48 citations

Evidence for a lentiviral etiology in an epizootic of immune deficiency and lymphoma in stump‐tailed macaques (Macaca arctoides)

1992 • 48 citations

Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus env proteins possess a functionally conserved assembly domain

1990 • 48 citations

Soluble CD4 enhances simian immunodeficiency virus SIVagm infection

1990 • 48 citations

Human and Simian Immunodeficiency Retroviruses: Activation and Differential Transactivation of Gene Expression

1988 • 48 citations

SIMIAN TUBERCULOSIS: IMMUNOLOGIC ASPECTS*

1968 • 48 citations

Genetic differences accounting for evolution and pathogenicity of simian immunodeficiency virus from a sooty mangabey monkey after cross-species transmission to a pig-tailed macaque

1992 • 47 citations

The Human Immunodeficiency Virus Type 2 (HIV-2) Contains a Novel Gene Encoding a 16 kD Protein Associated with Mature Virions

1988 • 47 citations

Characterization of clones of HIV-1 infected HuT 78 cells defective in gag gene processing and of SIV clones producing large amounts of envelope glycoprotein.

1990 • 47 citations

Computer emulation of thin section electron microscopy predicts an envelope-associated icosadeltahedral capsid for human immunodeficiency virus.

1988 • 46 citations

Antiviral effects of 3'-fluorothymidine and 3'-azidothymidine in cynomolgus monkeys infected with simian immunodeficiency virus.

1991 • 46 citations

Analysis of the function of viral protein X (VPX) of HIV-2

1989 • 46 citations

[IMMUNITY TO CANCER].

1964 • 46 citations

Distribution of a macaque immunosuppressive type D retrovirus in neural, lymphoid, and salivary tissues

1988 • 46 citations

Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS

1993 • 46 citations

A capture enzyme immunoassay for detection of HIV-2/SIV antigen.

1991 • 45 citations

Detection of human immunodeficiency virus type 1 genomic RNA in plasma samples by reverse‐transcription polymerase chain reaction

1991 • 45 citations

Polyclonal B-cell activation reveals antibodies against human immunodeficiency virus type 1 (HIV-1) in HIV-1-seronegative individuals.

1990 • 45 citations

Relocation of a protease-like gene segment between two retroviruses.

1987 • 45 citations

Transmembrane envelope glycoproteins of human immunodeficiency virus type 2 and simian immunodeficiency virus SIV-mac exist as homodimers

1990 • 45 citations

Strain-specific neutralizing determinant in the transmembrane protein of simian immunodeficiency virus

1991 • 45 citations

SIV from stump-tailed macaques: Molecular characterization of a highly transmissible primate lentivirus

1992 • 45 citations

Simian immunodeficiency virus induces expression of class II major histocompatibility complex structures on infected target cells in vitro

1987 • 45 citations

Development of vivo of genetic variability of simian immunodeficiency virus.

1991 • 45 citations

3′-Azido-2′,3′-Dideoxyuridine (AzddU): Comparative Pharmacokinetics with 3′-Azido-3′-Deoxythymidine (AZT) in Monkeys

1990 • 45 citations

Cloning and sequences of primate CD4 molecules: Diversity of the cellular receptor for simian immunodeficiency virus/human immunodeficiency virus

1992 • 44 citations

Protection of monkeys by a split vaccine against SIVmac depends upon biological properties of the challenge virus

1993 • 43 citations

Inapparent Carriers of Simian Acquired Immune Deficiency Syndrome Type D Retrovirus and Disease Transmission With Saliva<xref ref-type="fn" rid="FN1">2</xref>

1986 • 43 citations

Gag Precursors of HIV and SIV Are Cleaved Into Six Proteins Found in the Mature Virions

1990 • 43 citations

Prevalence of Antibodies to SIV in Baboons in Their Native Habitat

1989 • 42 citations

Malignant Lymphoma Associated with Human AIDS and with SIV-Induced Immunodeficiency in Macaques

1992 • 42 citations

Localization of the receptor gene for type D simian retroviruses on human chromosome 19

1990 • 41 citations

The Use of SIV-Infected Rhesus Monkeys for the Preclinical Evaluation of AIDS Drugs and Vaccines

1992 • 41 citations

Complete nucleotide sequence of a simian immunodeficiency virus from African green monkeys: A novel type of intragroup divergence

1990 • 41 citations

Isolation and characterization of simian immunodeficiency virus from African white-crowned mangabey monkeys (Cercocebus torquatus lunulatus)

1993 • 41 citations

Simian immunodeficiency virus infection via amniotic fluid: a model to study fetal immunopathogenesis and prophylaxis.

1993 • 41 citations

Feline Oncoretroviruses

1993 • 41 citations

Shared antigenic epitopes of the major core proteins of human and simian immunodeficiency virus isolates

1992 • 40 citations

Lentivirus-induced Pulmonary Lesions in Rhesus Monkeys (Macaca mulatta) Infected with Simian Immunodeficiency Virus

1991 • 40 citations

Identification of a Neutralizing Domain in the External Envelope Glycoprotein of Simian Immunodeficiency Virus

1992 • 40 citations

T-cell activation influences initial DNA synthesis of simian immunodeficiency virus in resting T lymphocytes from macaques

1993 • 40 citations

Molecular Clones of SIV_sm and SIV_agm: Experimental Infection of Macaques and African Green Monkeys

1990 • 39 citations

Endogenous New World primate type C viruses isolated from owl monkey (Aotus trivirgatus) kidney cell line.

1978 • 38 citations

Maternal transmission of SIV_smm in rhesus macaques

1991 • 38 citations

Comparison of Linear Antigenic Sites in the Envelope Proteins of Human Immunodeficiency Virus (HIV) Type 2 and Type 1

1991 • 37 citations

Coexpression of the simian immunodeficiency virus Env and Rev proteins by a recombinant human adenovirus host range mutant

1992 • 37 citations

A PCR-based strategy for extensive mutagenesis of a target DNA sequence.

1993 • 37 citations

Characterization of Clones of HIV‐1 Infected HuT 78 Cells Defective in gag Gene Processing and of SIV Clones Producing Large Amounts of Envelope Glycoprotein

1990 • 37 citations

Pathogenesis of Acute Infection in Rhesus Macaques with a Lymphocyte-Tropic Strain of Simian Immunodeficiency Virus

1992 • 36 citations

Change of nipple preference between successive offspring in Japanese macaques

1989 • 36 citations

Maternal–fetal transmission of SIV in macaques: Disseminated adenovirus infection in an offspring with congenital SIV infection

1991 • 36 citations

Simian Acquired Immunodeficiency Syndrome

1986 • 36 citations

Patterns of Antibody Recognition of Selected Conserved Amino Acid Sequences from the HIV Envelope in Sera from Different Stages of HIV Infection

1989 • 36 citations

Vpx of simian immunodeficiency virus is localized primarily outside the virus core in mature virions

1993 • 36 citations

Productive infection of both CD4+ and CD4− human cell lines with HIV-1, HIV-2 and SIVagm

1990 • 36 citations

Compatibility of rev gene activity in the four groups of primate lentiviruses

1991 • 35 citations

Two distinct lymphocyte populations mediate simian immunodeficiency virus envelope-specific target cell lysis.

1990 • 35 citations

Genetic Analysis of a New Subgroup of Human and Simian T-Lymphotropic Retroviruses: HTLV-IV, LAV-2, SBL-6669, and STLV-III_AGM

1987 • 35 citations

An immunohistologic study of granulomatous inflammation in SIV-infected rhesus monkeys

1993 • 35 citations

Selective replication of simian immunodeficiency virus in a subset of CD4+ lymphocytes.

1989 • 35 citations

Studies of the conformation-dependent neutralizing epitopes of simian immunodeficiency virus envelope protein

1994 • 34 citations

Complement-mediated, infection-enhancing antibodies in plasma from vaccinated macaques before and after inoculation with live simian immunodeficiency virus

1990 • 34 citations

A highly divergent simian immunodeficiency virus (SIVstm) recovered from stored stump-tailed macaque tissues

1991 • 34 citations

Histopathological changes in simian immunodeficiency virus infection

1990 • 33 citations

Generation and characterization of infectious chimeric clones between human immunodeficiency virus type 1 and simian immunodeficiency virus from an African green monkey

1990 • 33 citations

The Morphology of Simian Immunodeficiency Virus as Shown by Negative Staining Electron Microscopy

1989 • 33 citations

Functional and Immunological Characterization of SIV Envelope Glycoprotein Produced in Genetically Engineered Mammalian Cells

1991 • 33 citations

Reticuloendotheliosis type C and primate type D oncoretroviruses are members of the same receptor interference group

1992 • 33 citations

An Epitope on the Surface Envelope Glycoprotein (gp130) of Simian Immunodeficiency Virus (SIV_mac) Involved in Viral Neutralization and T Cell Activation

1993 • 32 citations

Improved Detection of HIV-2 DNA in Clinical Samples Using a Nested Primer-Based Polymerase Chain Reaction

1992 • 32 citations

Molecular Characterization and Comparison of Simian Immunodeficiency Virus Isolates From Macaques, Mangabeys, and African Green Monkeys

1989 • 32 citations

Target cells during early SIV encephalopathy

1993 • 32 citations

In VivoAdministration to Rhesus Monkeys of a CD4-Specific Monoclonal Antibody Capable of Blocking AIDS Virus Replication

1993 • 32 citations

Sustained increases in cerebrospinal fluid quinolinic acid concentrations in rhesus macaques (Macaca mulatta) naturally infected with simian retrovirus type-D

1990 • 32 citations

The use of the polymerase chain reaction for the detection of Simian immunodeficiency virus in experimentally infected macaques

1990 • 32 citations

Molecular characterization and comparison of simian immunodeficiency virus isolates from macaques, mangabeys, and African green monkeys.

1989 • 32 citations

Disposition in animals of a new anti-HIV agent: 2',3'-didehydro-3'-deoxythymidine.

1990 • 31 citations

Suppression of HIV-1 Reverse Transcriptase Activity by Mycoplasma Contamination of Cell Cultures

1990 • 31 citations

The Productive Infection of Alveolar Macrophages by Simian Immunodeficiency Virus

1989 • 31 citations

Experimental infection of African green monkeys and cynomolgus monkeys with a SIVAGM strain isolated from a healthy African green monkey.

1990 • 31 citations

Hematologic abnormalities in simian acquired immune deficiency syndrome.

1986 • 31 citations

Transmission of the Simian Immunodeficiency Virus SIV_mne in Macaques and Baboons

1989 • 31 citations

Functional analysis of long terminal repeats derived from four strains of simian immunodeficiency virus SIVAGM in Relation to Other Primate Lentiviruses

1991 • 30 citations

An immunopathologic evaluation of lymph nodes from monkey and man with acquired immune deficiency syndrome and related conditions

1985 • 30 citations

Complementation of the rev gene mutation among human and simian lentiviruses

1990 • 30 citations

Cytotoxic T-cell response to simian immunodeficiency virus by cynomolgus macaque monkeys immunized with recombinant vaccinia virus

1991 • 30 citations

Association of Interleukin-6 in the Pathogenesis of Acutely Fatal SIV_smm/PBj-14in Pigtailed Macaques*

1993 • 30 citations

Mutational analysis of the simian immunodeficiency virus SIVmac nef gene

1991 • 29 citations

Simian immunodeficiency virus infection of macaque bone marrow macrophages correlates with disease progression in vivo.

1991 • 29 citations

Immunization of simian immunodeficiency virus-infected rhesus monkeys with soluble human CD4 elicits an antiviral response.

1991 • 29 citations

In Vitro and in Vivo Infection of Rhesus Monkey Microglial Cells by Simian Immunodeficiency Virus

1993 • 29 citations

Infection of Macaque Monkeys With Simian Immunodeficiency Virus From African Green Monkeys: Virulence and Activation of Latent Infection

1989 • 28 citations

Molecular comparison of retroviruses associated with human and simian AIDS

1985 • 28 citations

HIV-Specific Vaccine Therapy: Concepts, Status, and Future Directions

1992 • 28 citations

Vaginal immunization of rats with a synthetic peptide from human immunodeficiency virus envelope glycoprotein

1992 • 28 citations

Detection of simian immunodeficiency virus DNA in macrophages from infected rhesus macaques

1992 • 28 citations

Protection of vaccinia‐primed macaques against SIV _mne infection by combination immunization with recombinant vaccinia virus and SIV _mne gp160

1993 • 28 citations

Prevention of HIV-2 and SIV Infections in Cynomolgus Macaques by Prophylactic Treatment with 3′-Fluorothymidine

1992 • 28 citations

Anti-cellular Antibodies in Sera from Vaccinated Macaques Can Induce Complement-Mediated Virolysis of Human Immunodeficiency Virus and Simian Immunodeficiency Virus

1993 • 28 citations

Protein of macaques against infection with simian type D retrovirus (SRV-1) by immunization with recombinant vaccinia virus expressing the envelope glycoproteins of either SRV-1 or Mason-Pfizer monkey virus (SRV-3)

1992 • 28 citations

Predominant use of a T-cell receptor V beta gene family in simian immunodeficiency virus Gag-specific cytotoxic T lymphocytes in a rhesus monkey

1992 • 28 citations

Immune defects in simian acquired immunodeficiency syndrome

1985 • 28 citations

Retrovirus Infections of Nonhuman Primates: A Review

1988 • 28 citations

Sequence Variation in the env Gene of Simian Immunodeficiency Virus Recovered from Immunized Macaques is Predominantly in the V1 Region

1993 • 28 citations

Adult T-cell leukemia-like disease in monkey naturally infected with simian retrovirus related to human T-cell leukemia virus type I.

1985 • 27 citations

Malignant Lymphoma in a Colony of Macaca arctoides

1985 • 27 citations

Inactivated Whole SIV Vaccine in Macaques: Evaluation of Protective Efficacy Against Challenge with Cell-Free Virus or Infected Cells

1992 • 27 citations

SIV, STLV-I, and Type D Retrovirus Antibodies in Captive Rhesus Macaques and Immunoblot Reactivity to SIV p27 in Human and Rhesus Monkey Sera

1990 • 27 citations

Antigenic Variation of Molecularly Cloned SIVmac239 during Persistent Infection in a Rhesus Macaque

1993 • 27 citations

Pneumocystis carinii pneumonia in simian immunodeficiency virus infection: Immunohistological and scanning and transmission electron microscopical studies

1991 • 27 citations

A Caution on the Use of SIV/HIVgagAntigen Detection Systems in Neutralization Assays

1992 • 27 citations

Genetic Variation of Simian Immunodeficiency Viruses in Nonhuman Primates

1992 • 27 citations

Nef Proteins of the Human Immunodeficiency Viruses (HIV-1 and HIV-2) and Simian Immunodeficiency Virus (SIV) Are Structurally Similar to Leucine Zipper Transcriptional Activation Factors

1991 • 27 citations

Effect of dosing frequency on ZDV prophylaxis in macaques infected with simian immunodeficiency virus.

1993 • 26 citations

Staphylococcal exotoxin superantigens induce human immunodeficiency virus type 1 expression in naturally infected CD4+ T cells

1992 • 26 citations

The NF-kappa B binding site is necessary for efficient replication of simian immunodeficiency virus of macaques in primary macrophages but not in T cells in vitro

1993 • 26 citations

Simian Immunodeficiency Virus (SIV_sm) Infection of Cynomolgus Monkeys: Effects on Follicular Dendritic Cells in Lymphoid Tissue

1992 • 26 citations

Soluble human CD4 elicits an antibody response in rhesus monkeys that inhibits simian immunodeficiency virus replication.

1991 • 26 citations

Neonatal Disease Induced by SIV Infection of the Rhesus Monkey (Macaca mulatta)

1993 • 26 citations

Viral persistence of simian type D retrovirus (SRV‐2/W) in naturally infected pigtailed macaques (Macaca nemestrina)

1993 • 26 citations

Identification of simian immunodeficiency virus SIVMAC env gene products

1989 • 26 citations

Vaccine Protection Against SIVmac Infection by High- But Not Low-Dose Whole Inactivated Virus Immunogen

1992 • 26 citations

Variation in T‐lymphocyte activation and susceptibility to SIV_PBj‐14‐induced acute death in macaques

1991 • 26 citations

Simian immunodeficiency virus (SIVmac) exhibits complex splicing for tat, rev, and env mRNA

1991 • 25 citations

Passive immunization of macaques against SIV infection

1994 • 25 citations

A non-radioisotopic reverse transcriptase assay using biotin-11-deoxyuridinetriphosphate on primer-immobilized microtiter plates

1992 • 25 citations

Expression of natural antibodies against endogenous and horizontally transmitted macaque retroviruses in captive primates

1981 • 25 citations

Effects of U-75875, a peptidomimetic inhibitor of retroviral proteases, on simian immunodeficiency virus infection in rhesus monkeys

1994 • 25 citations

Neutralization and enhancement of in vitro and in vivo HIV and simian immunodeficiency virus infections

1990 • 25 citations

The Impact of HIV-1 Infection on Phenotypic and Functional Parameters of Cellular Immunity in Chimpanzees

1993 • 25 citations

Characterization of multiple mRNA species of simian immunodeficiency virus from macaques in a CD4+ lymphoid cell line

1991 • 24 citations

Cerebrospinal fluid and serum neopterin and biopterin in D-retrovirus-infected rhesus macaques (Macaca mulatta)

1991 • 24 citations

Monocyte/macrophage giant cell disease in SIV-infected cynomolgus monkeys

1991 • 24 citations

Three epitopic peptides of the simian immunodeficiency virus Nef protein recognized by macaque cytolytic T lymphocytes

1992 • 24 citations

Experimental Infection of African Green Monkeys and Cynomolgus Monkeys With a SIV_AGM Strain Isolated From a Healthy African Green Monkey

1990 • 24 citations

Identification of Broadly Reactive Continuous Antigenic Determinants of Simian Immunodeficiency Virus Glycoproteins

1992 • 24 citations

Trickle Perfusion for Organ Preservation

1972 • 24 citations

Detection of occult simian immunodeficiency virus SIVsmm infection in asymptomatic seronegative nonhuman primates and evidence for variation in SIV gag sequence between in vivo- and in vitro-propagated virus

1991 • 23 citations

Characterization of Monoclonal Antibodies that Distinguish Simian Immunodeficiency Virus Isolates from each Other and from Human Immunodeficiency Virus Types 1 and 2

1990 • 23 citations

Strong Association of Simian Immunodeficiency Virus (SIVagm) Envelope Glycoprotein Heterodimers: Possible Role in Receptor-Mediated Activation

1992 • 23 citations

A solid phase reverse transcriptase micro-assay for the detection of human immunodeficiency virus and other retroviruses in cell culture supernatants

1990 • 23 citations

Use of Infectious Molecular Clones of Simian Immunodeficiency Virus for Pathogenesis Studies

1989 • 23 citations

Lack of immune suppression in SIV-infected natural hosts.

1993 • 23 citations

A formalin inactivated whole SIV_mac vaccine in Ribi adjuvant protects against homologous and heterologous SIV challenge

1992 • 23 citations

Comparison of Protection Afforded by Whole Virus ISCOM Versus MDP Adjuvanted Formalin-Inactivated SIV Vaccines from IV Cell-Free or Cell-Associated Homologous Challenge

1992 • 23 citations

Major core proteins, p24s, of human, simian, and feline immunodeficiency viruses are partly expressed on the surface of the virus-infected cells

1992 • 23 citations

In Vitro Assays for Detecting Neutralizing and Fusion-Inhibiting Antibodies to SIV_MAC251

1991 • 22 citations

Acute lymphoid changes and ongoing immune activation in SIV infection.

1992 • 22 citations

Long‐term protection of macaques against high‐dose type D retrovirus challenge after immunization with recombinant vaccinia virus expressing envelope glycoproteins

1993 • 22 citations

Analytical method for the quantification of 2',3'-didehydro-3'-deoxythymidine, a new anti-human immunodeficiency virus (HIV) agent, by high-performance liquid chromatography (HPLC) and ultraviolet (UV) detection in rat and monkey plasma.

1989 • 21 citations

Macaque CD4⁺T-Cell Subsets: Influence of Activation on Infection by Simian Immunodeficiency Viruses (SIV)

1992 • 21 citations

Simian immunodeficiency virus negative factor suppresses the level of viral mRNA in COS cells

1991 • 21 citations

SIVsmm infection of macaque and mangabey monkeys: correlation between in vivo and in vitro properties of different isolates.

1990 • 21 citations

The production and purification of PCR-derived recombinant simian immunodeficiency virus p27 gag protein; its use in detecting serological and T-cell responses in macaques

1990 • 21 citations

Pathological changes in the reproductive tract of male Rhesus monkeys associated with age and simian AIDS

1992 • 21 citations

In vitro screening for antiretroviral agents against simian immunodeficiency virus (SIV)

1990 • 20 citations

Are gamma delta T cells important for the elimination of virus-infected cells?

1992 • 20 citations

Liver disease in rhesus monkeys infected with simian immunodeficiency virus.

1991 • 20 citations

Fidelity of reverse transcriptase of the simian immunodeficiency virus from African green monkey

1991 • 20 citations

The combined assessment of cellular apoptosis, mitochondrial function and proliferative response to pokeweed mitogen has prognostic value in SIV infection

1993 • 20 citations

The Chemistry of Site-Directed Serology for HIV Infections

1989 • 19 citations

SIV vaccines, 1991—a year in review

1991 • 19 citations

Mucosal Epithelial Cells and Langerhans Cells are Targets for Infection by the Immunosuppressive Type D Retrovirus Simian AIDS Retrovirus Serotype 1

1989 • 19 citations

Activation of an endogenous retrovirus from Tupaia (tree shrew)

1978 • 19 citations

A quantitative reverse transcriptase-polymerase chain reaction for HIV-l-specific RNA species

1992 • 19 citations

Differential inhibitory effects of TIBO derivatives on different strains of simian immunodeficiency virus

1992 • 19 citations

Chimpanzees immunized with recombinant soluble CD4 develop anti-self CD4 antibody responses with anti-human immunodeficiency virus activity.

1992 • 19 citations

West Indian Green Monkeys: Problems in Historical Biogeography

1987 • 19 citations

Viral genetic determinants in SIV_smmPBj pathogenesis

1994 • 19 citations

Characterization of simian immunodeficiency virus-specific T-cell-mediated cytotoxic response of infected rhesus macaques

1989 • 19 citations

Are γδ T cells important for the elimination of virus‐infected cells?

1992 • 18 citations

Kinetics and inhibition of reverse transcriptase from human and simian immunodeficiency viruses

1988 • 18 citations

Molecular diversity of SIVsmm/PBj and a cognate variant, SIVsmm/PGg.

1991 • 18 citations

Whole inactivated SIV vaccine grown on human cells fails to protect against homologous SIV grown on simian cells

1993 • 18 citations

Natural Killer Cell Activity of Rhesus Macaques Against Retrovirus-Pulsed CD4+ Target Cells

1990 • 18 citations

Inoculation of Macaca fascicularis With Simian Immunodeficiency Virus, SIV_mne Immunologic, Serologic, and Pathologic Changes

1990 • 18 citations

Viral and cellular gene expression in CD4+ human lymphoid cell lines infected by the simian immunodeficiency virus, SIV/Mne

1991 • 18 citations

Comparison of serum antibody reactivities to a conformational and to linear antigenic sites in the external envelope glycoprotein of simian immunodeficiency virus (SIVmac) induced by infection and vaccination

1993 • 18 citations

Detection of SIV antigens by HIV-1 antigen capture immunoassays.

1990 • 18 citations

Simian immunodeficiency virus (SIVmac251) membrane lipid mixing with human CD4+ and CD4- cell lines in vitro does not necessarily result in internalization of the viral core proteins and productive infection

1993 • 17 citations

Conversion of an immunogenic human immunodeficiency virus (HIV) envelope synthetic peptide to a tolerogen in chimpanzees by the fusogenic domain of HIV gp41 envelope protein.

1993 • 17 citations

Influence of the Infectious Dose of Simian Immunodeficiency Virus on the Acute Infection in Cynomolgus Monkeys and on the Effect of Treatment with 3′-Fluorothymidine

1992 • 17 citations

Partial purification and characterization of the reverse transcriptase of the simian immunodeficiency virus TYO-7 isolated from an African green monkey

1990 • 17 citations

Elimination of type D retrovirus infection from group-housed rhesus monkeys using serial testing and removal.

1991 • 17 citations

Comparison of protection from homologous cell‐free vs cell‐associated SIV challenge afforded by inactivated whole SIV vaccines

1992 • 17 citations

Carrier bound templates for single tube reverse transcriptase assays and for combined purification and activity analyses, with special reference to HIV

1991 • 17 citations

Ocular manifestation of simian immunodeficiency syndrome (SAIDS)

1990 • 17 citations

Serologic responses to Mycobacterium leprae-specific phenolic glycolipid-I antigen in sooty mangabey monkeys with experimental leprosy.

1988 • 17 citations

First updated and revised survey of worldwide HIV and SIV vaccine challenge studies in nonhuman primates: Progress in first and second order studies

1993 • 17 citations

Comparison of the transcriptional activity of the long terminal repeats of simian immunodeficiency viruses SIVmac251 and SIVmac239 in T-cell lines and macrophage cell lines

1991 • 17 citations

Interstitial pneumonia in simian immunodeficiency virus infection

1992 • 17 citations

Virus isolation and quinolinic acid in primary and chronic simian immunodeficiency virus infection

1993 • 17 citations

Use of Old World Monkeys for Acquired Immunodeficiency Syndrome Research

1989 • 16 citations

Vaccine Studies With the ³²H Reisolate of SIV_mac251: An Overview

1992 • 16 citations

The thymic epithelial reticulum and interdigitating cells in SIV-induced thymus atrophy and its comparison with other forms of thymus involution

1993 • 16 citations

Intra‐amniotic inoculation of pigtailed macaque (Macaca nemestrina) fetuses with SIV and HIV‐1

1993 • 16 citations

Biology of the mycobacterioses

1968 • 16 citations

The nef gene of simian immunodeficiency virus SIVmac1A11

1992 • 16 citations

Antiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue culture

1993 • 16 citations

Autologous Neutralizing Antibodies to SIVsm in Cynomolgus Monkeys Correlate to Prognosis

1993 • 16 citations

The genetic evolution of the envelope gene of simian immunodeficiency virus in cynomolgus macaques infected with a complex virus pool

1992 • 16 citations

Epidemiologic aspects of an outbreak of acquired immunodeficiency in rhesus monkeys (Macaca mulatta).

1984 • 16 citations

Monocyte function in rhesus monkeys with simian acquired immune deficiency syndrome

1985 • 16 citations

Transmission of SIV_Mne from female to male Macaca nemestrina

1992 • 16 citations

Molecular Characterization of SIV in Tissues from Experimentally Infected Macaques

1990 • 16 citations

Characterization of group specific antibodies in primates: Studies with SIV envelope in macaques

1992 • 15 citations

Effect of simian immunodeficiency virus infection on tumor necrosis factor-alpha production by alveolar macrophages.

1991 • 15 citations

Replication and persistence of simian immunodeficiency virus variants after passage in macaque lymphocytes and established human cell lines

1993 • 15 citations

Molecular Clones from a Non-Acutely Pathogenic Derivative of SIV_smmPBj14: Characterization and Comparison to Acutely Pathogenic Clones

1992 • 15 citations

Identification of B-cell antigenic sites on HIV-2 gp125.

1992 • 15 citations

Rhesus monkey macrophages infected with simian immunodeficiency virus cause rapid lysis of CD4-bearing lymphocytes

1991 • 15 citations

Potential significance of the cellular immune response against the macaque strain of simian immunodeficiency virus (SIVMAC) in immunized and infected rhesus macaques

1992 • 15 citations

Infectivity and pathogenesis of titered dosages of simian immunodeficiency virus experimentally inoculated into longtailed macaques (Macaca fascicularis).

1993 • 15 citations

Activity of CD4-Pseudomonas exotoxin against cells expressing diverse forms of the HIV and SIV envelope glycoproteins.

1992 • 15 citations

Prevention of transmission of simian immunodeficiency virus from vaccinated macaques that developed transient virus infection following challenge

1993 • 15 citations

Alternate pathways of secretion of simian immunodeficiency virus envelope glycoproteins

1993 • 14 citations

Immunodeficiency Disorders and Retroviruses

1988 • 14 citations

International Collaboration Comparing Neutralization and Binding Assays for Monoclonal Antibodies to Simian Immunodeficiency Virus

1993 • 14 citations

Accessory cells and macrophages in the histopathology of SIVsm-infected cynomolgus monkeys

1993 • 14 citations

A History of Poliomyelitis

1972 • 14 citations

Development of a BCG Recombinant Vehicle for Candidate AIDS Vaccines

1990 • 14 citations

Postexposure Immunotherapy of Simian Immunodeficiency Virus (SIV) Infected Rhesus With an SIV Immunogen

1989 • 14 citations

Cytotoxic T lymphocyte epitopes shared between HIV‐1, HIV‐2, and SIV

1993 • 14 citations

Characterization of B-Cell Epitopes in the Envelope Glycoproteins of Simian Immunodeficiency Virus

1993 • 14 citations

Detection of simian immunodeficiency virus RNA from infected rhesus macaques by the polymerase chain reaction

1992 • 14 citations

Genetic Diversity of Simian Immunodeficiency Virus

1989 • 14 citations

Serological and structural comparison of HIV, SIVmac, SIVagm and SIVsm, four primate lentiviruses

1987 • 14 citations

Mutational Analysis of Simian Immunodeficiency Virus From African Green Monkeys and Human Immunodeficiency Virus Type 2

1990 • 14 citations

Genetic Analysis and Infection of SIV_AGM and SIV_MND

1989 • 14 citations

Synthetic peptides of envelope proteins of two different strains of simian aids retrovirus (SRV-1 and SRV-2) represent unique antigenic determinants for serum neutralizing antibodies

1990 • 13 citations

Atresia of the dominant ovarian follicle in rhesus monkeys is detected within 24 hours of estradiol treatment

1989 • 13 citations

Use of probes and amplification techniques for the diagnosis and prognosis of human immunodeficiency virus (HIV-1) infections

1993 • 13 citations

Heterogeneity in the recognition of the simian immunodeficiency virus envelope glycoprotein by CD4+ T cell clones from immunized macaques.

1992 • 13 citations

Immunization with Lentivirus-Like Particles Elicits a Potent SIV-Specific Recall Cytotoxic T-Lymphocyte Response in Rhesus Monkeys

1993 • 13 citations

Multifactorial etiology of anemia in SIV-infected rhesus macaques: decreased BFU-E formation, serologic evidence of autoimmune hemolysis, and an exuberant erythropoietin response.

1993 • 13 citations

Two strains of SIVmac show differential transactivation mediated by sequences in the promoter

1992 • 13 citations

Antibody response to the negative regulatory factor (nef) in experimentally infected macaques: Correlation with viremia, disease progression, and seroconversion to structural viral proteins

1991 • 13 citations

Treatment of Acute SIV infection in cynomolgus Monkeys with 2′,3′-dideoxyinosine (ddl) and 2′,3′-dideoxythymidiene (d4T)

1991 • 13 citations

Clinical and pathologic findings in infant rhesus macaques infected with SIV_smm by maternal transmission

1993 • 13 citations

Molecular cloning of a type D retrovirus from human cells (PMFV) and its homology to simian acquired immunodeficiency type D retroviruses

1989 • 13 citations

Cytokine enhancement of simian immunodeficiency virus (SIV/mac) from a chronically infected cloned T-cell line (HuT-78)

1991 • 12 citations

Simian immunodeficiency virus-specific T-cell-mediated proliferative response of infected rhesus macaques

1990 • 12 citations

Self-Limiting Infection by int/nef-Double Mutants of Simian Immunodeficiency Virus

1993 • 12 citations

B-cell epitope mapping of the entire SIVagm envelope glycoprotein including fine mapping of immunogenic regions.

1992 • 12 citations

SIV of stump‐tailed macaque (SIV_stm) is a divergent Asian isolate

1991 • 12 citations

Interleukin-6 and retroperitoneal fibromatosis from SRV-2-infected macaques with simian AIDS.

1991 • 12 citations

Stimulation of Specific Immune Responses to Simian Immunodeficiency Virus Using Chimeric Hepatitis B Core Antigen Particles

1992 • 12 citations

Multifactorial etiology of anemia in SIV‐infected rhesus macaques: Decreased BFU‐E formation, serologic evidence of autoimmune hemolysis, and an exuberant erythropoietin response

1993 • 12 citations

Severe autoimmune hemolytic anemia in SIV_smm9‐infected Macaca mulatta

1991 • 12 citations

Progress in the development of simian immunodeficiency virus vaccines

1990 • 12 citations

Requirements for simian immunodeficiency virus antigen-specific in vitro proliferation of T cells from infected rhesus macaques and sooty mangabeys

1990 • 12 citations

Use of simian immunodeficiency virus for evaluation of AIDS vaccine strategies

1989 • 12 citations

Detection of Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2 Capsid Antigens by a Monoclonal Antibody-Based Antigen Capture Assay

1993 • 12 citations

Immunochemistry of the dominating antigenic region Ala582 to Cys604 in the transmembranous protein of simian and human immunodeficiency virus.

1989 • 11 citations

Immunization of Macaca fascicularis with inactivated SIV preparations: Challenge with human‐ or monkey‐derived SIV and the effects of a longer immunization schedule

1993 • 11 citations

The assessment of nucleotide sequence diversity by the polymerase chain reaction is highly reproducible

1992 • 11 citations

Characterization of T‐ and B‐cell epitopes of a simian retrovirus (SRV‐2) envelope protein

1991 • 11 citations

Worldwide survey of AIDS vaccine challenge studies in nonhuman primates: Vaccines associated with active and passive immune protection from live virus challenge

1992 • 11 citations

Molecular diversity of SIV_smm/PBj and a cognate variant, SIV_smm/PGg

1991 • 11 citations

A Formalin-Fixed Whole SIV Vaccine Induces Protective Responses that are Cross-Protective and Durable

1992 • 11 citations

Cellular immune response to SIVmac and HIV-2 in macaques: model for the human HIV-1 infection.

1993 • 11 citations

Genetic characterization of simian immunodeficiency virus isolated from an African mandrill

1992 • 10 citations

Soluble and membrane-associated interleukin 2 receptor-alpha expression in rhesus monkeys infected with simian immunodeficiency virus.

1990 • 10 citations

Genetic variation of the SIVagm transmembrane glycoprotein in naturally and experimentally infected primates

1993 • 10 citations

Tumour necrosis factor and interleukin 6 production during interaction between activated CD4+ lymphocytes and simian immunodeficiency virus-infected macrophages

1992 • 10 citations

Antibody Recognition of SIVmac Envelope Peptides in Plasma from Macaques Experimentally Infected with SIV/Mne

1989 • 10 citations

N-Linked Oligosaccharides of Simian Immunodeficiency Virus Envelope Glycoproteins Are Dispensable for the Interaction with the CD4 Receptor

1993 • 10 citations

Isolation and Characterization of the Neutralizable Epitope of Simian Retrovirus-1 (SRV-1) and of the Cell Receptor for the Virus

1991 • 10 citations

The importance of nonhuman primate research in the battle against AIDS: a historical perspective.

1993 • 9 citations

Early appearance of simian immunodeficiency virus (SIV) antigen and antibodies as variables in evaluating antiviral drugs in macaques

1992 • 9 citations

Functional classification of simian immunodeficiency virus isolated from a chimpanzee by transactivators

1992 • 9 citations

SIV envelope glycoprotein epitopes recognized by antibodies from infected or vaccinated rhesus macaques

1993 • 9 citations

HIV with Multiple Gene Deletions as a Live Attenuated Vaccine for AIDS

1992 • 9 citations

Coexpression of biologically active simian immunodeficiency virus (SIV) rev and env in an SV40 system: The SIV rev gene regulates Env expression

1990 • 9 citations

Antibody‐dependent enhancement and neutralization pattern of sera from SIV‐infected or HIV‐2‐vaccinated rhesus monkeys

1991 • 9 citations

Arthritis in rhesus monkeys experimentally infected with simian immunodeficiency virus (SIV/DELTA).

1991 • 9 citations

Characterization of Rhesus Macaque B-Lymphoblastoid Cell Lines Infected with Simian Type D Retrovirus

1991 • 9 citations

Site-Directed ELISA Identifies a Highly Antigenic Region of the Simian Immunodeficiency Virus Transmembrane Glycoprotein

1988 • 9 citations

Cellular Immune Response of SIV‐Infected Rhesus Macaques

1990 • 9 citations

Interleukin‐6 and retroperitoneal fibromatosis from SRV‐2–infected macaques with simian AIDS

1991 • 9 citations

Simian Immunodeficiency Virus (mac 251-32H) Transmembrane Protein Sequence Remains Conserved Throughout the Course of Infection in Macaques

1993 • 8 citations

Transmission of Retroviral Infection by Transfusion of Seronegative Blood in Nonhuman Primates

1991 • 8 citations

Antibodies to type D retrovirus in talapoin monkeys

1991 • 8 citations

Dynamics of the immune system response in cerebrospinal fluid and blood of SIV_mac‐infected rhesus monkeys

1993 • 8 citations

A formalin inactivated whole SIV vaccine and a glycoprotein-enriched subunit vaccine confers protection against experimental challenge with pathogenic live SIV in rhesus monkeys.

1990 • 8 citations

The Simian Immunodeficiency Virus (SIV) rev Gene Regulates Env Expression

1990 • 8 citations

Sequences responsible for efficient replication of simian immunodeficiency virus SIVMND in cells of the monocyte/macrophage lineage

1992 • 8 citations

Detection of serum antibodies in Ethiopian baboons that cross‐react with SIV, HTLV‐I, and type D retroviral antigens

1993 • 8 citations

Detection of Simian Immunodeficiency Virus in Macaque Lymph Nodes With a SIV_mac Envelope Probe

1989 • 8 citations

Generation of deletion mutants of simian immunodeficiency virus incapable of proviral integration

1993 • 8 citations

Structural analysis of p19 and p24 core polypeptides of primate lymphotropic retroviruses (PLRV)

1986 • 8 citations

Propagation of SIV Vectors by Genetic Complementation with a HeterologousenvGene

1992 • 8 citations

Substrate Specificity of the Human (Type 1) and Simian Immunodeficiency Virus Proteases

1991 • 8 citations

The importance of nonhuman primate research in the battle against AIDS: A historical perspective

1993 • 8 citations

Identification of a Gag Protein Epitope Conserved Among All Four Groups of Primate Immunodeficiency Viruses by Using Monoclonal Antibodies

1992 • 8 citations

Neutralization epitope in the envelope glycoprotein of simian retrovirus‐1 (SRV‐1) and identification of the virus receptor

1991 • 8 citations

Quantitation of infectious human immunodeficiency virus using a modified plaque forming assay

1988 • 7 citations

VACCINATION AGAINST VIRALLY INDUCED ANIMAL TUMORS11Supported by grants AI20573 from NIAID, CA37467 from NCI, contract N01-C0-23910 P.R.I., and the State of California Universitywide Task Force on AIDS.

1985 • 7 citations

Historical and contemporary perspectives in vaccine developments: from the vantage of cancer.

1992 • 7 citations

Early hematologic changes in rhesus macaques (Macaca mulatta) infected with pathogenic and nonpathogenic isolates of SIVmac

1993 • 7 citations

CD4-Binding of gp130 Micelles Isolated from SIV^agmTYO-7

1992 • 7 citations

Neutralizing antibodies modulate replication of simian immunodeficiency virus SIVmac in primary macaque macrophages

1992 • 7 citations

SIV and FIV Vaccine Studies at UC Davis: 1991 Update

1992 • 7 citations

Functional analysis of biologically distinct genetic variants of simian immunodeficiency virus isolated from a mandrill

1992 • 7 citations

Sequence Variability of Simian Immunodeficiency Virus in a Persistently Infected Rhesus Monkey

1990 • 7 citations

Infection of rhesus monkeys with topical instillation of simian immunodeficiency virus (SIV)_B670 into the conjunctival sac

1991 • 7 citations

Immunobiological properties of a recombinant simian retro virus-1 envelope protein and a neutralizing monoclonal antibody directed against it

1991 • 6 citations

Identification of four antibody-binding sites in the envelope proteins of simian immunodeficiency virus, SIVsm

1993 • 6 citations

HLA-DR expression in macaque neuroendothelial cells in vitro and during SIV encephalitis

1991 • 6 citations

In VitroSpontaneous Production of Anti-SIV Antibodies Is a Reliable Tool in the Follow-Up of Protection of SIV-Vaccinated Monkeys

1993 • 6 citations

Comparative studies ontat mutants of three primate lentiviruses

1990 • 6 citations

Simian immunodeficiency virus (SIVsm) isolation from blood and brain of experimentally infected macaques

1991 • 6 citations

Oral Priming Followed by Parenteral Immunization with HIV-Immunosomes Induce HIV-1-Specific Salivary and Circulatory IgA in Mice and Rabbits

1992 • 5 citations

Molecular Interactions between Human Immunodeficiency Virus Type 1 and Human Cytomegalovirus^a

1990 • 5 citations

The induction of neutralizing antibodies by synthetic peptides of the envelope protein of type D simian retrovirus-1 (SRV-1)

1991 • 5 citations

Expression of enzymatically active reverse transcriptase of simian immunodeficiency virus in bacteria: Sensitivity to nucleotide analogue inhibitors

1990 • 5 citations

Study of long-term cultures of simian immunodeficiency virus (SIVmac 251)-infected peripheral blood lymphocytes.

1990 • 4 citations

The simian immunodeficiency viruses

1991 • 4 citations

Analysis of HIV-1 expression in vivo with in situ hybridization and the polymerase chain reaction

1992 • 4 citations

Antigen capture assay for detection of simian type D retroviruses in cell cultures and plasma samples.

1989 • 4 citations

Effects of SIV infection on fetal development and pregnancy outcome in the rhesus macaque (Macaca mulatta)

1993 • 4 citations

Cloning and expression of the complete SIVagm pol region in E. coli. Purification and partial characterization of the reverse transcriptase.

1990 • 4 citations

Generation of deletion mutants of simian immunodeficiency virus incapable of proviral integration

1992 • 4 citations

A simple, rapid immunoassay for the detection of simian immunodeficiency virus antibodies.

1991 • 3 citations

Functional analysis of HIV1 and SIV Nef proteins

1992 • 3 citations

Serological survey for two simian retroviruses in macaques and African green monkeys.

1990 • 3 citations

Transcomplementation of simian immunodeficiency virus Rev with human T-cell leukemia virus type I Rex

1993 • 2 citations

Recovery of the simian immunodeficiency virus (SIV) and depression of colony formation in in vitro infected progenitor cell‐enriched rhesus bone marrow (BM)

1991 • 2 citations

Type D SRV‐2 virus‐specific CD8⁺ and CD4^‐ CD8^‐ T cells that regulate virus‐induced T cell proliferation in Celebes macaques

1993 • 1 citations

73 Lack of involvement of transactivating herpesviruses in acute SIV infection in monkeys

1993 • 1 citations

Lack of permissivity of human monoclonal CD4+ lymphocytes to HIV.

1990 • 1 citations

PCR amplification of large genomic fragments from human and simian immunodeficiency virus infected cell lines

1992 • 1 citations