Association of Interleukin-6 in the Pathogenesis of Acutely Fatal SIV_smm/PBj-14in Pigtailed Macaques*

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

1990 • 1,377 citations

Production of hybridoma growth factor by human monocytes

1987 • 1,133 citations

HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor

1988 • 607 citations

Infection with HIV is associated with elevated IL-6 levels and production.

1990 • 594 citations

Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms.

1990 • 529 citations

Purification and physico-chemical characterization of rabbit tumor necrosis factor.

1980 • 386 citations

Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor

1989 • 331 citations

Regulation of BSF-2/IL-6 production by human mononuclear cells. Macrophage-dependent synthesis of BSF-2/IL-6 by T cells.

1988 • 286 citations

Monocyte-Derived Human B-Cell Growth Factor Identified as Interferon-β ₂ (BSF-2, IL-6)

1988 • 281 citations

Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes.

1989 • 230 citations

Sequence analysis and acute pathogenicity of molecularly cloned SIVSMM-PBj14

1990 • 218 citations

Identification and Biologic Characterization of an Acutely Lethal Variant of Simian Immunodeficiency Virus from Sooty Mangabeys (SIV/SMM)

1989 • 211 citations

Isolation of a lentivirus from a macaque with lymphoma: comparison with HTLV-III/LAV and other lentiviruses

1986 • 208 citations

Nucleotide sequence and genome organization of biologically active proviruses of the bovine immunodeficiency-like virus

1990 • 196 citations

Induction of interleukin-6 during human immunodeficiency virus infection

1990 • 191 citations

Cloning of HTLV-4 and its relation to simian and human immunodeficiency viruses

1987 • 167 citations

Disease specificity of nondefective Friend and Moloney murine leukemia viruses is controlled by a small number of nucleotides

1987 • 164 citations

Interleukin-6 gene expression in human endothelial cells: RNA start sites, multiple IL-6 proteins and inhibition of proliferation

1989 • 131 citations

Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant

1993 • 92 citations

Simian Immunodeficiency Virus Infection of Macaques: End-Stage Disease Is Characterized by Widespread Distribution of Proviral DNA in Tissues

1991 • 86 citations

Influence of enhancer sequences on thymotropism and leukemogenicity of mink cell focus-forming viruses

1989 • 76 citations

Structural diversity and nuclear protein binding sites in the long terminal repeats of feline leukemia virus

1990 • 62 citations

Infection of Rhesus and Cynomolgus Macaques with a Rapidly Fatal SIV (SIV_SMM/PBj) Isolate From Sooty Mangabeys

1992 • 61 citations

SIV Infection of Macaques as a Model for AIDS Pathogenesis

1992 • 52 citations

Early Pathogenesis of Disease Caused by SIVsmmPBjl4 Molecular Clone 1.9 in Macaques

1993 • 40 citations

Sir,

1990 • 37 citations

Comparison of the transcriptional properties of the friend and moloney retrovirus long terminal repeats: Importance of tandem duplications and of the core enhancer sequence

1985 • 28 citations