Mechanisms of Retrovirus Replication

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus

1970 • 2,061 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

DNA TOPOISOMERASES

1985 • 1,524 citations

Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection.

1990 • 1,465 citations

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

1982 • 1,429 citations

Gene Transfer into Humans — Immunotherapy of Patients with Advanced Melanoma, Using Tumor-Infiltrating Lymphocytes Modified by Retroviral Gene Transduction

1990 • 1,307 citations

Conserved Folding in Retroviral Proteases: Crystal Structure of Synthetic HIV-1 Protease

1989 • 1,155 citations

Nucleotide sequence of Moloney murine leukaemia virus

1981 • 1,079 citations

NONVIRAL RETROPOSONS: GENES, PSEUDOGENES, AND TRANSPOSABLE ELEMENTS GENERATED BY THE REVERSE FLOW OF GENETIC INFORMATION

1986 • 1,032 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

The Accuracy of Reverse Transcriptase from HIV-1

1988 • 982 citations

Fidelity of HIV-1 Reverse Transcriptase

1988 • 919 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Nucleotide sequence of rous sarcoma virus

1983 • 901 citations

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

1989 • 883 citations

Evidence That the Leucine Zipper Is a Coiled Coil

1989 • 869 citations

RNA tumor viruses

1982 • 833 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

1987 • 796 citations

Reverse Transcriptase Encoded by a Human Transposable Element

1991 • 748 citations

Molecular Targets for AIDS Therapy

1990 • 736 citations

RNA POLYMERASE II

1991 • 729 citations

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

1983 • 700 citations

Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas

1982 • 624 citations

pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane

1987 • 620 citations

Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

1988 • 608 citations

Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus

1983 • 586 citations

Activators and targets

1990 • 582 citations

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

1984 • 564 citations

Viral and Cellular Membrane Fusion Proteins

1990 • 517 citations

Retroviruses

1988 • 512 citations

Molecular model for the transposition and replication of bacteriophage Mu and other transposable elements.

1979 • 503 citations

Genetic and physical linkage of exogenous sequences in transformed cells

1980 • 486 citations

Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus

1983 • 464 citations

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

1990 • 440 citations

Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter

1991 • 439 citations

Poly(A) signals

1991 • 438 citations

A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor

1988 • 427 citations

RNA-Directed DNA Synthesis and RNA Tumor Viruses

1972 • 420 citations

The CD4 antigen: Physiological ligand and HIV receptor

1988 • 413 citations

Mapping unintegrated avian sarcoma virus DNA: Termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA

1978 • 391 citations

Retrovirus Packaging Cells

1990 • 388 citations

A VIRUS IN CHICK EMBRYOS WHICH INDUCES RESISTANCE IN VITRO TO INFECTION WITH ROUS SARCOMA VIRUS

1960 • 380 citations

RNA Polymerase B (II) And General Transcription Factors

1990 • 355 citations

Analysis of avian leukosis virus DNA and RNA in bursal tumors: Viral gene expression is not required for maintenance of the tumor state

1981 • 346 citations

Crystal structure of a retroviral protease proves relationship to aspartic protease family

1989 • 345 citations

Murine leukemia virus protease is encoded by the gag-pol gene and is synthesized through suppression of an amber termination codon.

1985 • 334 citations

Evaluation of Natural Products as Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase

1991 • 332 citations

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity.

1990 • 329 citations

Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome.

1988 • 316 citations

Generation of avian myeloblastosis virus structural proteins by proteolytic cleavage of a precursor polypeptide

1975 • 308 citations

Binding of a reduced peptide inhibitor to the aspartic proteinase from Rhizopus chinensis: implications for a mechanism of action.

1987 • 305 citations

How RNA polymerase II terminates transcription in higher eukaryotes

1989 • 301 citations

Myristylation site in Pr65gag is essential for virus particle formation by Moloney murine leukemia virus.

1986 • 300 citations

Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism.

1988 • 299 citations

Complete Nucleotide Sequence of the Drosophila Transposable Element Copia: Homology Between Copia and Retroviral Proteins

1985 • 299 citations

Human immunodeficiency virus long terminal repeat responds to T-cell activation signals.

1987 • 292 citations

Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations.

1990 • 282 citations

Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: implications for retrovirus integration.

1980 • 280 citations

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

1992 • 276 citations

X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor.

1990 • 274 citations

Acylation of Proteins with Myristic Acid Occurs Cotranslationally

1987 • 274 citations

Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus.

1990 • 264 citations

Highly preferred targets for retrovirus integration

1988 • 262 citations

Structure of the termini of DNA intermediates in the integration of retroviral DNA: Dependence on IN function and terminal DNA sequence

1989 • 260 citations

Six distinct nuclear factors interact with the 75-base-pair repeat of the Moloney murine leukemia virus enhancer.

1987 • 259 citations

Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol

1987 • 258 citations

Small finger protein of avian and murine retroviruses has nucleic acid annealing activity and positions the replication primer tRNA onto genomic RNA.

1988 • 255 citations

Fatty Acylation of Proteins

1988 • 253 citations

Retroviruses as mutagens: Insertion and excision of a nontransforming provirus alter expression of a resident transforming provirus

1981 • 253 citations

Characterization of Moloney murine leukemia virus mutants with single-amino-acid substitutions in the Cys-His box of the nucleocapsid protein

1989 • 252 citations

Receptor interference groups of 20 retroviruses plating on human cells

1990 • 249 citations

Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites

1987 • 248 citations

Nucleosome Positioning: Occurrence, Mechanisms, and Functional Consequences

1991 • 248 citations

Genetic recombinants and heterozygotes derived from endogenous and exogenous avian RNA tumor viruses

1973 • 245 citations

Construction and analysis of deletion mutations in the pol gene of moloney murine leukemia virus: A new viral function required for productive infection

1984 • 244 citations

Myristylation is required for intracellular transport but not for assembly of D-type retrovirus capsids

1987 • 241 citations

Nuclear import-export: In search of signals and mechanisms

1991 • 233 citations

The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons

1991 • 230 citations

Association of Viral Reverse Transcriptase with an Enzyme degrading the RNA Moiety of RNA-DNA Hybrids

1971 • 226 citations

Ordered Interstrand and Intrastrand DNA Transfer During Reverse Transcription

1988 • 222 citations

Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA

1977 • 220 citations

RNA pseudoknots: Translational frameshifting and readthrough on viral RNAs

1990 • 219 citations

Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions.

1990 • 214 citations

Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin

1986 • 212 citations

Virus infection of murine teratocarcinoma stem cell lines

1977 • 212 citations

Amphotropic host range of naturally occuring wild mouse leukemia viruses

1976 • 210 citations

The pH independence of mammalian retrovirus infection

1990 • 210 citations

Transcriptionally active genome regions are preferred targets for retrovirus integration

1990 • 210 citations

A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT.

1983 • 208 citations

Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities.

1988 • 206 citations

Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers.

1992 • 194 citations

The reverse transcriptase

1977 • 194 citations

Molecular Biology of RNA Tumor Viruses

1980 • 194 citations

Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo.

1986 • 194 citations

The terminal nucleotides of retrovirus DNA are required for integration but not virus production

1983 • 193 citations

Complete nucleotide sequence of the Drosophila transposable element copia: homology between copia and retroviral proteins.

1985 • 190 citations

Encapsidation sequences for spleen necrosis virus, an avian retrovirus, are between the 5' long terminal repeat and the start of the gag gene.

1982 • 190 citations

Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro.

1989 • 189 citations

Nucleotide Sequence of SRV-1, a Type D Simian Acquired Immune Deficiency Syndrome Retrovirus

1986 • 188 citations

Analysis of the primary structure of the long terminal repeat and the gag and pol genes of the human spumaretrovirus

1988 • 188 citations

Rous sarcoma virus nucleic acid-binding protein p12 is necessary for viral 70S RNA dimer formation and packaging

1986 • 187 citations

In vivo modification of retroviral gag gene-encoded polyproteins by myristic acid

1983 • 186 citations

Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells.

1991 • 181 citations

A retrovirus-like strategy for expression of a fusion protein encoded by yeast transposon Ty1

1985 • 180 citations

The DNA Provirus Hypothesis

1976 • 180 citations

Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease.

1989 • 180 citations

Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificity.

1990 • 178 citations

Properties of avian retrovirus particles defective in viral protease

1990 • 172 citations

Tales of poly(A): a review

1990 • 171 citations

Site on the RNA of an avian sarcoma virus at which primer is bound

1975 • 170 citations

Interaction of the TGGCA-binding protein with upstream sequences is required for efficient transcription of mouse mammary tumor virus.

1987 • 168 citations

Purification and characterization of murine retroviral reverse transcriptase expressed in Escherichia coli.

1985 • 167 citations

Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism

1991 • 166 citations

Reverse transcription in the eukaryotic genome: retroviruses, pararetroviruses, retrotransposons, and retrotranscripts.

1985 • 166 citations

Retroviral integration into minichromosomes in vitro.

1992 • 166 citations

Varying the position of a retrovirus packaging sequence results in the encapsidation of both unspliced and spliced RNAs

1985 • 165 citations

Evidence that a downstream pseudoknot is required for translational read-through of the Moloney murine leukemia virus gag stop codon.

1991 • 165 citations

Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties.

1985 • 164 citations

The retrovirus pol gene encodes a product required for DNA integration: identification of a retrovirus int locus.

1984 • 164 citations

Human immunodeficiency virus infection of T cells and monocytes proceeds via receptor-mediated endocytosis.

1988 • 163 citations

Replication-competent retrovirus vectors for the transfer and expression of gene cassettes in avian cells

1991 • 163 citations

8 Pathogenesis of Retrovirus-induced Disease

1982 • 161 citations

Studies with crosslinking reagents on the oligomeric structure of the env glycoprotein of HIV

1989 • 160 citations

Avian retroviral long terminal repeats bind CCAAT/enhancer-binding protein.

1989 • 160 citations

A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus

1990 • 160 citations

Close structural resemblance between putative polymerase of a Drosophila transposable genetic element 17.6 and pol gene product of Moloney murine leukaemia virus.

1985 • 159 citations

Adaptation of a retrovirus as a eucaryotic vector transmitting the herpes simplex virus thymidine kinase gene.

1982 • 157 citations

INTEGRATION SPECIFICITY OF RETROTRANSPOSONS AND RETROVIRUSES

1990 • 155 citations

Feline leukemia virus subgroup B uses the same cell surface receptor as gibbon ape leukemia virus

1992 • 155 citations

HIV-1 RT-associated ribonuclease H displays both endonuclease and 3′----5′ exonuclease activity.

1990 • 154 citations

Enhancer sequences and the regulation of gene transcription

1988 • 153 citations

Creation and expression of myristylated forms of Rous sarcoma virus gag protein in mammalian cells

1989 • 152 citations

CUG initiation codon used for the synthesis of a cell surface antigen coded by the murine leukemia virus

1989 • 152 citations

Interference grouping of murine leukemia viruses: A distinct receptor for the MCF-Recombinant viruses in mouse cells

1982 • 151 citations

Retroviral Proteinases

1990 • 145 citations

Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid

1991 • 144 citations

Circles with two tandem LTRs are precursors to integrated retrovirus DNA

1984 • 138 citations

The human immunodeficiency virus type 1 polyadenylylation signal: a 3' long terminal repeat element upstream of the AAUAAA necessary for efficient polyadenylylation.

1991 • 136 citations

Pseudotypes of Vesicular Stomatitis Virus with the Coat of Murine Leukaemia and of Avian Myeloblastosis Viruses

1972 • 136 citations

Mutations in Rous sarcoma virus nucleocapsid protein p12 (NC): deletions of Cys-His boxes

1988 • 136 citations

Tissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequences

1985 • 130 citations

Retroviral proteases: First glimpses at the anatomy of a processing machine

1989 • 128 citations

Progress toward human gene therapy

1990 • 127 citations

Protein fatty acid acylation: enzymatic synthesis of an N-myristoylglycyl peptide.

1986 • 123 citations

Patterns of proviral insertion and deletion in avian leukosis virus-induced lymphomas

1986 • 122 citations

Intramolecular integration within Moloney murine leukemia virus DNA

1981 • 122 citations

Mechanism of translation of monocistronic and multicistronic human immunodeficiency virus type 1 mRNAs.

1992 • 121 citations

Fatty acylation of cellular proteins. Temporal and subcellular differences between palmitate and myristate acylation.

1986 • 120 citations

Sequence relationships of type D retroviruses which cause simian acquired immunodeficiency syndrome

1987 • 117 citations

Homologous and nonhomologous recombination in monkey cells.

1983 • 114 citations

Retroviral integration sites in transgenic Mov mice frequently map in the vicinity of transcribed DNA regions

1990 • 113 citations

Mutants of the Rous sarcoma virus envelope glycoprotein that lack the transmembrane anchor and cytoplasmic domains: analysis of intracellular transport and assembly into virions

1987 • 113 citations

cis-Acting RNA packaging locus in the 115-nucleotide direct repeat of Rous sarcoma virus

1983 • 112 citations

Mutations of the Rous sarcoma virus env gene that affect the transport and subcellular location of the glycoprotein products.

1984 • 109 citations

An analysis of the role of tRNA species as primers for the transcription into DNA of RNA tumor virus genomes

1977 • 109 citations

Progress toward human gene therapy

1990 • 109 citations

Differential protein binding in lymphocytes to a sequence in the enhancer of the mouse retrovirus SL3-3.

1988 • 108 citations

Characterization of large deletions occurring during a single round of retrovirus vector replication: novel deletion mechanism involving errors in strand transfer

1991 • 106 citations

Efficient Incorporation of Human CD4 Protein into Avian Leukosis Virus Particles

1990 • 105 citations

High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme.

1989 • 104 citations

Comparison of the crystal structures and intersubunit interactions of human immunodeficiency and Rous sarcoma virus proteases.

1990 • 104 citations

Murine leukemia virus morphogenesis: cleavage of P70 in vitro can be accompanied by a shift from a concentrically coiled internal strand ("immature") to a collapsed ("mature") form of the virus core.

1977 • 102 citations

Tunicamycin treatment of CHO cells abrogates multiple blocks to retrovirus infection, one of which is due to a secreted inhibitor

1992 • 102 citations

Unmyristylated Moloney murine leukemia virus Pr65gag is excluded from virus assembly and maturation events

1989 • 102 citations

Retroid Virus Genome Replication

1987 • 100 citations

Point mutations in the Moloney murine leukemia virus enhancer identify a lymphoid-specific viral core motif and 1,3-phorbol myristate acetate-inducible element

1990 • 99 citations

Structure of viral DNA and RNA in mammalian cells infected with avian sarcoma virus

1980 • 99 citations

Mechanism of suppression of the long terminal repeat of Moloney leukemia virus in mouse embryonal carcinoma cells.

1989 • 99 citations

Initiation of translation at CUG, GUG, and ACG codons in mammalian cells

1990 • 98 citations

Effect of dimerization on the conformation of the encapsidation Psi domain of Moloney murine leukemia virus RNA

1992 • 97 citations

Promoter interactions in retrovirus vectors introduced into fibroblasts and embryonic stem cells

1991 • 95 citations

Involvement of retrovirus reverse transcriptase-associated RNase H in the initiation of strong-stop (+) DNA synthesis and the generation of the long terminal repeat

1984 • 95 citations

Reverse transcriptase as the major determinant for selective packaging of tRNA's into Avian sarcoma virus particles

1980 • 95 citations

Synthesis and circularization of N- and B-tropic retroviral DNA Fv-1 permissive and restrictive mouse cells.

1980 • 95 citations

Deletion mutants of Moloney murine leukemia virus which lack glycosylated gag protein are replication competent

1983 • 95 citations

Correlation of leukemogenic potential of murine retroviruses with transcriptional tissue preference of the viral long terminal repeats

1987 • 93 citations

Amino acid substitutions within the matrix protein of type D retroviruses affect assembly, transport and membrane association of a capsid.

1991 • 92 citations

Feline Leukaemia Virus: Generation of Pathogenic and Oncogenic Variants

1991 • 91 citations

Transcription factors AP-3 and AP-2 interact with the SV40 enhancer in a mutually exclusive manner.

1989 • 90 citations

Mutations in the gag gene of Moloney murine leukemia virus: effects on production of virions and reverse transcriptase

1984 • 89 citations

Mechanism of release of the avian retrovirus tRNATrp primer molecule from viral DNA by ribonuclease H during reverse transcription

1982 • 88 citations

Defining nucleic acid-binding properties of avian retrovirus integrase by deletion analysis

1991 • 87 citations

Ubiquitin in avian leukosis virus particles

1990 • 85 citations

Construction and analysis of deletion mutations in the U5 region of Moloney murine leukemia virus: effects on RNA packaging and reverse transcription

1989 • 85 citations

Replication and regulation of primate foamy viruses

1991 • 85 citations

At least two nuclear proteins bind specifically to the Rous sarcoma virus long terminal repeat enhancer.

1987 • 83 citations

Isolation and characterization of a cDNA clone for the CCAAT transcription factor EFIA reveals a novel structural motif.

1990 • 82 citations

Genomic organization and expression of simian foamy virus type 3 (SFV-3)

1992 • 82 citations

Viral and cellular factors governing hamster cell infection by murine and gibbon ape leukemia viruses

1991 • 81 citations

It is Rous Sarcoma virus protein P12 and not P19 that binds tightly to Rous Sarcoma virus RNA

1984 • 80 citations

O-linked glycosylation of retroviral envelope gene products

1988 • 80 citations

Abortive reverse transcription by mutants of Moloney murine leukemia virus deficient in the reverse transcriptase-associated RNase H function

1991 • 79 citations

Characterization of Rous sarcoma virus intronic sequences that negatively regulate splicing

1991 • 79 citations

In vitro synthesis of infectious DNA of murine leukaemia virus

1977 • 78 citations

Virus-coded origin of a 32,000-dalton protein from avian retrovirus cores: structural relatedness of p32 and the beta polypeptide of the avian retrovirus DNA polymerase

1978 • 77 citations

When the Melting and Freezing Points are not the Same

1990 • 77 citations

Mutations within the proteolytic cleavage site of the Rous sarcoma virus glycoprotein that block processing to gp85 and gp37

1987 • 77 citations

Retroviral-Mediated Gene Transfer

1990 • 77 citations

Role of the gag polyprotein precursor in packaging and maturation of Rous sarcoma virus genomic RNA

1990 • 77 citations

Multiple regions in the Rous sarcoma virus src gene intron act in cis to affect the accumulation of unspliced RNA

1989 • 76 citations

Avian myeloblastosis virus RNA is terminally redundant: Implications for the mechanism of retrovirus replication

1977 • 76 citations

Plasma membrane receptors for ecotropic murine retroviruses require a limiting accessory factor

1991 • 75 citations

Preassembled capsids of type D retroviruses contain a signal sufficient for targeting specifically to the plasma membrane

1990 • 74 citations

Inhibition of RNase H activity and viral replication by single mutations in the 3' region of Moloney murine leukemia virus reverse transcriptase

1989 • 74 citations

Purification and properties of Rauscher leukemia virus DNA polymerase and selective inhibition of mammalian viral reverse transcriptase by inorganic phosphate.

1977 • 74 citations

The preparation and biochemical characterization of intact capsids of equine infectious anemia virus

1989 • 73 citations

Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells

1987 • 73 citations

Virion-Associated RNA Primer for Rous Sarcoma Virus DNA Synthesis: Isolation from Uninfected Cells

1974 • 71 citations

Basolateral maturation of retroviruses in polarized epithelial cells

1983 • 71 citations

Revisions of K/Ar ages for the Hadar hominid site, Ethiopia

1982 • 71 citations

Intronic sequences and 3' splice sites control Rous sarcoma virus RNA splicing

1992 • 71 citations

Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes in transgenic mice.

1988 • 70 citations

Molecular cloning and characterization of a novel human gene homologous to the murine ecotropic retroviral receptor

1991 • 70 citations

Inheritance and Expression of Chicken Genes That Are Related to Avian Leukosis Sarcoma Virus Genes

1978 • 70 citations

Binding of SL3-3 enhancer factor 1 transcriptional activators to viral and chromosomal enhancer sequences

1991 • 70 citations

Virus-Host Interactions and the Pathogenesis of Murine and Human Oncogenic Retroviruses

1991 • 69 citations

RNA pseudoknots that interact with components of the translation apparatus

1989 • 69 citations

Ecotropic murine leukemia virus-induced fusion of murine cells

1986 • 68 citations

Occlusion of the HIV poly(A) site.

1991 • 68 citations

Structural role of the matrix protein of type D retroviruses in gag polyprotein stability and capsid assembly

1990 • 67 citations

Frameshift and intragenic suppressor mutations in a rous sarcoma provirus suggest src encodes two proteins

1983 • 66 citations

Specificity of initiation of plus-strand DNA by Rous sarcoma virus

1984 • 65 citations

Keeping the Computer Flag Flying

1971 • 64 citations

Enhancer activity correlates with the oncogenic potential of avian retroviruses.

1985 • 64 citations

The NH2-terminal sequence of the avian oncovirus gag precursor polyprotein (Pr76gag)

1978 • 64 citations

Analysis of retroviral pol gene products with antisera raised against fusion proteins produced in Escherichia coli

1986 • 63 citations

Insertional Mutagenesis in Mouse Mammary Tumorigenesis

1991 • 63 citations

Nucleotide sequence of the 5' noncoding region and part of the gag gene of Rous sarcoma virus

1982 • 62 citations

Gene Therapy

1990 • 62 citations

Simian retrovirus D serogroup 1 has a broad cellular tropism for lymphoid and nonlymphoid cells

1988 • 60 citations

Removal of 3'-OH-terminal nucleotides from blunt-ended long terminal repeat termini by the avian retrovirus integration protein

1990 • 58 citations

Nucleotide sequences of gag-pol regions that determine the Fv-1 host range property of BALB/c N-tropic and B-tropic murine leukemia viruses

1983 • 58 citations

Synthesis of a 600-nucleotide-long plus-strand DNA by virions of Moloney murine leukemia virus.

1979 • 57 citations

Retrovirus promoter-trap vector to induce lacZ gene fusions in mammalian cells

1991 • 57 citations

Identification of genes for reverse transcriptase–like enzymes in twoDrosophilaretrotransposons,412 and gypsy; a rapid detection method of reverse transcriptase genes using YXDD box probes

1986 • 55 citations

Genetic evidence that the avian retrovirus DNA endonuclease domain of pol is necessary for viral integration

1988 • 53 citations

Human Retroviruses, Cancer, and AIDS. Approaches to Prevention and Therapy

1988 • 53 citations

Insertion of several different DNAs in reticuloendotheliosis virus strain T suppresses transformation by reducing the amount of subgenomic mRNA

1986 • 53 citations

Synthesis and Processing of Avian Sarcoma Retrovirus RNA

1988 • 52 citations

Silent infection of murine embryonal carcinoma cells by moloney murine leukemia virus

1980 • 51 citations

Comparison of the small RNAs of polymerase-deficient and polymerase-positive Rous sarcoma virus and another species of avian retrovirus

1979 • 47 citations

Vaccination with a live retrovirus: the nature of the protective immune response.

1990 • 47 citations

The Human retroviruses

1991 • 47 citations

Gene product of moloney murine leukemia virus required for proviral integration is a DNA-binding protein

1988 • 47 citations

In situ processing of a retroviral nucleocapsid protein by the viral proteinase

1991 • 47 citations

Nonpolarized expression of a secreted murine leukemia virus glycoprotein in polarized epithelial cells

1986 • 46 citations

Characterization of Rous sarcoma virus sequences essential for viral gene expression

1987 • 44 citations

N myristoylation of the spleen necrosis virus matrix protein is required for correct association of the Gag polyprotein with intracellular membranes and for particle formation

1990 • 42 citations

Molecular domains involved in oligomerization of the friend murine leukemia virus envelope glycoprotein

1991 • 41 citations

Localization of the receptor gene for type D simian retroviruses on human chromosome 19

1990 • 41 citations

Isolation of embryonal carcinoma cell lines that express integrated recombinant genes flanked by the Moloney murine leukemia virus long terminal repeat.

1985 • 40 citations

Infectious entry of murine retroviruses into mouse cells: evidence of a postadsorption step inhibited by acidic pH

1985 • 40 citations

Two distant upstream regions containing cis-acting signals regulating splicing facilitate 3'-end processing of avian sarcoma virus RNA

1992 • 40 citations

Characterization of monoclonal antibodies against the human immunodeficiency virus matrix protein, p17gag: identification of epitopes exposed at the surfaces of infected cells

1991 • 39 citations

Monoclonal antibody to the amino-terminal L sequence of murine leukemia virus glycosylated gag polyproteins demonstrates their unusual orientation in the cell membrane

1986 • 38 citations

trans-acting viral protease is necessary and sufficient for activation of avian leukosis virus reverse transcriptase

1991 • 36 citations

Retroviral gag gene amber codon suppression is caused by an intrinsic cis-acting component of the viral mRNA

1988 • 34 citations

Rearrangements in unintegrated retroviral DNA are complex and are the result of multiple genetic determinants

1990 • 33 citations

cDNA sequence and genomic characterization of intracisternal A-particle-related retroviral elements containing an envelope gene

1991 • 33 citations

Noncoding region between the env and src genes of Rous sarcoma virus influences splicing efficiency at the src gene 3' splice site

1987 • 33 citations

A cellular enhancer of retrovirus gene expression in embryonal carcinoma cells.

1987 • 29 citations

Polycistronic Animal Virus mRNAs

1989 • 28 citations

Retrovirus variation and evolution

1989 • 28 citations

Efficient transformation by Prague A Rous sarcoma virus plasmid DNA requires the presence of cis-acting regions within the gag gene

1987 • 25 citations

An X-Linked Gene Affecting Mouse Cell DNA Synthesis Also Affects Production of Unintegrated Linear and Supercoiled DNA of Murine Leukemia Virus

1984 • 24 citations

Cauliflower mosaic virus replication intermediates are encapsidated into virion-like particles

1987 • 24 citations

Avian sarcoma-leukosis virus pol-endo proteins expressed independently in mammalian cells accumulate in the nucleus but can be directed to other cellular compartments

1988 • 20 citations

An enhancer sequence instability that diversifies the cell repertoire for expression of a murine leukemia virus

1988 • 19 citations

Retroviruses: strategies of replication.

1990 • 17 citations

Lysine-329 of murine leukemia virus reverse transcriptase: possible involvement in the template-primer binding function

1990 • 16 citations

Retroviral Insertion and Oncogene Activation

1991 • 16 citations

Retroviruses and Disease

1989 • 14 citations

Transient expression analysis of the reticuloendotheliosis virus long terminal repeat element

1989 • 13 citations

Functions of Murine Leukemia Virus Envelope Gene Products in Leukemogenesis

1989 • 12 citations

Hepadnaviruses : molecular biology and pathogenesis

1991 • 12 citations

An X-linked gene affecting mouse cell DNA synthesis also affects production of unintegrated linear and supercoiled DNA of murine leukemia virus.

1984 • 11 citations

Photoaffinity labeling of the primer binding domain in murine leukemia virus reverse transcriptase

1991 • 10 citations

Molecular biology and pathogenesis of mouse mammary tumour virus

1991 • 4 citations

Receptors for Human Retroviruses

1991 • 3 citations

Genome Project

1988 • 3 citations