Enhancement of SIV Infection with Soluble Receptor Molecules

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

Isolation of T-Cell Tropic HTLV-III-Like Retrovirus from Macaques

1985 • 929 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

An African primate lentivirus (SIVsmclosely related to HIV-2

1989 • 750 citations

Major Glycoprotein Antigens That Induce Antibodies in AIDS Patients Are Encoded by HTLV-III

1985 • 583 citations

Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses

1987 • 543 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

Blocking of HIV-1 Infectivity by a Soluble, Secreted Form of the CD4 Antigen

1987 • 485 citations

HIV infection is blocked in vitro by recombinant soluble CD4

1988 • 446 citations

Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus

1987 • 433 citations

HTLV-III-neutralizing antibodies in patients with AIDS and AIDS-related complex

1985 • 427 citations

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1988 • 425 citations

Isolation of an HTLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabeys

1986 • 419 citations

Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells

1989 • 405 citations

Soluble CD4 molecules neutralize human immunodeficiency virus type 1

1988 • 403 citations

Epitopes of the CD4 Antigen and HIV Infection

1986 • 379 citations

Alterations in T4 (CD4) Protein and mRNA Synthesis in Cells Infected with HIV

1986 • 360 citations

Identification of the residues in human CD4 critical for the binding of HIV

1989 • 357 citations

Sequence of simian immunodeficiency virus from African green monkey, a new member of the HIV/SIV group

1988 • 336 citations

Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys).

1986 • 313 citations

Variable and conserved neutralization antigens of human immunodeficiency virus

1986 • 296 citations

Isolation of simian immunodeficiency virus from african green monkeys and seroepidemiologic survey of the virus in various non‐human primates

1988 • 284 citations

Serologic Identification and Characterization of a Macaque T-Lymphotropic Retrovirus Closely Related to HTLV-III

1985 • 265 citations

Induction of anti-HIV neutralizing antibodies by synthetic peptides.

1986 • 237 citations

Isolation and characterization of simian immunodeficiency virus from mandrills in Africa and its relationship to other human and simian immunodeficiency viruses

1988 • 163 citations

Simian immunodeficiency virus from African green monkeys

1988 • 126 citations

Biological characterization of a simian immunodeficiency virus-like retrovirus (HTLV-IV): evidence for CD4-associated molecules required for infection

1988 • 103 citations

Purified envelope glycoproteins from human immunodeficiency virus type 1 variants induce individual, type-specific neutralizing antibodies

1988 • 85 citations

Mode of Insertion into a Lipid Membrane of the N-Terminal HIV gp41 Peptide Segment

1988 • 64 citations

Isolation and Characterization of Simian Immunodeficiency Viruses from Two Subspecies of African Green Monkeys

1990 • 53 citations