Simian immunodeficiency virus (SIV) infection of infant rhesus macaques as a model to test antiretroviral drug prophylaxis and therapy: oral 3'-azido-3'-deoxythymidine prevents SIV infection

A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12

1938 • 19,183 citations

A simple method of estimating 50 per cent end points

1938 • 8,381 citations

The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex

1987 • 3,000 citations

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

1985 • 1,830 citations

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

1986 • 1,348 citations

Zidovudine in Asymptomatic Human Immunodeficiency Virus Infection

1990 • 1,288 citations

Quantitation of Human Immunodeficiency Virus Type 1 in the Blood of Infected Persons

1989 • 1,090 citations

Transient High Levels of Viremia in Patients with Primary Human Immunodeficiency Virus Type 1 Infection

1991 • 851 citations

Reversibility by dipyridamole of thallium-201 myocardial scan defects in patients with sarcoidosis

1988 • 366 citations

Inactivated simian immunodeficiency virus vaccine failed to protect rhesus macaques from intravenous or genital mucosal infection but delayed disease in intravenously exposed animals

1990 • 131 citations

Management of Occupational Exposures to Bloodborne Pathogens: Hepatitis B Virus, Hepatitis C Virus, and Human Immunodeficiency Virus

1992 • 86 citations

Nonhuman Primate Models for Evaluation of AIDS Therapy^a

1990 • 67 citations

Simian and feline immunodeficiency viruses: Animal lentivirus models for evaluation of AIDS vaccines and antiviral agents

1991 • 66 citations

Postexposure chemoprophylaxis with ZDV or ZDV combined with interferon-alpha: failure after inoculating rhesus monkeys with a high dose of SIV.

1991 • 55 citations

Efficacy of live‐attenuated and whole‐inactivated simian immunodeficiency virus vaccines against vaginal challenge with virulent SIV

1992 • 55 citations

Development of simian immunodeficiency virus isolation, titration, and neutralization assays which use whole blood from rhesus monkeys and an antigen capture enzyme-linked immunosorbent assay

1991 • 52 citations

Antiviral effects of 3'-fluorothymidine and 3'-azidothymidine in cynomolgus monkeys infected with simian immunodeficiency virus.

1991 • 46 citations

Quantitation of human immunodeficiency virus in vertically infected infants and children

1991 • 43 citations

Immunogenicity of Haemophilus Influenzae Type b Conjugate Vaccines in Infant Rhesus Monkeys

1991 • 31 citations

Detection of simian immunodeficiency virus DNA in macrophages from infected rhesus macaques

1992 • 28 citations

Pharmacokinetics of zidovudine (azidothymidine). II. Development of metabolic and renal clearance pathways in the neonate.

1990 • 27 citations

Simple and rapid high-performance liquid chromatographic assay for zidovudine (azidothymidine) in plasma and urine

1988 • 26 citations

Quantitation of HIV: Correlation with clinical, virological, and immunological status

1991 • 25 citations

Specific routine determination of 3'-azido-3'-deoxythymidine (AZT) in plasma by partly automated liquid chromatography.

1989 • 21 citations

In Vitro Testing of Therapeutics against SIV and HIV

1990 • 3 citations