Cellular factors regulate transactivation of human immunodeficiency virus type 1

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

1987 • 902 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Activation of the AIDS Retrovirus Promoter by the Cellular Transcription Factor, Sp1

1986 • 741 citations

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1986 • 730 citations

Characterization of EBV‐genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non‐Hodgkin lymphoma

1977 • 698 citations

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

1987 • 672 citations

The trans-activator gene of HTLV-III is essential for virus replication

1986 • 635 citations

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

1986 • 615 citations

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

1989 • 577 citations

Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses.

1986 • 368 citations

Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.

1989 • 357 citations

Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III

1986 • 325 citations

Immediate-early gene region of human cytomegalovirus trans-activates the promoter of human immunodeficiency virus.

1987 • 317 citations

Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element

1989 • 311 citations

Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus.

1987 • 306 citations

Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virus.

1986 • 303 citations

Expression and Characterization of the Trans -Activator of HTLV-III/LAV Virus

1986 • 276 citations

Structural arrangements of transcription control domains within the 5'-untranslated leader regions of the HIV-1 and HIV-2 promoters.

1988 • 271 citations

Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1

1985 • 270 citations

TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter

1990 • 253 citations

trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus

1988 • 237 citations

Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

1990 • 236 citations

A cDNA for a Protein That Interacts with the Human Immunodeficiency Virus Tat Transactivator

1990 • 234 citations

Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoter

1987 • 223 citations

Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region

1989 • 216 citations

Purification of the human immunodeficiency virus type 1 enhancer and TAR binding proteins EBP-1 and UBP-1.

1988 • 201 citations

Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains

1990 • 197 citations

A Rapid, Sensitive, and Inexpensive Assay for Chloramphenicol Acetyltransferase

1987 • 196 citations

ADENOVIRUS E1A PROTEIN PARADIGM VIRAL TRANSACTIVATOR

1989 • 184 citations

HIV and HCMV coinfect brain cells in patients with AIDS

1988 • 180 citations

Mutational analysis of the 5′ non-coding region of human immunodeficiency virus type 1: effects of secondary structure on translation.

1988 • 168 citations

Production of mouse mammary tumor virus by cultured cells in the absence and presence of hormones: Assay by molecular hybridization

1975 • 162 citations

Transcriptional but not translational regulation of HIV-1 by the tat gene product

1988 • 158 citations

HIV-1 TAT “activates” presynthesized RNA in the nucleus

1989 • 135 citations

Human Chromosome 12 Is Required for Elevated HIV-1 Expression in Human-Hamster Hybrid Cells

1989 • 109 citations

Differences in Cell Type-specific Blocks to Immediate Early Gene Expression and DNA Replication of Human, Simian and Murine Cytomegalovirus

1988 • 109 citations

Expression of the acidic nuclear immediate-early protein (IE1) of human cytomegalovirus in stable cell lines and its preferential association with metaphase chromosomes

1989 • 99 citations

Human chromosome 12 encodes a species-specific factor which increases human immunodeficiency virus type 1 tat-mediated trans activation in rodent cells

1990 • 94 citations

A nuclear translational block imposed by the HIV-1 U3 region is relieved by the Tat-TAR interaction

1990 • 86 citations

Cytomegalovirus activates transcription directed by the long terminal repeat of human immunodeficiency virus type 1

1990 • 83 citations

Regulation of human T cell leukemia virus expression ¹

1990 • 78 citations

Molecular biology of HIV

1989 • 75 citations

Alterations in binding characteristics of the human immunodeficiency virus enhancer factor

1988 • 67 citations

Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region

1989 • 47 citations

Simian foamy virus type 1 is a retrovirus which encodes a transcriptional transactivator

1990 • 42 citations

Transacting transcriptional activation of human spumaretrovirus LTR in infected cells

1990 • 31 citations

Molecular Interactions of Cytomegalovirus and the Human and Simian Immunodeficiency Viruses

1990 • 14 citations