Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

Active human immunodeficiency virus protease is required for viral infectivity.

1988 • 1,309 citations

Nucleotide sequence of the AIDS virus, LAV

1985 • 1,225 citations

Conserved Folding in Retroviral Proteases: Crystal Structure of Synthetic HIV-1 Protease

1989 • 1,155 citations

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

1988 • 936 citations

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

1989 • 883 citations

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1.

1989 • 831 citations

Nucleotide Sequence and Expression of an AIDS-Associated Retrovirus (ARV-2)

1985 • 718 citations

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

1985 • 706 citations

A structural model for the retroviral proteases

1987 • 594 citations

Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity

1989 • 373 citations

Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A.

1988 • 327 citations

The gag gene products of human immunodeficiency virus type 1: alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag precursors

1988 • 310 citations

Human immunodeficiency virus protease expressed in Escherichia coli exhibits autoprocessing and specific maturation of the gag precursor.

1987 • 285 citations

HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

1988 • 269 citations

A deletion mutation in the 5' part of the pol gene of Moloney murine leukemia virus blocks proteolytic processing of the gag and pol polyproteins

1985 • 249 citations

Murine leukemia virus maturation: Protease region required for conversion from “immature” to “Mature” core form and for virus infectivity

1985 • 231 citations

Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion.

1987 • 220 citations

Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24

1988 • 203 citations

AIDS in 1988.

1988 • 183 citations

Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease.

1989 • 180 citations

Peptide substrates and inhibitors of the HIV-1 protease

1989 • 162 citations

AIDS in 1988

1988 • 134 citations

Immunological and Chemical Analysis of P6, the Carboxyl-Terminal Fragment of HIV P15

1987 • 104 citations

Synthetic and enzyme inhibition studies of pepstatin analogs containing hydroxyethylene and ketomethylene dipeptide isosteres

1987 • 65 citations

Respiratory syncytial virus glycoproteins

1983 • 54 citations

Human Retroviruses, Cancer, and AIDS. Approaches to Prevention and Therapy

1988 • 53 citations

Human retroviruses, cancer and aids: Approaches to prevention and therapy

1987 • 23 citations