Interleukin‐10 in viral diseases and cancer: exiting the labyrinth?

Interleukin-10 and the Interleukin-10 Receptor

2001 • 6,422 citations

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

2003 • 4,529 citations

Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

2004 • 3,766 citations

Enhancement of Antitumor Immunity by CTLA-4 Blockade

1996 • 3,585 citations

N<scp>aturally</scp>A<scp>rising</scp>CD4⁺R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

2003 • 3,323 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Toll Pathway-Dependent Blockade of CD4 ⁺ CD25 ⁺ T Cell-Mediated Suppression by Dendritic Cells

2003 • 2,023 citations

Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2

1996 • 1,987 citations

Recognition of single-stranded RNA viruses by Toll-like receptor 7

2004 • 1,777 citations

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

2002 • 1,733 citations

AN INVESTIGATION OF POLYMORPHISM IN THE INTERLEUKIN‐10 GENE PROMOTER

1997 • 1,730 citations

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

2000 • 1,644 citations

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

2003 • 1,564 citations

Induction of Tumor Immunity by Removing CD25+CD4+ T Cells: A Common Basis Between Tumor Immunity and Autoimmunity

1999 • 1,475 citations

Modulation of tryptophan catabolism by regulatory T cells

2003 • 1,323 citations

Induction of tolerance by IL-10-treated dendritic cells.

1997 • 1,263 citations

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

2002 • 1,160 citations

Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

1990 • 1,155 citations

Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

2001 • 1,126 citations

Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

1999 • 1,066 citations

I<scp>nterleukin</scp>-10<scp>and</scp>R<scp>elated</scp>C<scp>ytokines and</scp>R<scp>eceptors</scp>

2004 • 1,063 citations

Potential Regulatory Function of Human Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase

2002 • 1,035 citations

IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy

2003 • 911 citations

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

2004 • 834 citations

Genetic influence on cytokine production and fatal meningococcal disease

1997 • 814 citations

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

2001 • 751 citations

Foxp3 Expressing CD4+CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells

2004 • 680 citations

Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production.

1995 • 676 citations

Generation of Human CD8 T Regulatory Cells by CD40 Ligand–activated Plasmacytoid Dendritic Cells

2002 • 659 citations

Natural and Induced CD4+CD25+ Cells Educate CD4+CD25− Cells to Develop Suppressive Activity: The Role of IL-2, TGF-β, and IL-10

2004 • 657 citations

IL-10-Secreting Regulatory T Cells Do Not Express Foxp3 but Have Comparable Regulatory Function to Naturally Occurring CD4+CD25+ Regulatory T Cells

2004 • 654 citations

Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

2001 • 644 citations

STAT proteins: From normal control of cellular events to tumorigenesis

2003 • 603 citations

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

2004 • 603 citations

Inhibition of the Differentiation of Dendritic Cells From CD34+ Progenitors by Tumor Cells: Role of Interleukin-6 and Macrophage Colony-Stimulating Factor

1998 • 576 citations

Effect of interleukin‐10 on dendritic cell maturation and function

1997 • 571 citations

Regulatory Activity of Autocrine IL-10 on Dendritic Cell Functions

2001 • 562 citations

A Role for TGF-β in the Generation and Expansion of CD4+CD25+ Regulatory T Cells from Human Peripheral Blood

2001 • 540 citations

Role of Transforming Growth Factor-beta Signaling in Cancer

2000 • 525 citations

Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence.

2003 • 516 citations

IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages

1998 • 505 citations

Sustained Dysfunction of Antiviral CD8⁺T Lymphocytes after Infection with Hepatitis C Virus

2001 • 496 citations

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease

2000 • 495 citations

Interleukin 10 secretion in relation to human IL-10 locus haplotypes

1998 • 478 citations

Specific Inhibition of Cyclooxygenase 2 Restores Antitumor Reactivity by Altering the Balance of IL-10 and IL-12 Synthesis

2000 • 474 citations

Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus

2000 • 464 citations

The dual role of IL-10

2002 • 453 citations

Persistent Toll-like receptor signals are required for reversal of regulatory T cell–mediated CD8 tolerance

2004 • 433 citations

Quantitative analysis of hepatitis C virus-specific CD8⁺T cells in peripheral blood and liver using peptide-MHC tetramers

1999 • 421 citations

A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses.

1995 • 415 citations

IL-10 is a key cytokine in psoriasis. Proof of principle by IL-10 therapy: a new therapeutic approach.

1998 • 414 citations

Tumor suppressor activity of the TGF-β pathway in human cancers

1996 • 412 citations

IL-10: a novel cytotoxic T cell differentiation factor.

1991 • 391 citations

Murine retroviruses activate B cells via interaction with toll-like receptor 4

2002 • 388 citations

Human immunodeficiency virus–driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients

2004 • 387 citations

Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy

2004 • 386 citations

Interleukin-10 Receptor Signaling through the JAK-STAT Pathway

1999 • 384 citations

Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma

1997 • 384 citations

TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells.

1999 • 379 citations

Prostaglandin E2 Induces the Final Maturation of IL-12-Deficient CD1a+CD83+ Dendritic Cells: The Levels of IL-12 Are Determined During the Final Dendritic Cell Maturation and Are Resistant to Further Modulation

1998 • 379 citations

IL-10, a novel growth cofactor for mature and immature T cells.

1990 • 371 citations

The host—tumor immune conflict: from immunosuppression to resistance and destruction

1997 • 363 citations

Interleukin 10 treatment reduces fibrosis in patients with chronic hepatitis C: A pilot trial of interferon nonresponders

2000 • 358 citations

CD4+CD25+ Regulatory T Cells Control the Severity of Viral Immunoinflammatory Lesions

2004 • 357 citations

TIR domain-containing adaptors define the specificity of TLR signaling

2003 • 345 citations

Reversal of Tumor-induced Dendritic Cell Paralysis by CpG Immunostimulatory Oligonucleotide and Anti–Interleukin 10 Receptor Antibody

2002 • 340 citations

Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer.

2003 • 332 citations

IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response.

1995 • 326 citations

Bacteria-triggered CD4+ T Regulatory Cells Suppress Helicobacter hepaticus–induced Colitis

2002 • 324 citations

Tumor Cell Responses to IFNγ Affect Tumorigenicity and Response to IL-12 Therapy and Antiangiogenesis

1998 • 324 citations

Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo.

1999 • 315 citations

Hepatic expansion of a virus-specific regulatory CD8+ T cell population in chronic hepatitis C virus infection

2004 • 303 citations

TGF-β1 Prevents the Noncognate Maturation of Human Dendritic Langerhans Cells

1999 • 303 citations

CD4+ CD25+ Regulatory T Lymphocytes Inhibit Microbially Induced Colon Cancer in Rag2-Deficient Mice

2003 • 300 citations

Inhibition of interleukin 10 by rituximab results in down-regulation of bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis.

2001 • 287 citations

Immunoregulatory cytokines in chronic hepatitis C virus infection: Pre- and posttreatment with interferon alfa

1996 • 281 citations

Human non-small cell lung cancer cells express a type 2 cytokine pattern

1996 • 263 citations

IDO and tolerance to tumors

2003 • 262 citations

Class II cytokine receptors and their ligands: Key antiviral and inflammatory modulators

2003 • 257 citations

A Transgenic Model to Analyze the Immunoregulatory Role of IL-10 Secreted by Antigen-Presenting Cells

1999 • 257 citations

Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma

2002 • 253 citations

Production of IL‐10 by melanoma cells: Examination of its role in immunosuppression mediated by melanoma

1994 • 248 citations

Serum interleukin-10 in non-Hodgkin's lymphoma: a prognostic factor

1993 • 239 citations

Interleukin-10 is a growth factor for human melanoma cells and down-regulates HLA class-I, HLA class-II and ICAM-1 molecules

1997 • 239 citations

Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies.

1992 • 235 citations

Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism.

1996 • 227 citations

Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy

1999 • 223 citations

Tumour escape from immune surveillance through dendritic cell inactivation

2002 • 221 citations

Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40‐ligand) and TNF‐α, but strongly enhanced by interleukin‐10

1995 • 215 citations

Induction of a Novel Cellular Homolog of Interleukin-10, AK155, by Transformation of T Lymphocytes with Herpesvirus Saimiri

2000 • 210 citations

Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice.

1996 • 207 citations

CD4(+)CD25(+) regulatory lymphocytes require interleukin 10 to interrupt colon carcinogenesis in mice.

2003 • 206 citations

Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells

1994 • 205 citations

Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells.

1997 • 200 citations

CpG-matured Murine Plasmacytoid Dendritic Cells Are Capable of In Vivo Priming of Functional CD8 T Cell Responses to Endogenous but Not Exogenous Antigens

2004 • 198 citations

Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages.

1997 • 197 citations

Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration.

1997 • 196 citations

Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors.

1996 • 195 citations

Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells

2004 • 194 citations

Regulatory T cells

2004 • 194 citations

Contribution of Natural Killer Cells to Inhibition of Angiogenesis by Interleukin-12

1999 • 192 citations

Interleukin-10 promotes the maintenance of antitumor CD8+ T-cell effector function in situ

2001 • 191 citations

Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect

2003 • 188 citations

IL-10 and TGF- induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

2003 • 185 citations

Generation of antitumor immunity by cytotoxic T lymphocyte epitope peptide vaccination, CpG-oligodeoxynucleotide adjuvant, and CTLA-4 blockade.

2003 • 181 citations

Local release of IL-10 by transfected mouse mammary adenocarcinoma cells does not suppress but enhances antitumor reaction and elicits a strong cytotoxic lymphocyte and antibody-dependent immune memory.

1995 • 180 citations

Cutting Edge: IL-26 Signals through a Novel Receptor Complex Composed of IL-20 Receptor 1 and IL-10 Receptor 2

2004 • 166 citations

Epstein-Barr virus--associated diseases in humans.

2000 • 163 citations

Regulation of Tumor Growth and Metastasis by Interleukin-10: The Melanoma Experience

1999 • 161 citations

Non-small cell lung cancer-derived soluble mediators and prostaglandin E2 enhance peripheral blood lymphocyte IL-10 transcription and protein production.

1996 • 160 citations

Antimetastatic and Antitumor Activities of Interleukin 10 in a Murine Model of Breast Cancer

1996 • 157 citations

Interleukin-10 Inhibits Activation of Coagulation and Fibrinolysis During Human Endotoxemia

1997 • 156 citations

Interleukin-10 is an autocrine growth factor for acquired immunodeficiency syndrome-related B-cell lymphoma [see comments]

1995 • 156 citations

Interleukin 10 Treatment of Psoriasis

1999 • 155 citations

Polymorphism of the Interleukin‐10 Gene Is Associated with Susceptibility to Epstein‐Barr Virus Infection

1999 • 152 citations

Interleukin‐10 inhibits the primary allogeneic T cell response to human epidermal Langerhans cells

1994 • 151 citations

Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10.

2003 • 145 citations

Immature anti-inflammatory response in neonates

2003 • 144 citations

IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences

2003 • 140 citations

Interleukin 10 transfected into Chinese hamster ovary cells prevents tumor growth and macrophage infiltration.

1993 • 140 citations

Quantitative analysis of Th1, Th2 and TGF-β1 cytokine expression in tumor, TIL and PBL of non-small cell lung cancer patients

1998 • 139 citations

Elevated serum levels of interleukin-10 in patients with metastatic malignant melanoma

1995 • 138 citations

Respective involvement of TGF-β and IL-4 in the development of Langerhans cells and non-Langerhans dendritic cells from CD34+ progenitors

1999 • 136 citations

Contribution of Natural Killer Cells to Inhibition of Angiogenesis by Interleukin-12

1999 • 136 citations

Induction of FOXP3‐expressing regulatory CD4^pos T cells by human mature autologous dendritic cells

2004 • 135 citations

Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation

2004 • 135 citations

The Genome Sequence of Yaba-like Disease Virus, a Yatapoxvirus

2001 • 135 citations

IL-4 and IL-10 Antagonize IL-12-Mediated Protection Against Acute Vaccinia Virus Infection with a Limited Role of IFN-γ and Nitric Oxide Synthetase 2

2000 • 134 citations

Immunoregulatory roles of IL-10 in innate immunity: IL-10 inhibits macrophage production of IFN-gamma-inducing factors but enhances NK cell production of IFN-gamma.

1998 • 131 citations

Interleukin 10 (IL-10) inhibition of primary human prostate cell-induced angiogenesis: IL-10 stimulation of tissue inhibitor of metalloproteinase-1 and inhibition of matrix metalloproteinase (MMP)-2/MMP-9 secretion.

1999 • 130 citations

Realization of the therapeutic potential of CTLA-4 blockade in low-dose chemotherapy-treated tumor-bearing mice.

1998 • 129 citations

MDA-7/IL-24 is a unique cytokine–tumor suppressor in the IL-10 Family

2004 • 125 citations

A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice.

1997 • 125 citations

IL-10 Improves Skin Disease and Modulates Endothelial Activation and Leukocyte Effector Function in Patients with Psoriatic Arthritis

2001 • 122 citations

Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect

2003 • 121 citations

Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers*

1997 • 119 citations

Role of interleukin 10 and transforming growth factor beta1 in the angiogenesis and metastasis of human prostate primary tumor lines from orthotopic implants in severe combined immunodeficiency mice.

1999 • 116 citations

A Single Amino Acid Determines the Immunostimulatory Activity of Interleukin 10

2000 • 113 citations

Constitutive IL-10 Production Accounts for the High NK Sensitivity, Low MHC Class I Expression, and Poor Transporter Associated with Antigen Processing (TAP)-1/2 Function in the Prototype NK Target YAC-1

1998 • 113 citations

Susceptibility to Primary Epstein‐Barr Virus Infection Is Associated with Interleukin‐10 Gene Promoter Polymorphism

2001 • 112 citations

Immunoregulatory Roles of IL-10 in Innate Immunity: IL-10 Inhibits Macrophage Production of IFN-γ-Inducing Factors but Enhances NK Cell Production of IFN-γ

1998 • 111 citations

Advanced colorectal cancer is associated with impaired interleukin 12 and enhanced interleukin 10 production.

1998 • 109 citations

Distinct Transcriptional Programs Activated by Interleukin-10 with or without Lipopolysaccharide in Dendritic Cells: Induction of the B Cell-Activating Chemokine, CXC Chemokine Ligand 13

2004 • 109 citations

Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer.

2003 • 106 citations

Interleukin-10 production in malignant melanoma: Preferential detection of IL-10-secreting tumor cells in metastatic lesions

1996 • 105 citations

IL-10 Is a Central Regulator of Cyclooxygenase-2 Expression and Prostaglandin Production

2001 • 98 citations

IL-10 haplotypes as possible predictors of spontaneous clearance of HCV infection

2003 • 95 citations

Ammonium Trichloro(dioxoethylene-o,o′)tellurate (AS101) Sensitizes Tumors to Chemotherapy by Inhibiting the Tumor Interleukin 10 Autocrine Loop

2004 • 94 citations

Abolished angiogenicity and tumorigenicity of Burkitt lymphoma by interleukin-10

2000 • 91 citations

Identification of a novel thymocyte growth-promoting factor derived from B cell lymphomas

1990 • 88 citations

Cell activation by synthetic lipopeptides of the hepatitis C virus (HCV)—core protein is mediated by toll like receptors (TLRs) 2 and 4

2002 • 85 citations

Loss of Tumorigenicity and Increased Immunogenicity Induced by Interleukin-10 Gene Transfer in B16 Melanoma Cells

1996 • 83 citations

Interleukin‐1, interleukin‐10 and tumour necrosis factor‐alpha gene polymorphisms in hepatitis C virus infection: an investigation of the relationships with spontaneous viral clearance and response to alpha‐interferon therapy

2002 • 81 citations

Interleukin 10 treatment of patients with rheumatoid arthritis enhances Fc gamma receptor expression on monocytes and responsiveness to immune complex stimulation.

2003 • 79 citations

IL-10 converts mouse lymphoma cells to a CTL-resistant, NK-sensitive phenotype with low but peptide-inducible MHC class I expression.

1995 • 73 citations

Clinical and Immunologic Assessment of Patients With Psoriasis in a Randomized, Double-blind, Placebo-Controlled Trial Using Recombinant Human Interleukin 10

2002 • 67 citations

IL-10 expression by CT26 colon carcinoma cells inhibits their malignant phenotype and induces a T cell-mediated tumor rejection in the context of a systemic Th2 response

1999 • 66 citations

Polymorphism of the IL-10 Gene is Associated with Susceptibility to Herpes Zoster

2002 • 65 citations

IL-10-Conditioned Dendritic Cells, Decommissioned for Recruitment of Adaptive Immunity, Elicit Innate Inflammatory Gene Products in Response to Danger Signals

2004 • 65 citations

The Role of IL-10 in Mouse Hepatitis Virus-Induced Demyelinating Encephalomyelitis

1998 • 60 citations

A PILOT TRIAL OF RECOMBINANT HUMAN INTERLEUKIN-10 IN KIDNEY TRANSPLANT RECIPIENTS RECEIVING OKT3 INDUCTION THERAPY1,2

1997 • 56 citations

Effects of virally expressed interleukin-10 on vaccinia virus infection in mice

1993 • 56 citations

Kinetics of cytokine expression in melanoma metastases classifies immune responsiveness

2001 • 55 citations

Serum levels of interleukin-10 in patients with diffuse large cell lymphoma: lack of correlation with prognosis [see comments]

1995 • 52 citations

Local release of interleukin-10 by transfected mouse adenocarcinoma cells exhibits pro- and anti-inflammatory activity and results in a delayed tumor rejection.

1998 • 50 citations

Clinical implications of cytokine and soluble receptor measurements in patients with newly‐diagnosed aggressive non‐Hodgkin's lymphoma

1995 • 49 citations

Interleukin 10-induced thrombocytopenia in normal healthy adult volunteers: evidence for decreased platelet production

2000 • 48 citations

Importance of IL-10 for CTLA-4-Mediated Inhibition of Tumor-Eradicating Immunity

2004 • 47 citations

Two Distinct Pathways of Immuno-Modulation Improve Potency of p53 Immunization in Rejecting Established Tumors

2004 • 47 citations

Interleukin-10 Enhances the Therapeutic Effectiveness of a Recombinant Poxvirus-Based Vaccine in an Experimental Murine Tumor Model

1999 • 46 citations

DIFFERENTIAL EFFECTS OF MYELOID DENDRITIC CELLS RETROVIRALLY TRANSDUCED TO EXPRESS MAMMALIAN OR VIRAL INTERLEUKIN-10 ON CYTOTOXIC T LYMPHOCYTE AND NATURAL KILLER CELL FUNCTIONS AND RESISTANCE TO TUMOR GROWTH1,2

2001 • 33 citations

Murine gammaherpesvirus‐68‐induced interleukin‐10 increases viral burden, but limits virus‐induced splenomegaly and leukocytosis

2001 • 31 citations

A Pilot Study of Daily Subcutaneous Interleukin-10 in Patients with Chronic Hepatitis C Infection

1999 • 29 citations

A multicenter, randomized, double-blind, placebo-controlled trial of recombinant human interleukin-10 in HIV-infected subjects

2000 • 27 citations

In VivoEffects of IL-4, IL-10, and Amifostine on Cytokine Production in Patients with Acute Myelogenous Leukemia

2001 • 18 citations

Effects of single intravenous doses of recombinant human interleukin-10 on subsets of circulating leukocytes in humans

1999 • 16 citations

Interleukin 10‐induced thrombocytopenia in normal healthy adult volunteers: evidence for decreased platelet production

2000 • 9 citations