Induction of FOXP3‐expressing regulatory CD4pos T cells by human mature autologous dendritic cells

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

1995 • 2,531 citations

Decoding the Patterns of Self and Nonself by the Innate Immune System

2002 • 2,096 citations

Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

2001 • 1,845 citations

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

2001 • 1,659 citations

Induction of Interleukin 10–Producing, Nonproliferating Cd4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic Cells

2000 • 1,577 citations

Antigen-Specific Inhibition of Effector T Cell Function in Humans after Injection of Immature Dendritic Cells

2001 • 1,384 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 1,252 citations

Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance

2002 • 1,176 citations

Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability

1996 • 1,138 citations

Sequence analysis of peptides bound to MHC class II molecules

1991 • 1,071 citations

Selecting and maintaining a diverse T-cell repertoire

1999 • 712 citations

Antigen-dependent Proliferation of CD4+ CD25+ Regulatory T Cells In Vivo

2003 • 600 citations

Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype

2003 • 582 citations

Continuous Activation of Autoreactive CD4+ CD25+ Regulatory T Cells in the Steady State

2003 • 523 citations

Inaugural Article : avoiding horror autotoxicus. The importance of dendritic cells in peripheral T cell tolerance

2002 • 448 citations

Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway.

1997 • 443 citations

Regulatory T cells under scrutiny

2003 • 427 citations

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

2002 • 390 citations

Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion.

1996 • 330 citations

Contribution of dendritic cells to stimulation of the murine syngeneic mixed leukocyte reaction.

1980 • 329 citations

Antigen-induced regulatory T cells in autoimmunity

2003 • 317 citations

High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes

1997 • 292 citations

Functional antigen-independent synapses formed between T cells and dendritic cells

2001 • 287 citations

Prevention of Type I Diabetes in NOD Mice by Adjuvant Immunotherapy

1990 • 264 citations

Failure of autologous mixed lymphocyte reactions between T and non-T cells in patients with systemic lupus erythematosus.

1978 • 236 citations

Lymphocyte transformation induced by autologous cells. V. generation of immunologic memory and specificity during the autologous mixed lymphocyte reaction

1977 • 215 citations

Cytokine mRNA quantification by real-time PCR

2002 • 212 citations

Immunotherapy of NOD mice with bone marrow-derived dendritic cells.

1999 • 184 citations

The origin of FOXP3-expressing CD4+ regulatory T cells: thymus or periphery

2003 • 179 citations

The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens

2003 • 177 citations

Specificity and Suppressor Function of Human T Cells Responsive to Autologous Non-T Cells

1979 • 148 citations

Induction of suppressor activity in the autologous mixed lymphocyte reaction and in cultures with concanavalin A.

1979 • 112 citations

Inhibition of Adjuvant Arthritis by a DNA Vaccine Encoding Human Heat Shock Protein 60

2002 • 107 citations

Peripheral Expression of Self-MHC-II Influences the Reactivity and Self-Tolerance of Mature CD4+ T Cells

2002 • 94 citations

Suppression of Autoimmune Disease in NZB and (NZB×NZW)F1 Hybrid Mice by Infection with Malaria

1970 • 92 citations

Highly Autoproliferative T Cells Specific for 60-kDa Heat Shock Protein Produce IL-4/IL-10 and IFN-γ and Are Protective in Adjuvant Arthritis

2000 • 72 citations

Initiation of the Autologous Mixed Lymphocyte Reaction Requires the Expression of Costimulatory Molecules B7-1 and B7-2 on Human Peripheral Blood Dendritic Cells

1998 • 65 citations

Defective suppressor cell generation in juvenile onset diabetes.

1981 • 58 citations

Bacterial agents protect against autoimmune disease. I. Mice pre-exposed to Bordetella pertussis or Mycobacterium tuberculosis are highly refractory to induction of experimental autoimmune encephalomyelitis

1992 • 56 citations

Surface molecules involved in self-recognition and T cell activation in the autologous mixed lymphocyte reaction.

1984 • 55 citations

T Cell Proliferation Induced by Autologous Non-T Cells Is a Response to Apoptotic Cells Processed by Dendritic Cells

2002 • 45 citations

Anergic T cells as active regulators of the immune response

2000 • 41 citations

Dendritic cells exposed to nacystelyn are refractory to maturation and promote the emergence of alloreactive regulatory T cells

2003 • 40 citations

The T-cell repertoire available for recognition of self-antigens

2001 • 32 citations

Human autologous mixed lymphocyte reaction as an in vitro model for autoreactivity to apoptotic antigens

2002 • 20 citations

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