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Phospholipase A2: Its Usefulness in Laboratory Diagnostics

Data up to Jan 2025

Published1999
Citations38
References644

Total Citations Per Year

Abstract

References (644)

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Membrane Fusion

1990 • 2,458 citations

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

1988 • 1,711 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Diversity of group types, regulation, and function of phospholipase A2.

1994 • 1,444 citations

Perspectives in platelet-activating factor research.

1987 • 1,383 citations

Multiple-Organ Failure

1985 • 1,314 citations

Hepatogastroenterology

2011 • 1,309 citations

Adriamycin: The Role of Lipid Peroxidation in Cardiac Toxicity and Tumor Response

1977 • 1,116 citations

Bacterial contamination of pancreatic necrosis

1986 • 926 citations

Platelet-activating factor.

1990 • 904 citations

The eicosanoids and their biochemical mechanisms of action

1989 • 882 citations

Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain

1970 • 854 citations

A phospholipase A2 inhibitory protein in rabbit neutrophils induced by glucocorticoids.

1980 • 841 citations

TUMOR NECROSIS, CACHEXIA, SHOCK, AND INFLAMMATION: A COMMON MEDIATOR

1988 • 814 citations

Properties and Regulation of Cytosolic Phospholipase A2

1997 • 814 citations

The growing phospholipase A2 superfamily of signal transduction enzymes

1997 • 811 citations

[Multiple organ failure syndrome].

1988 • 795 citations

PLATELET ACTIVATING FACTOR: A BIOLOGICALLY ACTIVE PHOSPHOGLYCERIDE

1986 • 781 citations

Renal filtration, transport, and metabolism of low-molecular-weight proteins: A review

1979 • 765 citations

Circulating Interleukin-1 and Tumor Necrosis Factor in Septic Shock and Experimental Endotoxin Fever

1990 • 765 citations

Clinical predictors of the adult respiratory distress syndrome

1982 • 684 citations

Structure and Properties of a Human Non-pancreatic Phospholipase A2

1989 • 668 citations

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis.

1988 • 655 citations

Pulmonary oxygen toxicity: a review.

1971 • 619 citations

Lipid-membrane interactions and the pathogenesis of ischemic damage in the myocardium.

1981 • 607 citations

Cytolytic and membrane-perturbing properties of lysophosphatidylcholine

1979 • 594 citations

Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.

1975 • 583 citations

Macrophages synthesise and release prostaglandins in response to inflammatory stimuli

1977 • 573 citations

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

1995 • 566 citations

Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells.

1976 • 555 citations

Role of phospholipases in generating lipid second messengers in signal transduction 1

1991 • 545 citations

Cloning and Recombinant Expression of Phospholipase A2 Present in Rheumatoid Arthritic Synovial Fluid

1989 • 542 citations

Albinism Associated with Hemorrhagic Diathesis and Unusual Pigmented Reticular Cells in the Bone Marrow: Report of Two Cases with Histochemical Studies

1959 • 539 citations

Purification and properties of phospholipase a from porcine pancreas

1968 • 537 citations

Cytosolic phospholipase A2

1995 • 530 citations

Biosynthesis of complex lipids.

1961 • 530 citations

Anti-inflammatory properties of a platelet-activating factor acetylhydrolase

1995 • 529 citations

Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells

1995 • 523 citations

Coenzyme A and carnitine distribution in normal and ischemic hearts.

1978 • 481 citations

Structure and function of phospholiphase A2

1981 • 478 citations

Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes.

1978 • 466 citations

Evidence of lung surfactant abnormality in respiratory failure. Study of bronchoalveolar lavage phospholipids, surface activity, phospholipase activity, and plasma myoinositol.

1982 • 461 citations

Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents.

1991 • 452 citations

Molecular cloning and expression of human Ca(2+)-sensitive cytosolic phospholipase A2

1991 • 447 citations

A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7.

1990 • 447 citations

Amphipathic metabolites and membrane dysfunction in ischemic myocardium.

1984 • 445 citations

New insights on mammalian phospholipase A 2 (s); comparison of arachidonoyl‐selective and ‐nonselective enzymes

1993 • 443 citations

A specific receptor antagonist for interleukin 1 prevents Escherichia coli ‐induced shock in rabbits

1991 • 435 citations

Membrane fusion

1973 • 434 citations

Infection in the pathogenesis of preterm labor.

1988 • 430 citations

Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937.

1990 • 428 citations

A new role for phospholipase A2: protection of membranes from lipid peroxidation damage

1987 • 428 citations

Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor/kinase

1986 • 421 citations

Mediators of Inflammation

1983 • 419 citations

Serum amyloid A-containing human high density lipoprotein 3. Density, size, and apolipoprotein composition.

1986 • 419 citations

The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells.

1991 • 413 citations

Induction of phospholipase A2 gene expression in human hepatoma cells by mediators of the acute phase response

1991 • 406 citations

Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis.

1975 • 393 citations

"Blastokinin": Inducer and Regulator of Blastocyst Development in the Rabbit Uterus

1967 • 388 citations

Phospholipase A2 — a mediator between proximal and distal effectors of inflammation

1991 • 384 citations

Role of secretory phospholipases A2 in the pathobiology of disease.

1986 • 382 citations

Novel method for studying mRNA phenotypes in single or small numbers of cells

1989 • 382 citations

Accumulation of Cyclooxygenase Products of Arachidonic Acid Metabolism in Gerbil Brain During Reperfusion After Bilateral Common Carotid Artery Occlusion

1980 • 367 citations

Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.

1994 • 352 citations

Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis.

1980 • 350 citations

Lysolecithin and Cell Fusion

1970 • 350 citations

Uteroglobin: A hormone-sensitive endometrial protein involved in blastocyst development

1968 • 343 citations

Evolutionary relationships and implications for the regulation of phospholipase A2 from snake venom to human secreted forms

1990 • 328 citations

Amiodarone Pulmonary Toxicity

1982 • 327 citations

Phosphatidylinositol 4,5-bisphosphate hydrolysis in human sperm stimulated with follicular fluid or progesterone is dependent upon Ca2+ influx

1989 • 318 citations

Identification of neutral active phospholipase C which hydrolyzes choline glycerophospholipids and plasmalogen selective phospholipase A2 in canine myocardium.

1985 • 315 citations

Function and Inhibition of Intracellular Calcium-independent Phospholipase A2

1997 • 306 citations

Accumulation of lysophosphoglycerides with arrhythmogenic properties in ischemic myocardium.

1978 • 302 citations

Endotoxin, tumor necrosis factor-α and interleukin 1 induce interleukin 6 production in vivo

1989 • 298 citations

Accumulation of unesterified arachidonic acid in ischemic canine myocardium. Relationship to a phosphatidylcholine deacylation-reacylation cycle and the depletion of membrane phospholipids.

1984 • 296 citations

Methylation of histidine-48 in pancreatic phospholipase A2. Role of histidine and calcium ion in the catalytic mechanism

1980 • 292 citations

Regulation of arachidonic acid metabolites in macrophages.

1980 • 283 citations

Uptake and tissue content of fatty acids in dog myocardium under normoxic and ischemic conditions.

1982 • 279 citations

Exocrine pancreatic tumours and their histological classification. A study based on 167 autopsy and 97 surgical cases

1983 • 277 citations

Mechanism of Arachidonic Acid Liberation During Ischemia in Gerbil Cerebral Cortex

1987 • 271 citations

Ca(2+)-independent cytosolic phospholipase A2 from macrophage-like P388D1 cells. Isolation and characterization.

1994 • 264 citations

Interleukin 1 activates phospholipase A2 in rabbit chondrocytes: a possible signal for IL 1 action.

1986 • 259 citations

Cloning, Chromosomal Mapping, and Expression of a Novel Human Secretory Phospholipase A2

1997 • 256 citations

Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. Two distinct pathways of the gene expression

1991 • 253 citations

Time course of changes in porcine myocardial phospholipid levels during ischemia. A reassessment of the lysolipid hypothesis.

1981 • 251 citations

Structures of Free and Inhibited Human Secretory Phospholipase A 2 from Inflammatory Exudate

1991 • 251 citations

Vasoactive properties of acetyl glyceryl ether phosphorylcholine and analogues.

1982 • 250 citations

Separation and purification of a potent bactericidal/permeability-increasing protein and a closely associated phospholipase A2 from rabbit polymorphonuclear leukocytes. Observations on their relationship.

1979 • 247 citations

Novel anti-inflammatory peptides from the region of highest similarity between uteroglobin and lipocortin I

1988 • 244 citations

A sensitive and continuous fluorometric assay for phospholipase A2 using pyrene-labeled phospholipids in the presence of serum albumin

1989 • 241 citations

Arachidonic Acid Metabolism: Implications of Biological Chemistry for Lung Function and Disease

1991 • 240 citations

Early Events in Mammalian Fertilization

1987 • 236 citations

Extracellular phospholipase A2 expression and inflammation: the relationship with associated disease states.

1993 • 236 citations

Properties and purification of an arachidonoyl-hydrolyzing phospholipase A2 from a macrophage cell line, RAW 264.7

1988 • 236 citations

The influence of phospholipase A2 and glutathione peroxidase on the elimination of membrane lipid peroxides

1983 • 235 citations

Purification and characterization of canine myocardial cytosolic phospholipase A2. A calcium-independent phospholipase with absolute f1-2 regiospecificity for diradyl glycerophospholipids.

1990 • 234 citations

Interleukin-1 alpha induces the accumulation of cytosolic phospholipase A2 and the release of prostaglandin E2 in human fibroblasts.

1992 • 230 citations

Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine.

1986 • 229 citations

MOLECULAR BASIS OF FERTILIZATION

1989 • 229 citations

Pancreatic Phospholipase A2: Isolation of the Human Gene and cDNAs from Porcine Pancreas and Human Lung

1986 • 225 citations

Regulation of Fatty Acid Utilization in Isolated Perfused Rat Hearts

1973 • 222 citations

Phospholipid metabolism by phagocytic cells. Phospholipases A2 associated with rabbit polymorphonuclear leukocyte granules

1974 • 222 citations

Multiple-Organ Failure and Sepsis Without Bacteria

1986 • 219 citations

Plasma Platelet-activating Factor Acetylhydrolase Is a Secreted Phospholipase A2 with a Catalytic Triad

1995 • 217 citations

C-reactive protein and the acute phase response.

1982 • 216 citations

Increased plasma phospholipase-A2 activity in schizophrenic patients: Reduction after neuroleptic therapy

1987 • 216 citations

Increased calcium-ion influx is a component of capacitation of spermatozoa

1978 • 214 citations

Serum amyloid A changes high density lipoprotein's cellular affinity. A clue to serum amyloid A's principal function.

1992 • 213 citations

Phospholipid alterations in canine ischemic myocardium. Temporal and topographical correlations with Tc-99m-PPi accumulation and an in vitro sarcolemmal Ca2+ permeability defect.

1981 • 213 citations

Molecular nature of phospholipases A2 involved in prostaglandin I2 synthesis in human umbilical vein endothelial cells. Possible participation of cytosolic and extracellular type II phospholipases A2.

1993 • 210 citations

Phospholipase A2 enzymes: Regulation and physiological role

1994 • 207 citations

Glucocorticoids suppress group II phospholipase A2 production by blocking mRNA synthesis and post-transcriptional expression.

1990 • 207 citations

Free Arachidonic Acid and Other Lipids in the Nervous System During Early Ischemia and After Electroshock

1976 • 204 citations

Tumour necrosis factor (cachectin) induces phospholipase A2 activity and synthesis of a phospholipase A2-activating protein in endothelial cells

1988 • 203 citations

Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells.

1988 • 203 citations

Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 Å resolution

1991 • 201 citations

Uteroglobin inhibits phospholipase A2 activity

1986 • 200 citations

Evidence for neutrophil-related acute lung injury after intestinal ischemia-reperfusion.

1989 • 199 citations

Elevated plasma phospholipase A2 levels: correlation with the hemodynamic and pulmonary changes in gram-negative septic shock.

1984 • 197 citations

Changes in the synthesis and metabolism of prostaglandins by human fetal membranes and decidua at labor

1985 • 196 citations

Prostaglandin concentrations in amniotic fluid of women with intra-amniotic infection and preterm labor

1987 • 194 citations

Serum Phospholipase A<sup>2</sup> in Inflammatory Diseases

1997 • 193 citations

Thrombin-induced phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in human platelets.

1993 • 191 citations

Increased serum phospholipase A2 activity in schizophrenia: a replication study.

1990 • 191 citations

Activation of a membrane-associated phospholipase A2 during rabbit myocardial ischemia which is highly selective for plasmalogen substrate.

1991 • 189 citations

Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear Cells.

1977 • 188 citations

Preterm labor: Stimulation of arachidonic acid metabolism in human amnion cells by bacterial products

1987 • 187 citations

Elevated plasma fibrinopeptide A and thromboxane B2 levels during cardiopulmonary bypass.

1980 • 187 citations

Effects of various lipids on the acrosome reaction and fertilizing capacity of guinea pig spermatozoa with special reference to the possible involvement of lysophospholipids in the acrosome reaction

1981 • 187 citations

Phospholipase A2 activity in sera and synovial fluids in rheumatoid arthritis and osteoarthritis. Its possible role as a proinflammatory enzyme.

1985 • 185 citations

Some studies on the metabolism of phospholipids in Golgi complex from bovine and rat liver in comparison to other subcellular fractions

1971 • 185 citations

Inhibition of pulmonary surfactant function by phospholipases

1991 • 184 citations

Activation of Ethanolamine Phospholipase A2 in Brain During Ischemia

1982 • 183 citations

Group II phospholipase A2 mRNA synthesis is stimulated by two distinct mechanisms in rat vascular smooth muscle cells

1990 • 182 citations

Amiodarone-associated phospholipidosis and fibrosis of the liver. Light, immunohistochemical, and electron microscopic studies.

1984 • 179 citations

Regulation of arachidonic acid metabolism by macrophage activation.

1982 • 176 citations

Cytokines in disease

1990 • 176 citations

Group IV Cytosolic Phospholipase A2 Binds with High Affinity and Specificity to Phosphatidylinositol 4,5-Bisphosphate Resulting in Dramatic Increases in Activity

1998 • 176 citations

Biologically active products of complement and acute lung injury in patients with the sepsis syndrome.

1984 • 175 citations

Purification of a high-molecular-mass form of phospholipase A2 from rat kidney activated at physiological calcium concentrations

1990 • 174 citations

Novel proliferative effect of phospholipase A2 in Swiss 3T3 cells via specific binding site.

1991 • 174 citations

The activation of motility in quiescent hamster sperm from the epididymis by calcium and cyclic nucleotides

1974 • 173 citations

Structure and Catalytic Mechanism of Secretory Phospholipases A2

1994 • 173 citations

Cytosolic Phospholipase A2 Is Phosphorylated in Collagen- and Thrombin-stimulated Human Platelets Independent of Protein Kinase C and Mitogen-activated Protein Kinase

1995 • 172 citations

Mechanisms Contributing to Malignant Dysrhythmias Induced by Ischemia in the Cat

1978 • 168 citations

Purification and Characterization of Extracellular Phospholipase A2 from Human Synovial Fluid in Rheumatoid Arthritis1

1989 • 166 citations

Triggering of Histamine Release from Rat Mast Cells by Divalent Antibodies against IgE-Receptors

1978 • 165 citations

Effects of phospholipase A2 inhibitors on ruthenium red-induced Ca2+ release from mitochondria.

1985 • 160 citations

Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases.

1981 • 157 citations

Circulating phospholipase A2 activity associated with sepsis and septic shock is indistinguishable from that associated with rheumatoid arthritis

1991 • 156 citations

Serum phospholipases A2 in inflammatory diseases

1993 • 155 citations

Control of arachidonic acid accumulation in bone marrow-derived macrophages by acyltransferases.

1981 • 154 citations

Analysis of the cDNA for phospholipase A2 from honeybee venom glands

1989 • 153 citations

Edema-inducing activity of phospholipase A2 purified from human synovial fluid and inhibition by aristolochic acid

1988 • 152 citations

Mepacrine blocks beta-adrenergic agonist-induced desensitization in astrocytoma cells.

1980 • 151 citations

Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion

1991 • 151 citations

Identification and purification of sheep platelet phospholipase A2 isoforms. Activation by physiologic concentrations of calcium ion.

1986 • 147 citations

Purification and Characterization of Phospholipase A2 Released from Rat Platelets

1987 • 147 citations

INTERLEUKIN-6 AND ITS RECEPTOR

2001 • 145 citations

Hormone selective lipase activation in the isolated rabbit heart

1977 • 142 citations

VALUE OF BLOOD AMYLASE ESTIMATIONS IN THE DIAGNOSIS OF PANCREATIC DISEASE

1929 • 141 citations

The purification and properties of phospholipase A from human pancreas

1962 • 140 citations

The Role of Phospholipase A in Acute Pancreatitis

1980 • 139 citations

Elevated PLA2 activity in schizophrenics and other psychiatric patients

1993 • 138 citations

A cytosolic phospholipase in human neutrophils that hydrolyzes arachidonoyl-containing phosphatidylcholine

1986 • 137 citations

Electrophysiological effects of amphiphiles on canine purkinje fibers. Implications for dysrhythmia secondary to ischemia.

1981 • 136 citations

Antigen-initiated release of platelet-activating factor (PAF-acether) from mouse bone marrow-derived mast cells sensitized with monoclonal IgE.

1983 • 136 citations

An 100‐kDa arachidonate‐mobilizing phospholipase A2 in mouse spleen and the macrophage cell line J774

1991 • 136 citations

Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate.

1990 • 134 citations

Structural and functional properties of a phospholipase A2 purified from an inflammatory exudate

1986 • 134 citations

Kinetic properties of a high molecular mass arachidonoyl-hydrolyzing phospholipase A2 that exhibits lysophospholipase activity

1991 • 133 citations

Measurement of lecithinase A in serum and other body fluids.

1961 • 132 citations

Inhibition of microsomal lipid peroxidation by glutathione and glutathione transferases B and AA. Role of endogenous phospholipase A2

1984 • 128 citations

Purification and characterization of a membrane-associated phospholipase A2 from rat spleen. Its comparison with a cytosolic phospholipase A2 S-1.

1988 • 128 citations

Human extracellular recombinant phospholipase A2 induces an inflammatory response in rabbit joints.

1991 • 127 citations

Differential Activation of Cytosolic Phospholipase A2 (cPLA2) by Thrombin and Thrombin Receptor Agonist Peptide in Human Platelets. EVIDENCE FOR ACTIVATION OF cPLA2 INDEPENDENT OF THE MITOGEN-ACTIVATED PROTEIN KINASES ERK1/2

1995 • 126 citations

Polyphosphoinositide breakdown and subsequent exocytosis in the Ca2+/ionophore-induced acrosome reaction of mammalian spermatozoa

1989 • 125 citations

The rapid and reversible activation of a calcium-independent plasmalogen-selective phospholipase A2 during myocardial ischemia.

1991 • 125 citations

THE SYNOVIAL PROSTAGLANDIN SYSTEM IN CHRONIC INFLAMMATORY ARTHRITIS: DIFFERENTIAL EFFECTS OF STEROIDAL AND NONSTEROIDAL ANTI‐INFLAMMATORY DRUGS

1981 • 124 citations

Pathogenesis of hypotension in septic shock

1988 • 124 citations

Translocation of phospholipase A2 from cytosol to membranes in rat brain induced by calcium ions

1990 • 124 citations

Mammalian calcium-independent phospholipase A2

1995 • 123 citations

Suppression of Epididymal Sperm Antigenicity in the Rabbit by Uteroglobin and Transglutaminase in Vitro

1983 • 123 citations

Bacterial lipopolysaccharide priming of P388D1 macrophage-like cells for enhanced arachidonic acid metabolism. Platelet-activating factor receptor activation and regulation of phospholipase A2.

1990 • 122 citations

The Possible Role of Phospholipase a in the Pathogenesis of Acute Pancreatitis

1969 • 121 citations

PROSTAGLANDIN PRODUCTION BY INTRA-UTERINE TISSUES FROM PERIPARTURIENT SHEEP: USE OF A SUPERFUSION TECHNIQUE

1978 • 120 citations

Classification of phospholipases A2 according to sequence. Evolutionary and pharmacological implications

1983 • 119 citations

A phospholipase A2 in the supernatant fraction of rat spleen. Its similarity to rat pancreatic phospholipase A2.

1988 • 118 citations

Lysocardiolipin formation and reacylation in isolated rat liver mitochondria

1990 • 118 citations

[Identification and characterization of two phospholipase A2 activities in resident mouse peritoneal macrophages.]

1981 • 118 citations

Group II phospholipase A2 is increased in peritoneal and pleural effusions in patients with various types of cancer

1997 • 116 citations

The Primary Structure of Bovine Pancreatic Phospholipase A2

1978 • 116 citations

Purification and characterization of human platelet phospholipase A2 which preferentially hydrolyzes an arachidonoyl residue

1991 • 115 citations

Suppressive effect of seminal plasma on lymphocyte activation

1975 • 114 citations

Angiotensin II stimulates phospholipases C and A2 in cultured rat mesangial cells

1987 • 114 citations

Purification and Characterization of Extracellular Phospholipase A2 from Peritoneal Cavity of Caseinate-Treated Rat1

1987 • 114 citations

Solubilization, purification, and characterization of a membrane-bound phospholipase A2 from the P388D1 macrophage-like cell line.

1988 • 114 citations

Liver Injury Is a Reversible Neutrophil-Mediated Event Following Gut Ischemia

1992 • 114 citations

[1] Assay strategies and methods for phospholipases

1991 • 113 citations

Studies on phospholipase A and its zymogen from porcine pancreas

1970 • 113 citations

Tumor necrosis factor alpha: a multifaceted peptide hormone.

1989 • 111 citations

Conformational properties of phospholipases A2

1983 • 111 citations

Characterization of extracellular phospholipase A2 in rheumatoid synovial fluid

1985 • 110 citations

Endotoxin stimulates prostaglandin E2 production by human amnion.

1988 • 109 citations

How a Nerve Fiber Repairs Its Cut End: Involvement of Phospholipase A 2

1983 • 109 citations

Identification of phospholipase A1 and A2 in the soluble fraction of rat liver lysosomes

1971 • 108 citations

Immunoaffinity purification, partial sequence, and subcellular localization of rat liver phospholipase A2

1989 • 107 citations

Anionic phospholipids stimulate an arachidonoyl-hydrolyzing phospholipase A2 from macrophages and reduce the calcium requirement for activity

1990 • 107 citations

Inhibition Studies on the Membrane-associated Phospholipase A2 in vitro and Prostaglandin E2 Production in vivo of the Macrophage-like P388D1 Cell

1989 • 107 citations

Sperm Motility within the Mammalian Epididymis: Species Variation and Correlation with Free Calcium Levels in Epididymal Plasma

1978 • 107 citations

The proinflammatory effect of intra-articular injection of soluble human and venom phospholipase A2.

1989 • 107 citations

Clara cell 10 kDa protein (CC10): Comparison of structure and function to uterogloblin

1990 • 106 citations

Increased expression of membrane-associated phospholipase A2 shows malignant potential of human breast cancer cells

1993 • 106 citations

Aetiology and pathogenesis of pancreatitis. (Current concepts).

1970 • 105 citations

Serum Phospholipase A2in Human Acute Pancreatitis

1980 • 105 citations

Role of Uteroglobin and Transglutaminase in Masking the Antigenicity of Implanting Rabbit Embryos*

1982 • 105 citations

Origin of the arachidonic acid released post-mortem in rat forebrain

1979 • 103 citations

Purification and characterization of rabbit platelet cytosolic phospholipase A2

1991 • 103 citations

Presence of pancreatic-type phospholipase A2 mRNA in rat gastric mucosa and lung

1989 • 102 citations

Endogenous suppression of neutral-active and calcium-dependent phospholipase A2 in human polymorphonuclear leukocytes

1986 • 102 citations

The role of calcium and Ca2+-ATPase in maintaining motility in ram spermatozoa.

1985 • 101 citations

Acute Lung Injury Induced by Phospholipase A2: Structural and Functional Changes

1991 • 100 citations

Tumor necrosis factors alpha and beta differ in their capacities to generate interleukin 1 release from human endothelial cells.

1987 • 99 citations

The primary structure of phospholipase A2 from porcine pancreas A reinvestigation

1977 • 98 citations

Amino-acid and cDNA nucleotide sequences of human Clara cell 10 kDa protein

1988 • 98 citations

ATP-dependent regulation of rabbit myocardial cytosolic calcium-independent phospholipase A2

1991 • 97 citations

Interleukin-1 alpha stimulates prostaglandin biosynthesis in serum-activated mesangial cells by induction of a non-pancreatic (type II) phospholipase A2

1991 • 96 citations

cDNA cloning and sequence determination of rat membrane-associated phospholipase A2

1989 • 96 citations

A review on methods of phospholipase a determination

1979 • 95 citations

Immunochemical Detection of Group I and Group II Phospholipases A2 in Human Serum

1992 • 95 citations

Eicosanoid generation from antigen‐primed mast cells by extracellular mammalian 14‐kDa group II phospholipase A2

1991 • 95 citations

Characterization and activity of phospholipase A2 in normal human epidermis and in lesion-free epidermis of patients with psoriasis or eczema

1985 • 93 citations

Esterification of an endogenously synthesized lipoxygenase product into granulocyte cellular lipids

1981 • 93 citations

Mechanism of arachidonic acid release in human polymorphonuclear leukocytes

1983 • 93 citations

Control of prostanoid synthesis: Role of reincorporation of released precursor fatty acids

1986 • 92 citations

Phospholipid hydrolysis by phospholipases A1 and A2 in plasma membranes and microsomes of rat liver

1973 • 92 citations

Dog and Rat Pancreatic Phospholipases A2: Complete Amino Acid Sequences Deduced from Complementary DNAs

1986 • 92 citations

Lysophosphatidylcholine metabolism in the rabbit heart. Characterization of metabolic pathways and partial purification of myocardial lysophospholipase-transacylase.

1982 • 92 citations

Coenzyme A-mediated arachidonic acid transacylation in human platelets.

1984 • 91 citations

Bacterial endotoxin and current concepts in the diagnosis and treatment of endotoxaemia

1990 • 91 citations

Phospholipase A2 activity in resting and activated human neutrophils. Substrate specificity, pH dependence, and subcellular localization.

1988 • 90 citations

Distribution of pancreatic (group I) and synovial-type (group II) phospholipases A2 in human tissues

1993 • 90 citations

Radioimmunoassay of human plasma trypsin

1976 • 90 citations

A Rapid and Sensitive Turbidimetric Method for Serum Lipase Based Upon Differences Between the Lipases of Normal and Pancreatitis Serum

1963 • 90 citations

The Calcium-dependent Association and Functional Coupling of Calmodulin with Myocardial Phospholipase A2

1996 • 89 citations

Is prostacyclin the major pro-inflammatory prostanoid in joint fluid?

1980 • 89 citations

Pancreatic elastase in human serum. Determination by radioimmunoassay.

1977 • 88 citations

The Primary Structure of Rat Platelet Phospholipase A21

1988 • 88 citations

Interleukin‐1 activates phospholipase a2 IN HUMAN SYNOVIAL CELLS

1988 • 87 citations

Serum phospholipase A2 correlates with disease activity in rheumatoid arthritis.

1988 • 87 citations

Purification of Rabbit Platelet Secretory Phospholipase A2 and Its Characteristics1

1989 • 87 citations

Increased synthesis of high-molecular-weight cPLA2 mediates early UV-induced PGE2 in human skin

1996 • 87 citations

The complete primary structure of phospholipase A2 from human pancreas

1983 • 87 citations

Selective Release of Phospholipase A2 and Lysophosphatidylserine- Specific Lysophospholipase from Rat Platelets1

1987 • 86 citations

Phospholipase A activity of rat-liver mitochondria

1965 • 86 citations

Prostaglandin E2 production is synergistically increased in cultured human glomerular mesangial cells by combinations of IL-1 and tumor necrosis factor-alpha 1.

1989 • 86 citations

Myocardial phospholipase a of microsomal and mitochondrial fractions

1971 • 86 citations

Involvement of circulating phospholipase A2 in the pathogenesis of the hemodynamic changes in endotoxin shock

1983 • 86 citations

Purification of a Soluble Phospholipase A2 from Synovial Fluid in Rheumatoid Arthritis1

1986 • 86 citations

Isolation and characterization of a phospholipase A2 from an inflammatory exudate

1978 • 85 citations

Effects of recombinant interleukin-1 beta on phospholipase A2 activity, phospholipase A2 mRNA levels, and eicosanoid formation in rabbit chondrocytes

1989 • 85 citations

Interleukin-1β stimulates phospholipase A2 mRNA synthesis in rabbit articular chondrocytes

1989 • 84 citations

Rabbit myocardial cytosolic lysophospholipase. Purification, characterization, and competitive inhibition by L-palmitoyl carnitine.

1983 • 84 citations

Phospholipase A2 activation and subsequent exocytosis in the Ca2+/ionophore-induced acrosome reaction of ram spermatozoa

1993 • 84 citations

Phospholipase A2 inhibition prevents mucosal damage associated with small intestinal ischaemia in rats.

1988 • 83 citations

Evidence for a catalytic role of phospholipase A in phorbol diester- and zymosan-induced mobilization of arachidonic acid in mouse peritoneal macrophages

1986 • 82 citations

Extracellular phospholipase A2 mediates inflammatory hyperaemia

1981 • 82 citations

Time-resolved fluoroimmunoassay of human pancreatic phospholipase A2.

1983 • 81 citations

Endotoxaemia and complement activation in acute pancreatitis in man.

1982 • 81 citations

Characterization of blood mononuclear cells of rheumatoid arthritis patients

1982 • 81 citations

A subpopulation of cultured human promyelocytic leukemia cells (HL-60) displays the formyl peptide chemotactic receptor.

1980 • 81 citations

Tumour‐necrosis‐factor‐mediated cytotoxicity is correlated with phospholipase‐A2 activity, but not with arachidonic acid release per se

1991 • 80 citations

Evidence for two mechanisms by which tumor necrosis factor kills cells

1989 • 80 citations

Pancreatic and synovial type phospholipases A2 in serum samples from patients with severe acute pancreatitis.

1993 • 79 citations

Phospholipase A2 and arthritis

1993 • 79 citations

Evidence for the activation of phospholipases during acrosome reaction of human sperm elicited by calcium ionophore A23187

1987 • 79 citations

Effects of antimalarial drugs on phospholipase A and lysophospholipase activities in plasma membrane, mitochondrial, microsomal and cytosolic subcellular fractions of rat liver

1985 • 79 citations

Phospholipase A2 Regulates Critical Inflammatory Mediators of Multiple Organ Failure

1994 • 78 citations

Secretory phospholipase A2 as an index of disease activity in rheumatoid arthritis. Prospective double blind study of 212 patients.

1996 • 78 citations

Lysolecithin: A factor in the pathogenesis of gastric ulceration?

1974 • 78 citations

Interleukin-1 beta- and forskolin-induced synthesis and secretion of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by transforming growth factor-beta 2.

1992 • 78 citations

Hydrolases of pulmonary lysosomes and lamellar bodies.

1982 • 77 citations

Purification and Characterization of Human Pancreatic Phospholipase A2 and Development of a Radioimmunoassay1

1983 • 77 citations

Purification of rat liver mitochondrial phospholipase A2

1982 • 76 citations

Isolation and Properties of Prophosholipase A2 from Ox and Sheep Pancreas

1975 • 76 citations

Rabbit myocardial lysophospholipase-transacylase. Purification, characterization, and inhibition by endogenous cardiac amphiphiles.

1983 • 75 citations

Phospholipases in biology and medicine

1990 • 75 citations

MEASUREMENT OF HUMAN PHOSPHOLIPASE A IN ARTHRITIS PLASMA USING A NEWLY DEVELOPED SANDWICH ELISA

1992 • 74 citations

The primary structure of a membrane-associated phospholipase A2 from human spleen

1989 • 74 citations

Gene expression of group II phospholipase A2 in intestine in ulcerative colitis.

1997 • 74 citations

Neutrophil function and lipid peroxidation in a rat model of multiple organ failure

1989 • 73 citations

Elevation of serum group II phospholipase A2 levels in patients with advanced cancer

1994 • 73 citations

Total chemical synthesis of enzymatically active human type II secretory phospholipase A 2

1997 • 73 citations

Increased prostacyclin and thromboxane production in man during cardiopulmonary bypass

1981 • 73 citations

The level of phospholipase A2 activity is raised in the uninvolved epidermis of psoriasis

1983 • 72 citations

EARLY AND DISCRETE CHANGES IN PERMEABILITY OF ESCHERICHIA COLI AND CERTAIN OTHER GRAM-NEGATIVE BACTERIA DURING KILLING BY GRANULOCYTES

1974 • 72 citations

Primary Structures of Canine Pancreatic Lipase and Phospholipase A2 Messenger RNAs

1986 • 71 citations

Phospholipase A2in Acute Pancreatitis

1988 • 70 citations

Secretory non-pancreatic group II phospholipase A2: role in physiologic and inflammatory processes.

1993 • 70 citations

The specific association of a phosphofructokinase isoform with myocardial calcium-independent phospholipase A2. Implications for the coordinated regulation of phospholipolysis and glycolysis

1993 • 70 citations

A continuous fluorescence displacement assay for the measurement of phospholipase A2 and other lipases that release long-chain fatty acids

1990 • 70 citations

The appearance of phospholipase and cyclo-oxygenase activities in the human promyelocytic leukemia cell line HL60 during dimethyl sulfoxide-induced differentiation

1981 • 69 citations

Inflammatory Effect of Intradermal Administration of Soluble Phospholipase A2 in Rabbits

1986 • 68 citations

Detection of Three Distinct Phospholipases A2 in Cultured Mast Cells1

1992 • 68 citations

Role of phospholipase A2 and oxygenated free radicals in mucosal damage after small intestinal ischemia and reperfusion

1989 • 67 citations

Phospholipase A activity associated with membranes of human polymorphonuclear leucocytes

1977 • 67 citations

Increased Concentrations of Synovial-Type Phospholipase A<sub>2</sub> in Serum and Pulmonary and Renal Complications in Acute Pancreatitis

1992 • 66 citations

Aspirin inhibits phospholipase C

1986 • 66 citations

The role of arachidonic acid metabolites in preeclampsia.

1986 • 66 citations

Phospholipase activities of the P388D1 macrophage-like cell line

1985 • 65 citations

Surfactant phospholipids and lavage phospholipase A2 in experimental Pneumocystis carinii pneumonia.

1986 • 65 citations

Group II Phospholipase A2 in Sera of Febrile Patients with Microbiologically or Clinically Documented Infections

1993 • 64 citations

What Is the Best Biochemical Test to Diagnose Acute Pancreatitis? A Prospective Clinical Study

1996 • 64 citations

Calcium independent phospholipase A 2 activity in rat lung supernatant.

1972 • 63 citations

Phospholipase A2 from human synovial fluid: Purification and structural homology to the placental enzyme

1988 • 63 citations

Calcium independent phospholipase A2 activity in rat lung supernatant

1972 • 63 citations

Continuous fluorometric assay of phospholipase A2 with pyrene-labeled lecithin as a substrate

1981 • 63 citations

Evidence that interleukin‐1 induction of synovial cell plasminogen activator is mediated via prostaglandin E2 and cAMP

1986 • 62 citations

Platelet-activating factor and phospholipase A2 in patients with septic shock and trauma

1994 • 62 citations

Phospholipid composition, phospholipase A2 and sphingomyelinase activities in rat liver nuclear membrane and matrix

1995 • 62 citations

Identification of a calcium-independent phospholipase A2 in rat lung cytosol and differentiation from acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF-acether)

1986 • 61 citations

Amino Acid Composition and NH2-Terminal Amino Acid Sequence of Human Phospholipase A2 Purified from Rheumatoid Synovial Fluid1

1988 • 61 citations

Panc reatic Enzymes in Chronic Renal Failure

1987 • 59 citations

Serum phospholipase A2 enzyme activity and immunoreactivity in a prospective analysis of patients with septic shock

1992 • 59 citations

Multiple Forms of Phospholipase A2 in Arthritic Synovial Fluid

1989 • 59 citations

Glucose increases the synthesis of lipoxygenase-mediated metabolites of arachidonic acid in intact rat islets.

1985 • 59 citations

Ozone interactions with lung tissue

1976 • 59 citations

Amylase, lipase, pancreatic isoamylase, and phospholipase A in diagnosis of acute pancreatitis

1995 • 59 citations

Increased phospholipase A2 and decreased lysophospholipase activity in the small intestinal mucosa after ischaemia and revascularisation.

1987 • 58 citations

Immunoreactive phospholipase A2 in serum in acute pancreatitis and pancreatic cancer.

1985 • 58 citations

Fluorometric assay for phospholipase A2 in serum.

1985 • 58 citations

Improved Method for the Determination of Phospholipase A2 Catalytic Activity Concentration in Human Serum and Ascites

1987 • 58 citations

Isolation and properties of prophospholipase A2 and phospholipase A2 from horse pancreas and horse pancreatic juice

1977 • 57 citations

Phagocytosis of bacteria and phospholipid degradation

1988 • 57 citations

Effects of various factors on prostaglandin synthesis by the guinea-pig uterus

1987 • 57 citations

Expression of group-II phospholipase A2 in malignant and non-malignant human gastric mucosa

1993 • 56 citations

Serum Phospholipase A2 in Patients with Multiple Organ Failure

1996 • 56 citations

Biologically Active Calmodulin Levels Are Elevated in Both Involved and Uninvolved Epidermis in Psoriasis

1984 • 56 citations

Stimulation of arachidonic acid release by guanine nucleotide in saponin-permeabilized neutrophils: Evidence for involvement of GTP-binding protein in phospholipase A2 activation

1988 • 56 citations

Characterization of phospholipase A2 from human nasal lavage.

1994 • 56 citations

The molecular species composition of diacyl-, alkylacyl- and alkenylacylglycerophospholipids in rabbit alveolar macrophages. High amounts of 1-O-hexadecyl-2-arachidonyl molecular species in alkylacylglycerophosphocholine

1985 • 56 citations

Identification and characterization of a phospholipase C activity in resident mouse peritoneal macrophages. Inhibition of the enzyme by phenothiazines

1981 • 56 citations

Diagnostic and prognostic utility of phospholipase A activity in patients with acute pancreatitis: comparison with amylase and lipase

1991 • 55 citations

Exacerbation of rat adjuvant arthritis by intradermal injection of purified mammalian 14‐kDa group II phospholipase A2

1990 • 55 citations

Characteristics of mononuclear cell populations in chronically inflamed synovial membranes

1977 • 55 citations

Raised serum activity of phospholipase A2 immunochemically related to group II enzyme in inflammatory bowel disease: its correlation with disease activity of Crohn's disease and ulcerative colitis.

1992 • 55 citations

Development of a Radioimmunoassay for Human Group-II Phospholipase A2 and Demonstration of Postoperative Elevation

1991 • 55 citations

Regulation of Lysophospholipase Activity of the 85-kDa Phospholipase A2 and Activation in Mouse Peritoneal Macrophages

1995 • 55 citations

A dimeric form of lipocortin-1 in human placenta

1989 • 54 citations

Type 1 prophospholipase A2 propeptide in acute lung injury

1994 • 54 citations

Phospholipase A2 stimulation during cell secretion in rat basophilic leukemia cells.

1986 • 54 citations

Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture

1983 • 54 citations

Effect of pancreatic type phospholipase A2 on isolated porcine cerebral arteries via its specific binding sites

1992 • 54 citations

Cyclic AMP mimics, but does not mediate, interleukin-1- and tumour-necrosis-factor-stimulated phospholipase A2 secretion from rat renal mesangial cells

1991 • 53 citations

The release of phospholipase A2 from aggregated platelets and stimulated macrophages of sheep

1980 • 53 citations

Immunoelectron microscopic localization of calmodulin and phospholipase A2 in spermatozoa. I.

1986 • 53 citations

Crosslinking of uteroglobin by transglutaminase

1984 • 52 citations

Metabolism of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human promyelocytic leukemic HL60 cells. Stimulated expression of phospholipase A2 and acetyltransferase requires differentiation.

1986 • 52 citations

Prostaglandins and cellular calcium transport in the pregnant human uterus

1973 • 52 citations

Cytokine mediators of septic infections in the normal and granulocytopenic host

1993 • 51 citations

Hepatic involvement in pancreatitis-induced lung damage

1996 • 51 citations

The Relationship Between Pancreatic Enzyme Release and Activation and the Acute-Phase Protein Response in Patients with Acute Pancreatitis

1995 • 50 citations

Phospholipase A2 activity in the plasma membrane of human polymorphonuclear leukocytes

1981 • 50 citations

Activation of rabbit articular chondrocytes by recombinant human cytokines.

1987 • 50 citations

Regulation of natural killer cell cytotoxicity by prostaglandin E in the peripheral blood and cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases part 1. Association between amount of prostaglandin produced, natural killer, and endogenous interferon☆

1983 • 49 citations

Synovial type (group II) phospholipase A2 in cartilage.

1993 • 49 citations

Possible mechanism of success of an allotransplantation in nature: Mammalian pregnancy

1980 • 49 citations

Rat Pancreatic Phospholipase A2: Purification, Characterization, and N-Terminal Amino Acid Sequence1

1984 • 49 citations

Ether-Linked Lysophospholipids Initiate Insulin Secretion: Lysophospholipids May Mediate Effects of Phospholipase A2 Activation on Hormone Release

1986 • 48 citations

Pathophysiological role of secretory type I and II phospholipase A2 in acute pancreatitis: an experimental study in rats.

1997 • 48 citations

Phospholipase A2 activation in chemotactic peptide-stimulated HL60 granulocytes: Synergism between diacylglycerol and CA2+ in a protein kinase C-independent mechanism

1987 • 48 citations

Purification and characterization of human pancreatic phospholipase A2.

1983 • 48 citations

Immunohistochemical localization of group II phospholipase A2 in human pancreatic carcinomas

1993 • 48 citations

Is phospholipase A2 a “glucose sensor” responsible for the phasic pattern of insulin release?

1984 • 48 citations

Effects of CDP-choline on phospholipase A2 and cholinephosphotransferase activities following a cryogenic brain injury in the rabbit

1987 • 47 citations

Initiation of human parturition. IV. Demonstration of phospholipase A2 in the lysosomes of human fetal membranes.

1976 • 47 citations

Tumor necrosis factor and interleukin 1 activate phospholipase in rat chondrocytes

1988 • 47 citations

RELEASE OF LYSOSOMAL ACID PHOSPHATASE INTO THE CYTOPLASM OF DECIDUAL CELLS BEFORE THE ONSET OF LABOUR IN HUMANS

1975 • 47 citations

Plasma concentrations of type II phospholipase A2, cytokines and eicosanoids in patients with burns

1995 • 47 citations

Release of phospholipase A2 activity from rabbit peritoneal neutrophils by f-Met-Leu-Phe.

1983 • 46 citations

Biochemical signal transmitted by Fc gamma receptors: phospholipase A2 activity of Fc gamma 2b receptor of murine macrophage cell line P388D1.

1982 • 46 citations

Phospholipase A<sub>2</sub> Activity in Prostasomes from Human Seminal Plasma

1987 • 46 citations

Intracellular localization of group II phospholipase A2 in rat vascular smooth muscle cells and its possible relationship to eicosanoid formation

1991 • 46 citations

Interleukin 1 stimulation of synovial cell plasminogen activator production.

1986 • 46 citations

Extracellular phospholipase A2: causative agent in circulatory collapse of septic shock?

1988 • 46 citations

Studies on a new variant of the Hermansky‐Pudlak syndrome: Qualitative, ultrastructural, and functional abnormalities of the platelet‐dense bodies associated with a phospholipase a defect

1978 • 46 citations

Accumulation of lysophosphatidylinositol in RAW 264.7 macrophage tumor cells stimulated by lipid A precursors.

1987 • 45 citations

Enhanced phospholipase activity in peripheral blood monocytes from patients with rheumatoid arthritis

1986 • 45 citations

A zymogen of phospholipase A in human pancreatic juice

1971 • 44 citations

Phospholipase A2 activity of lysosomal origin secreted by polymorphonuclear leucocytes during phagocytosis or on treatment with calcium

1981 • 44 citations

Purification and properties of acyl-CoA: 1-acyl-sn-glycero-3-phosphocholine-O-acyltransferase from bovine brain microsomes

1986 • 44 citations

Acylation of 1-alkenyl-glycerophosphocholine and 1-acyl-glycerophosphocholine in guinea pig heart

1986 • 44 citations

Phospholipase A 2 modulation by calmodulin, prostaglandins and cyclic nucleotides

1983 • 44 citations

Phospholipase A2 Activity in Serum of Neuroleptic-Naive Psychiatric Inpatients

1993 • 44 citations

Pancreatic enzymes in patients with end-stage renal disease maintained on hemodialysis.

1988 • 44 citations

The involvement of extracellular calcium in the formation of 5‐lipoxygenase metabolites by human polymorphonuclear leukocytes

1991 • 44 citations

Release of phospholipase A2 activity from rat vascular smooth muscle cells mediated by cAMP

1989 • 43 citations

Purification and characterization of a uterine phospholipase inhibitor that loses activity after labor onset in women

1989 • 43 citations

Heparin-enhanced plasma phospholipase A2 activity and prostacyclin synthesis in patients undergoing cardiac surgery.

1995 • 42 citations

Role of Phospholipids in Coupling of Adenosine and Dopamine Receptors to Striatal Adenylate Cyclase

1981 • 42 citations

Stimulus-specific induction of phospholipid and arachidonic acid metabolism in human neutrophils

1987 • 42 citations

Acute gastric mucosal ulcerogenesis is dependent on the concentration of bile salt.

1976 • 41 citations

Effect of lysolecithin on gastric mucosal structure and potential difference.

1977 • 41 citations

PDGF suppresses the activation of group II phospholipase A2 gene expression by interleukin I and forskolin in mesangial cells

1991 • 41 citations

Partial Purification and Properties of Phospholipase A2 from Rat Liver Mitochondria1

1983 • 41 citations

Isolation and properties of prophospholipase A2 from human pancreatic juice

1981 • 40 citations

Neutrophil association and degradation of normal and acute-phase high-density lipoprotein 3

1987 • 40 citations

Phospholipase A2 from plasma of patients with septic shock is associated with high-density lipoproteins and C3 anaphylatoxin: some implications for its functional role

1995 • 40 citations

Systemic phospholipase A2 and cachectin levels in adult respiratory distress syndrome and multiple-organ failure

1992 • 40 citations

Isolation of purified brush-border membranes from rat jejunum containing a Ca2+-independent phospholipase A2 activity

1987 • 40 citations

Phospholipases: Old Enzymes With New Meaning

1990 • 39 citations

Purification of rabbit myocardial cytosolic acyl-CoA hydrolase, identity with lysophospholipase, and modulation of enzymic activity by endogenous cardiac amphiphiles

1983 • 39 citations

Immunoreactive pancreatic colipase, lipase and phospholipase A2 in human plasma and urine from healthy individuals

1984 • 39 citations

Purification and Characterization of Membrane-Bound Phospholipase A2 from Rat Platelets1

1988 • 39 citations

Phospholipase A2-induced rat mast cell secretion. Role of arachidonic acid metabolites.

1982 • 39 citations

Hyperphospholipasemia A2 in human volunteers challenged with intravenous endotoxin

1992 • 38 citations

Purification and properties of phospholipase A2 from human seminal plasma

1985 • 38 citations

Differential actions of diacyl- and alkylacylglycerols in priming phospholipase A2, 5-lipoxygenase and acetyltransferase activation in human neutrophils

1991 • 37 citations

Mechanism of human lymphotoxin and tumor necrosis factor induced destruction of cells in vitro: Phospholipase activation and deacylation of specific‐membrane phospholipids

1990 • 37 citations

Modulation of lipolytic activity in isolated canine cardiac sarcolemma by isoproterenol and propranolol

1979 • 37 citations

In vivo release and clearance of rat platelet phospholipase A2

1989 • 37 citations

Acylchain Specificity and Kinetic Properties of Phospholipase A1 and A2 of Bone Marrow-Derived Macrophages

1985 • 37 citations

A correlation between clinical pancreatitis and isoenzyme patterns of amylase

1983 • 37 citations

Rat liver mitochondrial phospholipase A2 is an endotoxin-stimulated membrane-associated enzyme of Kupffer cells which is released during liver perfusion

1993 • 36 citations

Solubilization and assay of phospholipase A2 activity from rat jejunal brush-border membranes

1988 • 36 citations

Epidermal phospholipase A2 activity is raised in the uninvolved skin of psoriasis

2006 • 36 citations

Characterization of phospholipase a from pulmonary secretions of patients with alveolar proteinosis

1977 • 36 citations

Studies on Prophospholipase A2 and Its Enzyme from Human Pancreatic Juice

1982 • 36 citations

Transforming growth factor β2 differentially modulates interleukin-1 β- and tumour-necrosis-factor-α-stimulated phospholipase A2 and prostaglandin E2 synthesis in rat renal mesangial cells

1990 • 36 citations

Secretion of biologically active porcine prophospholipase A2 by Saccharomyces cerevisiae

1987 • 35 citations

Initiation of human parturition

1976 • 35 citations

Serum phospholipase A2 in intensive care patients with peritonitis, multiple injury, and necrotizing pancreatitis

1989 • 35 citations

In vitro studies in reproductive immunology — 2 demonstration of the inhibitory effect of male genital tract constituents on PHA-stimulated mitogenesis and E-rosette formation of human lymphocytes

1979 • 35 citations

Extracellular Phospholipase A2 Activity in Peritoneal Cavity of Casein-Treated Rats1

1986 • 34 citations

Oxygen-induced changes in pulmonary phospholipids in the rat

1975 • 34 citations

Rate of prostaglandin synthesis is not controlled by phospholipase A activity but by reincorporation of released fatty acids into phospholipids

1984 • 34 citations

Reversibility of ethanolamine and choline phosphotransferases (EC 2.7.8.1 and EC 2.7.8.2) in rat brain microsomes with labelled alkylacylglycerols

1977 • 34 citations

Recombinant secreted nonpancreatic phospholipase A2 induces a synovitis-like inflammation in the rat air pouch.

1994 • 34 citations

Ca2+‐induced reversible translocation of phospholipase A2 between the cytosol and the membrane fraction of rat liver macrophages

1991 • 33 citations

Activity of Phospholipase A2 in the Inner Membrane of Rat-Liver Mitochondria

1981 • 33 citations

Enzymatic activity and immunoreactivity of extracellular phospholipase A2 in inflammatory synovial fluids

1992 • 33 citations

A pancreatic-type phospholipase A2 in rat gastric mucosa

1988 • 33 citations

Phospholipase A2 gene expression and activity in histologically normal ileal mucosa and in Crohn's ileitis.

1995 • 33 citations

Immunoreactive pancreatic phospholipase A2 and catalytically active phospholipases A2 in serum from patients with acute pancreatitis.

1988 • 33 citations

Phospholipase A2 activating protein and idiopathic inflammatory bowel disease.

1996 • 32 citations

Structure and Properties of a Secretable Phospholipase A2 from Human Platelets

1990 • 32 citations

The role of phospholipases from inflammatory macrophages in demyelination

1986 • 32 citations

Arachidonic acid turnover in response to lipopolysaccharide and opsonized zymosan in human monocyte-derived macrophages

1986 • 32 citations

Phospholipase A2 assay using an intramolecularly quenched pyrene-labeled phospholipid analog as a substrate

1988 • 32 citations

Expression of a Uteroglobin-Like Protein in Human Prostate

1988 • 32 citations

Hormonally Regulated Mammalian Gene Expression: Steady-State Level and Nucleotide Sequence of Rabbit Uteroglobin mRNA

1981 • 31 citations

SERUM IMMUNOREACTIVE ANODAL TRYPSINOGEN AND URINARY AMYLASE AS BIOCHEMICAL MARKERS FOR REJECTION OF CLINICAL WHOLE-ORGAN PANCREAS ALLOGRAFTS HAVING EXOCRINE DRAINAGE INTO THE URINARY BLADDER

1990 • 31 citations

Gestational tissue phospholipase A2 messenger RNA content and the onset of spontaneous labour in the human

1990 • 31 citations

Induction of circulating group II phospholipase A2 expression in adults with malaria

1992 • 31 citations

Phospholipase A2 is a Major Component of the Salt‐Extractable Pool of Matrix Proteins in Adult Human Articular Cartilage

1991 • 31 citations

Purification and characterisation of phospholipase A2 from human epidermis

1991 • 31 citations

Role of phospholipase A in multiorgan failure with special reference to ARDS and acute renal failure (ARF)

1989 • 31 citations

Detection of 14-kDa group II phospholipase A2 in human seminal plasma

1991 • 31 citations

Serum phospholipase A2 and pulmonary changes in acute fulminant pancreatitis

1982 • 31 citations

Phospholipases, Enzymes That Share a Substrate Class

1990 • 30 citations

Enhanced Phospholipase A2 and C Activities of Peripheral Blood Polymorphonuclear Leukocytes From Patients With Rheumatoid Arthritis

1985 • 30 citations

Lipids and surface tension of extracts of normal and oxygen-treated guinea pig lungs

1964 • 30 citations

Sepsis Indicators in Acute Pancreatitis

1987 • 30 citations

Effect of Phospholipase Digestion and Lysophosphatidylcholine on Dopamine Receptor Binding

1984 • 29 citations

Purification of a Novel Phospholipase A2 from Bovine Seminal Plasma

1997 • 29 citations

Human group II phospholipase A2

1991 • 29 citations

Group II phospholipase A2 in serum in critically ill surgical patients

1994 • 29 citations

Type 1-prophospholipase A2 propeptide immunoreactivity is released from activated Granulocytes

1995 • 29 citations

Prognostic value of serum phospholipase a in the multitraumatized patient

1989 • 29 citations

Postoperative elevations of serum interleukin 6 and group II phospholipase A2: group II phospholipase A2 in serum is an acute phase reactant.

1992 • 28 citations

Increased biliary group II phospholipase A2 and altered gallbladder bile in patients with multiple cholesterol stones

1997 • 28 citations

Group II Phospholipase A2 in Invasive Gastric Cancer Cell Line Is Induced by Interleukin 6

1994 • 28 citations

The Synthesis, Catabolism, and Pathophysiological Role of Platelet-Activating Factor

1989 • 28 citations

Role of phospholipase in the genesis of doxorubicin-induced cardiomyopathy in rats.

1987 • 28 citations

Bile acid and lysolecithin concentrations in the stomach of patients with gastric ulcer: Before operation and after treatment by highly selective vagotomy, Billroth I partial gastrectomy and truncal vagotomy and pyloroplasty

1983 • 28 citations

Generation of Arachidonic Acid and Diacylglycerol Second Messengers from Polyphosphoinositides in Ischemic Fetal Brain

1992 • 27 citations

Localization and partial purification of a neutral-active phospholipase A2 from BCG-induced rabbit alveolar macrophages

1981 • 27 citations

The effects of ischaemia, lysophosphatidylcholine and palmitoylcarnitine on rat heart phospholipase A2 activity

1987 • 27 citations

Identification of a uteroglobin-like antigen in human uterine washings

1986 • 27 citations

Subcellular distribution, molecular dynamics and catabolism of plasmalogens in myocardium

1989 • 27 citations

Relationship between arachidonate generation and exocytosis in permeabilized mast cells

1990 • 27 citations

Phosphoinositides and their products in the mammalian sperm acrosome reaction.

1990 • 27 citations

The pericardium as a source of prostacyclin in the dog, ox and rat

1982 • 27 citations

IMMUNOHISTOCHEMICAL LOCALIZATION OF PHOSPHOLIPASE A2 IN HUMAN PANCREAS IN ACUTE AND CHRONIC PANCREATITIS

1983 • 26 citations

Renal Prostaglandins and Phospholipase A2 in Spontaneously Hypertensive Rats

1987 • 26 citations

Phospholipase A in acute lung injury after trauma and sepsis: Its relation to the inflammatory mediators PMN-elastase, C3a, and neopterin

1989 • 26 citations

Arachidonic acid metabolites and the regulation of placental and other vascular tone during pregnancy.

1986 • 26 citations

The phospholipase A2 of human spermatozoa; purification and partial sequence

1992 • 25 citations

Activity of phospholipase A compared in serum of patients with pancreatic and nonpancreatic diseases.

1987 • 25 citations

Application of a New Monoclonal Antibody for Time-resolved Fluoroimmunoassay of Human Pancreatic Phospholipase A2

1991 • 25 citations

Serum phospholipase — Regulatory and pathophysiological aspects

1989 • 25 citations

Studies on Phospholipase A Inhibitor in Blood Plasma1

1984 • 25 citations

Decreased Phospholipase A2 Activity in Plasma and Liver in Uncontrolled Diabetes Mellitus: A Defect in the Early Steps of Prostaglandin Synthesis?

1986 • 24 citations

Phospholipase A2 Activation is the Pivotal Step in the Effector Pathway of Inflammation

1990 • 24 citations

Structure of genomic DNA for rat platelet phospholipase A2

1990 • 24 citations

Involvement of Phospholipase A Activity in the Plasma Membrane of the Rat Corpus Luteum during Luteolysis*

1987 • 24 citations

Amiodarone- and Desethylamiodarone-induced Pulmonary Phospholipidosis, Inhibition of Phospholipases In Vivo, and Alteration of [14C]Amiodarone Uptake by Perfused Lung

1991 • 24 citations

Isolation and characterization of a membrane-associated, calcium-dependent phospholipase A2 from rabbit lung

1982 • 24 citations

A Unique Phospholipase A2 in Human Epidermis: Its Physiologic Function and Its Level in Certain Dermatoses

1988 • 24 citations

A unique cardiac cytosolic acyltransferase with preferential selectivity for fatty acids that form cyclooxygenase/lipoxygenase metabolites and reverse essential fatty acid deficiency

1985 • 24 citations

Prostaglandins and the Inflammatory Response

1983 • 23 citations

Platelet-activating factor (PAF) acetylhydrolase activity, type II phospholipase A2, and cytokine levels in patients with sepsis.

1994 • 23 citations

Isolation and characterization of phospholipase A2 from rat lung with affinity chromatography and two-dimensional gel electrophoresis

1989 • 23 citations

Activity of phospholipase A2 in plasma increases in uremia

1990 • 23 citations

Elevated maternal plasma immunoreactive phospholipase A2 in human preterm and term labour.

1992 • 23 citations

Characterization and solubilization of membrane bound diacylglycerol lipases from bovine brain

1986 • 23 citations

A phospholipase A2 isoenzyme provokes lipoxin B formation from endogenous sources of arachidonic acid in porcine leukocytes

1987 • 23 citations

Relative abundance of human placental phospholipase A2 messenger RNA in late pregnancy

1992 • 22 citations

Enzymatic activity and distribution of phospholipase A2 in human cartilage

1991 • 22 citations

Group I and Group II Phospholipase A2 in Serum during Normal and Pathological Pregnancy

1993 • 22 citations

Isolation and Characterization of cDNA Clones from Human Placenta Coding for Phospholipase A2

1990 • 22 citations

The Origin of Phagocytic Cells in the Joint and Bone

1981 • 22 citations

Phospholipid metabolism and prostacyclin synthesis in hypoxic myocytes

1991 • 22 citations

Preliminary studies on phospholipase A2‐induced mouse paw edema as a model to evaluate antiinflammatory agents

1989 • 22 citations

Synovial‐type (group II) phospholipase A2 in serum of febrile patients with haematological malignancy

1993 • 22 citations

Expression, purofocation and biochemical comparison of natural and recombinant human non-pancreatic phospholipase A2

1992 • 22 citations

Human placental phospholipase A2 activity in term and preterm labour

1992 • 21 citations

Phospholipase A2 engineering: Design, synthesis, and expression of a gene for bovine (pro)phospholipase A2

1989 • 21 citations

Phospholipase A2 expression in human and rodent insulin-secreting cells

1995 • 21 citations

Relationships between plasma levels of type-II phospholipase A2, PAF-acetylhydrolase, leukotriene B4, complements, endothelin-1, and thrombomodulin in patients with sepsis.

1994 • 21 citations

The role of phospholipase A2 in the physiopathology of osteoarthritis.

1991 • 21 citations

Mechanism of lysophosphatidylcholine accumulation in the ischemic canine heart

1990 • 20 citations

Synthesis and release of phospholipase A2 by unstimulated human articular chondrocytes.

1990 • 20 citations

Purification and characterization of phospholipase A2 from rat stomach

1990 • 20 citations

Soluble Phospholipase A2 in Human Pathology: Clinical-Laboratory Interface

1990 • 20 citations

Elevation of serum group II phospholipase A2 in patients with cancers of digestive organs.

1991 • 20 citations

Properties and localization of phospholipase A2 activity in rat stomach

1987 • 20 citations

Serum Immunoreactive Pancreatic Phospholipase A2 in Patients with Various Malignant Tumors

1990 • 20 citations

Renal phospholipase C and diglyceride lipase activity in spontaneously hypertensive rats.

1987 • 20 citations

Novel seminal phospholipase A2 is inhibited by the major proteins of bovine seminal plasma

1997 • 20 citations

Mechanism of enhanced eicosanoid production by isolated glomeruli from rats with bilateral ureteral obstruction

1991 • 20 citations

Phospholipase A2 activation by interleukin 1: Release and metabolism of arachidonic acid by IL 1-stimulated rabbit chondrocytes

1987 • 19 citations

Work in progress. Occurence of phospholipase A1 and A2 in human decidua

1975 • 19 citations

Rapid determination of phospholipase A in human serum and plasma.

1987 • 19 citations

Modulation of phospholipase A2 activity in human synovial fluid by cations

1987 • 19 citations

Group II Phospholipase A2in Nasal Fluid, Mucosa and Paranasal Sinuses

1997 • 19 citations

Synthesis of a naphthylvinyl-labeled glycerol ether analog of phosphatidylcholine and its use in the assay of phospholipase A2.

1987 • 19 citations

Phospholipase A2 activity in human osteoarthritic cartilage.

1989 • 18 citations

Collagens stimulate the production of mononuclear cell factor (MCF) and prostaglandins (PGE2) by human monocytes.

1980 • 18 citations

PHOSPHOLIPASE C ACTIVITY IN HUMAN ENDOMETRIUM: ITS SIGNIFICANCE IN ENDOMETRIAL PATHOLOGY

1987 • 18 citations

Redox state of free nicotinamide-adenine nucleotides in the cytoplasm and mitochondria of alveolar macrophages

1971 • 18 citations

Nitrite/nitrate (NOX) and type II phospholipase A2, leukotriene B4, and platelet-activating factor levels in patients with septic shock.

1996 • 18 citations

α‐Lecithin: Cholesterol Acyltransferase Deficiency

1987 • 18 citations

Prognostic value of serum phospholipase A in acute pancreatitis

1989 • 18 citations

Immunoreactive forms of human pancreatic chymotrypsin in normal plasma.

1979 • 18 citations

Calcium-dependent binding of calmodulin to phospholipase A2 subunits induces enzymatic activation

1985 • 17 citations

Phospholipase A2 treatment of lymphocytes provides helper signal for interferon-gamma induction. Evidence for second messenger role of endogenous arachidonic acid.

1987 • 17 citations

Purification and immunological characterization of human pancreatic ribonuclease.

1982 • 17 citations

Induction of release of secretory nonpancreatic phospholipase A2 from human articular chondrocytes.

1995 • 17 citations

Stimulation of prostaglandin E2 synthesis in chondrocytes by a factor derived from activated macrophages

1982 • 16 citations

Signal response transduction in rabbit neutrophil leucocytes

1987 • 16 citations

Pharmacological Control of Phospholipase A2 Activity In Vitro and In Vivo

1990 • 16 citations

Action of phospholipase A2 of rabbit neuronal and glial cells on 1,2-diacyl-, 2-acyl-1-alk-1?-enyl-, and 2-acyl-1-alkyl-glycerophosphatides

1981 • 15 citations

Development and use of ELISA to quantify type II phospholipase A2 in normal and uremic serum

1995 • 15 citations

Phospholipase A2 and prostaglandins in human seminal plasma.

1978 • 15 citations

Characterisation of soluble and cell associated phospholipase A2 from rheumatoid synovial fluid.

1989 • 15 citations

Involvement of periodic deacylation-acylation cycles of mitochondrial phospholipids during Sr2+-induced oscillatory ion transport in rat liver mitochondria

1982 • 15 citations

Phospholipase A2 activity of rat stomach

1987 • 15 citations

PLASMA PHOSPHOLIPASE A2 ACTIVITY IN CLINICAL ACUTE MYOCARDIAL INFARCTION

1992 • 15 citations

Membrane-associated phospholipase A2 stimulates DNA synthesis in two murine fibroblasts.

1992 • 15 citations

Macrophage Phospholipase A2 Activity and Eicosanoid Production: Studies with Phospholipase A2 Inhibitors in P388D1 Cells

1990 • 15 citations

Clinical Usefulness of Serum Phospholipase A2 Determination in Patients with Pancreatic Diseases

1991 • 15 citations

Phospholipase A2 in human ascitic fluid. Purification, characterization and immunochemical detection

1991 • 15 citations

The role of phospholipase in the genesis of reperfusion arrhythmia

1986 • 14 citations

Preterm labor and bacterial intra-amniotic infection: Arachidonic acid liberation by the action of phospholipase A2

1988 • 14 citations

Detection of Human Pancreatic Pro-Phospholipase A2 Activation Using an Immunoassay for the Free Activation Peptide DSGISPR

1991 • 14 citations

Usefulness of determination of serum immunoreactive pancreatic phospholipase A2 content for early identification of severe acute pancreatitis.

1986 • 14 citations

Modulation of phospholipase A2 activity in human endometrium and amniotic membrane by steroid hormones

1987 • 13 citations

Serum phospholipase A in hospitalized patients

1989 • 13 citations

Aprotinin and Na2CaEDTA in Experimental Hemorrhagic Pancreatitis in Pigs

1987 • 13 citations

Purification and Characterization of a Phospholipase A2 from Human Osteoarthritic Synovial Fluid

1990 • 13 citations

Long-term ethanol ingestion causes an increase of phospholipase A2 activity in acute experimental pancreatitis in rats

1986 • 13 citations

Purification and Characterization of Ca2+-Dependent Phospholipases A2from Rat Kidney

1996 • 12 citations

Involvement of platelet‐activating factor in zymosan‐induced rat pleurisy

1991 • 12 citations

Extracellular phospholipase A2 activity in cell free peritoneal lavage fluid from mice with zymosan peritonitis

1989 • 12 citations

Rheumatoid arthritis synovial fluid phospholipase A2 activating protein (PLAP) stimulates human neutrophil degranulation and superoxide ion production

1989 • 12 citations

Purification of recombinant human secretory phospholipase A2 (Group II) produced in long-term immobilized cell culture

1992 • 12 citations

The role of phospholipase A2 in human acute pancreatitis

1989 • 12 citations

Crystallographic refinement of bovine pro-phospholipase A2 at 1.6 Å resolution

1991 • 12 citations

Detection and characterization of extracellular phospholipase A2 in pleural effusion of patients with tuberculosis

1991 • 11 citations

An independent crystallographic refinement of porcine phospholipase A2 at 2.4 Å resolution

1991 • 11 citations

Differentiating two forms of plasma lipase by use of media with different ionic strengths.

1984 • 11 citations

The Effect of Early Pancreatectomy and Peritoneal Lavage on the Development of Experimental Haemorrhagic Pancreatitis in Pigs

1982 • 11 citations

Studies on sperm antigenicity. 2. in vivo and in vitro cellular reactivity in guinea pigs sensitized to homologous and heterologous spermatozoal autoantigens

1975 • 11 citations

Effects of chronic administration of doxorubicin on heart phospholipase A2 activity and synthesis and degradation of prostaglandins in rats

1987 • 11 citations

Phospholipase A2-induced pleural inflammation in rats.

1989 • 11 citations

Characterization of phospholipase A2 from rabbit lung microsomes

1987 • 10 citations

Serum phospholipase A2 activity in patients with rheumatoid arthritis before and after treatment with methotrexate, auranofin, or combination of the two.

1996 • 10 citations

A Novel, Vasoactive Product and Plasminogen Activator from Afferent Lymph Cells Draining Chronic Inflammatory Lesions

1979 • 10 citations

Rapid determination of phospholipase A in human serum and plasma.

1987 • 10 citations

Membrane-associated phospholipase A2 detected by a radioimmunoassay is a sensitive marker of inflammation in rheumatoid arthritis.

1992 • 9 citations

Purification and characterization of a phospholipase A2 associated with rabbit lung microsomes: some evidence for its mitochondrial origin

1990 • 9 citations

Phospholipase activity in synovial fluid from patients with rheumatoid arthritis, osteoarthritis and crystal-associated arthritis.

1990 • 9 citations

Calcium Ionophore-Activated Neutrophils Prestimulated with Endotoxin Increase Pulmonary Arterial Pressure and Vascular Leakage in Isolated Perfused Rat Lungs: Role of Platelet-Activating Factor

1991 • 9 citations

The role of phospholipase a2 in pancreatic acinar cell injury

1991 • 9 citations

Dynamics and Participation of Type II Phospholipase A2 in Rat Zymosan-Induced Pleurisy1

1993 • 9 citations

Release of Lysosomal Phospholipase A1 and A2 into Cytosol and Rapid Turnover of Newly-Formed Lysophosphatidylcholine in FL Cells during Fusion-from-within Induced by Measles Virus1

1982 • 9 citations

Studies on phospholipase A2 in human seminal plasma

1992 • 9 citations

Hydrolysis of phosphatidylinositol by human endometrium: modulating effects of steroids on arachidonic acid and 1,2-diacylglycerol release

1988 • 9 citations

Activation Of Phospholipase A2 in Rheumatoid Arthritis

1990 • 9 citations

Study of the excretion in bile and concentration in the gall bladder wall of rifamide.

1966 • 9 citations

Ueber die Verdaulichkeit des Nucleins und Lecithins

1878 • 8 citations

Phospholipase A2 (PLA2) activity in bovine pulmonary artery endothelial cells

1991 • 8 citations

Subcellular localization of rat gastric phospholipase A2

1991 • 8 citations

Phospholipase A2 activity in T‐lymphocytes

1986 • 8 citations

Urinary phospholipase A2 excretion in chronic pancreatic diseases

1992 • 8 citations

Elevation of serum phospholipase A2 in patients at an intensive care unit

1991 • 7 citations

Effects of mepacrine and p-bromophenacyl bromide on anti-IgE and phospholipase A2-induced histamine release from human basophils

1986 • 7 citations

Renal Tubular Dysfunction in Pancreatic Cancer and Chronic Pancreatitis

1989 • 7 citations

Phospholipase A2-induced lung edema and its mechanism in isolated perfused guinea pig lung

1990 • 7 citations

Phospholipase A2 (PLA2) Releases Lipoxins and Leukotrienes from Endogenous Sourcesa,b

1988 • 7 citations

Ectophospholipase A<sub>2</sub> Activity of the Rabbit Peritoneal Neutrophil

1987 • 6 citations

Prostaglandins and their precursors in rheumatoid arthritis: progress and problems.

1982 • 6 citations

<b>Endothelin action on rat uterus is inhibited by an inhibitor of protein kinase C and by inhibitors of the phospholipase A<sub>2</sub>-arachidonic acid-lipoxygenase </b><b>pathway </b>

1990 • 6 citations

Serum phospholipase A2 and lysolecithin changes following myocardial infarction

1992 • 6 citations

Determination of the Catalytic Activity of Phospholipase A2: E. coli-Based Assay Compared to a Photometric Micelle Assay

1993 • 6 citations

Immunocytochemical demonstration of rabbit ribonuclease and phospholipase A2 by the peroxidase-antiperoxidase technique in professional phagocytes (pulmonary alveolar macrophages and granulocytic and mononuclear peritoneal exudate cells) and in glycol methacrylate sections of dermal tuberculous (BCG) lesions.

1983 • 6 citations

A simple isotopic assay method for human serum phospholipase A2activity

1987 • 6 citations

Increased Serum Phospholipase A2 Activity in Advanced Chronic Liver Disease as an Expression of the Acute Phase Response

1993 • 6 citations

Time-resolved fluoroimmunoassay of pancreatic phospholipase A2

1989 • 5 citations

Use of a new simplified assay for phospholipase A2 to measure bacterial enzyme levels

1990 • 5 citations

Activation of group II phospholipase A2 gene via two distinct mechanisms in rat vascular smooth muscle cells.

1991 • 5 citations

Changes of phospholipase A2 inhibitory activity in the K+-sensitive actin gelation factor during the differentiation of myeloid leukemia cells

1987 • 5 citations

Differentiation of Human Phospholipase A2 Isoenzymes in Serum and Other Body Fluids with Use of Monoclonal Antibodies

1993 • 4 citations

Cyclooxygenase — Independent pathway of phospholipase activation in carrageenan — Induced platelet aggregation

1987 • 4 citations

Characterization and pharmacological modulation of soluble phospholipase A2 generated during glycogen-induced rat peritonitis

1992 • 4 citations

Phospholipase activity in intact rat glycogen-elicited neutrophils

1986 • 4 citations

Plasma phospholipase A2 and pancreatic secretory trypsin inhibitor as markers for pancreas graft rejection.

1994 • 3 citations

Characterization of extracellular phospholipase A2 (PLA2) activity in fluid and peritoneal cells from casein-treated rats

1990 • 3 citations

Synaptic vesicle-bound phospholipase(s) acting on phosphatidylinositol exhibit(s) high susceptibility to brain ischemia

1990 • 3 citations

The role of taurocholic acid, glycocholic acid and lysolecithin in experimental stress ulcer in the rat.

1981 • 3 citations

Serum phospholipase A in hematological diseases

1989 • 3 citations

Lipocortins and phospholipase A2 regulation

1990 • 3 citations

Carnitine and Lung Lavage Dipalmitoyl Phosphatidylcholine in War-Gas Injured Patients

2015 • 3 citations

A rapid phospholipase A2 bioassay using14C-oleate-labelledE. coli bacterias

1989 • 2 citations

Serum Phospholipase A2 and Free Fatty Acid Levels in Acute Pancreatitis

1991 • 1 citations

Murine macrophage phospholipase A2

1991 • 1 citations

A possible link betkeen phospholipase A2-prostaglandin system and purines in the control of glial cultured cell differentiation

1990 • 1 citations

[Phospholipase A2--acute phase protein after liver surgery?].

1997 • 1 citations

Carnitine, its role in lung and heart disorders : prceedings of a satellite symposium on the occasion of the Central European Congress for Anesthesiology (ZAK), Graz (Austria), September 13, 1985

1987 • 1 citations

[Phospholipase A2 levels during labor].

1988 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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