Stimulus-specific induction of phospholipid and arachidonic acid metabolism in human neutrophils

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT

1973 • 2,955 citations

Arachidonic acid metabolism in polymorphonuclear leukocytes

1979 • 812 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

The role of calcium in cell death

1981 • 637 citations

ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing biosignaling.

1984 • 389 citations

MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM HUMAN LEUKOCYTES

1973 • 346 citations

Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system.

1985 • 315 citations

Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids.

1979 • 297 citations

Phospholipase A2 and phospholipase C activities of platelets. Differential substrate specificity, Ca2+ requirement, pH dependence, and cellular localization.

1980 • 287 citations

Release and metabolism of arachidonic acid in human neutrophils.

1981 • 281 citations

Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils.

1984 • 270 citations

Statistics for the Biological Sciences

1969 • 269 citations

Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages.

1982 • 247 citations

Leukotriene B4 and phosphatidic acid are calcium ionophores. Studies employing arsenazo III in liposomes.

1982 • 241 citations

Leukotriene B4 is a complete secretagogue in human neutrophils: A kinetic analysis

1982 • 237 citations

Arachidonic acid metabolism in purified human lung mast cells.

1984 • 234 citations

cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils.

1981 • 208 citations

Diacylglycerol, 1-oleoyl-2-acetyl-glycerol, stimulates superoxide-generation from human neutrophils

1984 • 189 citations

Chemotactic factor causes rapid decreases in phosphatidylinositol,4,5-bisphosphate and phosphatidylinositol 4-monophosphate in rabbit neutrophils

1983 • 188 citations

Modulation of phosphatidylinositol-specific phospholipase C activity by phospholipid interactions, diglycerides, and calcium ions.

1982 • 158 citations

Lipoxygenase products of arachidonic acid modulate biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human neutrophils via phospholipase A2.

1985 • 154 citations

Studies on the mechanism of superoxide release from human neutrophils stimulated with arachidonate.

1984 • 145 citations

Mobilization of arachidonic acid in human platelets kinetics and Ca2+ dependency

1977 • 141 citations

Arachidonate metabolism by human polymorphonuclear leukocytes stimulated by N-formyl-Met-Leu-Phe or complement component C5a is independent of phospholipase activation.

1983 • 137 citations

Characterization of the secretory activity of leukotriene B4 toward rabbit neutrophils.

1982 • 122 citations

Stimulation of arachidonic acid metabolism in the polymorphonuclear leukocyte by an N-formylated peptide. Comparison with ionophore A23187.

1980 • 109 citations

Macrophage fatty acid composition and phagocytosis: effect of unsaturation on cellular phagocytic activity.

1979 • 106 citations

Role of Ca2+ in phosphatidylinositol response and arachidonic acid release in formylated tripeptide- or Ca2+ ionophore A23187-stimulated guinea pig neutrophils.

1983 • 96 citations

Leukotriene D4 treatment of bovine aortic endothelial cells and murine smooth muscle cells in culture results in an increase in phospholipase A2 activity.

1986 • 90 citations

Modulation of enzyme activities in isolated lymphocyte plasma membranes by enzymatic modification of phospholipid fatty acids.

1981 • 87 citations

Leukotriene B4 mobilizes calcium without the breakdown of polyphosphoinositides and the production of phosphatidic acid in rabbit neutrophils.

1984 • 86 citations

Endogenous phospholipid metabolism in stimulated neutrophils differential activation by FMLP and PMA

1982 • 83 citations

Characterization of formylmethionyl-leucyl-phenylalanine stimulation of inositol trisphosphate accumulation in rabbit neutrophils.

1985 • 82 citations

Intracellular retention of the 5-lipoxygenase pathway product, leukotriene B4, by human neutrophils activated with unopsonized zymosan.

1985 • 81 citations

Phospholipid and neutral lipid separation by one-dimensional thin-layer chromatography

1982 • 80 citations

Phagocytosis-induced release of arachidonic acid from human neutrophils

1979 • 75 citations

Receptor-mediated activation of a phospholipase A2 in rabbit neutrophil plasma membrane.

1984 • 66 citations

Choline Uptake in Cultured Human Y79 Retinoblastoma Cells: Effect of Polyunsaturated Fatty Acid Compositional Modifications

1982 • 51 citations

Biochemical signal transmitted by Fc gamma receptors: phospholipase A2 activity of Fc gamma 2b receptor of murine macrophage cell line P388D1.

1982 • 46 citations

Surface contact inhibits neutrophil superoxide generation induced by soluble stimuli.

1985 • 45 citations

Leukotriene B4 and phosphatidic acid are calcium ionophores

1984 • 43 citations

Isothermal regulation of membrane fluidity in murine fibroblasts with altered phospholipid polar head groups

1978 • 41 citations

Modification of positional distribution of fatty acids in phosphatidylinositol of rabbit neutrophils stimulated with formylmethionyl-leucyl-phenylalanine

1983 • 32 citations

Enhanced Phospholipase A2 and C Activities of Peripheral Blood Polymorphonuclear Leukocytes From Patients With Rheumatoid Arthritis

1985 • 30 citations

Effects of membrane fatty acid composition on sodium‐independent phenylalanine transport in Ehrlich cells

1979 • 26 citations

Macrophage Fcγ_2b receptor expression and receptor‐ mediated phospholipase activity: regulation by endogenous eicosanoids

1985 • 13 citations