Cyclic AMP mimics, but does not mediate, interleukin-1- and tumour-necrosis-factor-stimulated phospholipase A2 secretion from rat renal mesangial cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

TUMOR NECROSIS, CACHEXIA, SHOCK, AND INFLAMMATION: A COMMON MEDIATOR

1988 • 814 citations

Forskolin: its biological and chemical properties.

1986 • 566 citations

Role of secretory phospholipases A2 in the pathobiology of disease.

1986 • 382 citations

K-252a, a potent inhibitor of protein kinase C from microbial origin.

1986 • 332 citations

Effects of Adenosine Nucleosides on Adenylate Cyclase, Phosphodiesterase, Cyclic Adenosine Monophosphate Accumulation, and Lipolysis in Fat Cells

1972 • 321 citations

The rapid formation of inositol phosphates in human platelets by thrombin is inhibited by prostacyclin.

1984 • 319 citations

Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin. Inhibitory effects of phorbol ester.

1985 • 292 citations

Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: role in the induction of interleukin 6.

1988 • 288 citations

Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP.

1988 • 261 citations

Interleukin 1 activates phospholipase A2 in rabbit chondrocytes: a possible signal for IL 1 action.

1986 • 259 citations

Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis.

1978 • 253 citations

Inhibition of adenylate cyclase by adenosine analogues in preparations of broken and intact human platelets. Evidence for the unidirectional control of platelet function by cyclic AMP

1978 • 246 citations

Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide

1989 • 220 citations

Stimulation of rat mesangial cell proliferation by macrophage interleukin 1.

1983 • 219 citations

Interleukin 1 and tumor necrosis factor synergistically stimulate prostaglandin synthesis and phospholipase A2 release from rat renal mesangial cells

1989 • 193 citations

Chemotactic factor causes rapid decreases in phosphatidylinositol,4,5-bisphosphate and phosphatidylinositol 4-monophosphate in rabbit neutrophils

1983 • 188 citations

Cyclic AMP--an intracellular second messenger for interleukin 1.

1988 • 182 citations

The interleukin 1 gene is expressed by rat glomerular mesangial cells and is augmented in immune complex glomerulonephritis.

1987 • 159 citations

Amiloride directly inhibits growth factor receptor tyrosine kinase activity.

1985 • 155 citations

Interleukin 1: more than a mediator between leukocytes

1988 • 120 citations

Tumor necrosis factor and interleukin-1: role in acute inflammation and microvascular injury.

1987 • 119 citations

Cross‐talk between transmembrane signalling systems: a prerequisite for the delicate regulation of glomerular haemodynamics by mesangial cells

1989 • 109 citations

Co-existence of vimentin and desmin type intermediate filaments in a subpopulation of adult rat vascular smooth muscle cells growing in primary culture

1982 • 107 citations

The proinflammatory effect of intra-articular injection of soluble human and venom phospholipase A2.

1989 • 107 citations

Tumor necrosis factor stimulates prostaglandin production and cyclic AMP levels in rat cultured mesangial cells

1988 • 105 citations

Hormonal activation of the cAMP-dependent protein kinases in AtT20 cells. Preferential activation of protein kinase I by corticotropin releasing factor, isoproterenol, and forskolin.

1984 • 104 citations

Endogenous suppression of neutral-active and calcium-dependent phospholipase A2 in human polymorphonuclear leukocytes

1986 • 102 citations

Activation of phospholipase C and prostaglandin synthesis by [arginine]vasopressin in cultures

1984 • 94 citations

Interleukin‐1 activates phospholipase a₂ IN HUMAN SYNOVIAL CELLS

1988 • 87 citations

Selective Release of Phospholipase A2 and Lysophosphatidylserine- Specific Lysophospholipase from Rat Platelets1

1987 • 86 citations

Extracellular phospholipase A2 mediates inflammatory hyperaemia

1981 • 82 citations

Role of prostaglandins in hypoxia-stimulated erythropoietin production

1985 • 78 citations

Role of phospholipase C and protein kinase C in vasoconstrictor-induced prostaglandin synthesis in cultured rat renal mesangial cells

1986 • 75 citations

Enhancement of glomerular mesangial cell neutral proteinase secretion by macrophages: role of interleukin 1.

1986 • 71 citations

Cell cycle-dependent interleukin 1 gene expression by cultured glomerular mesangial cells.

1988 • 62 citations

The selective release of phospholipase A2 by resident mouse peritoneal macrophages

1981 • 61 citations

Coupling of polyphosphoinositide breakdown with calcium efflux in formyl‐methionyl‐leucyl‐phenylalanine‐stimulated rabbit neutrophils

1983 • 60 citations

Interleukin I and the glomerular mesangium. II. Monokine stimulation of mesangial cell prostanoid secretion.

1987 • 60 citations

Evidence that amiloride antagonises insulin‐stimulated protein phosphorylation by inhibiting protein kinase activity

1983 • 60 citations

Interleukin 1 potentiates the secretion of beta-endorphin induced by secretagogues in a mouse pituitary cell line (AtT-20).

1989 • 57 citations

IL-1 signaling for IL-2 production in T cells involves a rise in phosphatidylserine synthesis.

1988 • 54 citations

Eicosanoids and control of mesangial cell contraction.

1988 • 53 citations

Activation of rabbit articular chondrocytes by recombinant human cytokines.

1987 • 50 citations

Tumor necrosis factor and interleukin 1 activate phospholipase in rat chondrocytes

1988 • 47 citations

Release of phospholipase A2 activity from rabbit peritoneal neutrophils by f-Met-Leu-Phe.

1983 • 46 citations

Mesangial cells, effect of monocyte products on proliferation and matrix synthesis.

1982 • 43 citations

Release of phospholipase A₂ activity from rat vascular smooth muscle cells mediated by cAMP

1989 • 43 citations

Interleukin 1 and the glomerular mesangium. III. IL-1-dependent stimulation of mesangial cell protein kinase activity

1988 • 40 citations

Cyclosporin a augments vasoconstrictor-induced rise in intracellular free calcium in rat renal mesangial cells

1988 • 38 citations

Interleukin 1 stimulates prostaglandin synthesis and cyclic AMP accumulation in Swiss 3T3 fibroblasts: Interactions between two second messenger systems

1989 • 38 citations

Cells and Mediators in Glomerulonephritis

1988 • 21 citations

In SituReassociation of the Regulatory and Catalytic Subunits of 3′,5′-Cyclic Adenosine Monophosphate-Dependent Protein Kinase Isoenzymes in AtT20 Cells

1988 • 6 citations