The role of phospholipase a2 in pancreatic acinar cell injury

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Solubilization of membranes by detergents

1975 • 2,909 citations

[1] Preparation of monoclonal antibodies: Strategies and procedures

1981 • 1,787 citations

Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini

1978 • 380 citations

Experimental Pancreatitis in the Rat

1980 • 364 citations

The Cell Biology of Experimental Pancreatitis

1987 • 237 citations

Acute pancreatitis with hyperlipemia: studies with an isolated perfused canine pancreas.

1977 • 202 citations

Elevated plasma phospholipase A2 levels: correlation with the hemodynamic and pulmonary changes in gram-negative septic shock.

1984 • 197 citations

Role of phospholipase A2 in human acute pancreatitis

1989 • 186 citations

Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization.

1989 • 154 citations

Human acute pancreatitis: Its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells

1986 • 144 citations

The Role of Phospholipase A in Acute Pancreatitis

1980 • 139 citations

The Possible Role of Phospholipase a in the Pathogenesis of Acute Pancreatitis

1969 • 121 citations

Aetiology and pathogenesis of pancreatitis. (Current concepts).

1970 • 105 citations

Activation of Proteases in Cerulein-Induced Pancreatitis

1989 • 87 citations

Profiles of pure pancreatic secretions in patients with acute pancreatitis: The possible role of proteolytic enzymes in pathogenesis

1978 • 85 citations

Experimental Pancreatitis in the Rat

1980 • 85 citations

Role of pancreatic enzymes and their substrates in autodigestion of the pancreas. In vitro studies with isolated rat pancreatic acini.

1989 • 82 citations

Time-resolved fluoroimmunoassay of human pancreatic phospholipase A2.

1983 • 81 citations

HUMAN ACUTE PANCREATITIS

1982 • 73 citations

Determination of necrosis in necrotizing pancreatitis

1985 • 63 citations

Improved Method for the Determination of Phospholipase A2 Catalytic Activity Concentration in Human Serum and Ascites

1987 • 58 citations

Experimental Pancreatitis in the Rat

1980 • 57 citations

DATA CONCERNING THE ETIOLOGY AND PATHOLOGY OF HEMORRHAGIC NECROSIS OF THE PANCREAS (ACUTE HEMORRHAGIC PANCREATITIS)

1909 • 51 citations

Immunocytochemical and morphometric analysis of acinar zymogen granules in human acute pancreatitis

1989 • 50 citations

Purification and characterization of human pancreatic phospholipase A2.

1983 • 48 citations

Experimental pancreatitis in the rat. — Ductal factors in sodium taurocholate-induced acute pancreatitis

1984 • 45 citations

Role of Pancreatic Enzymes and Their Substrates in Autodigestion of the Pancreas

1989 • 38 citations

Serum phospholipase A2 in intensive care patients with peritonitis, multiple injury, and necrotizing pancreatitis

1989 • 35 citations

The role of oxygen free radicals in experimental acute pancreatitis in the rat

1989 • 34 citations

The Activation, Purification, and Properties of Rat Pancreatic Juice Phospholipase A2.

1971 • 26 citations

Pneumoperitoneum and an acute abdominal condition caused by spontaneous perforation of a pyometra in an elderly woman: a case report.

1989 • 25 citations

Experimental pancreatitis in the rat. Light and electron microscopical observations on early pancreatic lesions induced by intraductal injection of trypsin, phospholipase A2, lysolecithin and non-ionic detergent

1982 • 24 citations

Fat Necrosis – a Cause of Pancreatic Parenchymal Necrosis?

1978 • 24 citations

The role of bacteria in hemorrhagic pancreatitis.

1968 • 23 citations

Direct ESR Measurement of Free Radicals in Mouse Pancreatic Lesions

1989 • 22 citations

Involvement of cholecystokinin receptors in the adverse effect of glucocorticoids on diet-induced necrotizing pancreatitis.

1989 • 22 citations

Immunohistochemical Localization of Trypsinogen and Trypsin in Acute and Chronic Pancreatitis

1983 • 20 citations

Reinternalization of secretory proteins during membrane recycling in rat pancreatic acinar cells.

1987 • 19 citations

Internalization of cationized ferritin by isolated pancreatic acinar cells.

1986 • 17 citations

Intracellular Distribution of Lipolytic Enzymes in the Rat Pancreas

1968 • 15 citations

Phospholipases and acyltransferases in macrophages

1989 • 15 citations

The generation of lysolecithin by enterokinase in trypsinogen prophospholipase A2 lecithin mixtures, and its relevance to the pathogenesis of acute necrotising pancreatitis

1985 • 14 citations

Alcohol-induced pancreatic injury (Part 2) evolution of pathogenetic theories

1989 • 14 citations

Phospholipase A2 induced diffuse alveolar damage — Effect of indomethacin and dexamethasone upon morphology and plasma-histamine level

1989 • 13 citations

Significance of prostaglandin E2 in acute necrotising pancreatitis in rats.

1989 • 13 citations

Cimetidine Treatment in Acute Experimental Pancreatitis

1980 • 13 citations

Effect of Bile Salt on Amylase Release from Rat Pancreatic Acini

1985 • 12 citations

The role of phospholipase A2 in human acute pancreatitis

1989 • 12 citations

Human Pancreatic Phospholipase A<sub>2 </sub> in Acute Necrotizing Pancreatitis

1989 • 12 citations

Analysis in the Isolated Perfused Cat Pancreas of Factors Implicated in the Pathogenesis of Pancreatitis

1988 • 10 citations

Complement catabolism and chemotaxis in acute pancreatitis

1982 • 10 citations

Early acinar cell changes in caerulein-induced interstitial acute pancreatitis in the rat

1991 • 9 citations

Bacterial infection is not necessary for lethal necrotizing pancreatitis in mice

1989 • 8 citations

Vascular injury associated with acute pancreatitis induced by oil or Na-deoxycholate.

1971 • 7 citations

Lysolecithin concentration in pancreatic tissue during therapy with phospholipase A2-inhibitors in acute necrotizing pancreatitis

1989 • 6 citations

Prostacyclin (PGI2) stabilises hepatic lysosomes during acute experimental pancreatitis in dogs.

1982 • 5 citations

Simultaneous presence of platelet activating factor, leukotriene B4, prostaglandin F1α and F2α in the supernatant of human neutrophils treated with phospholipase A2 of human monocytes

1989 • 5 citations

Isolated acinar cells from rat pancreas in pathogenic studies on acute pancreatitis.

1989 • 5 citations

A comparison of pancreatitis induced by high or low pressure injections of enzymes into the canine pancreatic duct

1989 • 4 citations

Investigations into various pancreatic enzymes

1982 • 4 citations

Intracellular Distribution of Phospholipases in the Rat Pancreas

1971 • 4 citations

Effects of Extracellular Calcium and Magnesium on Bile-Salt-Stimulated Amylase Release from Rat Pancreatic Acini

1986 • 3 citations