Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Biology of interleukin 1

1988 • 1,547 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Cachectin: More Than a Tumor Necrosis Factor

1987 • 1,457 citations

A Controlled Clinical Trial of High-Dose Methylprednisolone in the Treatment of Severe Sepsis and Septic Shock

1987 • 1,434 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

BONE-MARROW TRANSPLANTATION IN A PATIENT WITH THE WISKOTT-ALDRICH SYNDROME

1968 • 873 citations

Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo.

1985 • 788 citations

RAISED SERUM LEVELS OF TUMOUR NECROSIS FACTOR IN PARASITIC INFECTIONS

1986 • 469 citations

Lymphokines

1987 • 459 citations

Combined Hormonal Infusion Simulates the Metabolic Response to Injury

1984 • 448 citations

Phase I study of recombinant tumor necrosis factor in cancer patients.

1987 • 430 citations

Induction of the synthesis of tumor necrosis factor receptors by interferon-gamma.

1986 • 328 citations

The Acute Metabolic Effects of Tumor Necrosis Factor Administration in Humans

1987 • 236 citations

The Primary Role of Lymphoreticnlar Cells in the Mediation of Host Responses to Bacterial Endotoxim

1980 • 212 citations

The Regulation of ACTH Secretion by IL-1

1987 • 132 citations

Use of monoclonal antibodies as sensitive and specific probes for biologically active human gamma-interferon.

1984 • 130 citations

Development and use of a radioimmunoassay for human interleukin-1 beta.

1987 • 106 citations

The processing and collaborative assay of a reference endotoxin

1983 • 56 citations

Studies of conditions and agents that stimulate and inhibit the production of cachectin by macrophages

1984 • 18 citations