Evidence for a catalytic role of phospholipase A in phorbol diester- and zymosan-induced mobilization of arachidonic acid in mouse peritoneal macrophages

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

How is the level of free arachidonic acid controlled in mammalian cells?

1982 • 1,193 citations

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.

1980 • 1,099 citations

THE DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES

1965 • 704 citations

Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets

1983 • 589 citations

Is Cytosolic Ionized Calcium Regulating Neutrophil Activation?

1983 • 471 citations

Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.

1980 • 464 citations

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

1984 • 447 citations

Thin-layer chromatography of the phosphoinositides

1968 • 256 citations

Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages.

1982 • 247 citations

Phospholipid-sensitive calcium-dependent protein kinase: Inhibition by antipsychotic drugs

1981 • 243 citations

The phosphatidylinositol cycle and the regulation of arachidonic acid production

1981 • 230 citations

Formation of lysophosphatidylinositol in platelets stimulated with thrombin or ionophore A23187.

1982 • 201 citations

Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesis

1983 • 199 citations

Pharmacological control of prostaglandin and thromboxane release from macrophages

1978 • 187 citations

Protein kinase C regulation of the receptor-coupled calcium signal in histamine-secreting rat basophilic leukaemia cells

1985 • 186 citations

Release of Ca2+ from a non-mitochondrial store site in peritoneal macrophages treated with saponin by inositol 1,4,5-trisphosphate

1984 • 171 citations

Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes

1984 • 158 citations

Effects of phorbol-12,13-diesters on prostaglandin production and phospholipase activity in canine kidney (MDCK) cells

1977 • 155 citations

Differential effects of calmodulin antagonists on phospholipases A2 and C in thrombin-stimulated platelets.

1981 • 152 citations

Differential activation of platelet phospholipases by thrombin and ionophore A23187.

1981 • 145 citations

Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change.

1984 • 142 citations

Stimulation of prostaglandin synthesis by tumor-promoting phorbol-12, 13-diesters in canine kidney (MDCK) cells. Cycloheximide inhibits the stimulated prostaglandin synthesis, deacylation of lipids, and morphological changes

1978 • 142 citations

Differential activation of phosphatidylinositol deacylation and a pathway via diphosphoinositide in macrophages responding to zymosan and ionophore A23187.

1984 • 123 citations

The activation of phosphatidylinositol-hydrolyzing phospholipase A2 during prostaglandin synthesis in transformed mouse BALB/3T3 cells.

1981 • 104 citations

Role of Ca2+ in phosphatidylinositol response and arachidonic acid release in formylated tripeptide- or Ca2+ ionophore A23187-stimulated guinea pig neutrophils.

1983 • 96 citations

Calcium ionophore enables soluble agonists to stimulate macrophage 5-lipoxygenase.

1985 • 96 citations

Calcium and phospholipid-dependent protein kinase activity in mouse epidermis cytosol. Stimulation by complete and incomplete tumor promoters and inhibition by various compounds

1984 • 96 citations

Inositol and Phosphoinositides

1985 • 89 citations

Two phospholipase pools for prostaglandin synthesis in macrophages

1981 • 89 citations

Source of arachidonic acid for prostaglandin synthesis in Madin-Darby canine kidney cells.

1981 • 72 citations

Ether phospholipids in guinea pig polymorphonuclear leukocytes and macrophages Occurrence of high levels of 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine

1982 • 69 citations

Effect of RNA and protein synthesis inhibitors on the release of inflammatory mediators by macrophages responding to phorbol myristate acetate

1980 • 68 citations

Pharmacological control of leukotriene and prostaglandin production from mouse peritoneal macrophages

1984 • 58 citations

Studies on the enzymatic pathways of calcium ionophore-induced phospholipid degradation and arachidonic acid mobilization in peritoneal macrophages

1985 • 57 citations

Relative degradation of different molecular species of phosphatidylcholine in thrombin-stimulated human platelets.

1984 • 43 citations

Role of enhanced inositol phospholipid metabolism in neutrophil activation

1985 • 35 citations

Intracellular calcium does not appear to be essential for arachidonic acid release from stimulated macrophages as shown by studies with Quin-2

1985 • 27 citations

Effect of calmodulin antagonists on lysosomal enzyme secretion and phospholipid metabolism in guinea-pig macrophages

1982 • 24 citations