Cytochromes P-450 in rats: structures, functions, properties and relevant human forms

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

MOLECULAR BIOLOGY AND EVOLUTION

2021 • 4,185 citations

Pharmacological Reviews

2024 • 2,716 citations

Cytochrome P-450: Structure, Mechanism, and Biochemistry

1986 • 2,703 citations

Drug Metabolism and Disposition

2014 • 2,466 citations

The molecular biology of cytochrome P450s.

1988 • 1,294 citations

The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature

1991 • 1,092 citations

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

1982 • 1,021 citations

The P450 Gene Superfamily: Recommended Nomenclature

1987 • 812 citations

Sexual Dimorphism in the Control of Growth Hormone Secretion*

1985 • 749 citations

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1988 • 717 citations

Molecular Pharmacology

1965 • 715 citations

SOS Repair Hypothesis: Phenomenology of an Inducible DNA Repair Which is Accompanied by Mutagenesis

1975 • 651 citations

Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens

1985 • 640 citations

The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci

1989 • 609 citations

Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes

1985 • 593 citations

Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.

1979 • 576 citations

Structure of human steroid 21-hydroxylase genes.

1986 • 568 citations

Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene.

1986 • 559 citations

Evolution of the P450 gene superfamily:

1990 • 508 citations

Molecular genetics of the P-450 superfamily

1990 • 496 citations

Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P45 0IA1 gene

1990 • 487 citations

Cytochrome P-450 hPCN3, a Novel Cytochrome P-450 IIIA Gene Product That Is Differentially Expressed in Adult Human Liver

1989 • 480 citations

Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy.

1988 • 465 citations

Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues.

1987 • 449 citations

Interactions of hepatic cytochromes P-450 with steroid hormones

1988 • 441 citations

Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta).

1989 • 440 citations

Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.

1986 • 408 citations

The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.

1989 • 407 citations

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

1990 • 387 citations

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue

1989 • 382 citations

Purification and characterization of hepatic microsomal cytochrome P-450

1990 • 379 citations

Characterization of Two Genes Encoding Human Steroid 11β-Hydroxylase (P-45011β)

1989 • 377 citations

Principles and methods of toxicology

1989 • 375 citations

Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest.

1977 • 367 citations

Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta.

1986 • 359 citations

Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes.

1983 • 339 citations

Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.

1987 • 317 citations

Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid.

1985 • 311 citations

Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats.

1984 • 301 citations

Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation.

1986 • 299 citations

Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms.

1980 • 286 citations

Induction of Rat Hepatic N-Nitrosodimethylamine Demethylase by Acetone Is Due to Protein Stabilization

1989 • 277 citations

Primary structure of a cytochrome P-450: coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver.

1982 • 275 citations

Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes.

1982 • 269 citations

Rat hepatic cytochrome P-450 isoenzyme 2c. Identification as a male-specific, developmentally induced steroid 16 alpha-hydroxylase and comparison to a female-specific cytochrome P-450 isoenzyme.

1984 • 268 citations

Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.

1989 • 265 citations

Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymes

1982 • 265 citations

Aromatase Cytochrome P450 in Rat Ovarian Granulosa Cells before and after Luteinization: Adenosine 3′,5′-Monophosphate-Dependent and Independent Regulation. Cloning and sequencing of rat aromatase cDNA and 5′ genomic DNA

1990 • 257 citations

Separation and purification of multiple forms of microsomal cytochrome P-450. Partial characterization of three apparently homogeneous cytochromes P-450 prepared from livers of phenobarbital- and 3-methylcholanthrene-treated rats

1978 • 255 citations

Oxidases and Related Redox Systems

1989 • 252 citations

Characterization of Human Microsomal Cytochrome P-450 Enzymes

1989 • 244 citations

Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1.

1990 • 236 citations

Phenobarbital-induced rat liver cytochrome P-450. Purification and characterization of two closely related isozymic forms.

1982 • 221 citations

Purification and characterization of a minor form of hepatic microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls

1982 • 217 citations

Cytochrome P-450: Biochemistry and biophysics

1990 • 215 citations

Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes

1987 • 201 citations

Cyclic AMP-dependent and -independent Regulation of Cholesterol Side Chain Cleavage Cytochrome P-450 (P-450scc) in Rat Ovarian Granulosa Cells and Corpora Lutea.

1989 • 197 citations

Demonstration in multiple species of inducible hepatic cytochromes P-450 and their mRNAs related to the glucocorticoid-inducible cytochrome P-450 of the rat.

1985 • 194 citations

Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity

1990 • 193 citations

Evolution of cytochrome P-450 proteins.

1987 • 190 citations

Metabolic activation of mutagenic heterocylic aromatic amines from protein pyrolysates

1986 • 187 citations

Complete cDNA and protein sequence of a pregnenolone 16 alpha-carbonitrile-induced cytochrome P-450. A representative of a new gene family.

1985 • 181 citations

Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture.

1986 • 177 citations

Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues.

1986 • 177 citations

Human P450PCN1: Sequence, Chromosome Localization, and Direct Evidence through cDNA Expression That P450PCN1 Is Nifedipine Oxidase

1988 • 164 citations

Induction of microsomal cytochrome P-450 enzymes: The first Bernard B. Brodie lecture at Pennsylvania State University

1986 • 161 citations

cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver

1989 • 159 citations

Purification and characterization of microsomal cytochrome P-450s

1982 • 157 citations

Purification and characterization of two constitutive forms of rat liver microsomal cytochrome P-450.

1982 • 156 citations

Simultaneous purification of multiple forms of rat liver microsomal cytochrome P-450 by high-performance liquid chromatography

1985 • 156 citations

Metabolic oxidation of the carcinogens 4-aminobiphenyl and 4,4'-methylene-bis(2-chloroaniline) by human hepatic microsomes and by purified rat hepatic cytochrome P-450 monooxygenases.

1989 • 154 citations

Amino acid compositions and partial amino acid sequences of three highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, or 3-methylcholanthrene.

1979 • 153 citations

Purification and characterization of the rat liver microsomal cytochrome P-450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism

1984 • 150 citations

Metabolism of N-nitrosodialkylamines by human liver microsomes.

1988 • 149 citations

Metabolic oxidation of carcinogenic arylamines by rat, dog, and human hepatic microsomes and by purified flavin-containing and cytochrome P-450 monooxygenases.

1985 • 148 citations

Human cytochrome P450IIA3: cDNA sequence role of the enzyme in the metabolic of promutagens comparison to nitrosamine activation by human cytochrome P450IIE1

1990 • 145 citations

cDNA-expressed human cytochrome P450s: a new age of molecular toxicology and human risk assessment

1991 • 143 citations

Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver.

1986 • 142 citations

HumanP₁-450gene sequence and correlation of mRNA with genetic differences in benzo(a]pyrene metabolism

1985 • 141 citations

The Rat Clofibrate-InducibleCYP4ASubfamily II. cDNA Sequence of IVA3, Mapping of theCyp4aLocus to Mouse Chromosome 4, and Coordinate and Tissue-Specific Regulation of theCYP4AGenes

1989 • 140 citations

Debrisoquine 4-Hydroxylase: Characterization of a New P450 Gene Subfamily, Regulation, Chromosomal Mapping, and Molecular Analysis of the DA Rat Polymorphism

1987 • 139 citations

Adult male-specific and neonatally programmed rat hepatic P-450 forms RLM2 and 2a are not dependent on pulsatile plasma growth hormone for expression.

1988 • 138 citations

The rat P450IIE1 gene: complete intron and exon sequence, chromosome mapping, and correlation of developmental expression with specific 5' cytosine demethylation.

1988 • 134 citations

Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5

1983 • 132 citations

Olfactory-specific Cytochrome P-450

1989 • 130 citations

Distinct organization of methylcholanthrene- and phenobarbital-inducible cytochrome P-450 genes in the rat.

1984 • 130 citations

Coding nucleotide sequence of 3-methylcholanthrene-inducible cytochrome P-450d cDNA from rat liver.

1984 • 129 citations

Nucleotide sequence of a full-length cDNA coding for 3-methylcholanthrene-induced rat liver cytochrome P-450MC

1984 • 129 citations

Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids. Transcriptional and post-transcriptional regulation.

1987 • 128 citations

Testosterone metabolism by cytochrome P-450 isozymes RLM3 and RLM5 and by microsomes. Metabolite identification.

1983 • 126 citations

Molecular cloning of cDNA for vitamin D₃ 25‐hydroxylase from rat liver mitochondria

1990 • 125 citations

The Rat Clofibrate-InducibleCYP4AGene Subfamily I. Complete Intron and Exon Sequence of theCYP4A1andCYP4A2Genes, Unique Exon Organization, and Identification of a Conserved 19-bp Upstream Element

1989 • 122 citations

Identification of a new P450 expressed in human lung: complete cDNA sequence, cDNA-directed expression, and chromosome mapping

1989 • 120 citations

A cDNA Encoding a Rat Mitochondrial Cytochrome P450 Catalyzing Both the 26-Hydroxylation of Cholesterol and 25-Hydroxylation of Vitamin D₃: Gonadotropic Regulation of the Cognate mRNA in Ovaries

1990 • 119 citations

Multiplicity, strain differences, and topology of phenobarbital-induced cytochromes P-450 in rat liver microsomes

1982 • 119 citations

Molecular Cloning and Sequence Analysis of cDNA Containing the Entire Coding Region for Human Fetal Liver Cytochrome P-4501

1989 • 118 citations

Transcriptional and post-transcriptional regulation of the genes encoding cytochromes P-450c and P-450d in vivo and in primary hepatocyte cultures.

1988 • 118 citations

Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7α‐hydroxylase

1990 • 114 citations

Cytochrome P450 in livers of diabetic rats: Regulation by growth hormone and insulin

1989 • 113 citations

Identification and localization of amino acid substitutions between two phenobarbital-inducible rat hepatic microsomal cytochromes P-450 by micro sequence analyses.

1983 • 112 citations

Age- and sex-related expression of cytochromes P450f and P450g in rat liver

1986 • 110 citations

Structural analysis and specific expression of microsomal cytochrome P-450(M-1) mRNA in male rat livers.

1987 • 108 citations

Purification and characterization of liver microsomal cytochrome P-450 from untreated male rats

1987 • 107 citations

Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase

1988 • 106 citations

Structure and drug inducibility of the human cytochrome P-450c gene

1986 • 106 citations

Bioactivation and detoxication of the pyrrolizidine alkaloid senecionine by cytochrome P-450 enzymes in rat liver.

1989 • 105 citations

Molecular cloning of cDNA for cholesterol 7α‐hydroxylase from rat liver microsomes

1989 • 105 citations

Complete nucleotide sequence of a methylcholanthrene-inducible cytochrome P-450 (P-450d) gene in the rat.

1985 • 104 citations

Rat testosterone 7 alpha-hydroxylase. Isolation, sequence, and expression of cDNA and its developmental regulation and induction by 3-methylcholanthrene.

1987 • 103 citations

N-demethylation of N-nitrosodimethylamine catalyzed by purified rat hepatic microsomal cytochrome P-450: Isozyme specificity and role of cytochrome b5

1986 • 103 citations

Differential rates of metabolic activation and detoxication of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by different cytochrome P450 enzymes

1990 • 100 citations

The CYP2D gene subfamily: analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats

1989 • 99 citations

The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping

1990 • 98 citations

Molecular cloning and expression of cDNAs encoding rat aldosterone synthase : variants of cytochrome P-450[11β]

1992 • 95 citations

Sequence of two related P-450 mRNAs transcriptionally increased during rat development. An R.dre.1 sequence occupies the complete 3' untranslated region of a liver mRNA.

1986 • 92 citations

Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase

1987 • 91 citations

NH2-terminal sequence analyses of four rat hepatic microsomal cytochromes P-4501

1984 • 88 citations

Purification and characterization of a new form (RLM2) of liver microsomal cytochrome P-450 from untreated rat.

1985 • 85 citations

The structure of cDNA clones encoding the aromatase P-450 isolated from a rat Leydig cell tumor line demonstrates differential processing of aromatase mRNA in rat ovary and a neoplastic cell line

1990 • 85 citations

Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver

1989 • 81 citations

Identification of a novel P450 expressed in rat lung: cDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene

1989 • 79 citations

Activation mechanisms to chemical toxicity

1987 • 79 citations

Glucocorticoid induction of growth hormone synthesis in a strain of rat pituitary cells.

1977 • 78 citations

Responses to insulin by two forms of rat hepatic microsomal cytochrome P-450 that undergo major (RLM6) and minor (RLM5b) elevations in diabetes.

1987 • 74 citations

Rat testis P-45017α cDNA: The deduced amino acid sequence, expression and secondary structural configuration

1988 • 73 citations

Cytochrome P-450-mediated activation of pro-carcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/pSK1002

1987 • 71 citations

Mutagen activation by cDNA‐expressed P₁450, P₃450, and P450a

1989 • 69 citations

Multiple, immunoidentical forms of phenobarbital-induced rat liver cytochromes P-450 are encoded by different mRNAs.

1982 • 68 citations

Physiological and Pathophysiological Alterations in Rat Hepatic Cytochrome P450

1989 • 68 citations

Primary structures of cytochrome P-450 isozyme 5 from rabbit and rat and regulation of species-dependent expression and induction in lung and liver: identification of cytochrome P-450 gene subfamily IVB.

1989 • 67 citations

Gene conversion and differential regulation in the rat P-450 IIA gene subfamily. Purification, catalytic activity, cDNA and deduced amino acid sequence, and regulation of an adult male-specific hepatic testosterone 15 alpha-hydroxylase.

1988 • 66 citations

Amino-terminal and carboxy-terminal sequence of hepatic microsomal cytochrome P-450d, a unique hemoprotein from rats treated with isosafrole

1982 • 66 citations

Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA.

1986 • 65 citations

Isolation of a new human fetal liver cytochrome P450 cDNA clone: Evidence for expression of a limited number of forms of cytochrome P450 in human fetal livers

1989 • 64 citations

Human P₃450: cDNA and complete amino acid sequence

1986 • 64 citations

Genotoxic and mutagenic activation of aflatoxin B1 by constitutive forms of cytochrome P-450 in rat liver microsomes

1987 • 61 citations

Immunochemical study on the role of different types of microsomal cytochrome P-450 in mutagenesis by chemical carcinogens.

1980 • 61 citations

Cloning and Characterization of a Novel Member of the Cytochrome P450 Subfamily IVA in Rat Prostate

1990 • 60 citations

A novel human cytochrome P4S0 gene (P450IIB): chromosomal localization and evidence for alternative splicing

1988 • 58 citations

cDNA and amino acid sequences of two members of the human P450IIC gene subfamily

1987 • 58 citations

Mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline by complementary DNA-expressed human liver P-450.

1990 • 57 citations

Nucleotide Sequence of a Human Liver Cytochrome P-450 Related to the Rat Male Specific Form1

1987 • 53 citations

Hydrodynamic characterization of highly purified and functionally active liver microsomal cytochrome P-450

1979 • 53 citations

Metabolic activation of environmental carcinogens and mutagens by human liver microsomes

1988 • 52 citations

Purification and characterization of two constitutive cytochromes P-450 (F-1 and F-2) from adult female rats: identification of P-450F-1 as the phenobarbital-inducible cytochrome P-450 in male rat liver

1987 • 52 citations

Sequencing of cDNA inserts encoding aromatase cytochrome P-450 (P-450AROM)

1987 • 48 citations

Comparisons of warfarin metabolism by liver microsomes of rats treated with a series of polybrominated biphenyl congeners and by the component-purified cytochrome P-450 isozymes

1983 • 46 citations

cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15 beta-hydroxylation of steroid sulfates.

1988 • 45 citations

Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B₁

1983 • 45 citations

Isolation and characterization of cDNA clones for cytochromes P-450 immunochemically related to rat hepatic P-450 form PB-1

1986 • 37 citations

Olfactory-specific cytochrome P-450 (P-450olf1; IIG1). Gene structure and developmental regulation.

1990 • 37 citations

Further characterization of RLM2 and comparison with a related form of cytochrome P-450, RLM2b

1988 • 36 citations

Purification and Characterization of Six Cytochromes P-450 from Hepatic Microsomes of Immature Female Rats

1987 • 35 citations

The role of highly purified cytochrome P-450 isozymes in the activation of 4-aminobiphenyl to mutagenic products in the Ames test

1983 • 35 citations

Effects of growth hormone on cytochrome P-450j

1988 • 34 citations

A Constitutive Member of the Rat Cytochrome P450IIB Subfamily: Full-Length Coding Sequence of the P450IIB3 cDNA

1988 • 34 citations

Specificity of four forms of cytochrome P-450 in the metabolic activation of several aromatic amines and benzo[a]pyrene

1984 • 33 citations

cDNA cloning of cytochrome P‐450 related to P‐450_p‐2 from the cDNA library of human placenta

1990 • 33 citations

Regulation of cytochrome P-450b and P-450e mRNA expression in the developing rat. Hybridization to synthetic oligodeoxyribonucleotide probes.

1986 • 33 citations

cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3)

1989 • 32 citations

Selective Mutagenic Activation by Cytochrome P3-450 of Carcinogenic Arylamines Found in Foods

1989 • 32 citations

Characterization of a cDNA for rat P-450g, a highly polymorphic, male-specific cytochrome in the P-450IIC subfamily

1989 • 27 citations

Isolation and Comparison of Four Cytochrome P-450 Enzymes from Phenobarbital-Induced Rat Liver: Three Forms Possessing Identical NH<sub>2</sub>-Terminal Sequences

1985 • 27 citations

Metabolic activation of paracetamol by highly purified forms of cytochrome P-450.

1983 • 27 citations

Comparisons of highly purified hepatic microsomal cytochromes P-450 from holtzman and long-evans rats

1982 • 25 citations

Metabolic Activation of Carcinogens and Toxic Chemicals

1988 • 25 citations

Structural and Regulatory Analysis of a Cytochrome P450 Gene (CYP2C12) Expressed Predominantly in Female Rat Liver

1990 • 24 citations

Isolation and Characterization of Rat Cytochrome P-450IIB Gene Family Members

1989 • 20 citations

Aflatoxin B₁ hydroxylation by the pregnenolone-16α-carbonitrile-inducible form of rat liver microsomal cytochrome P-450

1988 • 19 citations

Four species of cDNAs for cytochrome P450 isozymes immunorelated to P450C-M/F encode for members of P450IID subfamily, increasing the number of members within the subfamily

1988 • 17 citations

Activation and inactivation of a variety of mutagenic compounds by the reconstituted system containing highly purified preparations of cytochrome P-450 from rat liver

1985 • 17 citations

Three immunoidentical cytochromes P-450 from liver microsomes of phenobarbital-treated rats

1983 • 14 citations

Comparative study on the metabolism of N-methyl-4-aminoazobenzene by two forms of cytochrome P-488

1985 • 10 citations

Evolution of the P450 gene superfamily.

1988 • 8 citations

Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes

1990 • 8 citations

Age and Sex Differences in Constitutive Forms of Cytochrome P-450 of Rat Liver Microsomes

1986 • 7 citations

Future developments with the cytochromes P-450: promises for the applied chemical and medical sciences

1990 • 6 citations

Chapter 8 Aspects of Application of Cytochrome P-450 and Related Systems in Substrate Hydroxylation and Conversion Processes

1984 • 2 citations

Deleted Work

1955 • 0 citations