Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 3,435 citations

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.

1979 • 576 citations

Microsomes and Drug Oxidations

1970 • 463 citations

Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction.

1981 • 304 citations

Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms.

1980 • 286 citations

Partial purification of cytochromes P-450 and P-448 from rat liver microsomes

1972 • 270 citations

Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymes

1982 • 265 citations

Increased Activity of Androgen Hydroxylases in Liver Microsomes of Rats Pretreated with Phenobarbital and Other Drugs

1963 • 250 citations

Purification and characterization of a minor form of hepatic microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls

1982 • 217 citations

Microsomes, drug oxidations, and drug toxicity

1982 • 187 citations

Preparation of homogeneous NADPH-cytochrome P-450 reductase from rat liver

1975 • 186 citations

Preparation of monospecific antibodies against two forms of rat liver cytochrome P-450 and quantitation of these antigens in microsomes

1979 • 180 citations

Amino acid compositions and partial amino acid sequences of three highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, or 3-methylcholanthrene.

1979 • 153 citations

Oxidative Metabolism of Polycyclic Aromatic Hydrocarbons to Ultimate Carcinogens

1982 • 129 citations

Immunochemical relatedness of rat hepatic microsomal cytochromes P-450c and P-450d.

1982 • 121 citations

Identification and localization of amino acid substitutions between two phenobarbital-inducible rat hepatic microsomal cytochromes P-450 by micro sequence analyses.

1983 • 112 citations

Neonatal imprinting and the turnover of microsomal cytochrome P-450 in rat liver.

1975 • 47 citations

Testosterone oxidation by rat liver microsomes: Effects of phenobarbital pretreatment and the detection of seven metabolites by HPLC

1981 • 45 citations

Stereoselective metabolism of the (+)- and (-)-enantiomers of trans-3,4-dihydroxy-3,4-dihydrobenz[a]anthracene by rat liver microsomes and by a purified and reconstituted cytochrome P-450 system.

1982 • 43 citations

Multiplicity of testosterone hydroxylases in a reconstituted hepatic cytochrome P-450 system from uninduced male rats.

1979 • 42 citations

Induction of testosterone 16β-hydroxylase in rat liver microsomes by phenobarbital pretreatment

1980 • 22 citations

Testosterone inhibition of 6β-, 7α- and 16α-hydroxytestosterone metabolism by rat liver microsomes

1969 • 15 citations

Heterogeneity of testosterone hydroxylases in rat and rabbit liver microsomes. Quantification of major hydroxytesterone metabolites by a thin layer radiochromatographic procedure

1980 • 11 citations

16β‐hydroxylation of 4‐androstene‐3,17‐dione in phenobarbital‐pretreated rat liver microsomes

1980 • 4 citations