Isolation of a new human fetal liver cytochrome P450 cDNA clone: Evidence for expression of a limited number of forms of cytochrome P450 in human fetal livers

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

The P450 Gene Superfamily: Recommended Nomenclature

1987 • 812 citations

Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.

1986 • 408 citations

Human Dioxin-Inducible Cytochrome P ₁ -450: Complementary DNA and Amino Acid Sequence

1985 • 233 citations

Human P450PCN1: Sequence, Chromosome Localization, and Direct Evidence through cDNA Expression That P450PCN1 Is Nifedipine Oxidase

1988 • 164 citations

P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16 alpha-hydroxylase of dehydroepiandrosterone 3-sulfate.

1987 • 160 citations

Structural Characteristics of Cytochrome P-450. Possible Location of the Heme-Binding Cysteine in Determined Amino-Acid Sequences

1983 • 146 citations

The presence of a monooxygenase system in human fetal liver microsomes

1970 • 145 citations

Purification and properties of cytochrome P-450 from homogenates of human fetal livers

1985 • 137 citations

Characterization of mRNA Species Related to Human Liver Cytochrome P-450 Nifedipine Oxidase and the Regulation of Catalytic Activity

1989 • 123 citations

The precursor for carbamyl phosphate synthetase is transported to mitochondria via a cytosolic route.

1979 • 113 citations

Drug Metabolism by the Human Fetus

1980 • 102 citations

Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase

1987 • 91 citations

Characterization of multiple human cytochrome P-450 1 cDNAs. The chromosomal localization of the gene and evidence for alternate RNA splicing.

1987 • 71 citations

Purification of a human liver cytochrome P-450 immunochemically related to several cytochromes P-450 purified from untreated rats.

1987 • 61 citations

Nucleotide Sequence of a Human Liver Cytochrome P-450 Related to the Rat Male Specific Form1

1987 • 53 citations

Hydroxylation of 3,4-benzpyrene in human fetal tissue homogenates

1972 • 53 citations

Cytochrome P-450 Related to P-4504 from Phenobarbital-Treated Rabbit Liver: Molecular Cloning of cDNA and Characterization of Cytochrome P-450 Obtained by Its Expression in Yeast Cells1

1987 • 33 citations

Cytochrome P-450 in Human Liver Microsomes: High-Performance Liquid Chromatographic Isolation of Three Forms and Their Characterization1

1988 • 31 citations

Structural Analysis of Cloned cDNAs for Polycyclic Hydrocarbon-Inducible Forms of Rabbit Liver Microsomal Cytochrome P-4501

1987 • 29 citations

Comparison of primary structures deduced from cDNA nucleotide sequences for various forms of liver microsomal cytochrome P-450 from phenobarbital-treated rabbits

1988 • 29 citations

Microheterogeneity in the major phenobarbital-inducible forms of rabbit liver microsomal cytochrome P-450 as revealed by nucleotide sequencing of cloned cDNAs

1988 • 25 citations

Difference in the Substrate Specificities of Drug Metabolizing Enzymes in Human Term Placenta and Fetal Liver

1973 • 9 citations