Receptor-receptor interactions as an integrative mechanism in nerve cells

On the nature of allosteric transitions: A plausible model

1965 • 8,699 citations

The organization of behavior

1988 • 8,668 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

The Organization of Behavior

2005 • 2,070 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Neurotransmitters and neuromodulators in the basal ganglia

1990 • 1,578 citations

ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS

1979 • 1,370 citations

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

Release of endogenous Zn2+ from brain tissue during activity

1984 • 1,125 citations

Organization of Behavior.

1950 • 1,082 citations

The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.

1970 • 860 citations

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

1991 • 859 citations

Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes.

1986 • 821 citations

Stimulation-induced uptake and release of zinc in hippocampal slices

1984 • 812 citations

Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain

1986 • 742 citations

GABAergic modulation of benzodiazepine binding site sensitivity

1978 • 726 citations

A Glycine Site Associated with N‐Methyl‐<scp>d</scp>‐Aspartic Acid Receptors: Characterization and Identification of a New Class of Antagonists

1989 • 723 citations

Two brain cholecystokinin receptors: implications for behavioral actions

1986 • 719 citations

A subpopulation of mesencephalic dopamine neurons projecting to limbic areas contains a cholecystokinin-like peptide: Evidence from immunohistochemistry combined with retrograde tracing

1980 • 717 citations

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

1977 • 716 citations

Neurotransmitter regulation of dopamine neurons in the ventral tegmental area

1993 • 713 citations

Adenosine receptors and behavioral actions of methylxanthines.

1981 • 705 citations

Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications

1987 • 664 citations

Selective Amplification And Cloning Of Four New Members Of The G Protein-coupled Receptor Family

1989 • 647 citations

Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum

1992 • 646 citations

The Physiological Role of Adenosine In The Central Nervous System

1985 • 628 citations

Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits

1992 • 623 citations

Turning behaviour in animals

1980 • 609 citations

Long-term potentiation in the hippocampus using depolarizing current pulses as the conditioning stimulus to single volley synaptic potentials

1987 • 585 citations

Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons.

1981 • 559 citations

GABA receptor mechanisms in the central nervous system

1991 • 555 citations

Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes.

1991 • 541 citations

Structure and functional expression of the cloned rat neurotensin receptor

1990 • 529 citations

Striatal Restricted Adenosine A₂ Receptor (RDC8) Is Expressed by Enkephalin but Not by Substance P Neurons: An In Situ Hybridization Histochemistry Study

1991 • 527 citations

Modulation of neurotransmission by purine nucleotides and nucleosides

1980 • 526 citations

Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity.

1990 • 501 citations

Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.

1988 • 495 citations

Phenotypical characterization of the rat striatal neurons expressing the D1 dopamine receptor gene.

1991 • 477 citations

G protein-coupled mechanisms and nervous signaling

1992 • 474 citations

Dopamine receptor gene expression by enkephalin neurons in rat forebrain.

1990 • 469 citations

An endogenous protein modulates the affinity of GABA and benzodiazepine receptors in rat brain

1978 • 467 citations

Adenosine as a Neuromodulator

1985 • 462 citations

Adrenergic receptors. Models for the study of receptors coupled to guanine nucleotide regulatory proteins.

1988 • 455 citations

The glycine site of the NMDA receptor — five years on

1993 • 440 citations

Occurrence of neurotensinlike immunoreactivity in subpopulations of hypothalamic, mesencephalic, and medullary catecholamine neurons

1984 • 439 citations

Regulation of neurotransmitter receptor desensitization by protein phosphorylation

1990 • 439 citations

Mechanism of Action of Benzodiazepines

1976 • 437 citations

Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines

1983 • 437 citations

Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors

1992 • 428 citations

Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization

1986 • 414 citations

Ionic Channels and Their Regulation by G Protein Subunits

1990 • 413 citations

Signal transduction by allosteric receptor oligomerization

1988 • 410 citations

Intravesicular localization of zinc in rat telencephalic boutons. A histochemical study

1985 • 410 citations

Regulation of Adenylyl Cyclase-Coupled beta-Adrenergic Receptors

1988 • 389 citations

Volume transmission in the brain. Novel mechanisms for neural transmission

1992 • 388 citations

GABAA receptors: ligand-gated Cl− ion channels modulated by multiple drug-binding sites

1992 • 382 citations

Adenosine-dopamine interactions in the brain

1992 • 366 citations

Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices

1990 • 356 citations

Possible involvement of GABA in the central actions of benzodiazepines.

1975 • 346 citations

Direct autoradiographic localization of adenosine A2 receptors in the rat brain using the A2-selective agonist, [3H]CGS 21680

1989 • 344 citations

Signal sorting and amplification through G protein-coupled receptors

1989 • 338 citations

Modulation of the NMDA receptor by polyamines

1991 • 336 citations

Autoradiographic localization and biochemical characterization of peripheral type CCK receptors in rat CNS using highly selective nonpeptide CCK antagonists

1987 • 331 citations

Mechanisms of signal transduction at the dopamine D2 receptor

1989 • 312 citations

Calcitonin gene-related peptide, a peptide present in spinal cord motoneurons, increases the number of acetylcholine receptors in primary cultures of chick embryo myotubes

1986 • 312 citations

Molecular machines integrate coincident synaptic signals

1993 • 310 citations

Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam.

1990 • 303 citations

Structure of the Adrenergic and Related Receptors

1989 • 300 citations

Function and pharmacology of multiple GABAA receptor subunits

1991 • 292 citations

Inhibition by dopamine of (Na+ + K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism

1990 • 286 citations

Modulation of excitatory amino acid receptors by group IIB metal cations in cultured mouse hippocampal neurones.

1989 • 275 citations

RDC8 codes for an adenosine A2 receptor with physiological constitutive activity

1990 • 270 citations

Calcitonin gene-related peptide and muscle activity regulate acetylcholine receptor alpha-subunit mRNA levels by distinct intracellular pathways.

1987 • 247 citations

Quantal release of neurotransmitter and long-term potentiation

1993 • 237 citations

Characterization of dopamine receptors mediating inhibition of adenylate cyclase activity in rat striatum.

1985 • 236 citations

Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase.

1987 • 235 citations

Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture.

1989 • 225 citations

Regional Brain Concentrations of Neuropeptides in Huntington's Chorea and Schizophrenia

1983 • 223 citations

A kinetic analysis of the modulation of N‐methyl‐D‐aspartic acid receptors by glycine in mouse cultured hippocampal neurones.

1990 • 216 citations

Effects of adenosine on depolarization-induced release of various radiolabelled neurotransmitters from slices of rat corpus striatum

1979 • 210 citations

Calcitonin gene-related peptide enhances the rate of desensitization of the nicotinic acetylcholine receptor in cultured mouse muscle cells.

1988 • 208 citations

G-protein beta gamma dimers. Membrane targeting requires subunit coexpression and intact gamma C-A-A-X domain.

1991 • 203 citations

Adenosine A2 receptors: Selective localization in the human basal ganglia and alterations with disease

1991 • 198 citations

Link between D1 and D2 dopamine receptors is reduced in schizophrenia and Huntington diseased brain.

1989 • 197 citations

Molecular biology of α-adrenergic receptors: implications for receptor classification and for structure-function relationships

1991 • 191 citations

cAMP-dependent protein kinase phosphorylates the nicotinic acetylcholine receptor

1983 • 187 citations

Neocortical long-term potentiation

1993 • 185 citations

In rats, the behavioral profile of CCK-8 related peptides resembles that of antipsychotic agents

1983 • 184 citations

Interactions of neurotensin with brain dopamine systems: biochemical and behavioral studies.

1983 • 184 citations

Fast Kinetic Studies on the Interaction of a Fluorescent Agonist with the Membrane‐Bound Acetylcholine Receptor from Torpedo marmorata

1979 • 183 citations

Cloning and sequence analysis of cDNA for the canine neurotensin/neuromedin N precursor.

1987 • 181 citations

Allosteric modulations of the nicotinic acetylcholine receptor

1993 • 179 citations

Conversion of a gonadotropin-releasing hormone antagonist to an agonist

1982 • 174 citations

Distribution of adenosine A2 receptor mRNA in the human brain

1991 • 173 citations

Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor

1990 • 170 citations

The interaction of neurotensin with dopaminergic pathways in the central nervous system: Basic neurobiology and implications for the pathogenesis and treatment of schizophrenia

1986 • 168 citations

Neuropeptide Y in vitro selectively increases the number of α₂‐adrenergic binding sites in membranes of the medulla oblongata of the rat

1983 • 167 citations

Effects of the selective adenosine A2 receptor agonist CGS 21680 on in vitro electrophysiology, cAMP formation and dopamine release in rat hippocampus and striatum.

1990 • 167 citations

Action of caffeine and theophyllamine on supersensitive dopamine receptors: considerable enhancement of receptor response to treatment with DOPA and dopamine receptor agonists.

1974 • 166 citations

Neurotensin microinjection into the nucleus accumbens antagonizes dopamine-induced increase in locomotion and rearing

1984 • 163 citations

Adenosine modulation of synaptosomal dopamine release

1979 • 158 citations

Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.

1987 • 156 citations

Receptor‐receptor interactions in the central nervous system. A new integrative mechanism in synapses

1985 • 155 citations

Modulation by cholecystokinins of ³H‐spiroperidol binding in rat striatum: evidence for increased affinity and reduction in the number of binding sites

1981 • 155 citations

Autoradiographic evidence for G-protein coupled A2-receptors in rat neostriatum using [3H]-CGS 21680 as a ligand

1990 • 154 citations

Evidence for the existence of receptor--receptor interactions in the central nervous system. Studies on the regulation of monoamine receptors by neuropeptides.

1983 • 150 citations

The Receptors : a comprehensive treatise

1979 • 145 citations

Evidence for involvement of GABA in the action of benzodiazepines: studies on rat cerebellum.

1975 • 141 citations

Activity-dependent regulation of gene expression in muscle and neuronal cells

1989 • 133 citations

Three-dimensional modelling of G protein-linked receptors

1990 • 133 citations

Calcitonin gene-related peptide regulates phosphorylation of the nicotinic acetylcholine receptor in rat myotubes

1989 • 129 citations

Neurotensin in vitro markedly reduces the affinity in subcortical limbic ³H‐N‐propylnorapomorphine binding sites*

1983 • 128 citations

Regulation of receptor function by protein phosphorylation

1987 • 128 citations

Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism.

1991 • 127 citations

Aspects on receptor regulation and isoreceptor identification.

1980 • 126 citations

New vistas on synaptic plasticity: the receptor mosaic hypothesis of the engram.

1982 • 123 citations

The cellular localization of adenosine receptors in rat neostriatum

1989 • 123 citations

beta-FNA binds irreversibly to the opiate receptor complex: in vivo and in vitro evidence.

1988 • 123 citations

Long-term potentiation as synaptic dialogue

1993 • 122 citations

Differential effects of haloperidol and clozapine on neurotensin gene transcription in rat neostriatum

1992 • 120 citations

Endogenous Benzodiazepine Receptor Ligands in Human and Animal Hepatic Encephalopathy

1990 • 119 citations

Substance P enhances cholinergic receptor desensitization in a clonal nerve cell line.

1980 • 119 citations

Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices

1984 • 118 citations

Regulation of glutamate receptor binding by the cytoskeletal protein fodrin

1985 • 116 citations

The G protein connection: molecular basis of membrane association

1991 • 114 citations

Stimulation of adenosine A2 receptors induces catalepsy

1991 • 111 citations

Open channel block of NMDA receptor responses evoked by tricyclic antidepressants

1989 • 109 citations

On the mechanism by which methylxanthines enhance apomorphine-induced rotation behaviour in the rat

1983 • 106 citations

[Action of caffeine on the spontaneous motility of the mouse].

1965 • 105 citations

Modulation of Striatal Dopaminergic Function by Local Injection of 5′- N -Ethylcarboxamide Adenosine

1982 • 104 citations

Specific binding of triatiated neurotensin to rat brain membranes: Characterization and regional distribution

1984 • 104 citations

Noncompetitive inhibition of gamma-aminobutyric acidA channels by Zn.

1991 • 104 citations

Dopamine denervation leads to an increase in the intramembrane interaction between adenosine A2 and dopamine D2 receptors in the neostriatum

1992 • 104 citations

Postsynaptic dopamine/adenosine interaction: II. Postsynaptic dopamine agonism and adenosine antagonism of methylxanthines in short-term reserpinized mice

1991 • 103 citations

Fast Kinetic Studies on the Allosteric Interactions between Acetylcholine Receptor and Local Anesthetic Binding Sites

1979 • 102 citations

Comparison of the behavioral effects of adenosine agonists and dopamine antagonists in mice

1989 • 101 citations

Gating scheme for single GABA-activated Cl- channels determined from stability plots, dwell-time distributions, and adjacent-interval durations

1989 • 101 citations

Fidia Research Foundation Neuroscience award lectures

1991 • 99 citations

Stereospecificity in some central and circulatory effects of phenylisopropyl-adenosine (PIA).

1975 • 99 citations

Caffeine produces contralateral rotation in rats with unilateral dopamine denervation: comparisons with apomorphine-induced responses

1988 • 97 citations

Effects of Caffeine and Theophylline on Activity of Rats in Relation to Brain Xanthine Concentrations

1972 • 97 citations

Effect of some phosphodiesterase inhibitors on central dopamine mechanisms

1976 • 95 citations

Substance P modulation of acetylcholine-induced currents in embryonic chicken sympathetic and ciliary ganglion neurons.

1984 • 95 citations

On the functional role of coexistence of 5‐HT and substance P in bulbospinal 5‐HT neurons. Substance P reduces affinity and increases density of ³H‐5‐HT binding sites

1983 • 95 citations

Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain

1989 • 94 citations

Intramembrane Interactions between Neurotensin Receptors and Dopamine D₂ Receptors as a Major Mechanism for the Neuroleptic‐like Action of Neurotensina

1992 • 93 citations

Dual-component NMDA receptor currents at a single central synapse

1990 • 91 citations

The cellular basis of cerebellar plasticity

1991 • 89 citations

Characterization of normal and supersensitive dopamine receptors: Effects of ergot drugs and neuropeptides

1981 • 88 citations

Galanin selectively modulates 5-hydroxytryptamine 1A receptors in the rat ventral limbic cortex

1988 • 87 citations

Actions of benzodiazepine and beta-carboline derivatives on gamma-aminobutyric acid-activated Cl- channels recorded from membrane patches of neonatal rat cortical neurons in culture.

1987 • 87 citations

Differential modulation by CCK-8 and CCK-4 of [3H]spiperone binding sites linked to dopamine and 5-hydroxytryptamine receptors in the brain of the rat

1983 • 85 citations

The G protein-channel connection

1990 • 85 citations

Polyamine metabolism in reversible cerebral ischemia: effect of α-difluoromethylornithine

1988 • 84 citations

Biochemical and Immunological Studies on Two Distinct Ganglioside-Hydrolyzing Sialidases from the Particulate Fraction of Rat Brain1

1990 • 84 citations

Regulation of the neurotensin receptor and intracellular calcium mobilization in HT29 cells.

1990 • 84 citations

Structural characterization of Y1 and Y2 receptors for neuropeptide Y and peptide YY by affinity cross-linking.

1990 • 82 citations

Evidence for adenosine A2 receptor involvement in the hypomobility effects of adenosine analogues in mice

1989 • 80 citations

Evidence for a substrate of neuronal plasticity based on pre- and postsynaptic neurotensin-dopamine receptor interactions in the neostriatum.

1992 • 79 citations

Adenosine-sensitive adenylate cyclase in rat brain homogenates: kinetic characteristics, specificity, topographical, subcellular and cellular distribution.

1979 • 78 citations

Regulation of ligand binding to pituitary D-2 dopaminergic receptors. Effects of divalent cations and functional group modification.

1983 • 78 citations

Selective labeling of different dopamine receptors by a new agonist 3H-ligand: 3H-N-propylnorapomorphine

1979 • 71 citations

Neurotensin modulates autoreceptor mediated dopamine effects on midbrain dopamine cell activity

1991 • 70 citations

Sensitization by caffeine of central catecholamine receptors

1973 • 70 citations

Crotaline pit organs analyzed as warm receptors

1981 • 69 citations

Purification and Characterization of Naturally Occurring Benzodiazepine Receptor Ligands in Rat and Human Brain

1992 • 68 citations

Neurotensin reduces the affinity of D‐2 dopamine receptors in rat striatal membranes

1987 • 65 citations

Different channel properties of Torpedo acetylcholine receptor monomers and dimers reconstituted in planar membranes.

1984 • 65 citations

Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor

1991 • 64 citations

CCK nerve terminals in the rat striatal and limbic areas originate partly in the brain stem and partly in telencephalic structures

1983 • 63 citations

Neurotensin counteracts apomorphine-induced inhibition of dopamine release as studied by microdialysis in rat neostriatum

1989 • 63 citations

Acetylcholine receptors are not functionally independent

1986 • 63 citations

Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex.

1990 • 63 citations

Substance P modulates single-channel properties of neuronal nicotinic acetylcholine receptors

1990 • 62 citations

Induction of phosphorylation and cell surface redistribution of acetylcholine receptors by phorbol ester and carbamylcholine in cultured chick muscle cells.

1988 • 62 citations

The effects of neurotensin on GABA and acetylcholine release in the dorsal striatum of the rat: an in vivo mirodialysis study

1992 • 61 citations

Chapter 19 Aspects on the information handling by the central nervous system: focus on cotransmission in the aged rat brain

1986 • 61 citations

Inhibition of nigrostriatal release of dopamine in the rat by adenosine receptor agonists: A1 receptor mediation

1989 • 60 citations

Cholecystokinin peptides in vitro modulate the characteristics of the striatal ³H‐N‐propylnorapomorphine sites

1983 • 59 citations

Neuropharmacological Profile of Cholecystokinin‐like Peptides

1985 • 59 citations

Striatal A2 receptor regulates apomorphine-induced turning in rats with unilateral dopamine denervation

1991 • 59 citations

Opposing actions of an adenosine A2 receptor agonist and a GTP analogue on the regulation of dopamine D2 receptors in rat neostriatal membranes

1993 • 58 citations

Dopamine receptor elevation by cholecystokinin

1984 • 57 citations

D-2 dopamine receptor-mediated inhibition of pro-opiomelanocortin synthesis in rat intermediate lobe. Abolition by pertussis toxin or activators of adenylate cyclase.

1986 • 56 citations

Adenosine and adenine nucleotides: Physiology and pharmacology

1989 • 55 citations

Neurotensin Decreases the Affinity of Dopamine D² Agonist Binding by a G Protein‐Independent Mechanism

1991 • 54 citations

Effects of pertussis toxin on D2-dopamine receptor in rat striatum: Evidence for coupling of Ni regulatory protein with D2-receptor

1985 • 54 citations

Studies on neurotensin catecholamine interactions in the hypothalamus and in the forebrain of the male rat

1984 • 54 citations

Different modes of action of 3-amino-1-hydroxy-2-pyrrolidone (HA-966) and 7-chlorokynurenic acid in the modulation of N-methyl-D-aspartate-sensitive glutamate receptors.

1989 • 53 citations

Does cholecystokinin potentiate dopamine action in the nucleus accumbens?

1986 • 53 citations

Characterization of the locomotor depression produced by an A₂‐selective adenosine agonist

1990 • 52 citations

Glycosylation of the mammalian alpha 1-adrenergic receptor by complex type N-linked oligosaccharides.

1987 • 51 citations

Dissociation of the locomotor and hypotensive effects of adenosine analogues in the rat

1984 • 51 citations

Activation of 5-hydroxytryptamine1A receptors increases the affinity of galanin receptors in di- and telencephalic areas of the rat

1991 • 50 citations

Behavioral effects of intrastriatal caffeine mediated by adenosinergic modulation of dopamine

1991 • 50 citations

Multiple actions of substance P that regulate the functional properties of acetylcholine receptors of clonal rat PC12 cells.

1987 • 50 citations

Phosphorylation and assembly of nicotinic acetylcholine receptor subunits in cultured chick muscle cells.

1987 • 49 citations

Structure‐activity relationships for transmembrane signaling: the receptor's turn

1991 • 48 citations

Actions of Neurotensin: A Review of the Electrophysiological Studiesa

1992 • 48 citations

Polyamines, Ornithine Decarboxylase, and Diamine Oxidase in the Substantia Nigra and Striatum of the Male Rat After Hemitransection

1988 • 47 citations

Biochemical characterization of the intramembrane interaction between neurotensin and dopamine D2 receptors in the rat brain

1991 • 47 citations

Aspects of the structure of the D2 dopamine receptor

1990 • 47 citations

Reciprocal interactions between α2-adrenoceptor agonist and neuropeptide Y binding sites in the nucleus tractus solitarius of the rat

1989 • 47 citations

Receptor-Receptor Interactions

1987 • 46 citations

Neurotensin Binding to Dopamine

1990 • 45 citations

Dopamine and neurotensin storage in colocalized and noncolocalized neuronal populations.

1989 • 45 citations

The effects of neurotensin and [D-Tyr11]-NT on the hyperactivity induced by intra-accumbens administration of a potent dopamine receptor agonist

1985 • 45 citations

Evidence for Cholecystokinin‐Dopamine Receptor Interactions in the Central Nervous System of the Adult and Old Rat

1985 • 44 citations

Monoamine synthesis and caffeine-induced locomotor activity

1978 • 44 citations

Centrally injected neuropeptide Y (13–36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1–36) in the awake male rat

1990 • 41 citations

Purification, characterization, and amino-terminal sequence of rat ovarian receptor for luteinizing hormone/human choriogonadotropin

1989 • 41 citations

Effects of adenosine on autonomic control of heart rate in man

1987 • 40 citations

Microinjection of cholecystokinin into the rat ventral tegmental area potentiates dopamine‐induced hypolocomotion

1989 • 40 citations

Effects of adult or neonatal treatment with 6-hydroxydopamine or 5,7-dihydroxytryptamine on locomotor activity, monoamine levels, and response to caffeine

1986 • 40 citations

Aspects of neural plasticity in the central nervous system—VII. Theoretical aspects of brain communication and computation☆

1990 • 39 citations

Rotational behaviour elicited by intracerebral injections of apomorphine and pergolide in 6‐hydroxy‐dopamine‐lesioned rats. I: Comparison between systemic and intrastriatal injections

1985 • 38 citations

Intraventricular injection of neurotensin reduces dopamine D2 agonist binding in rat forebrain and intermediate lobe of the pituitary gland. Relationship to serum hormone levels and nerve terminal coexistence

1990 • 37 citations

Behavioral effects of adenosine analogs in squirrel monkeys: relation to adenosine A2 receptors

1986 • 37 citations

Modulation by vasoactive intestinal peptide (VIP) of serotonin receptors in membranes from rat hippocampus

1983 • 37 citations

Methylxanthine effects on caudate dopamine release as measured by electrochemistry

1989 • 36 citations

Further evidence for the existence of interactions between receptors for dopamine and neurotensin. Dopamine reduces the affinity and increases the number of [³H]‐neurotensin binding sites in the subcortical limbic forebrain of the rat

1985 • 36 citations

D1 and D2 dopamine receptor regulation of striatonigral and striatopallidal neurons

1992 • 36 citations

Effects of (+)-HA-966 and 7-chlorokynurenic acid on the kinetics of N-methyl-D-aspartate receptor agonist responses in rat cultured cortical neurons.

1991 • 35 citations

NECA-induced hypomotility in mice: Evidence for a predominantly central site of action

1989 • 35 citations

G proteins in cellular control

1992 • 34 citations

Centrally coinjected galanin and a 5-HT1A agonist act synergistically to produce vasodepressor responses in the rat

1991 • 33 citations

Pertussis toxin treatment counteracts intramembrane interactions between neuropeptide Y receptors and α2-adrenoceptors

1989 • 31 citations

Neurotensin reduces the affinity of dopamine D2 receptors in membranes from post mortem human caudate-putamen

1990 • 31 citations

Endogenous Ligands for High-Affinity Recognition sites of Psychotropic Drugs

1988 • 31 citations

Subcortical limbic 3H-N-propylnorapomorphine binding sites are markedly modulated by cholecystokinin-8 in vitro

1983 • 31 citations

Phosphorylation of the porcine atrial muscarinic acetylcholine receptor by cyclic AMP-dependent protein kinase

1987 • 30 citations

Neurotensin and cholecystokinin octapeptide control synergistically dopamine release and dopamine D2 receptor affinity in rat neostriatum

1993 • 30 citations

The Mammalian β-Adrenergic Receptor: Structural and Functional Characterization of the Carbohydrate Moiety

1987 • 30 citations

The neuropeptide cholecystokinin (CCK)

1990 • 29 citations

Nicotinic receptor-associated 43K protein and progressive stabilization of the postsynaptic membrane

1992 • 29 citations

l-glutamate reduces the affinity of [3H]N-propylnorapomorphine binding sites in striatal membranes

1984 • 29 citations

A novel substance P binding site in bovine adrenal medulla

1990 • 27 citations

Phosphorylation by Cyclic AMP‐Dependent Protein Kinase Modulates Agonist Binding to the D₂ Dopamine Receptor

1991 • 27 citations

Dopaminergic regulation of cholecystokinin mRNA content in rat striatum

1992 • 27 citations

Modulation by vasoactive intestinal peptide of serotonin1 receptors in the dorsal hippocampus of the rat brain: An autoradiographic study

1983 • 27 citations

N-linked oligosaccharides are responsible for rat striatal dopamine D2 receptor heterogeneity

1989 • 25 citations

Postnatal ontogeny of cells expressing prepro‐neurotensin/neuromedin N mRNA in the rat forebrain and midbrain: A hybridization histochemical study involving isotope‐labeled and enzyme‐labeled probes

1991 • 24 citations

Receptor-receptor interactions : a new intramembrane integrative mechanism : proceedings of an international symposium held at the Wenner-Gren Center, Stockholm, October 9th-11th, 1986

1987 • 23 citations

Neuropeptide Y/angiotensin II interactions in central cardiovascular regulation of the rat

1991 • 23 citations

Neuropeptides, excitatory amino acid and adenosine A2 receptors regulate D2 receptors via intramembrane receptor-receptor interactions. Relevance for Parkinson's disease and schizophrenia

1992 • 22 citations

Modulation of Dopamine D1 and D2 Transmission Lines in the Central Nervous System

1990 • 22 citations

The C-terminal neurotensin-(8–13) fragment potently modulates rat neostriatal dopamine D2 receptors

1993 • 19 citations

Effects of polyamine synthesis blockade on neuronal loss and astroglial reaction after transient forebrain ischemia

1993 • 19 citations

Kicking Chaos out of Lasers

1992 • 19 citations

Evidence for interactions between striatal cholecystokinin and glutamate receptors. CCK‐8 in vitro produces a marked downregulation of ³H‐glutamate binding sites in striatal membranes

1983 • 18 citations

Involvement of cholecystokinin receptors in the control of striatal dopamine autoreceptors

1990 • 17 citations

Adenosine A_2a receptor expression in striatal neurons: Implications for basal ganglia pathophysiology

1993 • 17 citations

Modulation of dopamine D1 receptor binding by neurotensin in the rat striatum

1989 • 16 citations

Effects of selected analogs of adenosine on schedule-controlled behavior in rats

1986 • 16 citations

beta-Adrenergic receptor isolation and characterization with immobilized drugs and monoclonal antibodies.

1983 • 15 citations

Studies of neurotensin‐dopamine receptor interactions in striatal membranes of the male rat. The influence of 6‐hydroxydopamine‐induced dopamine receptor supersensitivity

1986 • 14 citations

Aspects on the Integrative Capabilities of the Central Nervous System: Evidence for ‘Volume Transmission’ and its Possible Relevance for Receptor-Receptor Interactions

1987 • 14 citations

Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes

1993 • 12 citations

Angiotensin II reduces the affinity of [³H]para‐aminoclonidine binding sites in membrane preparations from the rat dorsomedial medulla oblongata

1988 • 11 citations

Effect of atrial natriuretic factor (ANF) on nicotinic acetylcholine receptor channels in bovine chromaffin cells

1989 • 10 citations

Possible Involvement of Pertussis Toxin‐Sensitive G Proteins and D₂ Dopamine Receptors in the A₁ Adenosine Receptor‐Adenylate Cyclase System in Rat Cerebral Cortex

1990 • 7 citations

Aspects on the Integrative Capabilities of the Central Nervous System: Evidence for ‘Volume Transmission’ and its Possible Relevance for Receptor-Receptor Interactions

1987 • 7 citations

Neurotensin Stimulates the Phosphorylation of Caudate Nucleus Synaptosomal Proteinsa

1988 • 7 citations

Glycoprotein nature of α₂‐adrenergic receptors labeled with p‐azido[³H] clonidine in calf retina membranes

1988 • 5 citations

Evidence for interactions between [3H]glutamate and [3H]kainic acid binding sites in rat striatal membranes. Possible relevance for kainic acid neurotoxicity

1983 • 5 citations

Diversity in receptor signalling: cellular individuality and the search for selective drugs

1991 • 4 citations

Coactivation of dopamine D1 and D2 receptors increases the affinity of cholecystokinin-8 receptors in membranes from post-mortem human caudate-putamen

1992 • 3 citations

Receptor Mediated Activation of Phospholipase A2: Arachidonic Acid and its Metabolites as Second Messengers

1987 • 2 citations

Receptor Mediated Activation of Phospholipase A2: Arachidonic Acid and its Metabolites as Second Messengers

1987 • 1 citations

Deleted Work

1955 • 0 citations