Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications
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Abstract
References (409)
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Bromocriptine in Parkinsonism
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Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas
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Tolerance phenomena with neuroleptics catalepsy, apomorphine stereotypies and striatal dopamine metabolism in the rat after single and repeated administration of loxapine and haloperidol
1973 • 256 citations
Dopamine D-1 receptor agonists combined with the selective D-2 agonist quinpirole facilitate the expression of oral stereotyped behaviour in rats
1987 • 255 citations
Pharmacological characterization of the D2 dopamine receptor negatively coupled with adenylate cyclase in rat anterior pituitary.
1983 • 254 citations
Association with persistent neuroleptic-induced dyskinesia of regional changes in brain GABA synthesis
1984 • 252 citations
Dopamine receptors in brain and periphery
1987 • 251 citations
Induction of oral dyskinesias in naive rats by D1 stimulation
1983 • 250 citations
The D-1 dopamine receptor antagonist SCH 23390 also interacts potently with brain serotonin (5-HT2) receptors
1986 • 245 citations
The Action of Neuroleptic Drugs on Dopamine-Stimulated Adenosine Cyclic 3',5'-Monophosphate Production in Rat Neostriatum and Limbic Forebrain
1974 • 240 citations
Pharmacological Specificity of Conditioned Avoidance Response Inhibition in Rats: Inhibition by Neuroleptics and Correlation to Dopamine Receptor Blockade
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Characterization of dopamine receptors mediating inhibition of adenylate cyclase activity in rat striatum.
1985 • 236 citations
Minireview A systematic study of the pharmacological activities of dopamine antagonists
1979 • 232 citations
3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors
1981 • 229 citations
Schizophrenic Symptoms Improve with Apomorphine
1978 • 228 citations
Dopamine-Sensitive Adenylate Cyclase: Location in Substantia Nigra
1977 • 227 citations
Dopaminergic innervation of the globus pallidus by collaterals from the nigrostriatal pathway
1979 • 222 citations
Acute dystonia induced by neuroleptic drugs
1986 • 220 citations
Pharmacological characterization of dopamine autoreceptors in the rat ventral tegmental area: microiontophoretic studies.
1984 • 220 citations
Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat
1983 • 212 citations
Differential regional development of tolerance to increase in dopamine turnover upon repeated neuroleptic administration
1977 • 212 citations
Dopamine-receptor agonists: Mechanisms underlying autoreceptor selectivity
1985 • 209 citations
Neurobiological substrates of tardive dyskinesia: the GABA hypothesis
1984 • 209 citations
Apomorphine in Parkinson's disease.
1951 • 208 citations
Selective blockade of dopamine D-1 receptors by SCH 23390 discloses striatal dopamine D-2 receptors mediating the inhibition of adenylate cyclase in rats
1984 • 207 citations
Intravenous self-administration of dopamine receptor agonists by rhesus monkeys.
1984 • 203 citations
Dopamine receptors: Pharmacological and anatomical evidences indicate that two distinct dopamine receptor populations are present in rat striatum
1978 • 203 citations
Behavioural stimulation is induced by separate dopamine D-1 and D-2 receptor sites in reserpine-pretreated but not in normal rats
1985 • 202 citations
6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.
1987 • 201 citations
Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP
1983 • 200 citations
Subcellular localization of dopamine-sensitive adenylate cyclase and dopamine receptor binding activities
1978 • 198 citations
Dopaminergic mechanisms and motor function: Characterization of D-1 and D-2 dopamine receptor interactions
1986 • 198 citations
Lisuride and Other Dopamine Agonists
1983 • 198 citations
Three classes of dopamine receptor (D-2, D-3, D-4) identified by binding studies with 3H-apomorphine and 3H-domperidone
1980 • 197 citations
Stimulation of both D1 and D2 dopamine receptors appears necessary for full expression of postsynaptic effects of dopamine agonists: a neurophysiological study
1987 • 193 citations
Electrophysiological evidence for the existence of both D-1 and D-2 dopamine receptors in the rat nucleus accumbens
1986 • 193 citations
Parametric analysis of brain stimulation reward in the rat: III. Effect of performance variables on the reward summation function.
1974 • 192 citations
Activation of dopamine receptors inhibits calcium-dependent glutamate release from cotico-striatal terminals in vitro
1980 • 189 citations
Behavioral correlations of dopamine receptor activation
1983 • 188 citations
Independent in vitro regulation by the D-2 dopamine receptor of dopamine-stimulated efflux of cyclic AMP and K+-stimulated release of acetylcholine from rat neostriatum
1982 • 184 citations
Selective stimulation of dopamine and noradrenaline autoreceptors by B-HT 920 and B-HT 933, respectively
1982 • 182 citations
Effects of the putative D-1 antagonist SCH 23390 on stereotyped behaviour induced by the D-2 agonist RU24213
1985 • 179 citations
Synergistic effects of D1 and D2 dopamine agonists on turning behaviour in rats
1986 • 178 citations
Catecholamines and self-stimulation: Reward and performance effects dissociated
1978 • 175 citations
Blockade of D-1 receptors by SCH 23390 antagonizes morphine- and amphetamine-induced place preference conditioning
1987 • 169 citations
Modulation of striatal [3H]-glutamic acid release by dopaminergic drugs
1980 • 169 citations
Quantitative autoradiography of dopamine D2 sites in rat caudate-putamen: Localization to intrinsic neurons and not to neocortical afferents
1987 • 165 citations
d-Amphetamine-induced depression of central dopamine neurons: Evidence for mediation by both autoreceptors and a striato-nigral feedback pathway
1978 • 165 citations
The yawning-penile erection syndrome as a model for putative dopamine autoreceptor activity
1984 • 163 citations
Nucleus accumbens to globus pallidus GABA projection subserving ambulatory activity
1980 • 162 citations
Changes in dopamine-mediated behaviour during one year's neuroleptic administration
1979 • 160 citations
Modulation by endogenous dopamine of the release of acetylcholine in the caudate nucleus of the rabbit
1980 • 159 citations
Dopamine receptor of the porcine anterior pituitary gland. Evidence for two affinity states discriminated by both agonists and antagonists.
1982 • 158 citations
SCH-23390: A selective D1 dopamine antagonist with potent D2 behavioral actions
1984 • 158 citations
Sniffing, rearing and locomotor responses to the D-1 dopamine agonist R-SK&F 38393 and to apomorphine: Differential interactions with the selective D-1 and D-2 antagonists SCH 23390 and metoclopramide
1985 • 158 citations
Dopamine Modulation of the Effects of γ-Aminobutyric Acid on Substantia Nigra Pars Reticulata Neurons
1983 • 158 citations
Presence of substance P and GABA in separate striatonigral neurons
1977 • 157 citations
Effects of D1 and D2 dopamine receptor stimulation on the activity of substantia nigra pars reticulata neurons in 6-hydroxydopamine lesioned rats: D1/D2 coactivation induces potentiated responses
1987 • 155 citations
Differential inhibition by dopamine D-1 and D-2 antagonists of circling behaviour induced by dopamine agonists in rats with unilateral 6-hydroxydopamine lesions
1984 • 153 citations
An analysis of chlorpromazine-induced suppression of the avoidance response
1962 • 153 citations
d -Amphetamine-Induced Inhibition of Central Dopaminergic Neurons: Mediation by a Striato-Nigral Feedback Pathway
1976 • 153 citations
Differential involvement of dopamine D-1 and D-2 receptors in the circling behaviour induced by apomorphine, SK & F 38393, pergolide and LY 171555 in 6-hydroxydopamine-lesioned rats
1985 • 152 citations
In vivo release of [3H]γ-aminobutyric acid in the rat neostriatum—II. Opposing effects of D1 and D2 dopamine receptor stimulation in the dorsal caudate putamen
1986 • 150 citations
Catalepsy induced by SCH 23390 in rats
1985 • 148 citations
Essays in neurochemistry and neuropharmacology
1979 • 148 citations
Localization of Nigral Dopamine-Sensitive Adenylate Cyclase on Neurons Originating from the Corpus Striatum
1977 • 147 citations
D2-dopamine receptor-mediated inhibition of cyclic AMP formation in striatal neurons in primary culture.
1985 • 143 citations
Hyperpolarizing and depolarizing actions of dopamine via D-1 and D-2 receptors on nucleus accumbens neurons
1986 • 143 citations
Dopamine agonist-induced locomotor activity in rats treated with 6-hydroxydopamine at differing ages: functional supersensitivity of D-1 dopamine receptors in neonatally lesioned rats.
1985 • 143 citations
Stimulation of D2-dopamine receptors in rat neostriatum inhibits the release of acetylcholine and dopamine but does not affect the release of γ-aminobutyric acid, glutamate or serotonin
1982 • 142 citations
A comparison between dopamine-stimulated adenylate cyclase and 3H-SCH 23390 binding in rat striatum
1985 • 141 citations
Behavioural correlates of the action of selective D-1 dopamine receptor antagonists
1986 • 141 citations
Further evidence for the involvement of D2, but not D1 dopamine receptors in dopaminergic control of striatal cholinergic transmission
1982 • 141 citations
The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein.
1987 • 140 citations
Evidence that D-1 dopamine receptors contribute to the supersensitive behavioral responses induced by L-dihydroxyphenylalanine in rats treated neonatally with 6-hydroxydopamine.
1985 • 140 citations
Reduction of nigral glutamic acid decarboxylase in rats with neuroleptic-induced oral dyskinesia
1983 • 140 citations
Dopaminergic Mechanisms in the Teleost Retina
1981 • 140 citations
Selective dopamine D2 receptor reduction enhances A D1 mediated oral dyskinesia in rats
1986 • 138 citations
Differential effects of dopamine D1 and D2 agonists and antagonists on velocity of movement, rearing and grooming in the mouse
1986 • 138 citations
The electrophysiology of dopamine (D2) receptors: A study of the actions of dopamine on corticostriatal transmission
1983 • 137 citations
Selective D-1 dopamine receptor agonist treatment of parkinson's disease
1987 • 136 citations
Behavioral and radioligand binding evidence for irreversible dopamine receptor blockade by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
1983 • 135 citations
D-1 dopamine receptor stimulation enables the inhibition of nucleus accumbens neurons by a D-2 receptor agonist
1987 • 134 citations
Opposite effects of a D1 and a D2 agonist on oral movements in rats
1987 • 134 citations
Relationship between receptor occupancy and response at striatal dopamine autoreceptors.
1987 • 133 citations
Dopamine receptor agonists: Mechanisms underlying autoreceptor selectivity II. Theoretical considerations
1985 • 131 citations
Effects of chronic SCH23390 treatment on the biochemical and behavioral properties of D1 and D2 dopamine receptors: potentiated behavioral responses to a D2 dopamine agonist after selective D1 dopamine receptor upregulation.
1986 • 131 citations
Stereotyped behaviour in response to the selective D-2 dopamine receptor agonist RU 24213 is enhanced by pretreatment with the selective D-1 agonist SK&F 38393
1986 • 130 citations
Dopamine receptor agonists: Intrinsic activity vs. state of receptor
1983 • 127 citations
Interaction of pergolide with central dopaminergic receptors.
1980 • 126 citations
Peripheral pre- and post-synaptic dopamine receptors: are they different from dopamine receptors in the central nervous system?
1979 • 125 citations
Diastolic properties of the hypertrophied left ventricle in spontaneously hypertensive rats
1983 • 125 citations
Selective D-1 dopamine receptor increase following chronic treatment with SCH 23390
1985 • 125 citations
Inactivation of D1 and D2 dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: selective protection by neuroleptics.
1985 • 125 citations
Dopaminergic inhibition of adenylate cyclase correlates with high affinity agonist binding to anterior pituitary D2 dopamine receptors
1984 • 125 citations
Activity of two new potent dopaminergic agonists at the striatal and anterior pituitary levels
1980 • 122 citations
Functional evidence for selective dopamine D-1 receptor blockade by SCH 23390
1984 • 121 citations
Resolution and absolute configuration of an ergoline-related dopamine agonist, trans-4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H(or 2H)-pyrazolo[3,4-g]quinoline
1983 • 121 citations
Bromocriptine induces marked locomotor stimulation in dopamine-depleted mice when D-1 dopamine receptors are stimulated with SKF38393
1986 • 121 citations
Further functional in vitro comparison of pre- and postsynaptic dopamine receptors in the rabbit caudate nucleus
1983 • 121 citations
Effects of lisuride and LSD on cerebral monoamine systems and hallucinosis
1978 • 120 citations
Peripheral dopamine receptors: A classification based on potency series and specific antagonism
1983 • 120 citations
Binding of [3H]SCH23390 in Rat Brain: Regional Distribution and Effects of Assay Conditions and GTP Suggest Interactions at a D1‐Like Dopamine Receptor
1985 • 116 citations
Loss of rat striatal dopamine receptors with ageing is selective for D-2 but not D-1 sites: Association with increased non-specific binding of the D-1 ligand [3H]piflutixol
1984 • 115 citations
Dopamine enhances terminal excitability of hippocampal-accumbens neurons via D2 receptor: role of dopamine in presynaptic inhibition
1986 • 115 citations
Guanine nucleotide regulation of agonist interactions at [3H]SCH23390-labeled D1 dopamine receptors in rat striatum
1986 • 115 citations
Extrapyramidal and mesolimbic involvement with the stereotypic activity of D- and L-amphetamine
1974 • 114 citations
The dopamine D2 agonist LY 141865, but not the D1 agonist SKF 38393, reverses parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset
1985 • 113 citations
Antipsychotic drug effects on the electrical activity of dopaminergic neurons
1984 • 112 citations
Dopamine autoreceptors: pharmacology, function and comparison with post-synaptic dopamine receptors.
1979 • 111 citations
Neonatal-6-hydroxydopamine treatment: Model of susceptibility for self-mutilation in the lesch-nyhan syndrome
1984 • 107 citations
Effect of dopamine D-1 and D-2 receptor selective drugs on dopamine release and metabolism in rat striatum in vivo
1986 • 106 citations
5HT-receptor antagonist properties of SCH 23390 in vascular smooth muscle and brain
1984 • 105 citations
Peripheral dopamine receptors, potential targets for a new class of antihypertensive agents
1982 • 105 citations
Selective D2 dopamine receptor agonists prevent catalepsy induced by SCH 23390, a selective D1 antagonist
1985 • 105 citations
Evidence for Different States of the Dopamine Dl Receptor: Clozapine and Fluperlapine May Preferentially Label an Adenylate Cyclase‐Coupled State of the Dl Receptor
1986 • 104 citations
Antagonism of the amphetamine cue by both classical and atypical antipsychotic drugs
1985 • 103 citations
Picomolar affinity of 125I-SCH 23982 for D1 receptors in brain demonstrated with digital subtraction autoradiography
1987 • 103 citations
Selective binding of YM-09151-2, a new potent neuroleptic, to D2-dopaminergic receptors.
1983 • 103 citations
Dopaminergic stimulation of cyclic AMP accumulation and parathyroid hormone release from dispersed bovine parathyroid cells
1977 • 102 citations
Localization of D-2 dopamine receptors to intrinsic striatal neurones by quantitative autoradiography
1986 • 102 citations
Behavioural and pharmacological characterization of the mouth movements induced by muscarinic agonists in the rat
1986 • 102 citations
SCH-23390 antagonism of a D-2 dopamine agonist depends upon catecholaminergic neurons
1985 • 102 citations
Physiological Concentrations of Dopamine Decrease Adenosine 3′,5′-Monophosphate Levels in Cultured Rat Anterior Pituitary Cells and Enriched Populations of Lactotrophs: Evidence for a Causal Relationship to Inhibition of Prolactin Release*
1982 • 101 citations
Characterisation of the mechanisms by which purported dopamine agonists reduce spontaneous locomotor activity of mice
1981 • 100 citations
Coupling of Dopamine D 1 Recognition Sites with Adenylate Cyclase in Nuclei Accumbens and Caudatus of Schizophrenics
1983 • 99 citations
Some atypical neuroleptics inhibit [3H]SCH 23390 binding in vivo
1986 • 98 citations
Similarities between the binding of 3H-piflutixol and 3H-flupentixol to rat striatal dopamine receptors in vitro
1981 • 98 citations
Locomotor behaviors in response to new selective D-1 and D-2 dopamine receptor agonists, and the influence of selective antagonists
1986 • 97 citations
Dopamine and [D-ALA2, D-Leu5]enkephalin inhibit the electrically stimulated neurohypophyseal release of vasopressin in vitro: evidence for calcium-dependent opiate action
1982 • 96 citations
[3H]SCH 23390 binding sites increase after chronic blockade of D-1 dopamine receptors
1985 • 96 citations
Hyperactivity induced by stimulation of separate dopamine D-1 and D-2 receptors in rats with bilateral 6-OHDA lesions
1985 • 95 citations
Detection of dopamine receptors in the area postrema
1981 • 95 citations
Inhibition of inositol phospholipid breakdown by D2 dopamine receptors in dissociated bovine anterior pituitary cells
1985 • 95 citations
3H-SCH 23390 binding sites in the rat substantia nigra: Evidence for a presynaptic localization and innervation by dopamine
1986 • 93 citations
Interactions of novel dopaminergic ligands with D-1 and D-2 dopamine receptors
1982 • 93 citations
The D1 dopamine receptor antagonist, SCH 23390 reduces locomotor activity and rearing in rats
1985 • 93 citations
Permissive role of D-1 receptor stimulation by endogenous dopamine for the expression of postsynaptic D-2-mediated behavioural responses. Yawning in rats
1987 • 92 citations
Selective and stereospecific interactions of R-SK&F 38393 with [3H]piflutixol but not [3H]spiperone binding to striatal D1 and D2 dopamine receptors: Comparisons with SCH 23390
1984 • 92 citations
Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers
1983 • 90 citations
Stimulation of a D-2 Dopamine Receptor in the Intermediate Lobe of the Rat Pituitary Gland Decreases the Responsiveness of the β-Adrenoceptor: Biochemical Mechanism
1981 • 88 citations
Separation of peripheral dopamine receptors by a selective DA1 antagonist, SCH 23390.
1984 • 86 citations
Pallidal and entopeduncular intracellular responses to striatal, cortical, thalamic, and sensory inputs
1974 • 86 citations
Bromocriptine in Parkinsonism: long-term treatment, dose response, and comparison with levodopa.
1976 • 85 citations
Antistereotypic effects of dopamine D-1 and D-2 antagonists after intrastriatal injection in rats. pharmacological and regional specificity
1985 • 85 citations
In vitro acetylcholine release from rat caudate nucleus as a new model for testing drugs with dopamine-receptor activity
1979 • 84 citations
Further evidence that 3H-cis(Z)flupenthixol binds to the adenylate cyclase-associated dopamine receptor (D-1) in rat corpus striatum
1980 • 84 citations
Neuropharmacology of Central Nervous System and Behavioral Disorders
1982 • 83 citations
Chronic neuroleptic treatment increases D-2 but not D-1 receptors in rat striatum
1985 • 83 citations
D-1 and D-2 dopamine receptor blockade: interactive effects in vitro and in vivo.
1986 • 83 citations
Effects of dopamine on spontaneous and evoked activity of caudate neurons
1983 • 82 citations
Intracellular studies of the corpus striatum II. Patterns of synaptic activities in lenticular and entopeduncular neurons
1967 • 81 citations
Reduction of the rewarding effect of brain stimulation by a blockade of dopamine D1 receptor with SCH 23390
1986 • 80 citations
Role of presynaptic dopamine receptors in regulation of the glutamatergic neurotransmission in rat neostriatum
1984 • 79 citations
In vivo release of [3H]γ-aminobutyric acid in the rat neostriatum—I. Characterization and topographical heterogeneity of the effects of dopaminergic and cholinergic agents
1986 • 78 citations
Dopamine, acting through D-2 receptors, inhibits rat striatal adenylate cyclase by a GTP-dependent process.
1986 • 78 citations
Opposing effects of D-1 and D-2 receptor antagonists on acetylcholine levels in the rat striatum
1986 • 78 citations
D-2 Dopamine Receptor-Mediated Inhibition of Adenylate Cyclase Activity in the Intermediate Lobe of the Rat Pituitary Gland Requires Guanosine 5'-Triphosphate
1982 • 78 citations
Sedation and sleep induced by high doses of apomorphine after blockade of D-1 receptors by SCH 23390
1985 • 77 citations
Dual action on central dopamine function of transdihydrolisuride, a 9, 10-dihydrogenated analogue of the ergot dopamine agonist lisuride
1983 • 76 citations
Studies on renal dopamine receptors with a new agonist
1978 • 73 citations
Endogenous dopamine can modulate inhibition of substantia nigra pars reticulata neurons elicited by GABA iontophoresis or striatal stimulation
1986 • 73 citations
Analysis of dopamine d1 and d2 receptor involvement in d- and l-amphetamine-induced anorexia in rats
1985 • 72 citations
[125I]SCH 23982: the ligand of choice for identifying the D-1 dopamine receptor
1986 • 71 citations
Dopaminergic modulation of evoked vasopressin release from the isolated neurohypophysis of the rat
1982 • 71 citations
Biochemical Identification of the β-Adrenoceptor and Evidence for the Involvement of an Adenosine 3′,5′-Monophosphate System in the β-Adrenergically Induced Release of a-Melanocyte-Stimulating Hormone in the Intermediate Lobe of the Rat Pituitary Gland
1980 • 71 citations
The dopaminergic innervation of the intermediate lobe and of the neural lobe of the pituitary gland.
1985 • 71 citations
Adrenergic Effect of Chronic Administration of Neuroleptics
1967 • 70 citations
Dopamine D2 receptors and dopamine metabolismRelationship between biochemical and behavioural effects of substituted benzamide drugs
1986 • 70 citations
Dopamine attenuates the effects of GABA on single unit activity in the Globus pallidus
1984 • 69 citations
Neurotransmitter interactions related to central dopamine neurons.
1978 • 69 citations
Agonist high- and low-affinity states of the D2-dopamine receptor in calf brain. Partial conversion by guanine nucleotide.
1984 • 68 citations
Behavioral Actions of Neuroleptics
1978 • 68 citations
Interactions of dopamine agonists with brain D1 receptors labeled by 3H-antagonists. Evidence for the presence of high and low affinity agonist-binding states.
1985 • 68 citations
Failure of SKF 38393‐A to relieve parkinsonian symptoms induced by 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine in the marmoset
1985 • 67 citations
N,N-disubstituted 2-aminotetralins are potent D-2 dopamine receptor agonists
1984 • 67 citations
Presynaptic dopaminergic control of high affinity glutamate uptake in the striatum
1983 • 67 citations
Neurophysiological evidence that D-1 dopamine receptor blockade attenuates postsynaptic but not autoreceptor-mediated effects of dopamine agonists
1986 • 67 citations
Preferential inhibition of ligand binding to calf striatal dopamine D1 receptors by SCH 23390
1983 • 66 citations
Dopamine receptor subtypes: In vivo biochemical evidence for functional interaction
1985 • 66 citations
An iodinated ligand identifying the D-1 dopamine receptor
1985 • 65 citations
D-2 receptor stimulation inhibits cyclic AMP formation brought about by D-1 receptor stimulation in rat neostriatum but not nucleus accumbens
1986 • 65 citations
Excitatory input from sensory motor cortex to neostriatum and its modification by conditioning stimulation of the substantia nigra
1984 • 63 citations
Dopamine autoreceptors and the effects of drugs on locomotion and dopamine synthesis
1985 • 63 citations
Non-specific supersensitivity of striatal dopamine receptors after 6-hydroxydopamine lesion of the nigrostriatal pathway
1976 • 62 citations
The dopamine receptor in the intermediate lobe of the rat pituitary gland is negatively coupled to adenylate cyclase
1982 • 62 citations
Lisuride versus bromocriptine treatment in Parkinson disease
1982 • 61 citations
Antagonism of apomorphine-induced yawning by SCH 23390: Evidence against the autoreceptor hypothesis
1986 • 59 citations
Neuroleptic-induced acute dyskinesias in squirrel monkeys: Correlation with propensity to cause extrapyramidal side effects
1980 • 58 citations
Regulation of phosphorylation of proteins I, IIIa, and IIIb in rat neurohypophysis in vitro by electrical stimulation and by neuroactive agents.
1982 • 58 citations
Distinct target size of dopamine D-1 and D-2 receptors in rat striatum
1984 • 58 citations
Involvement of septal and striatal dopamine D-2 receptors in yawning behavior in rats
1986 • 57 citations
Quantitative autoradiographic localization of D-1 dopamine receptors in the rat brain: Use of the iodinated ligand [125I]SCH 23982
1986 • 56 citations
Thienopyridine derivatives identified as the first selective, full efficacy, dopamine D1 receptor agonists
1987 • 56 citations
Handbook of psychiatry and endocrinology
1983 • 55 citations
Specific binding of 3H-SCH 23390 to dopamine D1 receptors
1986 • 55 citations
[3H]SCH23390 has the characteristics of a dopamine receptor ligand in the rat central nervous system
1984 • 55 citations
Effect of the dopamine D-1 antagonist SCH 23390 on rotational behaviour induced by apomorphine and pergolide in 6-hydroxy-dopamine denervated rats
1985 • 55 citations
Synthesis, resolution, absolute stereochemistry, and enantioselectivity of 3',4'-dihydroxynomifensine
1984 • 54 citations
SCH 23390 and SK&F 83566 are antagonists at vascular dopamine and serotonin receptors
1985 • 54 citations
Dystonia in Untreated Parkinsonism
1986 • 54 citations
Characterization of the Dopamine-Responsive Adenylate Cyclase of Bovine Parathyroid Cells and Its Relationship to Parathyroid Hormone Secretion
1980 • 53 citations
PHARMACOLOGICAL EVIDENCE FOR THE SUBCLASSIFICATION OF CENTRAL DOPAMINE RECEPTORS IN THE RAT
1982 • 53 citations
Yawning is elicited by D2 dopamine agonists but is blocked by the D1 antagonist, SCH 23390
1987 • 53 citations
Pharmacologic evidence for direct dopaminergic regulation of striatal acetylcholine release
1986 • 53 citations
Involvement of the D-2 dopamine receptor in the neuroleptic-induced decrease in nigral substance P
1984 • 52 citations
Peripheral dopamine receptor subtypes — a closer look
1985 • 51 citations
Topography of dopamine behaviours mediated by D1 and D2 receptors revealed by intrastriatal injection of SKF 38393, lisuride and apomorphine in rats with a unilateral 6-hydroxydopamine-induced lesion
1987 • 50 citations
Kainate lesion dissociates striatal dopamine receptor radioligand binding sites
1981 • 50 citations
Stimulation of pre- and postsynaptic dopamine receptors by an ergoline and by a partial ergoline
1981 • 50 citations
Presynaptic regulation of tyrosine hydroxylase activity in rat striatal synaptosomes by dopamine analogs.
1980 • 49 citations
Postsynaptic dopamine agonistic effects of 3-PPP enantiomers revealed by bilateral 6-hydroxy-dopamine lesions and by chronic reserpine treatment in rats
1984 • 49 citations
An electrophysiological analysis of the actions of the 3-PPP enantiomers on the nigrostriatal dopamine system
1985 • 49 citations
Role of nigral dopamine in amphetamine-induced locomotor activity
1983 • 48 citations
SCH 23390 blocks D-1 and D-2 dopamine receptors in rat neostriatum in vitro
1984 • 48 citations
Effects of dopamine depletion on rotational behavior to dopamine agonists
1983 • 48 citations
The effects of SCH 23390, YM 09151-2, (+)- and (−)-3-PPP and some classical neuroleptics on D-1 and D-2 receptors in rat neostriatum in vitro
1984 • 48 citations
Sensorimotor impairment and elevated levels of dopamine metabolites in the neostriatum occur rapidly after intranigral injection of 6-hydroxydopamine or gamma-hydroxybutyrate in awake rats
1984 • 47 citations
SCH 23390, a selective dopamine D1 antagonist, activates dopamine neurons but fails to prevent their inhibition by apomorphine
1985 • 47 citations
Opposite responses in the striato-nigral substance P system to D1 and D2 receptor activation
1984 • 47 citations
Dopamine D-2 receptors inhibit D-1 stimulated cyclic AMP accumulation in striatum but not limbic forebrain
1987 • 47 citations
Autoradiographic localization of D1 dopamine receptors in the rat brain with [3H]SKF 38393
1985 • 47 citations
SCH 23390 dissociated from conventional neuroleptics in apomorphine climbing and primate acute dyskinesia models
1985 • 46 citations
Differential effects of selective and non-selective neuroleptics on intracellular and extracellular cyclic AMP accumulation in rat striatal slices
1985 • 46 citations
Specific Inhibition of Dopamine D‐1‐Mediated Cyclic AMP Formation by Dopamine D‐2, Muscarinic Cholinergic, and Opiate Receptor Stimulation in Rat Striatal Slices
1986 • 46 citations
SCH23390 effects on apomorphine-induced responses of nigral dopaminergic neurons.
1986 • 46 citations
Comparison of the CNS effects induced by TRH and bicuculline after microinjection into medial septum, substantia nigra and inferior colliculus: Absence of support for a GABA antagonist action for TRH
1984 • 46 citations
The putative dopamine autoreceptor agonist B-HT 920 decreases nigral dopamine cell firing rate and prolactin release in rat
1985 • 45 citations
Sedative, hypnotic, and antipsychotic effects of low doses of apomorphine in man.
1977 • 45 citations
Blockade of D-2 dopamine receptors strongly enhances the potency of enkephalins to inhibit dopamine-sensitive adenylate cyclase in rat neostriatum: involvement of delta- and mu-opioid receptors
1986 • 44 citations
Transdihydrolisuride, a partial dopamine receptor antagonist: Effects on monoamine metabolism
1984 • 44 citations
Differential blocking effects of several dopamine receptor antagonists for peripheral pre- and postsynaptic dopamine receptors in the anesthetized dog.
1982 • 44 citations
The enantiomers of SK&F 83566, a new selective D-1 dopamine antagonist, stereospecifically block stereotyped behaviour induced by apomorphine and by the selective D-2 agonist RU 24213
1985 • 44 citations
Evidence for the existence of vascular alpha 2-adrenergic receptors in humans.
1984 • 43 citations
Postsynaptic dopamine (DA) receptor stimulator properties of the putative DA autoreceptor-selective agonist B-HT 920 uncovered by co-treatment with the D-1 agonist SK&F 38393
1987 • 42 citations
Identification of the enantiomers of SK&F 83566 as specific and stereoselective antagonists at the striatal D-1 dopamine receptor: Comparisons with the D-2 enantioselectivity of Ro 22-1319
1984 • 42 citations
Inhibition of SKF 38393- and pergolide-induced circling in rats with unilateral 6-OHDA lesion is correlated to dopamine D-1 and D-2 receptor affinitiesin vitro
1986 • 42 citations
Neuroleptic-induced acute dyskinesias in rhesus monkeys
1981 • 41 citations
Dopamine D2 receptor mediation of the discriminative stimulus properties of LY 171555 (quinpirole)
1986 • 41 citations
Behavioral effects of chronic exposure to selective D-1 and D-2 dopamine receptor agonists
1988 • 40 citations
SCH23390 causes persistent antidopaminergic effects in vivo: Evidence for longterm occupation of receptors
1985 • 40 citations
Lisuride in the Treatment of Parkinsonism
1983 • 39 citations
Opposing roles for D-1 and D-2 dopamine receptors in regulating the excitability of growth hormone-producing cells in the snail Lymnaea stagnalis
1984 • 39 citations
Differential reversal by scopolamine and thip of the antistereotypic and cataleptic effects of neuroleptics
1981 • 39 citations
Molecular size of the canine and human brain D2 dopamine receptor as determined by radiation inactivation.
1983 • 38 citations
Differential effect of repeated treatment with l-DOPA on dopamine-D1 or -D2 receptors
1986 • 38 citations
Lergotrile mesylate: an in vivo dopamine agonist which blocks dopamine receptors in vitro.
1977 • 38 citations
Dopamine D1 receptor mediation of the discriminative stimulus properties of SKF 38393
1985 • 37 citations
The use of dopamine agonists in the treatment of schizophrenia.
1981 • 37 citations
Characterization of dopaminergic receptors in dispersed bovine parathyroid cells.
1980 • 37 citations
Effects of dopamine agonists, catecholamine depletors, and cholinergic and GABAergic drugs on acute dyskinesias in squirrel monkeys
1983 • 37 citations
Pergolide mesylate and idiopathic Parkinson disease
1982 • 36 citations
In vivo receptor binding, neurochemical and functional studies with the dopamine D-1 receptor antagonist SCH 23390
1988 • 36 citations
Nigral dopaminergic mechanisms in drug-induced circling
1983 • 36 citations
(+)- and (−)-3-PPP exhibit different intrinsic activity at striatal dopamine autoreceptors controlling dopamine synthesis
1984 • 35 citations
Parkinson's Disease. Biochemistry, Clinical Pathology, and Treatment
1983 • 35 citations
SCH 23390 may alter dopamine-mediated motor behaviour via striatal D-1 receptors
1985 • 35 citations
YM-09151-2: A potent antagonist for a peripheral D2-dopamine receptor
1982 • 35 citations
Electrophysiological studies on EMD 23 448, an indolyl-3-butylamine, in the rat: A putative selective dop amine autoreceptor agonist
1983 • 35 citations
Lisuride in Parkinson disease
1981 • 35 citations
Binding of a novel dopaminergic agonist radioligand [3H]-fenoldopam1 (SKF 82526) to D-1 receptors in rat striatum
1985 • 35 citations
[3H]SCH 23390 Binding to Human Putamen D‐1 Dopamine Receptors: Stereochemical and Structure‐Affinity Relationships Among l‐Phenyl‐1H‐3‐Benzazepine Derivatives as a Guide to D‐l Receptor Topography
1987 • 34 citations
Dopamine D1-receptor stimulation reduces neostriatal cholecystokinin release
1984 • 34 citations
The Dopamine D1 Receptor: Biochemical and Behavioral Aspects
1986 • 34 citations
Effects of selective dopamine D2-receptor agonists on the release of cholecystokinin-like immunoreactivity from rat neostriatum
1984 • 33 citations
Identification of the binding subunit of the D1-dopamine receptor by photoaffinity crosslinking.
1987 • 33 citations
Electrophysiological study of the effects of D1 and D2 dopamine antagonists on the interaction of converging inputs from the sensory-motor cortex and substantia nigra neurons in the rat
1986 • 33 citations
Potent lipophilic substituted benzamide drugs are not selective D-1 dopamine receptor antagonists in the rat
1983 • 32 citations
Evidence that Dopamine is a Neurotransmitter in the Neurointermediate Lobe of the Hypophysis
1983 • 32 citations
Differential down-regulation of D1-stimulated adenylate cyclase activity in rat forebrain after in vivo amphetamine treatments
1986 • 32 citations
[3H]SCH 23390 identifies D-1 binding sites in rat striatum and other brain areas
1986 • 32 citations
Studies in vitro with ICI 174, 864, [D-Pen2, D-Pen5]-enkephalin (DPDPE) and [D-Ala2, NMePhe4, Gly-ol]-enkephalin (DAGO)
1985 • 31 citations
Functional antagonism of D-1 and D-2 dopaminergic mechanisms affecting striatal acetylcholine release
1986 • 31 citations
The effect of apomorphine and pergolide on the potassium-evoked overflow of GABA in rat striatum studied by microdialysis
1986 • 30 citations
Selectivity of agonists and antagonists at D2dopamine receptors compared to D1 and S2receptors
1986 • 30 citations
The D1 dopamine agonist SKF 38393 functions as a discriminative stimulus in rats
1985 • 30 citations
SCH 23390 antagonizes apomorphine- and ergot-induced hypothermia
1986 • 30 citations
B-HT 920 and B-HT 958: Presynaptic effects on electrically evoked 3H-dopamine release from slices of rat nucleus accumbens
1987 • 29 citations
SCH 23390, a selective D1 dopamine receptor blocker, enhances the firing rate of nigral dopaminergic neurons but fails to activate striatal tyrosine hydroxylase
1985 • 29 citations
The use of L-DOPA in Parkinson's disease: a 20 year follow-up
1981 • 29 citations
A comparison of dopamine agonist action to inhibit locomotor activity and to induce stereotyped behaviour in the mouse
1984 • 29 citations
Evidence for a specific effect of BHT 920, an azepine derivative, on tyrosine hydroxylase in the dopaminergic system of the rat
1986 • 28 citations
D-l and D-2 dopaminergic receptors regulate protein phosphorylation in the rat neurohypophysis
1985 • 27 citations
Induction of turning by direct intrastriatal injection of dopaminomimetic drugs in mice: Pharmacological analysis of a simple screening model
1986 • 27 citations
Behavioural correlates to the dopamine D-1 and D-2 antagonists.
1984 • 27 citations
Parkinson’s Disease: Biochemistry, Clinical Pathology, and Treatment
1983 • 26 citations
D-1 dopamine receptor stimulaiton elevates plasma prolactin levels
1986 • 26 citations
Identification of Dopamine “D3′’ and “D4′’ Binding Sites, Labelled with [3H]2‐Amino‐6,7‐Dihydroxy‐ 1,2,3,4‐ Tetrahydronaphthalene, as High Agonist Affinity States of the D1 and D2 Dopamine Receptors, Respectively
1986 • 25 citations
Bromocriptine potentiates the behavioural effects of directly and indirectly acting dopamine receptor agonists in mice
1985 • 24 citations
Review on neuroleptic receptors: specificity and multiplicity of in vitro binding related to pharmacological activity
1981 • 24 citations
Hypothesis: Bromocriptine lacks intrinsic dopamine receptor stimulating properties
1985 • 24 citations
ANALYSIS OF HISTAMINE RECEPTORS IN THE CENTRAL THERMOREGULATORY MECHANISM OF Mastomys natalensis
1982 • 23 citations
“Selective” D-1 and D-2 receptor antagonists fail to differentially alter supersensitive locomotor behavior in the rat
1986 • 23 citations
Biochemical and pharmacological activities of zetidoline (DL 308-IT): a new antidopaminergic agent
1982 • 23 citations
Separation of dopamine D1 and D2 receptors
1985 • 23 citations
Characterization of Dopamine D-1 and D-2 Receptors
1986 • 23 citations
Lisuride combined with levodopa in advanced Parkinson disease
1981 • 22 citations
Inhibition of striatal tyrosine hydroxylase by low concentrations of apomorphine
1984 • 21 citations
New Directions in Tardive Dyskinesia Research
1984 • 21 citations
Central dopaminergic properties of HW-165 and its enantiomers; Trans-octahydrobenzo(f)quinoline congeners of 3-PPP
1986 • 21 citations
Bromocriptine and lisuride in Parkinson disease
1983 • 20 citations
The Bulimic Disorders
1986 • 20 citations
Activation of adenylate cyclase in rat striatum by an ergoline dopamine agonist, pergolide.
1980 • 20 citations
A homologous series of N-alkylated cis-(+)-(1 S, 2 R)-5-methoxy-1-methyl-2-aminotetralins: Central dopamine receptor antagonists showing profiles ranging from classical antagonism to selectivity for autoreceptors
1986 • 20 citations
Neuroleptic Classification: Implications for Tardive Dyskinesia
2015 • 19 citations
Behavioural effects mediated by unilateral nigral dopamine receptor stimulation in the rat
1984 • 18 citations
Regulation of agonist and antagonist binding to striatal D-1 dopamine receptors: Studies using the selective D-1 antagonist [3H]SK&F R-83566
1986 • 18 citations
Modulation by fenoldopam (SKF 82526) and bromocriptine of the electrically evoked release of vasopressin from the rat neurohypophysis
1986 • 17 citations
Behavioral Differences between Neonatal and Adult 6-Hydroxydopamine-Treated Rats to Dopamine Agonists: Relevance to Neurological Symptoms in Clinical Syndromes with Reduced Brain Dopamine
1984 • 17 citations
Stimulus Properties of Dopaminergic Drugs: Comparisons Involving Selective Agonists and Antagonists
1988 • 17 citations
Turning behaviour following nigral injections of dopamine agonists and glycine
1982 • 16 citations
Lisuride in the treatment of Parkinsonism
2009 • 16 citations
Treatment of Parkinsonʼs disease with dopamine agonists: A review
1979 • 15 citations
Effects of D-1 and D-2 Receptor Stimulation on Single Unit Activity in the Substantia Nigra and Globus Pallidus
1986 • 15 citations
Enhancing effect of dopamine blockers on evoked acetylcholine release in rat striatal slices: a classical D-2 antagonist response?
1986 • 15 citations
Clinical Pharmacology in Psychiatry: Neuroleptic and Antidepressant Research
1983 • 15 citations
Behavioural and Biochemical Studies With the Benzamide Sulpiride in Rats
1984 • 15 citations
Inhibition of K+-stimulated [3H]dopamine and [14C]acetylcholine release by the putative dopamine autoreceptor agonist, B-HT 920
1986 • 14 citations
Monkey Models of Tardive Dyskinesia1
2015 • 14 citations
Classification of neuroleptics: implications for tardive dyskinesia.
1985 • 13 citations
On the Supersensitivity of DA-Receptors After Single and Repeated Administration of Neuroleptics
1980 • 13 citations
Biochemical characteristics of D1 dopamine receptors: relationship to behavior and schizophrenia.
1986 • 13 citations
D-1/D-2 dopamine receptor interactions in the regulation of extrapyramidal motor function: studies in animal models and parkinsonian patients.
1986 • 13 citations
Dopamine Decreases the Amplitude of Excitatory Post-Synaptic Potentials in Rat Striatal Neurones
1984 • 12 citations
In Situ Molecular Size of Agonist Dopamine D-2 Binding Sites in Rat Striatum
1987 • 12 citations
Binding of [3H]SKF 38393 to Dopamine D‐l Receptors in Rat Striatum In Vitro; Estimation of Receptor Molecular Size by Radiation Inactivation
1987 • 12 citations
Evidence that diphenylhydantoin does not affect adenosine triphosphatases from brain
1976 • 12 citations
Differential electrophysiological effects of 3-PPP and its enantiomers on dopamine autoreceptors and postsynaptic receptors
1986 • 12 citations
Absence of dopamine sensitive adenylate cyclase in the A10 region, the origin of mesolimbic dopamine neurones
1979 • 11 citations
Zetidoline, a novel neuroleptic, activates nigral dopaminergic neurons in rats
1985 • 11 citations
Studies on the dopamine agonist properties of 8-amino-2-methyl-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline, a derivative of nomifensine
1978 • 11 citations
DOPAMINERGIC ERGOT DERIVATIVES: SELECTIVE AGONISTS OF A NEW CLASS OF DOPAMINE RECEPTORS?
1979 • 11 citations
A Primate Model for Tardive Dyskinesia
1980 • 10 citations
Release of cholecystokinin-like immunoreactivity from slices of dorsal and ventral striatum of rat brain
1984 • 9 citations
TREATMENT OF PARKINSONʼS DISEASE WITH A DOPAMINE PARTIAL AGONIST
1984 • 9 citations
D-1 and D-2 receptor manipulation in Cebus monkeys: implication for extrapyramidal syndromes in humans.
1986 • 8 citations
Dopamine D2 receptors photolabelled by [3H]azido-methylspiperone
1986 • 8 citations
LY141865, a D2-dopamine agonist, increases acetylcholine concentration in rat corpus striatum
1983 • 7 citations
The use of pergolide, a potent dopamine agonist, in parkinson's disease
1982 • 6 citations
New Perspectives in the Treatment of Parkinsonʼs Disease
1986 • 5 citations
Independent Dopamine D-1 and D-2 Receptor Regulation of Dopamine Agonist-induced Hyperactivity in 6-OHDA Lesioned Rats; but not in Normal Rats
1986 • 2 citations
Deleted Work
1955 • 0 citations
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