Structure of the Adrenergic and Related Receptors

Three-dimensional model of purple membrane obtained by electron microscopy

1975 • 2,259 citations

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

The distribution of positively charged residues in bacterial inner membrane proteins correlates with the trans-membrane topology

1986 • 861 citations

Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α ₂ -Adrenergic Receptor

1987 • 792 citations

cDNA eloping of bovine substance-K receptor through oocyte expression system

1987 • 748 citations

Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor.

1986 • 650 citations

A family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 636 citations

Cloning of the cDNA for the human beta 1-adrenergic receptor.

1987 • 577 citations

An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 509 citations

Isolation and nucleotide sequence of the gene encoding human rhodopsin.

1984 • 495 citations

Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene

1987 • 489 citations

Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization

1988 • 429 citations

Structural features required for ligand binding to the beta-adrenergic receptor.

1987 • 358 citations

Hypothesis about the function of membrane-buried proline residues in transport proteins.

1986 • 334 citations

Mutations that uncouple the beta-adrenergic receptor from Gs and increase agonist affinity.

1987 • 259 citations

The avian beta-adrenergic receptor: primary structure and membrane topology.

1986 • 252 citations

Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.

1987 • 248 citations

Mammalian .beta.2-adrenergic receptor: purification and characterization

1984 • 207 citations

Structure of the gene for human beta 2-adrenergic receptor: expression and promoter characterization.

1987 • 173 citations

The carboxyl terminus of the hamster β-adrenergic receptor expressed in mouse L cells is not required for receptor sequestration

1987 • 142 citations

Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes.

1987 • 137 citations

Identification and sequence of a binding site peptide of the .beta.2-adrenergic receptor

1988 • 128 citations

Multiple topogenic sequences in bovine opsin.

1987 • 115 citations

Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains.

1984 • 115 citations

Purification and characterization of the human platelet alpha 2-adrenergic receptor.

1986 • 94 citations

On the transfer of integral proteins into membranes.

1987 • 92 citations

N-glycosylation in expression and function of beta-adrenergic receptors.

1986 • 92 citations

Mammalian alpha 1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit.

1986 • 81 citations

Light-dependent conformational change at rhodopsin's cytoplasmic surface detected by increased susceptibility to proteolysis

1982 • 61 citations

Orientation of rhodopsin alpha-helices in in retinal rod outer segment membranes studied by infrared linear dichroism.

1979 • 59 citations

Functional domains of rhodopsin

1982 • 56 citations

Regulation of retinal transducin by C-terminal peptides of rhodopsin

1985 • 35 citations

Light-induced conformational changes in the extradiscal regions of bovine rhodopsin

1985 • 18 citations