Quantal release of neurotransmitter and long-term potentiation

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Quantal components of the end‐plate potential

1954 • 2,182 citations

Spontaneous subthreshold activity at motor nerve endings

1952 • 1,820 citations

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

1992 • 1,675 citations

Short-Term Synaptic Plasticity

1989 • 1,464 citations

Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase

1991 • 1,364 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system

1989 • 1,283 citations

A Requirement for the Intercellular Messenger Nitric Oxide in Long-Term Potentiation

1991 • 1,136 citations

The release of neural transmitter substances

1969 • 1,134 citations

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

1992 • 1,088 citations

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.

1991 • 1,016 citations

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

1989 • 1,015 citations

Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex

1989 • 977 citations

Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex

1990 • 893 citations

Synaptic structure and development: The neuromuscular junction

1993 • 846 citations

Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slices

1990 • 803 citations

Presynaptic mechanism for long-term potentiation in the hippocampus

1990 • 691 citations

The release of neural transmitter substances

1970 • 685 citations

NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus

1989 • 654 citations

Possible involvement of nitric oxide in long-term potentiation

1991 • 637 citations

Mechanisms Underlying Long-Term Potentiation of Synaptic Transmission

1991 • 615 citations

The measurement of synaptic delay, and the time course of acetylcholine release at the neuromuscular junction

1965 • 600 citations

Quantal analysis of synaptic potentials in neurons of the central nervous system.

1990 • 578 citations

Quantal analysis of inhibitory synaptic transmission in the dentate gyrus of rat hippocampal slices: a patch‐clamp study.

1990 • 545 citations

Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons

1991 • 486 citations

Long‐term potentiation and depression of synaptic responses in the rat hippocampus: localization and frequency dependency.

1978 • 470 citations

Associative long-term depression in the hippocampus induced by hebbian covariance

1989 • 470 citations

Origin of variability in quantal size in cultured hippocampal neurons and hippocampal slices.

1990 • 467 citations

Glutamate-induced long-term potentiation of the frequency of miniature synaptic currents in cultured hippocampal neurons

1992 • 421 citations

NMDA application potentiates synaptic transmission in the hippocampus

1988 • 421 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ

1992 • 373 citations

Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents

1992 • 372 citations

The kinetics of transmitter release at the frog neuromuscular junction

1972 • 359 citations

Long-term potentiation and long-term depression in the neocortex

1992 • 329 citations

Postsynaptic factors control the duration of synaptic enhancement in area CA1 of the hippocampus

1991 • 319 citations

Stable depression of potentiated synaptic responses in the hippocampus with 1–5 Hz stimulation

1990 • 303 citations

Correlation between long‐term potentiation and release of endogenous amino acids from dentate gyrus of anaesthetized rats.

1986 • 289 citations

Long-term potentiation is associated with increases in quantal content and quantal amplitude

1992 • 288 citations

Quantal analysis and synaptic efficacy in the CNS

1991 • 287 citations

Putative Single Quantum and Single Fibre Excitatory Postsynaptic Currents Show Similar Amplitude Range and Variability in Rat Hippocampal Slices

1992 • 257 citations

Transmission between pairs of hippocampal slice neurons: quantal levels, oscillations, and LTP

1991 • 241 citations

Ca2+ Entry via postsynaptic voltage-sensitive Ca2+ channels can transiently potentiate excitatory synaptic transmission in the hippocampus

1992 • 237 citations

Multimodal Distribution of Frog Miniature Endplate Potentials in Adult, Denervated, and Tadpole Leg Muscle

1974 • 210 citations

Quantal analysis of excitatory synaptic action and depression in hippocampal slices

1991 • 197 citations

Voltage dependence of agonist effectiveness at the frog neuromuscular junction: resolution of a paradox.

1975 • 190 citations

Learning-related synaptic plasticity: LTP and LTD

1991 • 165 citations

Isolated NMDA receptor-mediated synaptic responses express both LTP and LTD

1992 • 133 citations

The Neuromuscular Junction

1988 • 116 citations

Quantal independence and uniformity of presynaptic release kinetics at the frog neuromuscular junction

1972 • 113 citations

The role of N-methyl-d-aspartate receptors in the generation of short-term potentiation in the rat hippocampus

1989 • 74 citations

Heterosynaptic long-term depression is facilitated by blockade of inhibition in area CA1 of the hippocampus

1991 • 69 citations

Long-term depression at synapses in slices of rat hippocampus can be induced by bursts of postsynaptic activity

1990 • 63 citations

Non-uniform release at the frog neuromuscular junction: evidence of morphological and physiological plasticity

1987 • 57 citations

Is the quantum of transmitter release composed of subunits? A critical analysis in the mouse and frog

1981 • 55 citations

Non-uniform responses to Ca2+ along the frog neuromuscular junction: Effects on the probability of spontaneous and evoked transmitter release

1991 • 48 citations

Neuromuscular junction

1988 • 28 citations

Long-term potentiation of synaptic responses in the rat dentate gyrus is due to increased quantal content

1991 • 14 citations