Neurotransmitter regulation of dopamine neurons in the ventral tegmental area

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1980 • 334 citations

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Selective dopamine antagonists reduce nicotine self-administration

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Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area

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Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release

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1987 • 152 citations

Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.

1987 • 151 citations

Local cooling of pre‐frontal cortex induces pacemaker‐like firing of dopamine neurons in rat ventral tegmental area in vivo

1989 • 151 citations

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Two-color immunohistochemistry for dopamine and GABA neurons in rat substantia nigra and zona incerta

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1985 • 148 citations

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1991 • 145 citations

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1991 • 145 citations

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1987 • 145 citations

Autoradiographic localization of μ-opioid and neurotensin receptors within the mesolimbic dopamine system

1989 • 143 citations

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1988 • 141 citations

Biochemical investigation on the localization of the cholecystokinin octapeptide in dopaminergic neurons originating from the ventral tegmental area of the rat

1981 • 140 citations

Anatomical analysis of the involvement of mesolimbocortical dopamine in the locomotor stimulant actions ofd-amphetamine and apomorphine

1988 • 140 citations

Ventral mesencephalic neurons containing both cholecystokinin‐ and tyrosine hydroxylase‐like immunoreactivities project to forebrain regions

1989 • 139 citations

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Dopaminergic mechanisms in the pathogenesis of schizophrenia ¹

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The behavioural effects of enkephalin analogues injected into the ventral tegmental area and globus pallidus

1981 • 137 citations

Characterization of dopamine release in the substantia nigra by in vivo microdialysis in freely moving rats

1991 • 137 citations

Role of endogenous substance P in stress-induced activation of mesocortical dopamine neurones

1983 • 134 citations

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1988 • 133 citations

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1988 • 133 citations

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1981 • 131 citations

Neurotensin depolarizes substantia nigra dopamine neurones

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Neuroanatomical boundaries of the reward-relevant opiate-receptor field in the ventral tegmental area as mapped by the conditioned place preference method in rats

1987 • 130 citations

Increased spontaneous activity following substance P infusion into A10 dopaminergic area

1978 • 129 citations

Neurotensin in vitro markedly reduces the affinity in subcortical limbic ³H‐N‐propylnorapomorphine binding sites*

1983 • 128 citations

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1992 • 128 citations

Responses of monkey midbrain dopamine neurons during delayed alternation performance

1991 • 126 citations

5.HT1 receptors in the vertebrate brain

1989 • 126 citations

Cholecystokinin and tyrosine hydroxylase messenger RNAs in neurons of rat mesencephalon: peptide/monoamine coexistence studies using in situ hybridization combined with immunocytochemistry

1989 • 126 citations

GABA-labeled terminals form proportionally more synapses with dopaminergic neurons containing low densities of tyrosine hydroxylase-immunoreactivity in rat ventral tegmental area

1991 • 126 citations

CHOLINE ACETYLTRANSFERASE CONTENT IN DISCRETE REGIONS OF THE RAT BRAIN STEM

1975 • 126 citations

Topography of substantia nigra innervation by D1 receptor-containing striatal neurons

1987 • 124 citations

Facilitation of sexual behaviors in the male rat associated with Intra-VTA injections of opiates

1990 • 124 citations

Cholinergic involvement in lateral hypothalamic rewarding brain stimulation

1985 • 124 citations

Burst firing of mesencephalic dopamine neurons is inhibited by somatodendritic application of kynurenate

1991 • 122 citations

Autoradiographic localization of [3H]nicotine binding sites in the rat brain

1985 • 121 citations

A topographic localization of enkephalin on the dopamine neurons of the rat substantia nigra and ventral tegmental area demonstrated by combined histofluorescence-immunocytochemistry

1980 • 121 citations

Electrophysiological effects of neurotensin on dopaminergic neurones of the ventral tegmental area of the rat in vitro

1989 • 118 citations

The distribution of cholecystokinin octapeptide-like structures in the lower brain stem of the rat: An immunohistochemical analysis

1983 • 117 citations

Behavioral analysis of the effect of substance P injected into the ventral mesencephalon on investigatory and spontaneous motor behavior in the rat

1985 • 116 citations

Enkephalin release into the ventral tegmental area in response to stress: modulation of mesocorticolimbic dopamine

1987 • 116 citations

Opposite changes in dopamine utilization in the nucleus accumbens and the frontal cortex after electrolytic lesion of the median raphe in the rat

1981 • 115 citations

A comparison of the effects of intra-accumbens injections of amphetamine and morphine on reinstatement of heroin intravenous self-administration behavior

1988 • 114 citations

β-Endorphin-induced locomotor stimulation and reinforcement are associated with an increase in dopamine release in the nucleus accumbens

1991 • 114 citations

Striato-nigral dynorphin and substance P pathways in the rat

1986 • 113 citations

Effects of apamin on the discharge properties of putative dopamine-containing neurons in vitro

1988 • 113 citations

Mapping of brain areas expressing RNA homologous to two different acetylcholine receptor alpha-subunit cDNAs.

1986 • 112 citations

Correspondence between high affinity ¹²⁵I‐neurotensin binding sites and dopaminergic neurons in the rat substantia nigra and ventral tegmental area: A combined radioautographic and immunohistochemical light microscopic study

1989 • 112 citations

Neurotensin neurons in the ventral tegmental area project to the medial nucleus accumbens

1984 • 111 citations

Self‐Stimulation and Drug Reward Mechanisms

1992 • 111 citations

CHOLINE ACETYLTRANSFERASE CONTENT IN DISCRETE REGIONS OF THE RAT BRAIN STEM

1975 • 109 citations

Dendro-dendritic synapses in substantia nigra: Descriptions based on analysis of serial sections

1983 • 108 citations

Autoradiographic localization of ?-aminobutyric acidA receptors within the ventral tegmental area

1992 • 106 citations

Dopaminergic neurons in the rat ventral tegmental area. II. Evidence for autoregulation

1981 • 105 citations

Visualization of neurokinin-3 receptor sites in rat brain using the highly selective ligand [3H]senktide

1990 • 105 citations

Visualization of a novel serotonin recognition site (5-HT1D) in the human brain by autoradiography

1988 • 105 citations

Neurotensin modulates dopamine neurotransmission at several levels along brain dopaminergic pathways

1989 • 104 citations

The influence of striatal stimulation and putative neurotransmitters on identified neurones in the rat substantia nigra

1981 • 104 citations

Serotonin Receptor Subtypes

1991 • 103 citations

Pertussis toxin blocks autoreceptor-mediated inhibition of dopaminergic neurons in rat substantia nigra

1987 • 101 citations

Nicotine and morphine differentially activate brain dopamine in prefrontocortical and subcortical terminal fields: effects of acute and repeated injections.

1992 • 101 citations

The localization of receptor binding sites in the substantia nigra and striatum of the rat

1979 • 101 citations

Quantitative autoradiographic analysis of the distribution of binding sites for [125I]Bolton Hunter derivatives of eledoisin and substance P in the rat brain

1986 • 100 citations

Dual ultrastructural localization of enkephalin and tyrosine hydroxylase immunoreactivity in the rat ventral tegmental area: multiple substrates for opiate-dopamine interactions

1992 • 100 citations

Influence of cholecystokinin on central monoaminergic pathways

1983 • 99 citations

Electron microscopic localization of neurotensin binding sites in the midbrain tegmentum of the rat. I. Ventral tegmental area and the interfascicular nucleus

1989 • 98 citations

A quantitative correlation between single unit activity and fluorescence intensity of dopamine neurones in zona compacta of substantia nigra, as demonstrated under the influence of nicotine and physostigmine

1976 • 97 citations

Behavioral activation induced in the rat by substance P infusion into ventral tegmental area: Implication of dopaminergic A10 neurones

1979 • 97 citations

The cholinergic innervation of the rat substantia nigra: a light and electron microscopic immunohistochemical study

1988 • 97 citations

Evidence for an involvement of D1 and D2 dopamine receptors in mediating nicotine-induced hyperactivity in rats

1991 • 96 citations

Dopaminergic neurons: Effect of acute and chronic morphine administration on single cell activity and transmitter metabolism

1978 • 95 citations

Substance P and neurokinin A regulate by different mechanisms dopamine release from dendrites and nerve terminals of the nigrostriatal dopaminergic neurons

1988 • 94 citations

3H-SCH 23390 binding sites in the rat substantia nigra: Evidence for a presynaptic localization and innervation by dopamine

1986 • 93 citations

A comparative autoradiographic study of the distributions of substance P and eledoisin binding sites in rat brain

1986 • 93 citations

Cholecystokinin-dopamine coexistence: electrophysiological actions corresponding to cholecystokinin receptor subtype

1986 • 93 citations

Ventral tegmental site of opiate reward: Antagonism by a hydrophilic opiate receptor blocker

1983 • 91 citations

Opposing Roles of Dopamine D₁ and D₂ Receptors in Nigral γ‐[³H]Aminobutyric Acid Release?

1987 • 91 citations

Association of dopamine d, and d2 receptors with specific cellular elements in the basal ganglia of the cat: The uneven topography of dopamine receptors in the striatum is determined by intrinsic striatal cells, not nigrostriatal axons

1988 • 91 citations

Substance P, neurotensin and enkephalin injections into the ventral tegmental area: comparative study on dopamine turnover in several forebrain structures

1989 • 90 citations

Opposite effects of μ and κ opiates on the firing-rate of dopamine cells in the substantia nigra of the rat

1987 • 90 citations

Conditioning of Opioid Reinforcement: Neuroanatomical and Neurochemical Substrates

1992 • 89 citations

The significance of dendritic release of transmitter and protein in the substantia nigra

1985 • 88 citations

Neuropharmacological studies on the nigro-striatal and raphe-striatal system in the rat

1978 • 88 citations

Tyrosine hydroxylase and methionine-enkephalin in the human mesencephalon

1983 • 88 citations

Increased utilization of dopamine in the nucleus accumbens but not in the cerebral cortex after dorsal raphe lesion in the rat

1979 • 86 citations

Locomotor activity initiated by microinfusions of picrotoxin into the ventral tegmental area

1979 • 86 citations

Cholecystokinin-like peptides potentiate apomorphine-induced inhibition of dopamine neurons

1983 • 86 citations

The effects of intranigral GABA and dynorphin A injections on striatal dopamine and GABA release: Evidence that dopamine provides inhibitory regulation of striatal GABA neurons via D2 receptors

1990 • 85 citations

Striatonigral GABA, dynorphin, substance P and neurokinin A modulation of nigrostriatal dopamine release: evidence for direct regulatory mechanisms

1990 • 85 citations

Neurotensin self-injection in the ventral tegmental area

1987 • 84 citations

Opioid receptor subtypes associated with ventral tegmental facilitation of lateral hypothalamic brain stimulation reward

1987 • 84 citations

A possible pacemaker mechanism in pars compacta neurons of the guinea-pig substantia nigra revealed by various ion channel blocking agents

1989 • 84 citations

Synthesis and Release of Dopamine in Rat Brain: Comparison Between Substantia Nigra Pars Compacta, Pars Reticulata, and Striatum

1989 • 84 citations

Substance K excites dopaminergic and non-dopaminergic neurons in rat substantia nigra

1985 • 84 citations

Sensitization to repeated enkephalin administration into the ventral tegmental area of the rat. II. Involvement of the mesolimbic dopamine system.

1985 • 83 citations

Symmetric bilateral changes in dopamine release from the caudate nuclei of the cat induced by unilateral nigral application of glycine and gaba-related compounds

1979 • 83 citations

Dynorphin-containing pathways in the substantia nigra and ventral tegmentum: A double labeling study using combined immunofluorescence and retrograde tracing

1985 • 82 citations

Neuromedin N: High affinity interaction with brain neurotensin receptors and rapid inactivation by brain synaptic peptidases

1986 • 81 citations

Multiple tachykinin receptors in guinea pig brain. High densities of substance K (neurokinin a) binding sites in the substantia nigra

1985 • 81 citations

Receptor Subtypes in Opioid and Stimulant Reward

1992 • 80 citations

GABA axons in synaptic contact with dopamine neurons in the substantia nigra: double immunocytochemistry with biotin-peroxidase and protein A-colloidal gold

1985 • 79 citations

Effects of dopaminergic nucleus accumbens lesions on the acquisition of schedule induced self injection of nicotine in the rat

1982 • 78 citations

Analysis of expression of cholecystokinin in dopamine cells in the ventral mesencephalon of several species and in humans with schizophrenia.

1990 • 78 citations

[3H]N-methyl-carbamylcholine, a new radioligand specific for nicotinic acetylcholine receptors in brain

1987 • 77 citations

Regulation by second messengers of the slowly activating, voltage‐dependent potassium current expressed in Xenopus oocytes.

1992 • 77 citations

Investigation of behavioral and electrophysiological responses induced by selective stimulation of CCKB receptors by using a new highly potent CCK analog, BC 264

1990 • 77 citations

Substance K and substance P differentially modulate mesolimbic and mesocortical systems

1985 • 77 citations

The actions of opiates in the rat substantia nigra: An electrophysiological analysis

1983 • 76 citations

Regionally specific effects of acute and chronic nicotine on rates of catecholamine and 5-hydroxytryptamine synthesis in rat brain

1989 • 76 citations

Selective activation of mesolimbic and mesocortical dopamine metabolism in rat brain by infusion of a stable substance P analogue into the ventral tegmental area

1986 • 76 citations

Evidence for the presynaptic localization of opiate binding sites on striatal efferent fibers

1984 • 76 citations

Different neuronal location of [3H]SCH 23390 binding sites in pars reticulata and pars compacta of the substantia nigra in the rat

1986 • 75 citations

Autoradiographic visualization of NK-3 tachykinin binding sites in the rat brain, utilizing [3H]senktide

1990 • 75 citations

Relationships between Mesolimbic Dopamine Function and Eating Behaviora

1988 • 75 citations

Neurotensin and cholecystokinin microinjected into the ventral tegmental area modulate microdialysate concentrations of dopamine and metabolites in the posterior nucleus accumbens

1990 • 74 citations

Forebrain projections from cholecystokininlike‐immunoreactive neurons in the rat midbrain

1989 • 73 citations

Glutamate-Like Immunoreactivity is Present within Cholinergic Neurons of the Laterodorsal Tegmental and Pedunculopontine Nuclei

1991 • 73 citations

Inhibition of non-dopamine cells in the ventral tegmental area by benzodiazepines: relationship to A10 dopamine cell activity

1987 • 72 citations

Regulation of spontaneous activity and oscillatory spike firing in rat midbrain dopamine neurons recorded in vitro

1991 • 72 citations

Modulation of Dendritic Release of Dopamine by N‐Methyl‐D‐Aspartate Receptors in Rat Substantia Nigra

1989 • 72 citations

Chapter 18 Influence of the ascending monoaminergic systems on the activity of the rat prefrontal cortex

1991 • 71 citations

Effect of picrotoxin and nipecotic acid on inhibitory response of dopaminergic neurons in the ventral tegmental area to stimulation of the nucleus accumbens

1980 • 71 citations

Dopamine receptors in the ventral tegmental area affect motor, but not motivational or reflexive, components of copulation in male rats

1991 • 70 citations

Neurotensin modulates autoreceptor mediated dopamine effects on midbrain dopamine cell activity

1991 • 70 citations

Pre-exposure to amphetamine but not nicotine sensitizes rats to the motor activating effect of cocaine

1991 • 70 citations

Effect of the immunoneutralization of substance P in the cat substantia nigra on the release of dopamine from dendrites and terminals of dopamine-ergic neurons

1978 • 69 citations

Presynaptic modulation of the release of GABA by GABAA receptors in pars compacta and by GABAB receptors in pars reticulata of the rat substantia nigra

1988 • 69 citations

Effect of 6-hydroxydopamine lesions of the medial forebrain bundle on the distribution of cholecystokinin in rat forebrain

1982 • 68 citations

Tolbutamide reverses membrane hyperpolarisation induced by activation of D2 receptors and GABAB receptors in isolated substantia nigra neurones

1990 • 68 citations

Evidence for an involvement of 5-hydroxytryptaminergic neurones in the maintenance of operant behaviour by positive reinforcement

1991 • 68 citations

Self-administration of small amounts of morphine through glass micropipettes into the ventral tegmental area of the rat

1989 • 67 citations

Nicotine-induced sensitization to ambulatory stimulant effect produced by daily administration into the ventral tegmental area and the nucleus accumbens in rats

1992 • 67 citations

5-Hydroxytryptamine and 5-hydroxytryptaminergic-dopaminergic interactions in the ventral tegmental area of rat brain

1982 • 65 citations

Sensitization to repeated enkephalin administration into the ventral tegmental area of the rat. I. Behavioral characterization.

1985 • 65 citations

Intravenous GABA agonist administration stimulates firing of A10 dopaminergic neurons

1980 • 64 citations

Response of dopamine neurons in substantia nigra to muscimol

1978 • 64 citations

Autogenous oscillatory potentials in neurons of the guinea pig substantia nigra pars compacta in vitro

1989 • 64 citations

Dorsal raph� stimulation modifies striatal-evoked antidromic invasion of nigral dopaminergic neurons in vivo

1991 • 64 citations

The influence of electrical stimulation of certain brain regions on the concentration of acetylcholinesterase in rabbit cerebrospinal fluid

1979 • 64 citations

Locomotion induced by ventral tegmental microinjections of a nicotinic agonist

1990 • 64 citations

Repeated neurotensin administration in the ventral tegmental area: Effects on baseline and d-amphetamine-induced locomotor activity

1986 • 64 citations

Cholecystokinin potentiates dopamine inhibition of mesencephalic dopamine neurons in vitro

1987 • 64 citations

Roles of intracellular cAMP and protein kinase A in the actions of dopamine and neurotensin on midbrain dopamine neurons

1992 • 63 citations

Immunocytochemical evidence for direct connections between neurotensin-containing axons and dopaminergic neurons in the rat ventral midbrain tegmentum

1989 • 63 citations

Effect of intranigral injections of dynorphin, dynorphin fragments and α-neoendorphin on rotational behaviour in the rat

1984 • 63 citations

Feeding elicited by dynorphin (1–13) microinjections into the ventral tegmental area in rats

1988 • 63 citations

GTP‐mediated macromolecular interactions: the common features of different systems

1988 • 63 citations

Neurotensin counteracts apomorphine-induced inhibition of dopamine release as studied by microdialysis in rat neostriatum

1989 • 63 citations

Morphine place conditioning is differentially affected by CCKA and CCKB receptor antagonists

1992 • 62 citations

The colocalization of cholecystokinin and tyrosine hydroxylase mRNAs in mesencephalic dopaminergic neurons in the rat brain examined byin situ hybridization

1989 • 62 citations

Cellular Mechanisms of Behavioral Sensitization to Drugs of Abusea

1992 • 62 citations

Opioid δ agonists and endogenous enkephalins induce different emotional reactivity than μ agonists after injection in the rat ventral tegmental area

1991 • 62 citations

Neurochemical Studies of the Mesolimbic Dopaminergic Pathway: Somatodendritic Mechanisms and GABAergic Neurones in the Rat Ventral Tegmentum

1980 • 61 citations

Behavioral analysis of the effect of neurotensin injected into the ventral mesencephalon on investigatory and spontaneous motor behavior in the rat

1985 • 60 citations

Action of nicotine on accumbens dopamine and attenuation with repeated administration

1989 • 60 citations

An assessment of the spontaneous activity of rats administered morphine, phencyclidine, or nicotine using automated and observational methods

1984 • 60 citations

The selective NK₃ receptor agonist senktide excites a subpopulation of dopamine‐sensitive neurones in the rat substantia nigra pars compacta in vitro

1992 • 59 citations

Further indication that distinct dopaminergic subsets project to the rat cerebral cortex: lack of colocalization with neurotensin in the superficial dopaminergic fields of the anterior cingulate, motor, retrosplenial and visual cortices

1991 • 59 citations

A non-cholinergic function for acetylcholinesterase in the substantia nigra: Behavioural evidence

1984 • 59 citations

Potentiation of central reward by localised perfusion of acetylcholine and 5-hydroxytryptamine

1976 • 59 citations

Behavioural and biochemical responses following activation of midbrain dopamine pathways by receptor selective neurokinin agonists

1991 • 58 citations

Properties of Quisqualate‐Sensitive L‐[³H]Glutamate Binding Sites in Rat Brain as Determined by Quantitative Autoradiography

1988 • 58 citations

Cholinergic mediation in the ventral tegmental area of α-melanotropin induced excessive grooming: Changes of the dopamine activity in the nucleus accumbens and caudate putamen

1988 • 58 citations

Behavioural effects of selective tachykinin agonists in midbrain dopamine regions

1991 • 58 citations

Striatonigral and pallidonigral pathways studied by a combination of retrograde horseradish peroxidase tracing and a pharmacohistochemical method for γ-aminobutyric acid transaminase

1985 • 57 citations

Localization of GABAA-receptor γ2-subunit mRNA-containing neurons in the rat central nervous system

1992 • 57 citations

Neurokinin agonists differentially affect A9 and A10 dopamine cells in the rat

1992 • 57 citations

Autoradiographic localization of delta opioid receptors within the mesocorticolimbic dopamine system using radioiodinated [2‐d‐penicillamine, 5‐d‐penicillamine]enkephalin (¹²⁵I‐DPDPE)

1990 • 56 citations

Molecular Characterization of the Three Tachykinin Receptors

1991 • 55 citations

Distribution, projection and dopaminergic regulation of the neurokinin B mRNA-containing neurons of the rat caudate-putamen

1989 • 55 citations

Substance K and substance P in the ventral tegmental area

1985 • 55 citations

Neurotensin Decreases the Affinity of Dopamine D² Agonist Binding by a G Protein‐Independent Mechanism

1991 • 54 citations

Effects of ICI 169,369, a selective serotonin2 antagonist, in electrophysiological tests predictive of antipsychotic activity.

1989 • 54 citations

Co-localization of tyrosine hydroxylase and glutamate decar☐ylase in a subpopulation of single nigrotectal projection neurons

1991 • 54 citations

Neurotensin and its analogs—Correlation of specific binding with stimulation of cyclic GMP formation in neuroblastoma clone N1E-115

1986 • 54 citations

Studies on neurotensin catecholamine interactions in the hypothalamus and in the forebrain of the male rat

1984 • 54 citations

Activation of mesencephalic dopamine neurons by chemical stimulation of the nucleus tegmenti pedunculopontinus pars compacta

1988 • 54 citations

Endogenous enkephalin modulation of dopamine neurons in ventral tegmental area

1986 • 53 citations

Cholecystokinin (CCK) and schizophrenia: the selective CCKB antagonist LY262691 decreases midbrain dopamine unit activity

1991 • 53 citations

Neurotensin-induced dopamine release in vivo and in vitro from substantia nigra and nucleus caudate.

1990 • 52 citations

Differential sensitivity of presumed dopaminergic and non-dopaminergic neurones in rat substantia nigra to electrophoretically applied substance P

1982 • 52 citations

Increases in dopamine utilization in certain limbic dopamine terminal populations after a short period of intermittent exposure of male rats to cigarette smoke

1986 • 51 citations

Dopamine and opiate receptors: Localization in the striatum and evidence for their axoplasmic transport in the nigrostriatal and striatonigral pathways

1986 • 51 citations

Population response of midbrain dopaminergic neurons to neuroleptics: further studies on time course and nondopaminergic neuronal influences

1987 • 51 citations

Bilateral projection of nigro-collicular neurons: An electrophysiological analysis in the rat

1977 • 51 citations

Specific role of n-acetyl-aspartyl-glutamate in the in vivo regulation of dopamine release from dendrites and nerve terminals of nigrostriatal dopaminergic neurons in the cat

1991 • 51 citations

Effects of drugs on the formation of 3-methoxytyramine, a dopamine metabolite, in the substantia nigra, striatum, nucleus accumbens and tuberculum olfactorium of the rat

1979 • 51 citations

Substantia nigra as a site of origin of dopamine-dependent motor syndromes induced by stimulation of μ and δ opioid receptors

1989 • 50 citations

Dopamine and conditioned reinforcement

1991 • 50 citations

Reserpine-insensitive dopamine release in the substantia nigra?

1991 • 50 citations

Facilitation of brain stimulation reward by mesencephalic injections of neurotensin-(1–13)

1992 • 49 citations

Differential effects of selective lesions of cholinergic and dopamingergic neurons on serotonin‐type 1 receptors in rat brain

1987 • 49 citations

The involvement of 5-hydroxytryptamine in the release of dendritic dopamine from slices of rat substantia nigra

1983 • 49 citations

Determination of acetylcholine in discrete regions of the rat brain

1977 • 48 citations

Opioid receptor subtypes associated with ventral tegmental facilitation and periaqueductal gray inhibition of feeding

1987 • 48 citations

Ultrastructural localization of neurotensin‐like immunoreactivity within dense core vesicles in perikarya, but not terminals, colocalizing tyrosine hydroxylase in the rat ventral tegmental area

1991 • 48 citations

Does cholecystokinin colocalize with dopamine in the human substantia nigra?

1989 • 48 citations

Neurotensin innervation of the human cerebral cortex: lack of colocalization with catecholamines

1990 • 48 citations

Actions of substance P and opiates in the rat substantia nigra

1982 • 47 citations

Evidence that the unilateral activation of 5‐HT_1D receptors in the substantia nigra of the guinea‐pig elicits contralateral rotation

1991 • 47 citations

Electrophysiological studies on the specificity of the cholecystokinin antagonist proglumide

1987 • 47 citations

GABA terminal autoreceptors in the pars compacta and in the pars reticulata of the rat substantia nigra are GABAB

1990 • 46 citations

In vivo release of substance P in the cat substantia nigra

1979 • 46 citations

Neurotensin in the ventromedial mesencephalon of the rat: Anatomical and functional considerations

1984 • 46 citations

Evidence for dopamine release and metabolism beyond the control of nerve impulses and dopamine receptors in rat substantia nigra

1985 • 46 citations

Inhibitory effects of GABA, L-glutamic acid and nicotine on the potassium-evoked release of subsaance P in substantia nigra slices of the rat

1981 • 45 citations

Glutamate uptake, glutamate decarboxylase and choline acetyltransferase in subcortical areas after sensorimotor cortical ablations in the cat

1983 • 45 citations

Substance P afferents have synaptic contacts with dopaminergic neurons in the ventral tegmental area of the rat

1990 • 45 citations

Neurotensin Binding to Dopamine

1990 • 45 citations

5-HT2 receptor antagonists reverse amphetamine-induced slowing of dopaminergic neurons by interfering with stimulated dopamine synthesis.

1992 • 45 citations

Serotonin-like immunoreactive cells and fibres in the rat ventromedial mesencephalic tegmentum

1989 • 44 citations

Asymmetrical distribution of neurotensin immunoreactivity following unilateral injection of 6-hydroxydopamine in rat ventral tegmental area (VTA)

1989 • 44 citations

Electrophysiological changes in substantia nigra after dynorphin administration

1986 • 43 citations

Injection of tachykinins and selective neurokinin receptor ligands into the substantia nigra reticulata increases striatal dopamine and 5-hydroxytryptamine metabolism

1991 • 43 citations

Cholecystokinin and neurotensin mRNAs are differentially expressed in subnuclei of the ventral tegmental area

1990 • 43 citations

Acute motor effects of N-methyl-d-aspartic acid and kainic acid applied focally to mesencephalic dopamine cell body regions in the rat

1980 • 43 citations

Mesencephalic Dopaminergic Neurons: Role in the General Economy of the Brain

1988 • 43 citations

Effect of inhibiting enkephalin catabolism in the VTA on motor activity and extracellular dopamine

1992 • 42 citations

Neurotensin, substance P, neurokinin-α, and enkephalin: injection into ventral tegmental area in the rat produces differential effects on operant responding

1989 • 42 citations

Effects of drugs on hyperactivity and aggression induced by raphe lesions in rats

1978 • 42 citations

Comparison of the substance P- and dynorphin-containing projections to the substantia nigra: a radioimmunocytochemical and biochemical study

1985 • 41 citations

Regulation of neurotensin-containing neurons in the rat striatum and substantia nigra. Effects of unilateral nigral lesion with 6-hydroxydopamine on neurotensin content and its binding site density

1990 • 41 citations

Bilateral tectal projection of single nigrostriatal dopamine cells in the rat

1989 • 40 citations

Microinjection of cholecystokinin into the rat ventral tegmental area potentiates dopamine‐induced hypolocomotion

1989 • 40 citations

Neurophysiological investigation of effects of the D‐1 agonist SKF 38393 on tonic activity of substantia nigra dopamine neurons

1987 • 40 citations

Electron microscopic localization of cholinergic terminals in the rat substantia nigra: An immunocytochemical study

1989 • 40 citations

Increased release of preloaded [3H]GABA from substantia nigra in vivo following stimulation of caudate nucleus and globus pallidus

1978 • 40 citations

Ultrastructural single‐ and double‐label immunohistochemical studies of substance P‐containing terminals and dopaminergic neurons in the substantia nigra in pigeons

1991 • 39 citations

Differential effects of D1 and D2 dopamine receptor agonists on substantia nigra pars reticulata neurons

1990 • 39 citations

Autoradiographic Studies of Serotonin Receptors

1988 • 39 citations

Acute amphetamine-induced subsensitivity of A10 dopamine autoreceptors in vitro

1991 • 37 citations

GABA-induced locomotor activity in the rat, after bilateral injection into the ventral tegmental area

1979 • 37 citations

Quantitation of N-acetyl-aspartyl-glutamate in microdissected rat brain nuclei and peripheral tissues: findings with a novel liquid phase radioimmunoassay

1988 • 36 citations

An electrophysiological action of acetylcholinesterase independent of its catalytic site

1988 • 36 citations

Task-specific effects of nicotine in ratsIntracranial self-stimulation and locomotor activity

1986 • 36 citations

Excitation of substantia nigra pars compacta neurones by 5-hydroxy-tryptamine in-vitro

1991 • 35 citations

Chapter 17 Regulation by nicotine of midbrain dopamine neurons

1989 • 35 citations

Intranigral substance P modulation of striatal dopamine: interaction with N-terminal and C-terminal substance P fragments

1990 • 35 citations

Marked variations of the relative distributions of neurotensin and neuromedin N in micropunched rat brain areas suggest differential processing of their common precursor

1991 • 34 citations

Opioid Control of the In Vitro Release of Cholecystokinin‐Like Material from the Rat Substantia Nigra

1992 • 34 citations

On the origin of dynorphin A and α-neo-endorphin in the substantia nigra

1984 • 34 citations

GABAergic mechanisms within the ventral tegmental area: Involvement of dopaminergic (A 10) and non-dopaminergic neurones

1982 • 33 citations

kappa-Opioid inhibition of [3H]dopamine release from rat ventral mesencephalic dissociated cell cultures.

1992 • 33 citations

Comparative studies of locomotor behavior following microinjections of muscimol into various sites in the paramedian tegmentum

1989 • 33 citations

Evidence that nigral substance P controls the activity of the nigrotectal GABAergic pathway

1984 • 33 citations

Chronic systemic administration of amphetamine increases food intake to morphine, but not to U50-488H, microinjected into the ventral tegmental area in rats

1990 • 33 citations

Neuronal responses to iontophoretically applied dopamine, glutamate, and GABA of identified dopaminergic cells in the rat substantia nigra after kainic acid-induced destruction of the striatum

1982 • 32 citations

Comparison of the effects of dopamine D 1 and D 2 receptor antagonists on rat striatal, limbic and nigral dopamine synthesis and utilisation

1987 • 32 citations

Behavioral and biochemical assessment of time-related changes in globus pallidus and striatal dopamine induced by intranigrally administered neurotensin

1985 • 32 citations

Neurotensin reduces the affinity of dopamine D2 receptors in membranes from post mortem human caudate-putamen

1990 • 31 citations

Behavioral cross-sensitization between cocaine and enkephalin in the A10 dopamine region

1988 • 31 citations

Preferential release of neuroactive amino acids from the ventrolateral medulla of the rat in vivo as measured by microdialysis

1990 • 30 citations

Pharmacologically defined M1 and M2 muscarinic cholinergic binding sites in the cat's substantia nigra: development and maturity

1991 • 30 citations

Cholecystokinin and Gastrin Forms in the Nervous System

1985 • 30 citations

Opioid peptide biosynthesis: enzymatic selectivity and regulatory mechanisms

1987 • 30 citations

[3H]quinuclidinyl benzylate and [3H]GABA receptor binding in rat substantia nigra after 6-hydroxy-dopamine lesions

1980 • 30 citations

New wave of non-NMDA excitatory amino acid receptors

1991 • 29 citations

Glycine Receptors in the Human Substantia Nigra as Defined by [³H]Strychnine Binding

1982 • 29 citations

Cholinergic stimulation of substantia nigra: effects on feeding, drinking and sexual behaviour in the male rat

1991 • 29 citations

Behavioral and pharmacological specificity of the feeding elicited by cholinergic stimulation of the substantia nigra in the rat.

1983 • 28 citations

Evidence for a functional role of dopamine type-1 (D-1) receptors in the substantia nigra of rats

1986 • 28 citations

Effect of typical and atypical neuroleptics on the behavioural consequences of activation by muscimol of mesolimbic and nigro-striatal dopaminergic pathways in the rat

1991 • 28 citations

Identification of Intact Neurotensin in the Substantia Nigra After Its Retrograde Axonal Transport in Dopaminergic Neurons

1991 • 27 citations

Correlation between immunochemical characteristics and immunohistochemical applicability of nine lines of monoclonal antibodies against rat brain glutaminase.

1988 • 27 citations

Phosphorylation by Cyclic AMP‐Dependent Protein Kinase Modulates Agonist Binding to the D₂ Dopamine Receptor

1991 • 27 citations

Rapid desensitization of dopamine release induced by neurotensin and neurotensin fragments.

1990 • 27 citations

Inhibitory effects of the κ opiate U50,488 in the substantia nigra pars reticulata

1990 • 27 citations

Neuroleptic suppression of feeding and oral stereotypy following microinjections of carbachol into substantia nigra

1980 • 27 citations

Microtopography of d1 dopaminergic binding sites in the human substantia nigra: An autoradiographic study

1990 • 26 citations

Contralateral circling behavior induced by intranigral microinjections of taurine and GABA in rats

1985 • 26 citations

Effects of neurotensin on midbrain dopamine neurons: Are they mediated by formation of a neurotensin—dopamine complex?

1991 • 26 citations

Release of cholecystokinin from rat midbrain slices and modulatory effect of D2 DA receptor stimulation

1991 • 25 citations

Cellular localization of tyrosine hydroxylase mRNA and cholecystokinin mRNA-containing cells in the ventral mesencephalon of the common marmoset: effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1992 • 25 citations

Electrophysiological evidence for a non-opioid interaction between dynorphin and GABA in the substantia nigra of the rat

1987 • 24 citations

Behavioral and pharmacological specificity of the feeding elicited by cholinergic stimulation of the substantia nigra in the rat.

1983 • 24 citations

Effects of intranigral substance p and neurokinin a on striatal dopamine release—II. Interactions with bicuculline and naloxone

1990 • 23 citations

Selective distribution of N-acetylasparthlglutamate immunoreactivity in the extrapyramidal system of the rat

1989 • 23 citations

Reduction in motor responding of the mouse by actions of dopamine agonists in the midbrain

1983 • 22 citations

Multiple opiate receptors may be involved in suppressing γ-aminobutyrate release in substantia nigra

1985 • 22 citations

Neurotensin and Neuromedin N Are Differently Metabolized in Ventral Tegmental Area and Nucleus Accumbens

1991 • 21 citations

Microinjection of the D2 agonist quinpirole into the A10 dopamine region blocks amphetamine-, but not cocaine-stimulated motor activity.

1992 • 21 citations

Substance P synaptic interactions with GABAergic and dopaminergic neurons in rat substantia nigra: An ultrastructural doublelabeling immunocytochemical study

1992 • 21 citations

Substantia nigra and motor control in the rat: effect of intranigral α-kainate and γ-d-glutamylaminomethylsulphonate on motility

1987 • 20 citations

The density of GABAB binding sites in the substantia nigra is greater in rat pups than in adults

1992 • 20 citations

Morphine-Induced Modification of the Functional Properties of Ventral Tegmental Area Neurons in Conscious Rat

1988 • 19 citations

Differential Effects of Tachykinins Injected Intranigrally on Striatal Dopamine Metabolism

1988 • 19 citations

Interactions Between the Argininyl Moieties of Neurotensin and the Catechol Protons of Dopamine

1991 • 19 citations

Application of acetylcholinesterase to the substantia nigra induces stereotypy in rats

1985 • 19 citations

Ultrastructural localization of enkephalin immunoreactivity in the substantia nigra of the monkey

1986 • 19 citations

Effect of Dopamine Agonists and Antagonists on DOPA Formation in the Substantia Nigra

1982 • 19 citations

Rotation following intranigral injections of a selective D1 or a selective D2 dopamine receptor agonist in rats

1988 • 19 citations

Psychopharmacological evidence for a role of the ATP-sensitive potassium channel in the substantia nigra of the rat

1991 • 18 citations

Receptor selectivity of cholecystokinin effects on mesoaccumbens dopamine neurons

1991 • 18 citations

Intranigral substance P stimulation of striatal dopamine release is inhibited by Spantide II: a new tachykinin antagonist without apparent neurotoxicity

1990 • 18 citations

Effects of intranigral injections of dopamine agonists and antagonists, glycine, muscimol and N- methyl-D,L-aspartate on locomotor activity

1984 • 17 citations

Substance K (NKA) increases tyrosine hydroxylase mRNA in cultured substantia nigra

1988 • 17 citations

Cholinergic modulation of [3H]dopamine release from dendrosomes of rat substantia nigra

1991 • 17 citations

Chapter 22 Primary cholinergic and indirect dopaminergic mediation of behavioural effects of nicotine

1989 • 17 citations

Effects of Intranigral Substance P and Neurokinin A Injections on Extracellular Dopamine Levels Measured with Microdialysis in the Striatum and Frontoparietal Cortex of Rats

1991 • 16 citations

Circling evoked by intranigral SKF 38393: A GABA-mediated D-1 response?

1989 • 16 citations

Lesion of dopamine mesolimbic neurons blocks behavioral effects induced by the endogenous enkephalins but not by a μ-opioid receptor agonist

1991 • 15 citations

Pertussis Toxin in the A10 Region Increases Dopamine Synthesis and Metabolism

1992 • 15 citations

Potassium ions play a role in the glycine-induced inhibition of rat substantia nigra zona compacta neurones

1988 • 15 citations

Involvement of the nigrotectal and nigrothalamic pathways in kappa opioid‐induced circling

1992 • 15 citations

Preprotachykinin Gene Expression in the Forebrain: Regulation by Dopaminea

1991 • 14 citations

Presence of cholecystokinin mRNA in dopamine cells in the ventral mesencephalon of a human with schizophrenia

1989 • 14 citations

Depletion in substance P- and neurokinin A-like immunoreactivity in substantia nigra after ibotenate-induced lesions of striatum

1987 • 14 citations

Intranigral injection of dynorphin in combination with substance P on striatal dopamine metabolism in the rat

1988 • 14 citations

Infusions of cholecystokinin octapeptide into the ventral tegmental area potentiate amphetamine conditioned place preferences

1989 • 13 citations

Effects of the local application of 3-PPP and sulpiride enantiomers into the nucleus accumbens or into the ventral tegmental area on rat locomotor activity: evidence for the functional importance of somatodendritic autoreceptors

1992 • 13 citations

Correlation between the discharge rate of non-dopamine neurons in substantia nigra and ventral tegmental area and the motor activity induced by apomorphine

1988 • 13 citations

Effects of the CCK-A receptor antagonist CR 1409 on the activity of rat midbrain dopamine neurons

1991 • 13 citations

[3H]Strychnine binding suggests glycine receptors in the ventral tegmental area of rat brain

1981 • 12 citations

Substance P-like immunoreactive fibres in the ventromedial mesencephalic tegmentum of rat

1988 • 12 citations

Cholecystokinin octapeptide potentiates the inhibitory response mediated by D2 dopamine receptors in slices of the ventral tegmental area of the brain in the rat

1990 • 12 citations

Enkephalin-containing nerve cell bodies in the substantia nigra of the rat: Demonstration by immunohistochemistry and in situ hybridization

1991 • 12 citations

Kappa opiate binding sites in the substantia nigra and bulbus olfactorius of the guinea pig as shown by in vitro autoradiography

1983 • 12 citations

Biochemical correlates of motor changes caused by the manipulation of dopamine function in the substantia nigra of the mouse

1985 • 11 citations

Changes in dopamine D1 and D2 receptor binding in the substantia nigra following intrastriatal injection of a retrograde neurotoxin (volkensin)

1992 • 11 citations

Inhibition of enkephalin metabolism and activation of mu- or delta-opioid receptors elicit opposite effects on reward and motility in the ventral mesencephalon

1992 • 10 citations

Heterogeneity of [3H]neurotensin binding: studies with dynorphin, L-156,903 and levocabastine

1988 • 10 citations

Purification, Reconstitution, and Cloning of an NMDA Receptor-Ion Channel Complex from Rat Brain Synaptic Membranes: Implications for Neurobiological Changes in Alcoholism

1992 • 10 citations

Oscillation of interspike interval length in substantia nigra dopamine neurons: Effects of nicotine and the dopaminergic D₂ agonist LY 163502 on electrophysiological activity

1992 • 9 citations

Inhibition by pertussis toxin of the soporific effects induced by stimulation of dopamine D2, autoreceptors in the ventral tegmental area in rats

1989 • 9 citations

DOPAMINERGIC MODULATION OF THE GABA RELEASE IN THE SUBSTANTIA-NIGRA RETICULATA

1991 • 8 citations

Investigations About a Direct Neurotensin‐Dopamine Interaction by Nuclear Magnetic Resonance Study, Synaptosomal Uptake of Dopamine, and Binding of Neurotensin to Its Receptors

1992 • 8 citations

Role of Dendritic Dopamine of the Substantia Nigra in the Modulation of Nigrocollicular γ‐Aminobutyric Acid Release: In Vivo Studies in the Rat

1991 • 7 citations

Changes in GABA content and turnover in discrete regions of rat brain after systemic administration of caerulein

1990 • 6 citations

Possible Transduction Mechanisms Mediating the Acute and Sensitized Response to Neurotensin in the Ventral Tegmental Areaa

1992 • 5 citations

Amino Acid Transmitters

1990 • 4 citations

Recent Advances in the Biochemical Pharmacology of Extrapyramidal Movement Disorders

1977 • 2 citations