Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease

The Importance of Diagnostic Cytogenetics on Outcome in AML: Analysis of 1,612 Patients Entered Into the MRC AML 10 Trial

1998 • 2,668 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

1996 • 1,885 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

Chronic Myeloid Leukemia

1999 • 1,639 citations

Chromosomal translocations in human cancer

1994 • 1,551 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1982 • 1,385 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

1990 • 1,349 citations

Oncogenic Transcription Factors in the Human Acute Leukemias

1997 • 1,227 citations

Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

1994 • 1,211 citations

Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood

1998 • 968 citations

The Molecular Genetics of Philadelphia Chromosome–Positive Leukemias

1988 • 867 citations

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1992 • 850 citations

Clinical Significance of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia

1998 • 772 citations

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

1993 • 760 citations

The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype [editorial; comment]

1996 • 739 citations

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.

1995 • 738 citations

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all

1990 • 726 citations

Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype.

1998 • 699 citations

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1990 • 692 citations

Molecular Analysis of Acute Promyelocytic Leukemia Breakpoint Cluster Region on Chromosome 17

1990 • 650 citations

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1992 • 582 citations

TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis.

1995 • 566 citations

The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion

1995 • 563 citations

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

1993 • 523 citations

Acute promyelocytic leukemia: from genetics to treatment

1994 • 474 citations

Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemia

1998 • 467 citations

Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance [see comments]

1995 • 452 citations

Neutrophilic-chronic myeloid leukemia: a distinct disease with a specific molecular marker (BCR/ABL with C3/A2 junction) [see comments]

1996 • 390 citations

New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia

1984 • 365 citations

Identificaton of a translocation with quinacrine fluorescence in a patient with acute leukemia.

1973 • 363 citations

Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets Report of the BIOMED-1 CONCERTED ACTION: Investigation of minimal residual disease in acute leukemia

1999 • 356 citations

Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia.

1990 • 350 citations

The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein.

1990 • 347 citations

AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia

1995 • 346 citations

Unique Forms of the abl Tyrosine Kinase Distinguish Ph ¹ -Positive CML from Ph ¹ -Positive ALL

1987 • 344 citations

Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes

1998 • 339 citations

Incidence and Clinical Relevance of TEL/AML1 Fusion Genes in Children With Acute Lymphoblastic Leukemia Enrolled in the German and Italian Multicenter Therapy Trials

1997 • 326 citations

Early Detection of Relapse by Prospective Reverse Transcriptase-Polymerase Chain Reaction Analysis of the PML/RARα Fusion Gene in Patients With Acute Promyelocytic Leukemia Enrolled in the GIMEMA-AIEOP Multicenter “AIDA” Trial

1998 • 317 citations

Clinical Significance of Cytogenetic Abnormalities in Adult Acute Lymphoblastic Leukemia

1998 • 313 citations

Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in 346 patients

1995 • 310 citations

Chromosomal abnormalities identify high-risk and low-risk patients with acute lymphoblastic leukemia

1986 • 308 citations

TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia

1996 • 306 citations

Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome

1993 • 294 citations

Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation

1991 • 288 citations

Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript.

1989 • 285 citations

Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study (8762)

1992 • 276 citations

Immunophenotyping Investigation of Minimal Residual Disease Is a Useful Approach for Predicting Relapse in Acute Myeloid Leukemia Patients

1997 • 271 citations

Alternative splicing and genomic structure of theAML1gene involved in acute myeloid leukemia

1995 • 269 citations

Clinical significance of cytogenetics in acute myeloid leukemia.

1997 • 267 citations

Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): a Pediatric Oncology Group study

1990 • 264 citations

The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia

1996 • 258 citations

Philadelphia positive acute lymphoblastic leukemia in adults: age distribution, BCR breakpoint and prognostic significance.

1991 • 251 citations

Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real‐time quantitative RT‐PCR

1998 • 247 citations

Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by the polymerase chain reaction

1991 • 247 citations

Flow cytometric analysis of normal B cell differentiation: a frame of reference for the detection of minimal residual disease in precursor-B-ALL

1999 • 237 citations

Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.

1993 • 231 citations

Biology and treatment of infant leukemias.

1995 • 231 citations

The Partner Gene of AML1 in t(16;21) Myeloid Malignancies Is a Novel Member of the MTG8(ETO) Family

1998 • 226 citations

The biology and treatment of acute lymphoblastic leukemia in adults

1995 • 220 citations

Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia [see comments]

1995 • 220 citations

ALL-1 partial duplication in acute leukemia.

1994 • 219 citations

Genetic Diagnosis and Molecular Monitoring in the Management of Acute Promyelocytic Leukemia

1999 • 219 citations

Sequence and Analysis of the Human ABL Gene, the BCR Gene, and Regions Involved in the Philadelphia Chromosomal Translocation

1995 • 215 citations

Detection of bcr-abl Transcripts in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia After Marrow Transplantation

1997 • 212 citations

Pre-B cell leukemia associated with chromosome translocation 1;19

1984 • 203 citations

The SCL Gene: From Case Report to Critical Hematopoietic Regulator

1999 • 194 citations

Immunophenotypic and Genotypic Features,Clinical Characteristics,and Treatment Outcome of Adult Pro-B acute Lymphoblastic Leukemia:Results of the German Multicenter Trials GMALL 03/87 and 04/89

1998 • 193 citations

Cytogenetics of pre-B-cell acute lymphoblastic leukemia with emphasis on prognostic implications of the t(1;19).

1990 • 188 citations

Frequency and prognostic significance of HRX rearrangements in infant acute lymphoblastic leukemia: a Pediatric Oncology Group study

1994 • 183 citations

Quantification of residual disease in chronic myelogenous leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction

1996 • 178 citations

Therapy-related acute myeloid leukemia with t(8;21), inv(16), and t(8;16): a report on 25 cases and review of the literature.

1993 • 178 citations

Molecular monitoring of the myl/retinoic acid receptor-alpha fusion gene in acute promyelocytic leukemia by polymerase chain reaction

1992 • 173 citations

TEL-AML1 Fusion Transcript in Relapsed Childhood Acute Lymphoblastic Leukemia

1998 • 171 citations

Incidence of TEL/AML1 Fusion Gene Analyzed Consecutively in Children With Acute Lymphoblastic Leukemia in Relapse

1997 • 169 citations

Detection of fusion transcripts generated by the inversion 16 chromosome in acute myelogenous leukemia

1994 • 168 citations

Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin.

1984 • 168 citations

Detection of minimal residual disease in patients with AML1/ETO-associated acute myeloid leukemia using a novel quantitative reverse transcription polymerase chain reaction assay

1998 • 168 citations

Molecular Cloning of Translocation t(1;14)(q21;q32) Defines a Novel Gene (BCL9) at Chromosome 1q21

1998 • 163 citations

Human homologue of the rat chondroitin sulfate proteoglycan, NG2, detected by monoclonal antibody 7.1, identifies childhood acute lymphoblastic leukemias with t(4;11)(q21;q23) or t(11;19)(q23;p13) and MLL gene rearrangements

1996 • 158 citations

Persistence of the AML1/ETO fusion transcript in patients treated with allogeneic bone marrow transplantation for t(8;21) leukemia

1996 • 157 citations

Hematologic malignancies with t(4;11)(q21;q23) – a cytogenetic, morphologic, immunophenotypic and clinical study of 183 cases

1998 • 154 citations

p190 BCR-ABL mRNA is expressed at low levels in p210-positive chronic myeloid and acute lymphoblastic leukemias

1996 • 151 citations

P190BCR-ABL chronic myeloid leukaemia: the missing link with chronic myelomonocytic leukaemia?

1994 • 147 citations

Marrow Transplants From Unrelated Donors for Treatment of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

1997 • 144 citations

Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL). A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92.

1996 • 140 citations

Involvement of the putative hematopoietic transcription factor SCL in T- cell acute lymphoblastic leukemia

1992 • 140 citations

Molecular detection of t(8;21)/AML1‐ETO in AML M1/M2: correlation with cytogenetics, morphology and immunophenotype

1996 • 135 citations

Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.

1993 • 134 citations

Two site-specific deletions and t(1;14) translocation restricted to human T-cell acute leukemias disrupt the 5' part of the tal-1 gene.

1991 • 133 citations

Exon/intron structure of the human ALL‐1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias

1996 • 133 citations

Ten novel 11q23 chromosomal partner sites

1998 • 131 citations

Analysis of molecular breakpoint and m‐RNA transcripts in a prospective randomized trial of interferon in chronic myeloid leukaemia: no correlation with clinical features, cytogenetic response, duration of chronic phase, or survival

1995 • 129 citations

Early detection of relapse after bone marrow transplantation in patients with chronic myelogenous leukaemia

1993 • 129 citations

Predictability of the t(1;19)(q23;p13) from surface antigen phenotype: implications for screening cases of childhood acute lymphoblastic leukemia for molecular analysis: a Pediatric Oncology Group study

1993 • 128 citations

Incidence of TEL/AML1 Fusion in Children With Relapsed Acute Lymphoblastic Leukemia

1998 • 126 citations

CBFA2(AML1) Translocations With Novel Partner Chromosomes in Myeloid Leukemias: Association With Prior Therapy

1998 • 126 citations

A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias

1993 • 122 citations

Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: a Pediatric Oncology Group study

1993 • 118 citations

Genomic organization of TEL: the human ETS-variant gene 6.

1996 • 114 citations

Detection of the chromosome 16 CBF beta-MYH11 fusion transcript in myelomonocytic leukemias

1995 • 114 citations

Hematological malignancies with t(9;11)(p21–22;q23) – a laboratory and clinical study of 125 cases

1998 • 114 citations

Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia.

1991 • 113 citations

Partial Tandem Duplications of the MLL Gene Are Detectable in Peripheral Blood and Bone Marrow of Nearly All Healthy Donors

1998 • 112 citations

The translocations, t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3): a cytogenetic and clinical profile of 53 patients

1998 • 110 citations

ETV6 is the target of chromosome 12p deletions in t(12;21) childhood acute lymphocytic leukemia

1997 • 109 citations

Detection of ALL-1/AF4 fusion transcript by reverse transcription- polymerase chain reaction for diagnosis and monitoring of acute leukemias with the t(4;11) translocation

1993 • 108 citations

Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials

1997 • 107 citations

Secondary acute leukemia and myelodysplastic syndrome with 11q23 abnormalities

1998 • 107 citations

Consistent amounts of acute leukemia-associated P190BCR/ABL transcripts are expressed by chronic myelogenous leukemia patients at diagnosis

1996 • 106 citations

Heterogeneity in CBF beta/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia

1995 • 106 citations

DETECTION OF RESIDUAL bcr/abl TRANSLOCATION BY POLYMERASE CHAIN REACTION IN CHRONIC MYELOID LEUKAEMIA PATIENTS AFTER BONE-MARROW TRANSPLANTATION

1989 • 106 citations

Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: prognostic implications

1994 • 105 citations

Genetic studies of childhood acute lymphoblastic leukemia with emphasis on p16, MLL, and ETV6 gene abnormalities: results of St Jude Total Therapy Study XII

1997 • 102 citations

Detection of CBFB/MYH11 transcripts in patients with inversion and other abnormalities of chromosome 16 at presentation and remission

1995 • 96 citations

Biologic heterogeneity in Philadelphia chromosome-positive acute leukemia with myeloid morphology: the Eastern Cooperative Oncology Group experience

1998 • 93 citations

Exon/intron structure of the human AF‐4 gene, a member of the AF‐4/LAF‐4/FMR‐2 gene family coding for a nuclear protein with structural alterations in acute leukaemia

1997 • 93 citations

Frequency of CBFβ/MYH11 fusion transcripts in patients entered into the U.K. MRC AML trials

1997 • 93 citations

Molecular characterization of 16p deletions associated with inversion 16 defines the critical fusion for leukemogenesis

1995 • 91 citations

Expression of c-abl in Philadelphia-positive acute myelogenous leukemia

1987 • 89 citations

TEL-AML1 fusion RNA as a new target to detect minimal residual disease in pediatric B-cell precursor acute lymphoblastic leukemia

1996 • 86 citations

Bone Marrow Transplantation for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

1997 • 86 citations

The t(6;11)(q27;q23) translocation in acute leukemia: a laboratory and clinical study of 30 cases

1998 • 86 citations

Recurrent chromosomal translocations and fusion genes in leukemia-lymphoma cell lines.

1995 • 85 citations

Good correlation between RT-PCR analysis and relapse in Philadelphia (Ph1)-positive acute lymphoblastic leukemia (ALL)

1997 • 84 citations

Molecular detection of minimal residual disease in adult and childhood acute lymphoblastic leukaemia reveals differences in treatment response

1997 • 83 citations

Bone marrow transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia.

1996 • 76 citations

TEL/AML1 fusion gene is a rare event in adult acute lymphoblastic leukemia.

1996 • 76 citations

Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus

1997 • 73 citations

Cloning and characterization of the T(15;17) translocation breakpoint region in acute promyelocytic leukemia

1990 • 71 citations

TEL/AML1 positivity in childhood ALL: average or better prognosis?

1999 • 68 citations

RT-PCR diagnosis of patients with acute nonlymphocytic leukemia and inv(16)(p13q22) and identification of new alternative splicing in CBFB- MYH11 transcripts

1995 • 67 citations

Detection of CBFβ/MYH11 fusion transcripts in patients with inv(16) acute myeloid leukemia after allogeneic bone marrow or peripheral blood progenitor cell transplantation

1998 • 67 citations

Translocation 1;19—A new cytogenetic abnormality in acute lymphocytic leukemia

1984 • 67 citations

The t(10;11)(p12;q23) translocation in acute leukaemia: a cytogenetic and clinical study of 20 patients

1998 • 67 citations

Detection of BCR-ABL fusion genes in adult acute lymphoblastic leukemia by the polymerase chain reaction.

1994 • 66 citations

Molecular cytogenetics of childhood hematological malignancies

1997 • 65 citations

Chronic myeloid leukemia may be associated with several bcr-abl transcripts including the acute lymphoid leukemia-type 7 kb transcript [see comments]

1990 • 65 citations

Detection of minimal residual disease in acute leukemia patients.

1996 • 63 citations

Expression of CD25 (interleukin-2 receptor α chain) in adult acute lymphoblastic leukemia predicts for the presence of BCR/ABL fusion transcripts: results of a preliminary laboratory analysis of ECOG/MRC Intergroup Study E2993

1997 • 60 citations

Competitive CBFbeta/MYH11 reverse-transcriptase polymerase chain reaction for quantitative assessment of minimal residual disease during postremission therapy in acute myeloid leukemia with inversion(16): a pilot study.

1998 • 59 citations

The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.

1997 • 56 citations

Underestimation of inversion (16) in acute myeloid leukaemia using standard cytogenetics as compared with polymerase chain reaction: results of a prospective investigation

1997 • 55 citations

Establishment and characterization of a new human leukemia cell line derived from M4E0

1991 • 54 citations

tal-1 deletions in T-cell acute lymphoblastic leukemia as PCR target for detection of minimal residual disease.

1993 • 54 citations

Characterization of the blast cells in acute leukemia with translocation (4;11): report of eight additional cases and of one case with a variant translocation.

1987 • 53 citations

Lack of correlation between ABL‐BCR expression and response to interferon‐α in chronic myeloid leukaemia

1996 • 53 citations

A specific deletion in the breakpoint cluster region of the ALL-1 gene is associated with acute lymphoblastic T-cell leukemias.

1996 • 50 citations

Commentary on and reprint of Rowley JD, A new consistent abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining, in Nature (1973) 243:290–293

2000 • 47 citations

Clinical relevance of residual disease monitoring by polymerase chain reaction in patients with ALL‐1/AF‐4 positive‐acute lymphoblastic leukaemia

1996 • 47 citations

Distinct patterns of minimal residual disease associated with graft-versus-host disease after allogeneic bone marrow transplantation for chronic myelogenous leukemia.

1995 • 44 citations

Comparison of karyotype analysis and RT-PCR for AML1/ETO in 204 unselected patients with AML

1998 • 42 citations

Detection and quantitation of the CBFβ/MYH11 transcripts associated with the inv(16) in presentation and follow-up samples from patients with AML

1997 • 42 citations

MLL Genomic Breakpoint Distribution Within the Breakpoint Cluster Region in De Novo Leukemia in Children

1998 • 42 citations

Simultaneous SIL‐TAL1 RT‐PCR detection of all tal^d deletions and identification of novel tal^d variants

1997 • 41 citations

Detection of HRX-FEL fusion transcripts in pre-pre-B-ALL with and without cytogenetic demonstration of t(4;11).

1994 • 40 citations

Detection of CBFβ/MYH11 fusion transcripts in acute myeloid leukemia: heterogeneity of cytological and molecular characteristics

1997 • 40 citations

Prognosis Value of Residual Disease Monitoring by Polymerase Chain Reaction in Patients With CBFβ/MYH11-Positive Acute Myeloblastic Leukemia

1997 • 38 citations

Philadelphia chromosome‐negative chronic myeloid leukaemia: a report of 14 new cases

1995 • 34 citations

Molecular Diagnosis and Clinical Relevance of t(9;22), t(4;ll) and t(l;19) Chromosome Abnormalities in a Consecutive Group of 141 Adult Patients with Acute Lymphoblastic Leukemia

1996 • 33 citations

Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative (8) chromosome in the t(8;21) of acute myeloid leukemia M2

1994 • 30 citations

Value of PCR analysis for long term survivors after allogeneic bone marrow transplant for chronic myelogenous leukemia: a comparative study

1996 • 28 citations

Defining the “Absence” of the CBFβ/MYH11 Fusion Transcript in Patients With Acute Myeloid Leukemia and Inversion of Chromosome 16 to Predict Long-Term Complete Remission: A Call for Definitions

1997 • 28 citations

Unexpected heterogeneity in E2A/PBX1 fusion messenger RNA detected by the polymerase chain reaction in pediatric patients with acute lymphoblastic leukemia

1992 • 28 citations

Acquisition of the Ph chromosome and BCR-ABL fusion product in AML-M2 and t(8;21) leukemia: cytogenetic and FISH evidence for a late event

1998 • 25 citations

TAL1 expression does not occur in the majority of T‐ALL blasts

1998 • 21 citations

Molecular diversity in AML1/ETO fusion transcripts in patients with t(8;21) positive acute myeloid leukaemia.

1994 • 20 citations

Molecular diagnosis and monitoring of acute myeloid leukemia

1996 • 20 citations

Detection of recurrent translocations using real time PCR; assessment of the technique for diagnosis and detection of minimal residual disease.

1999 • 19 citations

Detection of AML1/ETO Fusion Transcripts in Patients With t(8; 21) Acute Myeloid Leukemia After Allogeneic Bone Marrow Transplantation or Peripheral Blood Progenitor Cell Transplantation

1997 • 19 citations

t(8;20)(q22;p13): a novel variant translocation of t(8;21) in acute myeloblastic leukaemia

1997 • 18 citations

Low incidence of TAL1 gene rearrangements in adult acute lymphoblastic leukemia: A cancer and leukemia group B study (8762)

1995 • 17 citations

Secondary acute myeloid leukemia with translocation (4;11) and MLL/AF4 rearrangement in a 15-year-old boy treated for common acute lymphoblastic leukemia 11 years earlier

1995 • 10 citations

Three cases of the myelodysplastic syndrome with pericentric inversion of chromosome 16

1993 • 9 citations

Lack of ETV6 (TEL) gene rearrangements or p16INK4A/p15INK4B homozygous gene deletions in infant acute lymphoblastic leukemia

1997 • 8 citations

Chronic myelogenous leukemia: too much or too little growth, or both?

1998 • 7 citations

Deleted Work

1955 • 0 citations