Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Basic local alignment search tool

1990 • 87,358 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Methods in yeast genetics

1979 • 7,824 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

1991 • 897 citations

Construction and characterization of a yeast artificial chromosome library containing seven haploid human genome equivalents.

1990 • 408 citations

Acceleration of nucleic acid hybridization rate by polyethylene glycol

1986 • 383 citations

Identification of the Constant Chromosome Regions Involved in Human Hematologic Malignant Disease

1982 • 309 citations

The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system.

1990 • 299 citations

Translocations, master genes, and differences between the origins of acute and chronic leukemias

1991 • 286 citations

8;21 translocation in acute granulocytic leukaemia: cytological, cytochemical and clinical features

1984 • 248 citations

Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions.

1990 • 187 citations

Accumulation of collagen III at the cleft points of developing mouse submandibular epithelium

1988 • 181 citations

Associations between morphology, karyotype, and clinical features in myeloid leukemias

1987 • 154 citations

The Drosophila segmentation gene runt acts as a position-specific numerator element necessary for the uniform expression of the sex-determining gene Sex-lethal.

1991 • 139 citations

Clinical implications of aneuploid cyto genetic profiles in adult acute leukemia

1974 • 87 citations

8-21 TRANSLOCATION AND MISSING SEX CHROMOSOMES IN ACUTE LEUKqMIA

1974 • 84 citations

Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: evidence that c-mos is not translocated.

1985 • 61 citations

Conversion of bovine cardiac adenosine cyclic 3',5'-phosphate dependent protein kinase to a heterodimer by removal of 45 residues at the N-terminus of the regulatory subunit

1986 • 50 citations

In vitro differentiation of leukemic cells to eosinophils in the presence of interleukin-5 in two cases of acute myeloid leukemia with the translocation (8;21)(q22;q22)

1990 • 45 citations

Acute myeloid leukemias with chromosomal abnormalities involving the 21q22 region identified by their in vitro responsiveness to interleukin-5.

1991 • 34 citations