Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

1982 • 755 citations

Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining

1989 • 572 citations

V(D)J recombination: a functional definition of the joining signals.

1989 • 467 citations

V(D)J Recombination: Molecular Biology and Regulation

1992 • 464 citations

The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.

1989 • 363 citations

Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia.

1990 • 350 citations

The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein.

1990 • 347 citations

Disruption of the Human SCL Locus by "Illegitimate" V-(D)-J Recombinase Activity

1990 • 301 citations

Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript.

1989 • 285 citations

The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15.

1988 • 236 citations

Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.

1989 • 227 citations

Two Pairs of Recombination Signals Are Sufficient to Cause Immunoglobulin V-(D)-J Joining

1987 • 222 citations

Analysis of immunoglobulin and T cell receptor genes. Part I: Basic and technical aspects

1991 • 214 citations

A Common Mechanism of Chromosomal Translocation in T- and B-Cell Neoplasia

1986 • 205 citations

bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia

1986 • 186 citations

Deletion of the human T-cell receptor δ-gene by a site-specific recombination

1988 • 179 citations

Differential expression of the LYL, SCL and E2A helix-loop-helix genes within the hemopoietic system.

1991 • 161 citations

Enhancer-Binding Activity of the tal-1 Oncoprotein in Association with the E47/E12 Helix-Loop-Helix Proteins

1991 • 156 citations

SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain.

1992 • 148 citations

Chromosomal translocations in lymphoid neoplasia: a reappraisal of the recombinase model.

1990 • 143 citations

Involvement of the putative hematopoietic transcription factor SCL in T- cell acute lymphoblastic leukemia

1992 • 140 citations

Human T-cell-receptor delta chain: genomic organization, diversity, and expression in populations of cells.

1988 • 136 citations

Two site-specific deletions and t(1;14) translocation restricted to human T-cell acute leukemias disrupt the 5' part of the tal-1 gene.

1991 • 133 citations

Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T‐cell leukemias

1990 • 127 citations

V(D)J recombinase-like activity mediates hprt gene deletion in human fetal T-lymphocytes.

1991 • 124 citations

Human T cell gamma chain joining regions and T cell development.

1987 • 114 citations

Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia.

1991 • 113 citations

Erythroid expression of the 'helix-loop-helix' gene, SCL.

1991 • 106 citations

Complex rearrangements within the human J delta-C delta/J alpha-C alpha locus and aberrant recombination between J alpha segments.

1988 • 105 citations

The SCL Gene Is Formed from a Transcriptionally Complex Locus

1990 • 101 citations

The t(1;14)(p34;q11) is nonrandom and restricted to T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study

1990 • 99 citations

Human T-cell antigen receptor (TCR) delta-chain locus and elements responsible for its deletion are within the TCR alpha-chain locus.

1988 • 93 citations

Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia.

1990 • 90 citations

In vivo hprt mutant frequencies in T-cells of normal human newborns

1990 • 77 citations

Development of human T lymphocytes and their thymus-dependency.

1990 • 70 citations

Molecular Characterization of the Lymphoid V(D) J Recombination Activity

1989 • 68 citations

The SCL gene is formed from a transcriptionally complex locus.

1990 • 63 citations

Disruption of the SCL locus in T-lymphoid malignancies correlates with commitment to the T-cell receptor alpha beta lineage

1992 • 56 citations

Molecular analyses of in vivo hprt mutations in human t‐lymphocytes: IV. Studies in Newborns

1989 • 47 citations

A chromosomal basis of lymphoid malignancy in man

1989 • 46 citations

A Novel Mechanism of Somatic Rearrangement Predicted by a Human T-Cell Antigen Receptor β-Chain Complementary DNA

1985 • 43 citations

Helix-loop-helix genes translocated in lymphoid leukemia

1991 • 41 citations

Structural Characterization of SIL, a Gene Frequently Disrupted in T-Cell Acute Lymphoblastic Leukemia

1991 • 28 citations

V (D) J Recombination: Molecular Biology And Regulation

1992 • 26 citations

Involvement of the putative hematopoietic transcription factor SCL in T- cell acute lymphoblastic leukemia

1992 • 16 citations

Extensive junctional diversity of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias: implications for the detection of minimal residual disease.

1991 • 13 citations

5.2 Receptor diversity of human T-cell receptor ?? expressing cells

1992 • 5 citations

The t(1;14)(p34;q11) is nonrandom and restricted to T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study

1990 • 3 citations

bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia

1986 • 3 citations

A chromosomal basis of lymphoid malignancy in man

1989 • 1 citations