RT-PCR diagnosis of patients with acute nonlymphocytic leukemia and inv(16)(p13q22) and identification of new alternative splicing in CBFB- MYH11 transcripts

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

1991 • 897 citations

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

1993 • 760 citations

Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support

1989 • 747 citations

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.

1993 • 621 citations

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1992 • 582 citations

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

1993 • 523 citations

Molecular Cloning and Characterization of PEBP2β, the Heterodimeric Partner of a Novel Drosophila runt-Related DNA Binding Protein PEBP2α

1993 • 504 citations

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.

1993 • 484 citations

Cloning and Characterization of Subunits of the T-Cell Receptor and Murine Leukemia Virus Enhancer Core-Binding Factor

1993 • 425 citations

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.

1994 • 335 citations

The runt domain identifies a new family of heterometric transcriptional regulators

1993 • 331 citations

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.

1994 • 315 citations

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations.

1994 • 272 citations

Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.

1993 • 229 citations

Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer

1990 • 218 citations

Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers.

1992 • 194 citations

The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1.

1993 • 179 citations

Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificity.

1990 • 178 citations

Detection of fusion transcripts generated by the inversion 16 chromosome in acute myelogenous leukemia

1994 • 168 citations

Multiple determinants of eukaryotic mRNA stability.

1989 • 118 citations

Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers.

1992 • 102 citations

Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele specific amplification

1994 • 84 citations

Human smooth muscle myosin heavy chain gene mapped to chromosomal region 16q12

1993 • 76 citations

Molecular genetic dissection of myosin heavy chain function

1990 • 73 citations

Differential Expression of Subspecies of Polyomavirus and Murine Leukemia Virus Enhancer Core Binding Protein, PEBP2, in Various Hematopoietic Cells

1992 • 46 citations

A gene for a myosin peptide is disrupted by the inv(16)(p13q22) in acute nonlymphocytic leukemia M4Eo

1993 • 35 citations

A tumor promoting phorbol ester, TPA, enhances polyomavirus DNA replication by activating the function of the viral enhancer.

1990 • 34 citations

Cosmid vector pCpG and plasmid vector pKNUNl, and their use for cloning DNA sequences adjacent to sites for rare cutting restriction endonucleases

1989 • 8 citations