Frequency and prognostic significance of HRX rearrangements in infant acute lymphoblastic leukemia: a Pediatric Oncology Group study

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

1977 • 8,468 citations

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1992 • 944 citations

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1992 • 850 citations

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

1991 • 602 citations

Clinical characteristics and treatment outcome of childhood acute lymphoblastic leukemia with the t(4;11)(q21;q23): a collaborative study of 40 cases [see comments]

1991 • 307 citations

Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.

1993 • 297 citations

Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome

1993 • 294 citations

Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) chromosome translocations.

1991 • 185 citations

HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities [see comments]

1993 • 166 citations

Clinical and biologic features predict a poor prognosis in acute lymphoid leukemias in infants: a Pediatric Oncology Group Study

1986 • 158 citations

Translocation 4; 11 in acute lymphoblastic leukemia: clinical characteristics and prognostic significance

1982 • 152 citations

An analysis of leukemic cell chromosomal features in infants

1987 • 148 citations

Clinical and laboratory characteristics of acute leukemia with the 4;11 translocation

1986 • 140 citations

A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias

1993 • 122 citations

ALL-1 gene at chromosome 11q23 is consistently altered in acute leukemia of early infancy

1993 • 115 citations

Clinical characteristics of infant acute leukemia with or without 11q23 translocations.

1988 • 109 citations

Childhood acute lymphoblastic leukemia with chromosomal breakpoints at 11q23

1989 • 107 citations

The t(1;14)(p34;q11) is nonrandom and restricted to T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study

1990 • 99 citations

Acute leukemias associated with the 4;11 chromosome translocation have rearranged immunoglobulin heavy chain genes

1985 • 74 citations

Infant acute lymphoblastic leukaemia with t(11;19)

1990 • 56 citations

An altered 11-kilobase transcript in leukemic cell lines with the t(4;11)(q21;q23) chromosome translocation.

1992 • 53 citations

Unfavorable presenting clinical and laboratory features are associated with calla-negative non-t, non-b lymphoblastic leukemia in children

1986 • 48 citations

Breakpoints at 11q23 in infant leukemias with the t(11;19)(q23;p13) are clustered

1992 • 43 citations

Breakpoint clustering in t(4;11)(q21;q23) acute leukemia

1991 • 43 citations