Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by the polymerase chain reaction

Avoiding false positives with PCR

1989 • 3,564 citations

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

Induction of Chronic Myelogenous Leukemia in Mice by the P210 ^bcr/abl Gene of the Philadelphia Chromosome

1990 • 2,207 citations

Tyrosine Kinase Activity and Transformation Potency of bcr-abl Oncogene Products

1990 • 1,305 citations

The Molecular Genetics of Philadelphia Chromosome–Positive Leukemias

1988 • 867 citations

Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.

1988 • 741 citations

Acute leukaemia in bcr/abl transgenic mice

1990 • 701 citations

Prognostic factors in a multicenter study for treatment of acute lymphoblastic leukemia in adults

1988 • 602 citations

Chromosomal abnormalities identify high-risk and low-risk patients with acute lymphoblastic leukemia

1986 • 308 citations

Die Corticosteroid-abhängige Dezimierung der Leukämiezellzahl im Blut als Prognosefaktor bei der akuten lymphoblastischen Leukämie im Kindesalter (Therapiestudie ALL-BFM 83)

1987 • 266 citations

Philadelphia chromosome positive childhood acute lymphoblastic leukemia: clinical and cytogenetic characteristics and treatment outcome. A Pediatric Oncology Group study

1990 • 228 citations

Results and Significance of Six Randomized Trials in Four Consecutive ALL-BFM Studies

1990 • 188 citations

bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia

1986 • 186 citations

Chromosomal translocations play a unique role in influencing prognosis in childhood acute lymphoblastic leukemia

1986 • 151 citations

Ambiguous phenotypes and genotypes in 16 children with acute leukemia as characterized by multiparameter analysis

1988 • 137 citations

Prethymic phenotype and genotype of pre-T (CD7+/ER-)-cell leukemia and its clinical significance within adult acute lymphoblastic leukemia [see comments]

1989 • 126 citations

Detection of two alternative bcr/abl mRNA junctions and minimal residual disease in Philadelphia chromosome positive chronic myelogenous leukemia by polymerase chain reaction

1989 • 117 citations

bcr-abl oncogene activation in Philadelphia chromosome-positive acute lymphoblastic leukemia.

1988 • 77 citations

Variable Philadelphia breakpoints and potential lineage restriction of bcr rearrangement in acute lymphoblastic leukemia

1988 • 61 citations

Philadelphia-positive acute leukemia

1990 • 40 citations

Rapid progress in chronic myelogenous leukemia.

1988 • 39 citations

Acute Leukemias II

1990 • 24 citations

Immunologic characterization of the tumor-specific bcr-abl junction in Philadelphia chromosome-positive acute lymphoblastic leukemia

1990 • 17 citations

Chromosomal alterations in the course of viral leukemogenesis in the rat

1981 • 6 citations