Immunophenotyping Investigation of Minimal Residual Disease Is a Useful Approach for Predicting Relapse in Acute Myeloid Leukemia Patients

Report of the National Cancer Institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia.

1990 • 813 citations

Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance [see comments]

1995 • 452 citations

Outcome prediction in childhood acute lymphoblastic leukaemia by molecular quantification of residual disease at the end of induction

1994 • 276 citations

Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia

1992 • 241 citations

Correlation of multidrug resistance (MDR1) protein expression with functional dye/drug efflux in acute myeloid leukemia by multiparameter flow cytometry: identification of discordant MDR-/efflux+ and MDR1+/efflux- cases

1995 • 229 citations

Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia

1996 • 203 citations

Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: implications for the detection of minimal residual disease by polymerase chain reaction analysis

1994 • 176 citations

Flow cytometric characterization of acute myeloid leukemia. Part II. Phenotypic heterogeneity at diagnosis.

1992 • 170 citations

Expression of unusual immunophenotype combinations in acute myelogenous leukemia

1993 • 168 citations

Expression of unusual immunophenotype combinations in acute myelogenous leukemia

1993 • 148 citations

Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia

1996 • 116 citations

Significantly lower P-glycoprotein expression in acute promyelocytic leukemia than in other types of acute myeloid leukemia: immunological, molecular and functional analyses.

1994 • 108 citations

Prediction of Relapse of Pediatric Acute Myeloid Leukemia by Use of Multidimensional Flow Cytometry

1996 • 87 citations

Flow cytometric determination of atypical antigen expression in acute leukemia for the study of minimal residual disease

1992 • 79 citations

Immunological detection of blast cell subpopulations in acute myeloblastic leukemia at diagnosis: implications for minimal residual disease studies.

1995 • 77 citations

Phenotypic analysis of CD34 subpopulations in normal human bone marrow and its application for the detection of minimal residual disease.

1995 • 74 citations

Increased light scattering resolution facilitates multidimensional flow cytometric analysis

1990 • 66 citations

Expression of P-glycoprotein in de novo acute myelogenous leukemia at initial diagnosis: results of molecular and functional assays, and correlation with treatment outcome.

1994 • 63 citations

N-CAM (CD56) expression by CD34+ malignant myeloblasts has implications for minimal residual disease detection in acute myeloid leukemia.

1993 • 59 citations

Multi-drug resistance (MDR) activity in acute leukemia determined by rhodamine 123 efflux assay.

1995 • 59 citations

Immunophenotype of c‐kit cells in normal human bone marrow: implications for the detection of minimal residual disease in AML

1995 • 44 citations

Detection of residual disease in AML patients by use of double immunological marker analysis for terminal deoxynucleotidyl transferase and myeloid markers.

1993 • 41 citations

Low frequency of activity of P-glycoprotein (P-170) in acute lymphoblastic leukemia compared to acute myeloid leukemia.

1995 • 23 citations

Streptavidin‐tricolor is a reliable marker for nonviable cells subjected to permeabilization or fixation

1994 • 18 citations

Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: implications for the detection of minimal residual disease by polymerase chain reaction analysis

1994 • 10 citations