Cross-Talk Among Integrin, Cadherin, and Growth Factor Receptor: Roles of Nectin and Nectin-Like Molecule

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

1963 • 3,559 citations

Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis

1996 • 3,454 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

Occludin: a novel integral membrane protein localizing at tight junctions.

1993 • 2,466 citations

Multifunctional strands in tight junctions

2001 • 2,392 citations

Transmembrane crosstalk between the extracellular matrix and the cytoskeleton

2001 • 2,141 citations

Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

1998 • 2,005 citations

Annexins: From Structure to Function

2002 • 1,942 citations

The Gap Junction Communication Channel

1996 • 1,896 citations

Cell Death in Development

1999 • 1,567 citations

Regulation of cadherin-mediated adhesion in morphogenesis

2005 • 1,475 citations

Morphogenetic roles of classic cadherins

1995 • 1,468 citations

Focal adhesion kinase: the first ten years

2003 • 1,360 citations

Junctional Adhesion Molecule, a Novel Member of the Immunoglobulin Superfamily That Distributes at Intercellular Junctions and Modulates Monocyte Transmigration

1998 • 1,356 citations

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

2003 • 1,168 citations

Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling

2002 • 1,134 citations

Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg ²⁺ Resorption

1999 • 1,107 citations

Cellular receptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily

1989 • 1,086 citations

Anchorage dependence, integrins, and apoptosis

1994 • 1,016 citations

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

1994 • 949 citations

A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts

1998 • 923 citations

Entry of Alphaherpesviruses Mediated by Poliovirus Receptor-Related Protein 1 and Poliovirus Receptor

1998 • 905 citations

Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.

1996 • 849 citations

Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

2003 • 824 citations

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

2002 • 817 citations

The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex.

1988 • 810 citations

Cadherin-catenin complex: Protein interactions and their implications for cadherin function

1996 • 806 citations

Endothelial Claudin

1999 • 802 citations

MOLECULAR AND FUNCTIONAL ANALYSIS OF CADHERIN-BASED ADHERENS JUNCTIONS

1997 • 800 citations

ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation

2006 • 764 citations

sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways

1998 • 745 citations

Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

2005 • 733 citations

Sticky Business

2003 • 709 citations

The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction

2001 • 685 citations

CNS Myelin and Sertoli Cell Tight Junction Strands Are Absent in Osp/Claudin-11 Null Mice

1999 • 678 citations

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity

2000 • 640 citations

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion

2003 • 631 citations

NEW EMBO MEMBER'S REVIEW: Role of integrins in regulating epidermal adhesion, growth and differentiation

2002 • 616 citations

Multi‐faceted regulation of cell differentiation by extracellular matrix

1993 • 610 citations

Neuronal Cell Death

1998 • 593 citations

Nectin and afadin: novel organizers of intercellular junctions

2002 • 574 citations

Herpesvirus Entry: an Update

2003 • 570 citations

Integrins: roles in cancer development and as treatment targets

2004 • 568 citations

Cell Junction Dynamics in the Testis: Sertoli-Germ Cell Interactions and Male Contraceptive Development

2002 • 558 citations

Assembly and mechanosensory function of focal contacts

2001 • 548 citations

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

2002 • 539 citations

Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions

1998 • 532 citations

Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut

2001 • 532 citations

Nectin/PRR: An Immunoglobulin-like Cell Adhesion Molecule Recruited to Cadherin-based Adherens Junctions through Interaction with Afadin, a PDZ Domain–containing Protein

1999 • 527 citations

Human junction adhesion molecule regulates tight junction resealing in epithelia

2000 • 521 citations

A Cell Surface Protein with Herpesvirus Entry Activity (HveB) Confers Susceptibility to Infection by Mutants of Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2, and Pseudorabies Virus

1998 • 497 citations

Observations on the social behaviour of cells in tissue culture

1953 • 492 citations

Junctional adhesion molecules (JAMs): more molecules with dual functions?

2003 • 483 citations

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

2003 • 476 citations

Afadin: A Novel Actin Filament–binding Protein with One PDZ Domain Localized at Cadherin-based Cell-to-Cell Adherens Junction

1997 • 473 citations

Differential Expression Patterns of Claudins, Tight Junction Membrane Proteins, in Mouse Nephron Segments

2002 • 453 citations

Molecular Physiology and Pathophysiology of Tight Junctions I. Tight junction structure and function: lessons from mutant animals and proteins

2000 • 439 citations

TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer

2001 • 438 citations

Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions

2002 • 436 citations

Claudin-11/OSP-based Tight Junctions of Myelin Sheaths in Brain and Sertoli Cells in Testis

1999 • 434 citations

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1γ by the FERM domain of talin

2002 • 432 citations

Freeze-fracture replica electron microscopy combined with sds digestion for cytochemical labeling of integral membrane proteins: Application to the immunogold labeling of intercellular junctional complexes

1995 • 430 citations

The p120 catenin family: Complex roles in adhesion, signaling and cancer

2000 • 427 citations

Intercellular junctions and cellular polarity: the PAR–aPKC complex, a conserved core cassette playing fundamental roles in cell polarity

2001 • 421 citations

Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line.

1994 • 405 citations

Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells

1995 • 393 citations

The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)

2001 • 387 citations

Integrin activation

2004 • 387 citations

Assembly of the tight junction: the role of diacylglycerol.

1993 • 381 citations

Junctional adhesion molecule (JAM) binds to PAR-3

2001 • 379 citations

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl

2003 • 368 citations

Modulation of signalling by Sprouty: a developing story

2004 • 357 citations

Claudin-based barrier in simple and stratified cellular sheets

2002 • 355 citations

Spatio-Temporal Regulation of Rac1 Localization and Lamellipodia Dynamics during Epithelial Cell-Cell Adhesion

2002 • 349 citations

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

2003 • 346 citations

Nectins and nectin‐like molecules: Roles in cell adhesion, migration, and polarization

2003 • 342 citations

Cutting Edge: CD96 (Tactile) Promotes NK Cell-Target Cell Adhesion by Interacting with the Poliovirus Receptor (CD155)

2004 • 333 citations

Poliovirus Cell Entry: Common Structural Themes in Viral Cell Entry Pathways

2002 • 332 citations

Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

2003 • 331 citations

Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia

2000 • 327 citations

The poliovirus receptor protein is produced both as membrane-bound and secreted forms.

1990 • 322 citations

Conformation, Localization, and Integrin Binding of Talin Depend on Its Interaction with Phosphoinositides

2001 • 316 citations

E-cadherin Homophilic Ligation Directly Signals through Rac and Phosphatidylinositol 3-Kinase to Regulate Adhesive Contacts

2002 • 315 citations

The structural basis of the blood-ocular barriers

1977 • 312 citations

Differential Roles of WAVE1 and WAVE2 in Dorsal and Peripheral Ruffle Formation for Fibroblast Cell Migration

2003 • 311 citations

Structural and signalling molecules come together at tight junctions

1999 • 306 citations

Tight Junctions: Molecular Architecture and Function

2006 • 306 citations

COOH Terminus of Occludin Is Required for Tight Junction Barrier Function in Early Xenopus Embryos

1997 • 301 citations

Nectin4/PRR4, a New Afadin-associated Member of the Nectin Family That Trans-interacts with Nectin1/PRR1 through V Domain Interaction

2001 • 298 citations

Tight junction formation in cultured epithelial cells (MDCK)

1985 • 298 citations

Direct cadherin-activated cell signaling

2002 • 285 citations

Afadin

1999 • 282 citations

Nectin

2002 • 281 citations

Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites

2001 • 276 citations

Nectin-3, a New Member of Immunoglobulin-like Cell Adhesion Molecules That Shows Homophilic and Heterophilic Cell-Cell Adhesion Activities

2000 • 275 citations

Adherens junction-dependent and -independent steps in the establishment of epithelial cell polarity in Drosophila

2004 • 272 citations

Lessons from Loricrin-Deficient Mice

2000 • 265 citations

Two Cell Adhesion Molecules, Nectin and Cadherin, Interact through Their Cytoplasmic Domain–Associated Proteins

2000 • 264 citations

Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation.

1993 • 260 citations

Overexpression of the CD155 gene in human colorectal carcinoma

2001 • 259 citations

Interactions between growth factor receptors and adhesion molecules: breaking the rules

2003 • 250 citations

Nectin Couples Cell-Cell Adhesion and the Actin Scaffold at Heterotypic Testicular Junctions

2002 • 247 citations

Depletion of E-Cadherin Disrupts Establishment but Not Maintenance of Cell Junctions in Madin-Darby Canine Kidney Epithelial Cells

2006 • 246 citations

Establishment and Characterization of Cultured Epithelial Cells Lacking Expression of ZO-1

2004 • 246 citations

Mammalian Sprouty Proteins Inhibit Cell Growth and Differentiation by Preventing Ras Activation

2001 • 246 citations

Ponsin/SH3P12: An l-Afadin– and Vinculin-binding Protein Localized at Cell–Cell and Cell–Matrix Adherens Junctions

1999 • 244 citations

JAM-2, a Novel Immunoglobulin Superfamily Molecule, Expressed by Endothelial and Lymphatic Cells

2001 • 242 citations

Vascular Endothelial Junction-associated Molecule, a Novel Member of the Immunoglobulin Superfamily, Is Localized to Intercellular Boundaries of Endothelial Cells

2000 • 239 citations

Biochemical and Structural Definition of the l-Afadin- and Actin-binding Sites of α-Catenin

2002 • 236 citations

Cell proliferation and apoptosis

1999 • 235 citations

CD226 (DNAM-1) Is Involved in Lymphocyte Function–associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation

2003 • 232 citations

Roles played by a subset of integrin signaling molecules in cadherin-based cell–cell adhesion

2004 • 230 citations

Ras GTPases: integrins' friends or foes?

2003 • 227 citations

Implications of Nectin-like Molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in Cell-Cell Adhesion and Transmembrane Protein Localization in Epithelial Cells

2003 • 222 citations

Cloning of Human Junctional Adhesion Molecule 3 (JAM3) and Its Identification as the JAM2 Counter-receptor

2001 • 219 citations

CD155/PVR plays a key role in cell motility during tumor cell invasion and migration

2004 • 218 citations

A Transmembrane Tight Junction Protein Selectively Expressed on Endothelial Cells and Platelets

2002 • 217 citations

E-cadherin-mediated Cell-Cell Attachment Activates Cdc42

2000 • 214 citations

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

1998 • 202 citations

Mutation of PVRL1 is associated with sporadic, non-syndromic cleft lip/palate in northern Venezuela

2001 • 202 citations

The Junction-associated Protein AF-6 Interacts and Clusters with Specific Eph Receptor Tyrosine Kinases at Specialized Sites of Cell–Cell Contact in the Brain

1999 • 195 citations

Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells – regulation by Rho, Rac and Rab small G proteins

1999 • 191 citations

Dynamic cross‐talk between cells and the extracellular matrix in the testis

2004 • 189 citations

Cloning of an Immunoglobulin Family Adhesion Molecule Selectively Expressed by Endothelial Cells

2001 • 188 citations

The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM

2005 • 188 citations

The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene

1995 • 185 citations

Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

2004 • 184 citations

JAM4, a Junctional Cell Adhesion Molecule Interacting with a Tight Junction Protein, MAGI-1

2003 • 184 citations

Desmosomal cadherins

2002 • 183 citations

Direct Binding of Cell Polarity Protein PAR-3 to Cell-Cell Adhesion Molecule Nectin at Neuroepithelial Cells of Developing Mouse

2003 • 172 citations

Regulation of E-cadherin Endocytosis by Nectin through Afadin, Rap1, and p120ctn

2005 • 168 citations

The Human Poliovirus Receptor Related 2 Protein Is a New Hematopoietic/Endothelial Homophilic Adhesion Molecule

1998 • 164 citations

Complementary DNA characterization and chromosomal localization of a human gene related to the poliovirus receptor-encoding gene

1995 • 163 citations

Nectin-1α, an Immunoglobulin-like Receptor Involved in the Formation of Synapses, Is a Substrate for Presenilin/γ-Secretase-like Cleavage

2002 • 163 citations

A Novel Protein with Homology to the Junctional Adhesion Molecule

2000 • 157 citations

Ultrastructure and three-dimensional organization of synaptic glomeruli in rat somatosensory thalamus.

1974 • 156 citations

Cross Talk between Adhesion Molecules: Control of N-cadherin Activity by Intracellular Signals Elicited by β1 and β3 Integrins in Migrating Neural Crest Cells

1997 • 155 citations

Nectin-4, a New Serological Breast Cancer Marker, Is a Substrate for Tumor Necrosis Factor-α-converting Enzyme (TACE)/ADAM-17

2005 • 153 citations

Involvement of LMO7 in the Association of Two Cell-Cell Adhesion Molecules, Nectin and E-cadherin, through Afadin and α-Actinin in Epithelial Cells

2004 • 149 citations

Composition and function of PDZ protein complexes during cell polarization

2003 • 148 citations

Molecular cloning and expression of a murine homolog of the human poliovirus receptor gene

1992 • 144 citations

Early Loss of E-cadherin from Cell-Cell Contacts Is Involved in the Onset of Anoikis in Enterocytes

2004 • 142 citations

Involvement of the c-Src-Crk-C3G-Rap1 Signaling in the Nectin-induced Activation of Cdc42 and Formation of Adherens Junctions

2004 • 142 citations

Interaction of the Poliovirus Receptor CD155 with the Dynein Light Chain Tctex-1 and Its Implication for Poliovirus Pathogenesis

2002 • 142 citations

Regulation of the Assembly and Adhesion Activity of E-cadherin by Nectin and Afadin for the Formation of Adherens Junctions in Madin-Darby Canine Kidney Cells

2005 • 142 citations

Cell-Cell Contacts Prevent Anoikis in Primary Human Colonic Epithelial Cells

2006 • 140 citations

Vascular Endothelial-Junctional Adhesion Molecule (VE-JAM)/JAM 2 Interacts with T, NK, and Dendritic Cells Through JAM 3

2002 • 138 citations

Regulation of Endocytosis, Nuclear Translocation, and Signaling of Fibroblast Growth Factor Receptor 1 by E-Cadherin

2004 • 137 citations

Axon guidance at choice points

1998 • 136 citations

PECAM‐1 shedding during apoptosis generates a membrane‐anchored truncated molecule with unique signaling characteristics

2001 • 131 citations

Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes

2005 • 129 citations

"Search-and-Capture" of Microtubules through Plus-End-Binding Proteins (+TIPs)

2003 • 129 citations

Par Proteins: Partners in Polarization

2004 • 129 citations

Tage4/Nectin-like Molecule-5 Heterophilically trans-Interacts with Cell Adhesion Molecule Nectin-3 and Enhances Cell Migration

2003 • 128 citations

Tyrosine Phosphorylation of Sprouty Proteins Regulates Their Ability to Inhibit Growth Factor Signaling: A Dual Feedback Loop

2004 • 127 citations

Identification and molecular cloning of tactile. A novel human T cell activation antigen that is a member of the Ig gene superfamily.

1992 • 126 citations

Involvement of nectin in the localization of junctional adhesion molecule at tight junctions

2002 • 123 citations

Mouse Homolog of Poliovirus Receptor-Related Gene 2 Product, mPRR2, Mediates Homophilic Cell Aggregation

1997 • 123 citations

Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development

2005 • 113 citations

JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells

2003 • 113 citations

The Ras Target AF-6 is a Substrate of the Fam Deubiquitinating Enzyme

1998 • 111 citations

Interneurite affinity is regulated by heterophilic nectin interactions in concert with the cadherin machinery

2006 • 107 citations

Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions

2007 • 106 citations

Rho and Rab Small G Proteins Coordinately Reorganize Stress Fibers and Focal Adhesions in MDCK Cells

1998 • 106 citations

Enhancement of Serum- and Platelet-derived Growth Factor-induced Cell Proliferation by Necl-5/Tage4/Poliovirus Receptor/CD155 through the Ras-Raf-MEK-ERK Signaling

2004 • 105 citations

Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG

2004 • 104 citations

Nectin-like Molecule-5/Tage4 Enhances Cell Migration in an Integrin-dependent, Nectin-3-independent Manner

2004 • 104 citations

Inhibition of cell movement and proliferation by cell–cell contact-induced interaction of Necl-5 with nectin-3

2005 • 102 citations

Contact Inhibition in Colony Formation

1967 • 101 citations

A Novel Binding Protein Composed of Homophilic Tetramer Exhibits Unique Properties for the Small GTPase Rab5

2002 • 101 citations

Involvement of nectins in the formation of puncta adherentia junctions and the mossy fiber trajectory in the mouse hippocampus

2005 • 101 citations

ADIP, a Novel Afadin- and α-Actinin-Binding Protein Localized at Cell-Cell Adherens Junctions

2003 • 100 citations

A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets

1998 • 98 citations

Split personalities: the agonistic antagonist Sprouty

2003 • 93 citations

The Proximal Promoter of the Mouse Loricrin Gene Contains a Functional AP-1 Element and Directs Keratinocyte-specific but Not Differentiation-specific Expression

1995 • 92 citations

Mouse proximal tubular cell-cell adhesion inhibits apoptosis by a cadherin-dependent mechanism

2000 • 91 citations

Requirement of Interaction of Nectin-1α/HveC with Afadin for Efficient Cell-Cell Spread of Herpes Simplex Virus Type 1

2001 • 90 citations

Activation of Rac by cadherin through the c-Src–Rap1–phosphatidylinositol 3-kinase–Vav2 pathway

2005 • 90 citations

Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E‐cadherin‐based cell‐cell adhesion

2003 • 90 citations

Role of cell adhesion molecule nectin‐3 in spermatid development

2006 • 90 citations

Recruitment of Nectin-3 to Cell-Cell Junctions through trans-Heterophilic Interaction with CD155, a Vitronectin and Poliovirus Receptor That Localizes to αvβ3 Integrin-containing Membrane Microdomains

2003 • 89 citations

Vav2 as a Rac-GDP/GTP Exchange Factor Responsible for the Nectin-induced, c-Src- and Cdc42-mediated Activation of Rac

2004 • 87 citations

Roles and modes of action of nectins in cell–cell adhesion

2004 • 85 citations

Role of nectin in organization of tight junctions in epithelial cells

2002 • 85 citations

A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM)

2000 • 85 citations

Nectins and nectin‐like molecules: Roles in cell adhesion, polarization, movement, and proliferation

2006 • 85 citations

Interaction of Integrin αvβ3 with Nectin

2006 • 84 citations

Integrin-mediated functional polarization of Caco-2 cells through E-cadherin—actin complexes

2002 • 82 citations

Involvement of Nectin-activated Cdc42 Small G Protein in Organization of Adherens and Tight Junctions in Madin-Darby Canine Kidney Cells

2003 • 80 citations

Cloning of JAM-2 and JAM-3: an Emerging Junctional Adhesion Molecular Family

2000 • 80 citations

Expression and Functional Characterization of the Adhesion Molecule Spermatogenic Immunoglobulin Superfamily in the Mouse Testis1

2003 • 79 citations

Roles of nectins in cell adhesion, migration and polarization

2004 • 75 citations

A novel member of the immunoglobulin gene superfamily expressed in rat carcinoma cell lines.

1994 • 75 citations

Transcriptional activation of the mouse Necl-5/Tage4/PVR/CD155 gene by fibroblast growth factor or oncogenic Ras through the Raf–MEK–ERK–AP-1 pathway

2005 • 73 citations

Involvement of the Annexin II-S100A10 Complex in the Formation of E-cadherin-based Adherens Junctions in Madin-Darby Canine Kidney Cells

2004 • 73 citations

Roles and modes of action of nectins in cell–cell adhesion

2004 • 72 citations

Involvement of the Ras-Ras-activated Rab5 Guanine Nucleotide Exchange Factor RIN2-Rab5 Pathway in the Hepatocyte Growth Factor-induced Endocytosis of E-cadherin

2006 • 70 citations

Contacts between the commissural axons and the floor plate cells are mediated by nectins

2004 • 59 citations

Role of each immunoglobulin-like loop of nectin for its cell–cell adhesion activity

2003 • 59 citations

FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity

2004 • 58 citations

Requirement of nectin, but not cadherin, for formation of claudin-based tight junctions in annexin II-knockdown MDCK cells

2006 • 53 citations

Role of the second immunoglobulin-like loop of nectin in cell–cell adhesion

2002 • 53 citations

Necl-5/Poliovirus Receptor Interacts in cis with Integrin αVβ3 and Regulates Its Clustering and Focal Complex Formation

2007 • 46 citations

Influence of growth factors on neuronal differentiation

1995 • 45 citations

Role of Multiple Bonds Between the Single Cell Adhesion Molecules, Nectin and Cadherin, Revealed by High Sensitive Force Measurements

2006 • 45 citations

Roles of the Intercellular Adhesion Molecule Nectin in Intracellular Signaling

2003 • 44 citations

The expression of nectin-1alpha in normal human skin and various skin tumours

2003 • 43 citations

Involvement of Nectin in Inactivation of Integrin αvβ3 after the Establishment of Cell-Cell Adhesion

2007 • 40 citations

Interaction and localization of Necl‐5 and PDGF receptor β at the leading edges of moving NIH3T3 cells: Implications for directional cell movement

2008 • 38 citations

The expression, regulation and adhesion function of a novel CD molecule, CD226, on human endothelial cells

2003 • 37 citations

Regulation of platelet‐derived growth factor‐induced Ras signaling by poliovirus receptor Necl‐5 and negative growth regulator Sprouty2

2007 • 35 citations

Involvement of integrin‐induced activation of protein kinase C in the formation of adherens junctions

2007 • 34 citations

Tslc1 (Nectin‐Like Molecule‐2) Is Essential for Spermatozoa Motility and Male Fertility

2006 • 32 citations

Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo

2004 • 32 citations

Up-regulation of Loricrin Expression by Cell Adhesion Molecule Nectin-1 through Rap1-ERK Signaling in Keratinocytes

2007 • 31 citations

Linkage Disequilibrium Mapping of the Gene for Margarita Island Ectodermal Dysplasia (ED4) to 11q23

1998 • 30 citations

Ectodomain shedding of nectin-1α by SF/HGF and TPA in MDCK cells

2002 • 30 citations

Recruitment of E‐cadherin associated with α‐ and β‐catenins and p120^ctn to the nectin‐based cell‐cell adhesion sites by the action of 12‐O‐tetradecanoylphorbol‐13‐acetate in MDCK cells

2005 • 27 citations

Localization of occludin, ZO-1, and pan-cadherin in rabbit ciliary epithelium and iris vascular endothelium

2000 • 23 citations

Common signaling pathway is used by the trans‐interaction of Necl‐5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell–cell adhesion

2005 • 21 citations

Platelet derived growth factor/tyrosine kinase receptor mediated proliferation.

1993 • 20 citations

Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells

2006 • 16 citations