Regulation of Endocytosis, Nuclear Translocation, and Signaling of Fibroblast Growth Factor Receptor 1 by E-Cadherin

Epithelial–mesenchymal transitions in tumour progression

2002 • 6,431 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Convergence of Wnt, ß-Catenin, and Cadherin Pathways

2004 • 2,451 citations

Fibroblast growth factors.

2001 • 1,946 citations

Receptor Specificity of the Fibroblast Growth Factor Family

1996 • 1,871 citations

The dynamin superfamily: universal membrane tubulation and fission molecules?

2004 • 1,329 citations

Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

2004 • 1,270 citations

Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 • 1,262 citations

Phosphorylation and Regulation of Raf by Akt (Protein Kinase B)

1999 • 1,084 citations

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

1994 • 948 citations

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

2002 • 817 citations

MOLECULAR AND FUNCTIONAL ANALYSIS OF CADHERIN-BASED ADHERENS JUNCTIONS

1997 • 800 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

FGFs, heparan sulfate and FGFRs: complex interactions essential for development

2000 • 771 citations

Differentiation Stage-Specific Inhibition of the Raf-MEK-ERK Pathway by Akt

1999 • 762 citations

A core function for p120-catenin in cadherin turnover

2003 • 714 citations

FGF Signaling Regulates Mesoderm Cell Fate Specification and Morphogenetic Movement at the Primitive Streak

2001 • 675 citations

The roles of FGFs in the early development of vertebrate limbs

1998 • 659 citations

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion

2003 • 631 citations

The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn

1998 • 566 citations

Recycling of E-Cadherin

1999 • 538 citations

The Zinc-Finger Protein Slug Causes Desmosome Dissociation, an Initial and Necessary Step for Growth Factor–induced Epithelial–Mesenchymal Transition

1997 • 515 citations

A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

2002 • 498 citations

Inhibition of RhoA by p120 catenin

2000 • 459 citations

Signal transduction by fibroblast growth factor receptors

1999 • 419 citations

Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells

2003 • 399 citations

The Catenin p120^ctn Interacts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor

1999 • 396 citations

E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases

2004 • 384 citations

CAM-FGF Receptor Interactions: A Model for Axonal Growth

1996 • 378 citations

The ins and outs of E-cadherin trafficking

2004 • 356 citations

Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling

2002 • 351 citations

Tyrosine phosphorylation and cadherin/catenin function

1997 • 318 citations

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

2001 • 305 citations

Importin β–Mediated Nuclear Import of Fibroblast Growth Factor Receptor

2001 • 226 citations

Adhesion signaling: How β-catenin interacts with its partners

2001 • 225 citations

Dual mode of signal transduction by externally added acidic fibroblast growth factor

1994 • 223 citations

Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2.

1996 • 222 citations

Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

2004 • 184 citations

Characterization of E-cadherin Endocytosis in Isolated MCF-7 and Chinese Hamster Ovary Cells

2003 • 178 citations

A Dileucine Motif Targets E-cadherin to the Basolateral Cell Surface in Madin-Darby Canine Kidney and LLC-PK1 Epithelial Cells

2001 • 172 citations

The Morphogenetic Role of Cadherin Cell Adhesion Molecules in Human Cancer: A Thematic Review

1998 • 141 citations

Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.

1994 • 138 citations

Fibroblast Growth Factor Receptors (FGFRs) Localize in Different Cellular Compartments

1995 • 133 citations

Integrative nuclear FGFR1 signaling (INFS) as a part of a universal “feed‐forward‐and‐gate” signaling module that controls cell growth and differentiation

2003 • 133 citations

Down‐regulation of MEK/ERK signaling by E‐cadherin‐dependent PI3K/Akt pathway in differentiating intestinal epithelial cells

2003 • 100 citations

Role of FGFs in the control of programmed cell death during limb development

2001 • 95 citations

Rac promotes epithelial cell rearrangement during tracheal tubulogenesis inDrosophila

2003 • 94 citations

Integrative nuclear FGFR1 signaling (INFS) pathway mediates activation of the tyrosine hydroxylase gene by angiotensin II, depolarization and protein kinase C

2002 • 93 citations

Tyrosine kinase signalling in breast cancer: Fibroblast growth factors and their receptors

2000 • 90 citations

The Proliferative and Migratory Activities of Breast Cancer Cells Can Be Differentially Regulated by Heparan Sulfates

2000 • 84 citations

Cell Growth Regulation through GM3-enriched Microdomain (Glycosynapse) in Human Lung Embryonal Fibroblast WI38 and Its Oncogenic Transformant VA13

2004 • 84 citations

The Nuclear Trafficking of Extracellular Fibroblast Growth Factor (FGF)-1 Correlates with the Perinuclear Association of the FGF Receptor-1α Isoforms but Not the FGF Receptor-1β Isoforms

1996 • 73 citations

Contextual Binding of p120 to E-cadherin at the Basolateral Plasma Membrane in Polarized Epithelia

2003 • 60 citations

Dynamin-dependent endocytosis is necessary for convergent-extension movements in Xenopus animal cap explants.

2002 • 37 citations

FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines

2001 • 35 citations

The endocytic pathway followed by the keratinocyte growth factor receptor

2002 • 26 citations

Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

2005 • 19 citations

Cell-cell adhesion in invasion and metastasis of carcinomas

1994 • 18 citations