A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts
Data up to Jan 2025
Total Citations Per Year
Abstract
References (57)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 • 47,043 citations
Efficient selection for high-expression transfectants with a novel eukaryotic vector
1991 • 5,120 citations
JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA
1963 • 3,559 citations
Occludin: a novel integral membrane protein localizing at tight junctions.
1993 • 2,466 citations
Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin
1998 • 2,005 citations
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.
1986 • 1,588 citations
Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release.
1979 • 1,408 citations
Structure and Function of Intercellular Junctions
1974 • 1,339 citations
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.
1994 • 949 citations
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.
1996 • 849 citations
Tight junctions and the molecular basis for regulation of paracellular permeability
1995 • 825 citations
VARIATIONS IN TIGHT AND GAP JUNCTIONS IN MAMMALIAN TISSUES
1972 • 674 citations
Expressed recombinant cadherins mediate cell sorting in model systems
1988 • 673 citations
Occludin is a functional component of the tight junction
1996 • 632 citations
ZO-3, a Novel Member of the MAGUK Protein Family Found at the Tight Junction, Interacts with ZO-1 and Occludin
1998 • 592 citations
Possible Involvement of Phosphorylation of Occludin in Tight Junction Formation
1997 • 576 citations
The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy.
1993 • 567 citations
Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions
1998 • 532 citations
Structure, biochemistry, and assembly of epithelial tight junctions
1987 • 532 citations
A Synthetic Peptide Corresponding to the Extracellular Domain of Occludin Perturbs the Tight Junction Permeability Barrier
1997 • 527 citations
Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.
1991 • 520 citations
Structure, function, and regulation of cellular tight junctions
1992 • 517 citations
Cingulin, a new peripheral component of tight junctions
1988 • 505 citations
Further observations on the fine structure of freeze-cleaved tight junctions
1973 • 501 citations
The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions.
1993 • 467 citations
Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein
1994 • 452 citations
Freeze-fracture replica electron microscopy combined with sds digestion for cytochemical labeling of integral membrane proteins: Application to the immunogold labeling of intercellular junctional complexes
1995 • 430 citations
Segmental differentiations of cell junctions in the vascular endothelium. The microvasculature.
1975 • 430 citations
Lipidic intramembranous particles
1984 • 416 citations
Assembly of the tight junction: the role of diacylglycerol.
1993 • 381 citations
Breaking through the tight junction barrier.
1993 • 379 citations
Modulation of tight junction structure in blood-brain barrier endothelial cells Effects of tissue culture, second messengers and cocultured astrocytes
1994 • 361 citations
Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues.
1996 • 329 citations
COOH Terminus of Occludin Is Required for Tight Junction Barrier Function in Early Xenopus Embryos
1997 • 301 citations
Symplekin, a novel type of tight junction plaque protein.
1996 • 286 citations
Mammalian occludin in epithelial cells: its expression and subcellular distribution.
1997 • 278 citations
Evidence for the lipidic nature of tight junction strands
1982 • 277 citations
Occludin confers adhesiveness when expressed in fibroblasts
1997 • 272 citations
Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2.
1993 • 266 citations
Vitamin-A-induced mucous metaplasia. An in vitro system for modulating tight and gap junction differentiation.
1976 • 220 citations
On tight-junction structure
1982 • 218 citations
The molecular organization of tight junctions.
1993 • 201 citations
Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures
1996 • 193 citations
Submembranous junctional plaque proteins include potential tumor suppressor molecules.
1993 • 179 citations
The epithelial tight junction: Structure, function and preliminary biochemical characterization
1988 • 173 citations
Development of blood-brain barrier tight junctions in the rat cortex
1996 • 167 citations
Zonulae occludentes in junctional complex-enriched fractions from mouse liver: preliminary morphological and biochemical characterization.
1984 • 139 citations
Functional significance of the variations in the geometrical organization of tight junction networks.
1976 • 126 citations
Effects of glutaraldehyde fixation on the structure of tight junctions. A quantitative freeze-fracture analysis
1979 • 107 citations
ZO-1 and cingulin: tight junction proteins with distinct identities and localizations
1989 • 105 citations
Cyclic modulation of sertoli cell junctional complexes in a seasonal breeder: The mink (Mustela vison)
1988 • 80 citations
Intercellular junctional complexes of the rat seminiferous tubules: A freeze‐fracture study
1977 • 42 citations
The CLS2 gene encodes a protein with multiple membrane-spanning domains that is important Ca2+ tolerance in yeast
1995 • 40 citations
STRUCTURE OF INTERCELLULAR JUNCTIONS IN DIFFERENT SEGMENTS OF THE INTRAPULMONARY VASCULATURE*
1982 • 28 citations
Further observations on the Sertoli cell junctions of the mouse testis after metal contact freeze‐fracture, and comparisons with cellular junctions of other epithelial cells
1982 • 22 citations
Deleted Work
1955 • 0 citations