Nectins and nectin‐like molecules: Roles in cell adhesion, migration, and polarization

Epithelial–mesenchymal transitions in tumour progression

2002 • 6,431 citations

Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

2002 • 4,097 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

1963 • 3,559 citations

Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis

1996 • 3,454 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

Small GTP-Binding Proteins

2001 • 2,449 citations

Multifunctional strands in tight junctions

2001 • 2,392 citations

CD44: From adhesion molecules to signalling regulators

2003 • 2,236 citations

Morphogenetic roles of classic cadherins

1995 • 1,468 citations

Cellular receptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily

1989 • 1,086 citations

Signalling to and from tight junctions

2003 • 863 citations

Inactivation of the E-Cadherin-Mediated Cell Adhesion System in Human Cancers

1998 • 846 citations

MOLECULAR AND FUNCTIONAL ANALYSIS OF CADHERIN-BASED ADHERENS JUNCTIONS

1997 • 800 citations

Regulation of Cadherin Adhesive Activity

2000 • 793 citations

SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly

2002 • 780 citations

Sticky Business

2003 • 709 citations

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity

2000 • 640 citations

WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell mov

2001 • 594 citations

Nectin and afadin: novel organizers of intercellular junctions

2002 • 574 citations

Epithelial Cell Polarity and Cell Junctions inDrosophila

2001 • 516 citations

Cadherins in embryonic and neural morphogenesis

2000 • 482 citations

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

2003 • 476 citations

TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer

2001 • 438 citations

Activation of the JNK signaling pathway: Breaking the brake on apoptosis

2002 • 432 citations

Intercellular junctions and cellular polarity: the PAR–aPKC complex, a conserved core cassette playing fundamental roles in cell polarity

2001 • 421 citations

Contact inhibition and malignancy

1979 • 386 citations

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl

2003 • 368 citations

Molecular linkage between cadherins and actin filaments in cell—cell adherens junctions

1992 • 359 citations

Spatio-Temporal Regulation of Rac1 Localization and Lamellipodia Dynamics during Epithelial Cell-Cell Adhesion

2002 • 349 citations

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

2003 • 346 citations

The poliovirus receptor protein is produced both as membrane-bound and secreted forms.

1990 • 322 citations

Asymmetric cell division during animal development

2001 • 306 citations

Structural and signalling molecules come together at tight junctions

1999 • 306 citations

Molecular architecture of adherens junctions

2001 • 291 citations

Direct cadherin-activated cell signaling

2002 • 285 citations

Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass

2002 • 281 citations

Regulation of substrate adhesion dynamics during cell motility

2002 • 268 citations

Overexpression of the CD155 gene in human colorectal carcinoma

2001 • 259 citations

Rho family members: Activators of MAP kinase cascades

1995 • 253 citations

Role of Rho family GTPases in epithelial morphogenesis

2002 • 238 citations

Protein Ectodomain Shedding

2002 • 234 citations

Implications of Nectin-like Molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in Cell-Cell Adhesion and Transmembrane Protein Localization in Epithelial Cells

2003 • 222 citations

Mammalian Homolog of Drosophila Tumor Suppressor Lethal (2) Giant Larvae Interacts with Basolateral Exocytic Machinery in Madin-Darby Canine Kidney Cells

2002 • 183 citations

Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer.

2002 • 182 citations

Direct Binding of Cell Polarity Protein PAR-3 to Cell-Cell Adhesion Molecule Nectin at Neuroepithelial Cells of Developing Mouse

2003 • 172 citations

The Tumor Suppressor Protein TSLC1 Is Involved in Cell-Cell Adhesion

2002 • 164 citations

Nectin-1α, an Immunoglobulin-like Receptor Involved in the Formation of Synapses, Is a Substrate for Presenilin/γ-Secretase-like Cleavage

2002 • 163 citations

Molecular Cloning and Characterization of Pals, Proteins Associated with mLin-7

2000 • 156 citations

Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo

1996 • 149 citations

Interaction of the Poliovirus Receptor CD155 with the Dynein Light Chain Tctex-1 and Its Implication for Poliovirus Pathogenesis

2002 • 142 citations

PI 3-Kinases and PTEN

2002 • 134 citations

Tage4/Nectin-like Molecule-5 Heterophilically trans-Interacts with Cell Adhesion Molecule Nectin-3 and Enhances Cell Migration

2003 • 128 citations

Mouse Homolog of Poliovirus Receptor-Related Gene 2 Product, mPRR2, Mediates Homophilic Cell Aggregation

1997 • 123 citations

Involvement of nectin in the localization of junctional adhesion molecule at tight junctions

2002 • 123 citations

A 2-Mb Sequence-Ready Contig Map and a Novel Immunoglobulin Superfamily Gene IGSF4 in the LOH Region of Chromosome 11q23.2

1999 • 120 citations

Genetic control of epithelial cell polarity: Lessons fromDrosophila

2000 • 110 citations

trans-Interactions of Nectins Induce Formation of Filopodia and Lamellipodia through the Respective Activation of Cdc42 and Rac Small G Proteins

2002 • 105 citations

ADIP, a Novel Afadin- and α-Actinin-Binding Protein Localized at Cell-Cell Adherens Junctions

2003 • 100 citations

Cloning and characterization of a novel mouse immunoglobulin superfamily gene expressed in early spermatogenic cells

2001 • 97 citations

The Poliovirus Receptor CD155 Mediates Cell-to-Matrix Contacts by Specifically Binding to Vitronectin

2001 • 95 citations

Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E‐cadherin‐based cell‐cell adhesion

2003 • 90 citations

Recruitment of Nectin-3 to Cell-Cell Junctions through trans-Heterophilic Interaction with CD155, a Vitronectin and Poliovirus Receptor That Localizes to αvβ3 Integrin-containing Membrane Microdomains

2003 • 89 citations

Role of nectin in organization of tight junctions in epithelial cells

2002 • 85 citations

A novel member of the immunoglobulin gene superfamily expressed in rat carcinoma cell lines.

1994 • 75 citations

Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins

2001 • 70 citations

Expression of RA175 mRNA, a new member of the immunoglobulin superfamily, in developing mouse brain

2001 • 62 citations

Role of each immunoglobulin-like loop of nectin for its cell–cell adhesion activity

2003 • 59 citations

Cdc42 and Rac small G proteins activated by trans‐interactions of nectins are involved in activation of c‐Jun N‐terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts

2003 • 48 citations

Over-expression of a novel member of the immunoglobulin superfamily in Min mouse intestinal adenomas

1996 • 44 citations

Regulation by nectin of the velocity of the formation of adherens junctions and tight junctions

2003 • 44 citations

Identification of the Tslc1 gene, a mouse orthologue of the human tumor suppressor TSLC1 gene

2002 • 36 citations

Physical association between CD155 and CD44 in human monocytes

1997 • 35 citations

Role of Nectin in Formation of E-Cadherin–based Adherens Junctions in Keratinocytes: Analysis with the N-Cadherin Dominant Negative Mutant

2003 • 31 citations

Ectodomain shedding of nectin-1α by SF/HGF and TPA in MDCK cells

2002 • 30 citations

Organization of the rat Tage4 gene and herpesvirus entry activity of the encoded protein

2001 • 24 citations

Roles of Nectins in Cell Adhesion, Signaling and Polarization

2004 • 8 citations